| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.229275 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.154445 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.106905 |
| ASPH | aspartate beta-hydroxylase | 0.0856544 |
| NAV1 | neuron navigator 1 | 0.0753542 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0678761 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.065187 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0632838 |
| NLGN1 | neuroligin 1 | 0.0610736 |
| PTK2 | protein tyrosine kinase 2 | 0.0569683 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0531963 |
| COL5A1 | collagen, type V, alpha 1 | 0.0505363 |
| VCL | vinculin | 0.0501466 |
| ZNF804A | zinc finger protein 804A | 0.0457285 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0457109 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0449724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0427111 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0359556 |
| FN1 | fibronectin 1 | 0.0357146 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0340803 |
| PRSS23 | protease, serine, 23 | 0.0332571 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0331209 |
| PLEC | plectin | 0.0330731 |
| DST | dystonin | 0.0304813 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0299742 |
| KYNU | kynureninase | 0.0298469 |
| NAV3 | neuron navigator 3 | 0.029547 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.0291449 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0286025 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0282216 |
| FUS | FUS RNA binding protein | 0.0275597 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0273355 |
| ACTG1 | actin gamma 1 | 0.027132 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0267873 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0267777 |
| PRKCA | protein kinase C, alpha | 0.0267507 |
| CALR | calreticulin | 0.0264922 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0263842 |
| CDK14 | cyclin-dependent kinase 14 | 0.0258356 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0257579 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0255604 |
| INTS6 | integrator complex subunit 6 | 0.0251479 |
| AK1 | adenylate kinase 1 | 0.0247594 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0243432 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0243344 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0243154 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0238799 |
| WLS | wntless Wnt ligand secretion mediator | 0.0237926 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.023615 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0234948 |
| DGKI | diacylglycerol kinase, iota | 0.0233952 |
| AJAP1 | adherens junctions associated protein 1 | 0.0231366 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 0.0229856 |
| EXOC4 | exocyst complex component 4 | 0.022756 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0226552 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0225984 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0225936 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0221408 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0219874 |
| FHL2 | four and a half LIM domains 2 | 0.0219625 |
| BPTF | bromodomain PHD finger transcription factor | 0.0218128 |
| HDAC9 | histone deacetylase 9 | 0.0216028 |
| COMMD10 | COMM domain containing 10 | 0.0214505 |
| CUX1 | cut-like homeobox 1 | 0.0213463 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.0211881 |
| WWOX | WW domain containing oxidoreductase | 0.021147 |
| XYLT1 | xylosyltransferase I | 0.0210253 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0209863 |
| IGF2 | insulin-like growth factor 2 | 0.0208615 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0208308 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0207773 |
| RRM2 | ribonucleotide reductase M2 | 0.0206494 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0205474 |
| ATXN1 | ataxin 1 | 0.0205358 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | 0.0204992 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0203729 |
| TENM3 | teneurin transmembrane protein 3 | 0.0203202 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0203188 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0202139 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0200498 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0198984 |
| OXR1 | oxidation resistance 1 | 0.0198424 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0198204 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.019783 |
| MYO1E | myosin IE | 0.0197613 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0197033 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0195129 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0194965 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0193284 |
| PALLD | palladin, cytoskeletal associated protein | 0.0191653 |
| CMIP | c-Maf inducing protein | 0.0190226 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0188464 |
| MCL1 | myeloid cell leukemia 1 | 0.0187713 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0184937 |
| POTEF | POTE ankyrin domain family, member F | 0.0184562 |
| PTCHD4 | patched domain containing 4 | 0.0183773 |
| RBM6 | RNA binding motif protein 6 | 0.0183061 |
| SPMIP6 | sperm microtubule inner protein 6 | 0.0182565 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0181985 |
| SKI | SKI proto-oncogene | 0.0181614 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315234 |
| NDRG1 | N-myc downstream regulated 1 | -0.181227 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.174841 |
| FTL | ferritin, light polypeptide | -0.168362 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0952003 |
| STC1 | stanniocalcin 1 | -0.0794655 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0774059 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0650192 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0642933 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0639477 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0582778 |
| CADM1 | cell adhesion molecule 1 | -0.0573462 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0563572 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0559269 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0557249 |
| FAM13A | family with sequence similarity 13, member A | -0.0546243 |
| MMP12 | matrix metallopeptidase 12 | -0.0524521 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0508999 |
| RTN4 | reticulon 4 | -0.0498146 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0496654 |
| VIM | vimentin | -0.0487002 |
| RPLP1 | ribosomal protein, large, P1 | -0.0480535 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0475836 |
| SMAD3 | SMAD family member 3 | -0.0473301 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0469757 |
| ENO1 | enolase 1, (alpha) | -0.0459523 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.045563 |
| EGR1 | early growth response 1 | -0.0429957 |
| LOX | lysyl oxidase | -0.0427444 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0424163 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0422029 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0421295 |
| GOLGA4 | golgin A4 | -0.0418366 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0415976 |
| ATP13A3 | ATPase type 13A3 | -0.0414573 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0414315 |
| PGK1 | phosphoglycerate kinase 1 | -0.0408446 |
| GOLGB1 | golgin B1 | -0.0403917 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0403809 |
| PKM | pyruvate kinase, muscle | -0.0400101 |
| SEPTIN7 | septin 7 | -0.0393953 |
| RPL28 | ribosomal protein L28 | -0.0390283 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0387905 |
| GLIS3 | GLIS family zinc finger 3 | -0.0386531 |
| INHBA | inhibin, beta A | -0.0386031 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0383454 |
| TXNIP | thioredoxin interacting protein | -0.0380913 |
| RLF | rearranged L-myc fusion | -0.0375449 |
| GLG1 | golgi glycoprotein 1 | -0.0371228 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0364456 |
| SRP54 | signal recognition particle 54kDa | -0.0361603 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.035252 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0347193 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0343581 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0330479 |
| PHF21A | PHD finger protein 21A | -0.031863 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0314706 |
| USP37 | ubiquitin specific peptidase 37 | -0.0313081 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0312993 |
| HDLBP | high density lipoprotein binding protein | -0.0310324 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0307455 |
| FOSL1 | FOS-like antigen 1 | -0.0307092 |
| PCBP2 | poly(rC) binding protein 2 | -0.0304994 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0302873 |
| RACK1 | receptor for activated C kinase 1 | -0.0299958 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0299746 |
| SBF2 | SET binding factor 2 | -0.0297194 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0294755 |
| ANKRD17 | ankyrin repeat domain 17 | -0.029297 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.029052 |
| COPA | coatomer protein complex, subunit alpha | -0.0288494 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0287309 |
| ZNF395 | zinc finger protein 395 | -0.0286865 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0286665 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0286648 |
| RPS12 | ribosomal protein S12 | -0.0279841 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0279531 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0279441 |
| RPS6 | ribosomal protein S6 | -0.0279043 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0276273 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0274174 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0273205 |
| JMJD1C | jumonji domain containing 1C | -0.0271185 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269678 |
| TPI1 | triosephosphate isomerase 1 | -0.0268812 |
| ZNF292 | zinc finger protein 292 | -0.026785 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0267382 |
| SUCO | SUN domain containing ossification factor | -0.0265656 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0258758 |
| RPL12 | ribosomal protein L12 | -0.0257074 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0255615 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0254855 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0251425 |
| SETD5 | SET domain containing 5 | -0.0251274 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0250959 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0249214 |
| CD109 | CD109 molecule | -0.0247673 |
| RBM39 | RNA binding motif protein 39 | -0.0246822 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0246793 |
| SFXN1 | sideroflexin 1 | -0.0246502 |
