| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.137187 |
| VCL | vinculin | 0.136837 |
| NRG1 | neuregulin 1 | 0.0958941 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0922828 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0801656 |
| FMN1 | formin 1 | 0.070343 |
| RNF213 | ring finger protein 213 | 0.0701847 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0579919 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0563094 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0552873 |
| PRKCA | protein kinase C, alpha | 0.0522687 |
| TLE4 | transducin-like enhancer of split 4 | 0.0513061 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0508859 |
| VMP1 | vacuole membrane protein 1 | 0.0470836 |
| DST | dystonin | 0.0457361 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444854 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0444689 |
| LPIN1 | lipin 1 | 0.0431827 |
| RIGI | RNA sensor RIG-I | 0.0421225 |
| MSI2 | musashi RNA-binding protein 2 | 0.0416016 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.038948 |
| EFNA5 | ephrin-A5 | 0.0389475 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0379432 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0378905 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0372969 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0361038 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0359571 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0353142 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0347985 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0345895 |
| KLHL13 | kelch-like family member 13 | 0.0339111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0336308 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0329452 |
| NREP | neuronal regeneration related protein | 0.0326294 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.032543 |
| TPM1 | tropomyosin 1 (alpha) | 0.0325287 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0321392 |
| DGKH | diacylglycerol kinase, eta | 0.03132 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.031067 |
| PLPP1 | phospholipid phosphatase 1 | 0.0309949 |
| THBS1 | thrombospondin 1 | 0.030791 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0305464 |
| FRMD4A | FERM domain containing 4A | 0.0303127 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.030225 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0301058 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0300995 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.030087 |
| SYT1 | synaptotagmin I | 0.02966 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0293882 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0292694 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0291979 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0291007 |
| CADM2 | cell adhesion molecule 2 | 0.0290467 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0288272 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0285671 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0284204 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0283086 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0282272 |
| ITGA1 | integrin, alpha 1 | 0.0281347 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0279555 |
| FHIT | fragile histidine triad | 0.0278757 |
| AHNAK | AHNAK nucleoprotein | 0.0275896 |
| INTS6 | integrator complex subunit 6 | 0.0269171 |
| SETBP1 | SET binding protein 1 | 0.0266595 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0265982 |
| MED13 | mediator complex subunit 13 | 0.0265707 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0255282 |
| DPH6 | diphthamine biosynthesis 6 | 0.0254107 |
| TENM4 | teneurin transmembrane protein 4 | 0.0252102 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0251233 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0249741 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.024863 |
| AOPEP | aminopeptidase O (putative) | 0.0248091 |
| ZNF804A | zinc finger protein 804A | 0.0248083 |
| MCL1 | myeloid cell leukemia 1 | 0.024726 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0245806 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0243352 |
| FAM107B | family with sequence similarity 107, member B | 0.0241808 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0239882 |
| AEBP2 | AE binding protein 2 | 0.0237789 |
| HOMER1 | homer scaffolding protein 1 | 0.0236656 |
| SP100 | SP100 nuclear antigen | 0.0234704 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0227375 |
| TPM4 | tropomyosin 4 | 0.0226618 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.022639 |
| EXOC4 | exocyst complex component 4 | 0.0221903 |
| PDE10A | phosphodiesterase 10A | 0.0217518 |
| UBAP2 | ubiquitin associated protein 2 | 0.021751 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0215913 |
| HSPA8 | heat shock 70kDa protein 8 | 0.021504 |
| GPC5 | glypican 5 | 0.0213049 |
| MRTFA | myocardin related transcription factor A | 0.0211225 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0206472 |
| RAD51B | RAD51 paralog B | 0.020613 |
| CNTN4 | contactin 4 | 0.0206016 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0204968 |
| CUX1 | cut-like homeobox 1 | 0.0198884 |
| COL4A2 | collagen, type IV, alpha 2 | 0.019865 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0197374 |
| PLSCR1 | phospholipid scramblase 1 | 0.0195775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.257648 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18342 |
| IGF2 | insulin-like growth factor 2 | -0.149938 |
| PTMA | prothymosin, alpha | -0.0868233 |
| VIM | vimentin | -0.0845852 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0608941 |
| RPS6 | ribosomal protein S6 | -0.0588611 |
| RPL23 | ribosomal protein L23 | -0.0561379 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0519587 |
| NDRG1 | N-myc downstream regulated 1 | -0.0512059 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0496785 |
| FAM13A | family with sequence similarity 13, member A | -0.0472027 |
| TMSB10 | thymosin beta 10 | -0.0430072 |
| RPLP1 | ribosomal protein, large, P1 | -0.041426 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0408183 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0404403 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0402258 |
| RPL19 | ribosomal protein L19 | -0.0400333 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0383718 |
| RPS3 | ribosomal protein S3 | -0.0371748 |
| CENPF | centromere protein F, 350/400kDa | -0.0366484 |
| RPL37A | ribosomal protein L37a | -0.0364965 |
| FTL | ferritin, light polypeptide | -0.0349272 |
| WDR45B | WD repeat domain 45B | -0.0343066 |
| B2M | beta-2-microglobulin | -0.0334115 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0328936 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0316478 |
| HELZ | helicase with zinc finger | -0.0306114 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0304888 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0301665 |
| FAM162A | family with sequence similarity 162, member A | -0.0297987 |
| RPS19 | ribosomal protein S19 | -0.0287292 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0272379 |
| RACK1 | receptor for activated C kinase 1 | -0.0265572 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262438 |
| CRH | corticotropin releasing hormone | -0.0254704 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0250273 |
| RPS12 | ribosomal protein S12 | -0.0248983 |
| RPL26 | ribosomal protein L26 | -0.0248761 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0248469 |
| H3-3B | H3.3 histone B | -0.0248261 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0246535 |
| GOLGA4 | golgin A4 | -0.0245247 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0244927 |
| MEF2A | myocyte enhancer factor 2A | -0.023889 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0238055 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0236436 |
| ZNF292 | zinc finger protein 292 | -0.023536 |
| RPL36 | ribosomal protein L36 | -0.0234194 |
| RPL27 | ribosomal protein L27 | -0.0233969 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0233218 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0232418 |
| RPL34 | ribosomal protein L34 | -0.0231888 |
| RPL12 | ribosomal protein L12 | -0.0231212 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0230756 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0229114 |
| TBX2 | T-box 2 | -0.0228653 |
| RPL35A | ribosomal protein L35a | -0.0225519 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0225276 |
| RPLP0 | ribosomal protein, large, P0 | -0.0224946 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0219481 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0213243 |
| OGA | O-GlcNAcase | -0.0211591 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0206918 |
| KLF6 | Kruppel-like factor 6 | -0.0205881 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0205763 |
| RPL9 | ribosomal protein L9 | -0.0202271 |
| FNBP1 | formin binding protein 1 | -0.0201638 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0200895 |
| ZNF148 | zinc finger protein 148 | -0.0200296 |
| SRP54 | signal recognition particle 54kDa | -0.0198197 |
| CBX3 | chromobox homolog 3 | -0.0197321 |
| RPS2 | ribosomal protein S2 | -0.0196679 |
| SET | SET nuclear proto-oncogene | -0.0194166 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0193063 |
| NUP58 | nucleoporin 58 | -0.0191744 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0190467 |
| RPL7 | ribosomal protein L7 | -0.0189459 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0188831 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186911 |
| RPS14 | ribosomal protein S14 | -0.0186825 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0184863 |
| QKI | QKI, KH domain containing, RNA binding | -0.0183066 |
| CDC27 | cell division cycle 27 | -0.0182765 |
| RPL32 | ribosomal protein L32 | -0.0181946 |
| RPL31 | ribosomal protein L31 | -0.0179338 |
| RPS24 | ribosomal protein S24 | -0.0178062 |
| RPS5 | ribosomal protein S5 | -0.0175812 |
| HMGB2 | high mobility group box 2 | -0.0174832 |
| HIP1 | huntingtin interacting protein 1 | -0.0174828 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0173791 |
| RPL37 | ribosomal protein L37 | -0.0173687 |
| SCFD1 | sec1 family domain containing 1 | -0.0173318 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0173316 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0172999 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0171187 |
| MAP1B | microtubule-associated protein 1B | -0.0171047 |
| RPL18 | ribosomal protein L18 | -0.0170743 |
| NOP58 | NOP58 ribonucleoprotein | -0.0170254 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0170157 |
