| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AHNAK | AHNAK nucleoprotein | 0.151537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103048 |
| INTS6 | integrator complex subunit 6 | 0.0914269 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0797542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0788537 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0639474 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0638807 |
| FUS | FUS RNA binding protein | 0.06334 |
| WWOX | WW domain containing oxidoreductase | 0.0593461 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0581976 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0568339 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0548566 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0538495 |
| SMYD3 | SET and MYND domain containing 3 | 0.053647 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0529876 |
| PLEC | plectin | 0.0514266 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0503307 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0496249 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0436064 |
| LRRC23 | leucine rich repeat containing 23 | 0.0434218 |
| KRT8 | keratin 8, type II | 0.042732 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0388516 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0384945 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0382456 |
| CANX | calnexin | 0.0360716 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0359521 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.035846 |
| FLNA | filamin A, alpha | 0.0357768 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0347613 |
| HDLBP | high density lipoprotein binding protein | 0.0346861 |
| SDC4 | syndecan 4 | 0.0335103 |
| SKI | SKI proto-oncogene | 0.0333812 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0329723 |
| KRT18 | keratin 18, type I | 0.0329563 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0325063 |
| CTBP2 | C-terminal binding protein 2 | 0.0323251 |
| PGK1 | phosphoglycerate kinase 1 | 0.0316098 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0314231 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0311167 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0310085 |
| RRBP1 | ribosome binding protein 1 | 0.0309837 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0308302 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0307966 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0305755 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0305083 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0302917 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.029918 |
| RRM2 | ribonucleotide reductase M2 | 0.0298742 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0286698 |
| KLHL29 | kelch-like family member 29 | 0.0283646 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0283168 |
| RCC1 | regulator of chromosome condensation 1 | 0.0282718 |
| AEBP2 | AE binding protein 2 | 0.0276738 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0276111 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0274271 |
| ASPH | aspartate beta-hydroxylase | 0.0273405 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0271118 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0270233 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0268237 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0267426 |
| LDHA | lactate dehydrogenase A | 0.0266488 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0259431 |
| HOMER1 | homer scaffolding protein 1 | 0.0256519 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0255649 |
| FAM107B | family with sequence similarity 107, member B | 0.0250943 |
| VCL | vinculin | 0.0250799 |
| FHIT | fragile histidine triad | 0.0250297 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247307 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0246757 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.024288 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.024245 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0242285 |
| TGFB1 | transforming growth factor, beta 1 | 0.0240968 |
| PMM2 | phosphomannomutase 2 | 0.0240805 |
| JUN | jun proto-oncogene | 0.0240724 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0240369 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0240108 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0239903 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0239434 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0237162 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0235808 |
| SEPTIN9 | septin 9 | 0.023572 |
| MTAP | methylthioadenosine phosphorylase | 0.0235712 |
| ACTG1 | actin gamma 1 | 0.0235198 |
| CALR | calreticulin | 0.0231741 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0231501 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0230709 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0230618 |
| BAIAP2 | BAI1-associated protein 2 | 0.0230509 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.0229707 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0227639 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0225224 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0222971 |
| CTTN | cortactin | 0.0222506 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0221925 |
| POU2F2 | POU class 2 homeobox 2 | 0.021904 |
| TENM3 | teneurin transmembrane protein 3 | 0.021833 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0216929 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0216375 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0216325 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.300008 |
| NDRG1 | N-myc downstream regulated 1 | -0.117815 |
| GOLGA4 | golgin A4 | -0.107447 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.104484 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0864148 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0765707 |
| ZNF292 | zinc finger protein 292 | -0.0715275 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0665713 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0574504 |
| ARF4 | ADP-ribosylation factor 4 | -0.0571811 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0567158 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0562124 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.055605 |
| HMGA1 | high mobility group AT-hook 1 | -0.0537204 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0483159 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0479849 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0473984 |
| CENPF | centromere protein F, 350/400kDa | -0.047024 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0469436 |
| ENO1 | enolase 1, (alpha) | -0.0464884 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0461719 |
| FTL | ferritin, light polypeptide | -0.0453945 |
| TMF1 | TATA element modulatory factor 1 | -0.0434395 |
| RHOA | ras homolog family member A | -0.042956 |
| PTMA | prothymosin, alpha | -0.0422563 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.042036 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.041599 |
| ZNF654 | zinc finger protein 654 | -0.0406248 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0405411 |
| PCBP2 | poly(rC) binding protein 2 | -0.0401033 |
| SBF2 | SET binding factor 2 | -0.0388285 |
| NUP58 | nucleoporin 58 | -0.0386748 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0381653 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0379181 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0378822 |
| ZNF207 | zinc finger protein 207 | -0.037744 |
| TXNRD1 | thioredoxin reductase 1 | -0.0377145 |
| NKTR | natural killer cell triggering receptor | -0.0376124 |
| SETD5 | SET domain containing 5 | -0.0370087 |
| HELZ | helicase with zinc finger | -0.0363111 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0362357 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0357974 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0351924 |
| MKI67 | marker of proliferation Ki-67 | -0.0348428 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0344894 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0342465 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0339654 |
| SRP54 | signal recognition particle 54kDa | -0.0336635 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0335346 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.033458 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0331335 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0329717 |
| RNF24 | ring finger protein 24 | -0.0321083 |
| RIOK3 | RIO kinase 3 | -0.0318456 |
| POTEF | POTE ankyrin domain family, member F | -0.0318267 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0313667 |
| YEATS2 | YEATS domain containing 2 | -0.0311372 |
| ERBIN | erbb2 interacting protein | -0.0310864 |
| SHROOM3 | shroom family member 3 | -0.0305615 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0304551 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030136 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0297456 |
| PTEN | phosphatase and tensin homolog | -0.0296408 |
| TMEM41B | transmembrane protein 41B | -0.0294986 |
| RBM25 | RNA binding motif protein 25 | -0.0294791 |
| EGR1 | early growth response 1 | -0.0294293 |
| RPS6 | ribosomal protein S6 | -0.0293925 |
| WDR45B | WD repeat domain 45B | -0.0290808 |
| SUCO | SUN domain containing ossification factor | -0.0288863 |
| WASF2 | WAS protein family, member 2 | -0.0285635 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0285054 |
| THOC2 | THO complex 2 | -0.0281935 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0280432 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0280195 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0279212 |
| BBX | bobby sox homolog (Drosophila) | -0.0278667 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0277296 |
| UBXN4 | UBX domain protein 4 | -0.0276719 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0275443 |
| CDK19 | cyclin-dependent kinase 19 | -0.0275397 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0273089 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0272823 |
| MED13 | mediator complex subunit 13 | -0.027263 |
| FNBP4 | formin binding protein 4 | -0.0272092 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0270435 |
| RSF1 | remodeling and spacing factor 1 | -0.026831 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0267687 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | -0.026492 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0264466 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0264047 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0261171 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0260363 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0258537 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0254235 |
| PFN1 | profilin 1 | -0.025166 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0251168 |
| TAPBP | TAP binding protein (tapasin) | -0.0246313 |
| RLF | rearranged L-myc fusion | -0.0244556 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.024444 |
| UFM1 | ubiquitin-fold modifier 1 | -0.024167 |
