| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | 0.363012 |
| FN1 | fibronectin 1 | 0.215562 |
| COL1A2 | collagen, type I, alpha 2 | 0.193513 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.135698 |
| COL6A3 | collagen, type VI, alpha 3 | 0.11103 |
| TPM4 | tropomyosin 4 | 0.0525292 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0514815 |
| CALD1 | caldesmon 1 | 0.0490676 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0485046 |
| ACTG1 | actin gamma 1 | 0.0458727 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0458316 |
| ATP13A3 | ATPase type 13A3 | 0.0457917 |
| ANKRD11 | ankyrin repeat domain 11 | 0.042703 |
| LOX | lysyl oxidase | 0.0421847 |
| PLEC | plectin | 0.041762 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0390791 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.037928 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0375561 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0358747 |
| INHBA | inhibin, beta A | 0.0346656 |
| VCAN | versican | 0.0341347 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0335314 |
| SDC2 | syndecan 2 | 0.0328974 |
| RND3 | Rho family GTPase 3 | 0.0313791 |
| SPAG9 | sperm associated antigen 9 | 0.0310212 |
| FLNA | filamin A, alpha | 0.0297958 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0284926 |
| HMCN1 | hemicentin 1 | 0.0284867 |
| TMSB4X | thymosin beta 4, X-linked | 0.0281324 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0279045 |
| COPA | coatomer protein complex, subunit alpha | 0.0266501 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0265803 |
| S100A10 | S100 calcium binding protein A10 | 0.0264729 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0260494 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0256051 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024943 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0247478 |
| IL6ST | interleukin 6 signal transducer | 0.0240443 |
| SP100 | SP100 nuclear antigen | 0.023746 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0235917 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0231833 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0227967 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0225882 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0225273 |
| RRBP1 | ribosome binding protein 1 | 0.0224949 |
| VIM | vimentin | 0.0224267 |
| FBN1 | fibrillin 1 | 0.0223715 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0222121 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0221232 |
| TUBB | tubulin, beta class I | 0.0220074 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0216822 |
| HDLBP | high density lipoprotein binding protein | 0.0215921 |
| PXDN | peroxidasin | 0.0214992 |
| AHNAK | AHNAK nucleoprotein | 0.0205769 |
| CAVIN1 | caveolae associated protein 1 | 0.0202686 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0199212 |
| COL3A1 | collagen, type III, alpha 1 | 0.019724 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.01967 |
| S100A9 | S100 calcium binding protein A9 | 0.0195689 |
| TFG | TRK-fused gene | 0.0191763 |
| CCNY | cyclin Y | 0.019071 |
| VCL | vinculin | 0.0190029 |
| NEK10 | NIMA-related kinase 10 | 0.0189886 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0189821 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0189811 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0189416 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0184752 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182755 |
| FUS | FUS RNA binding protein | 0.0182108 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0180627 |
| ZNF644 | zinc finger protein 644 | 0.017799 |
| RASAL2 | RAS protein activator like 2 | 0.0177207 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0177172 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0175376 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0175348 |
| ACTN1 | actinin, alpha 1 | 0.0173716 |
| RIGI | RNA sensor RIG-I | 0.0172664 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0171846 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0169897 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0169823 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0169774 |
| LAMB3 | laminin, beta 3 | 0.016904 |
| THY1 | Thy-1 cell surface antigen | 0.0168777 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0168115 |
| PRRX1 | paired related homeobox 1 | 0.0165699 |
| URI1 | URI1, prefoldin-like chaperone | 0.0165635 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0165258 |
| TBC1D10A | TBC1 domain family, member 10A | 0.0163039 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0162853 |
| PARD3 | par-3 family cell polarity regulator | 0.016098 |
| USP36 | ubiquitin specific peptidase 36 | 0.0160867 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0158365 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0157495 |
| SAFB2 | scaffold attachment factor B2 | 0.0157013 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0156966 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.015494 |
| OSMR | oncostatin M receptor | 0.0154677 |
| SNX9 | sorting nexin 9 | 0.0153711 |
| TMEM39A | transmembrane protein 39A | 0.0153668 |
| MYO10 | myosin X | 0.0153241 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.273987 |
| NDRG1 | N-myc downstream regulated 1 | -0.143047 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.100388 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0957193 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0957135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.077914 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0757221 |
| FTL | ferritin, light polypeptide | -0.0737326 |
| TMSB10 | thymosin beta 10 | -0.0714667 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0710374 |
| B2M | beta-2-microglobulin | -0.0692164 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0610279 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.057732 |
| STC1 | stanniocalcin 1 | -0.0572055 |
| RPS3 | ribosomal protein S3 | -0.0571384 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0560249 |
| HMGA2 | high mobility group AT-hook 2 | -0.0531258 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0510186 |
| RPS6 | ribosomal protein S6 | -0.0508031 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0495639 |
| PTMA | prothymosin, alpha | -0.0480399 |
| RPS12 | ribosomal protein S12 | -0.0479107 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0473721 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0469492 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0456637 |
| ENO1 | enolase 1, (alpha) | -0.0449893 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0441221 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0428546 |
| RPL37A | ribosomal protein L37a | -0.0398502 |
| RPS19 | ribosomal protein S19 | -0.0396848 |
| RPL23 | ribosomal protein L23 | -0.0377496 |
| LDHA | lactate dehydrogenase A | -0.0376511 |
| EFNA5 | ephrin-A5 | -0.0375988 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0356084 |
| RPL36 | ribosomal protein L36 | -0.03529 |
| EGFR | epidermal growth factor receptor | -0.035135 |
| RPS8 | ribosomal protein S8 | -0.0346354 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0344746 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0341213 |
| RPL31 | ribosomal protein L31 | -0.0329852 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.032861 |
| RACK1 | receptor for activated C kinase 1 | -0.0316813 |
| RPS14 | ribosomal protein S14 | -0.0307657 |
| LOXL2 | lysyl oxidase-like 2 | -0.0303211 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0290562 |
| EPHB1 | EPH receptor B1 | -0.0283113 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.027451 |
| PGK1 | phosphoglycerate kinase 1 | -0.0270158 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026672 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0262176 |
| SMYD3 | SET and MYND domain containing 3 | -0.0259793 |
| PRELID2 | PRELI domain containing 2 | -0.0258487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0258281 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0254637 |
| RPL18 | ribosomal protein L18 | -0.0254483 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0251565 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251431 |
| CANX | calnexin | -0.0244317 |
| RPL12 | ribosomal protein L12 | -0.0238568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0237328 |
| RPL19 | ribosomal protein L19 | -0.0233831 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0233672 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0232468 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0228362 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.022641 |
| PDE10A | phosphodiesterase 10A | -0.0221036 |
| RPS2 | ribosomal protein S2 | -0.0220505 |
| MYDGF | myeloid-derived growth factor | -0.0219818 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0219811 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0218727 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0217187 |
| BNC2 | basonuclin 2 | -0.0216139 |
| RPL9 | ribosomal protein L9 | -0.0214517 |
| RPS17 | ribosomal protein S17 | -0.0212513 |
| CDH13 | cadherin 13 | -0.0211369 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0208436 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0206413 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0205171 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0204699 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0203294 |
| ANGPTL4 | angiopoietin-like 4 | -0.0202651 |
| RPL37 | ribosomal protein L37 | -0.0201456 |
| SEC61G | Sec61 gamma subunit | -0.0197912 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0195142 |
| CD63 | CD63 molecule | -0.019403 |
| RPLP1 | ribosomal protein, large, P1 | -0.0193611 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0192226 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0191083 |
| CALR | calreticulin | -0.01908 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0190632 |
| RPL11 | ribosomal protein L11 | -0.0190505 |
| SET | SET nuclear proto-oncogene | -0.0190253 |
| ARF4 | ADP-ribosylation factor 4 | -0.0190193 |
| NBEAL1 | neurobeachin-like 1 | -0.0190067 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.01898 |
| CST3 | cystatin C | -0.0189344 |
| DSTN | destrin (actin depolymerizing factor) | -0.018762 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0187534 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0185094 |
| RPL30 | ribosomal protein L30 | -0.0184465 |
