| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.106465 |
| COL5A1 | collagen, type V, alpha 1 | 0.0980401 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.097255 |
| PLEC | plectin | 0.0766216 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0762756 |
| NAV1 | neuron navigator 1 | 0.0721161 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0693284 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0562281 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0545301 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0525395 |
| AHNAK | AHNAK nucleoprotein | 0.0496158 |
| SEPTIN9 | septin 9 | 0.0419011 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0409008 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0404299 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0398325 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0396821 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0383254 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0376834 |
| COL6A3 | collagen, type VI, alpha 3 | 0.034891 |
| INTS6 | integrator complex subunit 6 | 0.0339943 |
| VCL | vinculin | 0.0339482 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0335568 |
| FLNA | filamin A, alpha | 0.033503 |
| TNS1 | tensin 1 | 0.0331538 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0304647 |
| RPLP1 | ribosomal protein, large, P1 | 0.0301802 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0300095 |
| CAVIN1 | caveolae associated protein 1 | 0.0292535 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0289995 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0286526 |
| NAV2 | neuron navigator 2 | 0.0282856 |
| COL6A2 | collagen, type VI, alpha 2 | 0.027688 |
| RPL35A | ribosomal protein L35a | 0.0271716 |
| SQSTM1 | sequestosome 1 | 0.0267746 |
| RPL37A | ribosomal protein L37a | 0.0266783 |
| IL11 | interleukin 11 | 0.0265466 |
| ACTG1 | actin gamma 1 | 0.0264773 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0264089 |
| RPS8 | ribosomal protein S8 | 0.0253701 |
| WWOX | WW domain containing oxidoreductase | 0.0249889 |
| ACTN4 | actinin, alpha 4 | 0.0247407 |
| HMGA2 | high mobility group AT-hook 2 | 0.024689 |
| MT1E | metallothionein 1E | 0.0242439 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0240363 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0238645 |
| LRRC23 | leucine rich repeat containing 23 | 0.0237164 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0232927 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0232613 |
| RPL23 | ribosomal protein L23 | 0.0226463 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0223432 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0220758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0220137 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0218407 |
| RPL31 | ribosomal protein L31 | 0.0218267 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0217341 |
| AEBP2 | AE binding protein 2 | 0.0217324 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0216622 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.021652 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0216166 |
| SHISA5 | shisa family member 5 | 0.0215245 |
| MLPH | melanophilin | 0.0213881 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0212335 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.020961 |
| RCOR1 | REST corepressor 1 | 0.0209141 |
| FRMD4A | FERM domain containing 4A | 0.0208639 |
| PRKCA | protein kinase C, alpha | 0.0208504 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0207422 |
| ACTN1 | actinin, alpha 1 | 0.020371 |
| GPC5 | glypican 5 | 0.0202362 |
| SKI | SKI proto-oncogene | 0.0202047 |
| RASA3 | RAS p21 protein activator 3 | 0.0201331 |
| RPS27A | ribosomal protein S27a | 0.0200842 |
| RPL38 | ribosomal protein L38 | 0.0200033 |
| LAMB3 | laminin, beta 3 | 0.019636 |
| RPS6 | ribosomal protein S6 | 0.0195979 |
| RPS24 | ribosomal protein S24 | 0.0195339 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0194504 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0191556 |
| FUS | FUS RNA binding protein | 0.0189495 |
| ASPH | aspartate beta-hydroxylase | 0.0187742 |
| RPS16 | ribosomal protein S16 | 0.0184339 |
| HDAC4 | histone deacetylase 4 | 0.0180939 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.01806 |
| BAIAP2 | BAI1-associated protein 2 | 0.0179477 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.017869 |
| HLA-B | major histocompatibility complex, class I, B | 0.0178404 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0177523 |
| CAPRIN2 | caprin family member 2 | 0.0175018 |
| FAT1 | FAT atypical cadherin 1 | 0.0174839 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0173727 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0172504 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0169385 |
| RPL9 | ribosomal protein L9 | 0.0167344 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0167338 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0167098 |
| CCDC138 | coiled-coil domain containing 138 | 0.0167068 |
| SLC25A51 | solute carrier family 25, member 51 | 0.0164906 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0163482 |
| EGFR | epidermal growth factor receptor | 0.0162199 |
| DOCK5 | dedicator of cytokinesis 5 | 0.01609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.32418 |
| FN1 | fibronectin 1 | -0.269931 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.24396 |
| VIM | vimentin | -0.176307 |
| NDRG1 | N-myc downstream regulated 1 | -0.0957934 |
| IGF2 | insulin-like growth factor 2 | -0.0870678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0849492 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0845847 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0835548 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0739167 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0640583 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0637391 |
| LOX | lysyl oxidase | -0.0601711 |
| FAM13A | family with sequence similarity 13, member A | -0.0588656 |
| CDCP1 | CUB domain containing protein 1 | -0.0576884 |
| TMSB10 | thymosin beta 10 | -0.0540017 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0528409 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0501361 |
| STC1 | stanniocalcin 1 | -0.0501306 |
| NGLY1 | N-glycanase 1 | -0.0466748 |
| TENM2 | teneurin transmembrane protein 2 | -0.0461213 |
| CD109 | CD109 molecule | -0.0452178 |
| RNF24 | ring finger protein 24 | -0.0445955 |
| SBF2 | SET binding factor 2 | -0.0430994 |
| SETD5 | SET domain containing 5 | -0.0429226 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0414037 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0408875 |
| PGK1 | phosphoglycerate kinase 1 | -0.0395867 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0394213 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0387927 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0386095 |
| SPAG9 | sperm associated antigen 9 | -0.0376137 |
| RTN4 | reticulon 4 | -0.0375613 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0374973 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0370032 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0360354 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0356775 |
| CD44 | CD44 molecule (Indian blood group) | -0.0347875 |
| TXNIP | thioredoxin interacting protein | -0.0341649 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0336068 |
| GLIS3 | GLIS family zinc finger 3 | -0.0334072 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0331786 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0317692 |
| ZNF292 | zinc finger protein 292 | -0.0316202 |
| USP3 | ubiquitin specific peptidase 3 | -0.03142 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0309083 |
| GOLGA4 | golgin A4 | -0.030654 |
| PDE10A | phosphodiesterase 10A | -0.030585 |
| ZNF148 | zinc finger protein 148 | -0.0303987 |
| RAI14 | retinoic acid induced 14 | -0.0303218 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0302024 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0286348 |
| TMEM165 | transmembrane protein 165 | -0.028504 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0284592 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0283863 |
| PTMA | prothymosin, alpha | -0.0279416 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.027273 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0272388 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0266564 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0265059 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0258714 |
| IL1B | interleukin 1, beta | -0.0258491 |
| ENO1 | enolase 1, (alpha) | -0.0253028 |
| WDR45B | WD repeat domain 45B | -0.0252651 |
| CENPF | centromere protein F, 350/400kDa | -0.0250969 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0248484 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0248267 |
| SEC24A | SEC24 family member A | -0.0248064 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0247969 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0247197 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.024694 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0240267 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0239268 |
| COPA | coatomer protein complex, subunit alpha | -0.0238931 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0238434 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.023693 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235839 |
| SRP54 | signal recognition particle 54kDa | -0.0233735 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0233521 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0229264 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0229045 |
| RNF145 | ring finger protein 145 | -0.0228606 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0227668 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0224912 |
| LDHA | lactate dehydrogenase A | -0.0221855 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022098 |
| TAGLN2 | transgelin 2 | -0.0219481 |
| PFN1 | profilin 1 | -0.0217346 |
| INSIG2 | insulin induced gene 2 | -0.0212313 |
| NF1 | neurofibromin 1 | -0.0212004 |
| WASF2 | WAS protein family, member 2 | -0.0211533 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0209913 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0209249 |
| ATP13A3 | ATPase type 13A3 | -0.0204319 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0201842 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0201779 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0200092 |
| GLG1 | golgi glycoprotein 1 | -0.019811 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0196183 |
| SYAP1 | synapse associated protein 1 | -0.0196086 |
