| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.131376 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.128911 |
| LMO7 | LIM domain 7 | 0.111928 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.095342 |
| ANXA2 | annexin A2 | 0.0739795 |
| SQSTM1 | sequestosome 1 | 0.0678455 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.066992 |
| AREG | amphiregulin | 0.0661978 |
| PTMA | prothymosin, alpha | 0.0660206 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0650658 |
| B2M | beta-2-microglobulin | 0.0632608 |
| ACTG1 | actin gamma 1 | 0.0616109 |
| SMAD3 | SMAD family member 3 | 0.061574 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0594056 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0590773 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.058155 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0527663 |
| HLA-B | major histocompatibility complex, class I, B | 0.0523782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.051776 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0503952 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0495761 |
| LCN2 | lipocalin 2 | 0.0477055 |
| EFNB2 | ephrin-B2 | 0.0469875 |
| PERP | PERP, TP53 apoptosis effector | 0.0465391 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0450253 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0446466 |
| RPL34 | ribosomal protein L34 | 0.0439158 |
| SP100 | SP100 nuclear antigen | 0.0420974 |
| SDC4 | syndecan 4 | 0.04178 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0411269 |
| IER3 | immediate early response 3 | 0.0408193 |
| INTS6 | integrator complex subunit 6 | 0.0399173 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0394878 |
| LAMA4 | laminin, alpha 4 | 0.0388184 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0384994 |
| ASPH | aspartate beta-hydroxylase | 0.0384301 |
| XAF1 | XIAP associated factor 1 | 0.0381254 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0376246 |
| RPL35A | ribosomal protein L35a | 0.037463 |
| MAP7 | microtubule-associated protein 7 | 0.036805 |
| HKDC1 | hexokinase domain containing 1 | 0.0367796 |
| VCL | vinculin | 0.0367188 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0359032 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0354039 |
| ABLIM1 | actin binding LIM protein 1 | 0.0350461 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0348914 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0347639 |
| S100A10 | S100 calcium binding protein A10 | 0.0345202 |
| PLSCR2 | phospholipid scramblase 2 | 0.033295 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0325961 |
| CANX | calnexin | 0.0323362 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0316905 |
| PKM | pyruvate kinase, muscle | 0.0315735 |
| LAMB3 | laminin, beta 3 | 0.0315074 |
| SLC38A2 | solute carrier family 38, member 2 | 0.030743 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0305144 |
| RRBP1 | ribosome binding protein 1 | 0.0304791 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0303763 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0293571 |
| RNF213 | ring finger protein 213 | 0.0292819 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0288754 |
| ENO1 | enolase 1, (alpha) | 0.0279579 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0279197 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0274492 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0272165 |
| FTL | ferritin, light polypeptide | 0.027174 |
| RPS6 | ribosomal protein S6 | 0.0271519 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0271444 |
| KYNU | kynureninase | 0.0267757 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0267536 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0264893 |
| MLPH | melanophilin | 0.026285 |
| RPS8 | ribosomal protein S8 | 0.0260475 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0258579 |
| MT2A | metallothionein 2A | 0.025779 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0255479 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0253988 |
| GOLGB1 | golgin B1 | 0.0252202 |
| DSG2 | desmoglein 2 | 0.0250538 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0248959 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0248809 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0247684 |
| BCL2L1 | BCL2-like 1 | 0.0247557 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0245636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0245582 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0245435 |
| PGK1 | phosphoglycerate kinase 1 | 0.024459 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0243373 |
| CALR | calreticulin | 0.024118 |
| MX2 | MX dynamin-like GTPase 2 | 0.024051 |
| RPS24 | ribosomal protein S24 | 0.024005 |
| PUM1 | pumilio RNA-binding family member 1 | 0.023949 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0238547 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0236004 |
| KRT18 | keratin 18, type I | 0.0235704 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0234293 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.023313 |
| HM13 | histocompatibility (minor) 13 | 0.0232838 |
| DIAPH1 | diaphanous-related formin 1 | 0.023262 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0232545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0806757 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0763162 |
| CCNL1 | cyclin L1 | -0.0599964 |
| NCKAP5 | NCK-associated protein 5 | -0.057941 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0568671 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0550569 |
| NDRG1 | N-myc downstream regulated 1 | -0.0502631 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0466535 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0402177 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0387057 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0379813 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0370299 |
| PLSCR1 | phospholipid scramblase 1 | -0.0365398 |
| RAD51B | RAD51 paralog B | -0.0363932 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0361874 |
| GRK3 | G protein-coupled receptor kinase 3 | -0.0357046 |
| ALPK1 | alpha-kinase 1 | -0.0356503 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0353662 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0345023 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0339842 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.033623 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0326434 |
| SPATA13 | spermatogenesis associated 13 | -0.0309368 |
| PTEN | phosphatase and tensin homolog | -0.0305093 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0299443 |
| TRIM2 | tripartite motif containing 2 | -0.029177 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0290121 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0289556 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0284839 |
| MX1 | MX dynamin-like GTPase 1 | -0.0271148 |
| OCLN | occludin | -0.0254259 |
| MECOM | MDS1 and EVI1 complex locus | -0.0253221 |
| FOXP1 | forkhead box P1 | -0.0252841 |
| SLC22A23 | solute carrier family 22, member 23 | -0.0246592 |
| FOSL2 | FOS-like antigen 2 | -0.0245966 |
| TMEM51 | transmembrane protein 51 | -0.0245538 |
| CLDN4 | claudin 4 | -0.0242223 |
| ATXN1 | ataxin 1 | -0.0241673 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0239254 |
| MEIS2 | Meis homeobox 2 | -0.0237786 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0237532 |
| VEGFA | vascular endothelial growth factor A | -0.023574 |
| DHFR | dihydrofolate reductase | -0.0233677 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0230221 |
| CLYBL | citrate lyase beta like | -0.0226336 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0223581 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0222939 |
| GRAMD2B | GRAM domain containing 2B | -0.022157 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0219322 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0217836 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0215277 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0213803 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0209789 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0209675 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0207845 |
| UBAC2 | UBA domain containing 2 | -0.0207266 |
| KIF16B | kinesin family member 16B | -0.0202624 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0202048 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | -0.0202044 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.020164 |
| TPCN1 | two pore segment channel 1 | -0.0200544 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0199912 |
| DIAPH3 | diaphanous-related formin 3 | -0.0196141 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0195815 |
| ZNRF3 | zinc and ring finger 3 | -0.0193948 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0192417 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0191934 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0191647 |
| MYO6 | myosin VI | -0.0190611 |
| FGGY | FGGY carbohydrate kinase domain containing | -0.0190006 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0189622 |
| STK24 | serine/threonine kinase 24 | -0.0188186 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0184081 |
| PRKCA | protein kinase C, alpha | -0.0183724 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0183378 |
| ZNF292 | zinc finger protein 292 | -0.0182909 |
| RBM26 | RNA binding motif protein 26 | -0.0182115 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.01819 |
| DNM2 | dynamin 2 | -0.0180693 |
| RASGEF1B | RasGEF domain family, member 1B | -0.0180283 |
| SYT1 | synaptotagmin I | -0.0174867 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.017454 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0174007 |
| TMC5 | transmembrane channel-like 5 | -0.017364 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0173356 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0173207 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0172408 |
| STK39 | serine threonine kinase 39 | -0.0171801 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0171749 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0171743 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0171198 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0170948 |
| PTK2 | protein tyrosine kinase 2 | -0.0170654 |
| SPATA6L | spermatogenesis associated 6-like | -0.0167647 |
| STIL | SCL/TAL1 interrupting locus | -0.0165116 |
| EZR | ezrin | -0.0164523 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0162888 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0161167 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0159347 |
| VMP1 | vacuole membrane protein 1 | -0.0158957 |
