| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.143418 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0924994 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0750001 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0530009 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0494827 |
| ATXN1 | ataxin 1 | 0.0429988 |
| ASPH | aspartate beta-hydroxylase | 0.0429445 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0425385 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0391956 |
| FRMD5 | FERM domain containing 5 | 0.0331362 |
| RNF213 | ring finger protein 213 | 0.0287868 |
| TNS1 | tensin 1 | 0.0283785 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0279641 |
| DTNA | dystrobrevin, alpha | 0.0273537 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0272692 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0252037 |
| EHBP1 | EH domain binding protein 1 | 0.0249816 |
| GK | glycerol kinase | 0.0238712 |
| ATP10A | ATPase, class V, type 10A | 0.0229848 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0226574 |
| INTS6 | integrator complex subunit 6 | 0.02236 |
| KIAA1217 | KIAA1217 | 0.0219861 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0217669 |
| FAM107B | family with sequence similarity 107, member B | 0.0208861 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0207158 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0206944 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0200553 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0200524 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0198672 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0198006 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0187476 |
| HPCAL1 | hippocalcin-like 1 | 0.0186415 |
| CANX | calnexin | 0.0178758 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0175154 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0172267 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0168876 |
| FAM13A | family with sequence similarity 13, member A | 0.0167073 |
| RIGI | RNA sensor RIG-I | 0.0163774 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0162218 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0161278 |
| FMNL2 | formin-like 2 | 0.0157799 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0153347 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0151738 |
| FUS | FUS RNA binding protein | 0.0151096 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0150523 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0148851 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0148395 |
| NDRG1 | N-myc downstream regulated 1 | 0.0145132 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.014474 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0142165 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0140079 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0138282 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0138018 |
| CCNY | cyclin Y | 0.0137193 |
| INSIG2 | insulin induced gene 2 | 0.0137031 |
| KYNU | kynureninase | 0.0135572 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0134918 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.013453 |
| HDAC4 | histone deacetylase 4 | 0.0134155 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0134084 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0128874 |
| SP100 | SP100 nuclear antigen | 0.0127235 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0126558 |
| MYO1B | myosin IB | 0.0126004 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0125051 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0123973 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0123305 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0122573 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0120866 |
| FBXO42 | F-box protein 42 | 0.0119686 |
| DUSP16 | dual specificity phosphatase 16 | 0.0119557 |
| HOMER1 | homer scaffolding protein 1 | 0.0119001 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0118666 |
| SQSTM1 | sequestosome 1 | 0.0118573 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0118135 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0117922 |
| PLXDC2 | plexin domain containing 2 | 0.0117282 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0115692 |
| HM13 | histocompatibility (minor) 13 | 0.011524 |
| USP37 | ubiquitin specific peptidase 37 | 0.0114979 |
| PLEC | plectin | 0.0114794 |
| NABP1 | nucleic acid binding protein 1 | 0.0113653 |
| NGLY1 | N-glycanase 1 | 0.0113385 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0113318 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0113109 |
| FAM219A | family with sequence similarity 219, member A | 0.0112949 |
| MYO6 | myosin VI | 0.0112343 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0111188 |
| RAD51B | RAD51 paralog B | 0.011058 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0110131 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.01096 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0107475 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0106199 |
| PGM3 | phosphoglucomutase 3 | 0.0106002 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0105511 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0104822 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0103984 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0103734 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0103141 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0102832 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.565054 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.251851 |
| C3 | complement component 3 | -0.193164 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.168713 |
| APOB | apolipoprotein B | -0.143569 |
| MT2A | metallothionein 2A | -0.116739 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.100671 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0830991 |
| FN1 | fibronectin 1 | -0.0771104 |
| GPC3 | glypican 3 | -0.0737663 |
| RPS6 | ribosomal protein S6 | -0.066164 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0631078 |
| RPS12 | ribosomal protein S12 | -0.0616531 |
| FTL | ferritin, light polypeptide | -0.0578096 |
| RPL11 | ribosomal protein L11 | -0.0543221 |
| ENO1 | enolase 1, (alpha) | -0.0516268 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0462913 |
| TF | transferrin | -0.0450042 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0440637 |
| RPL37A | ribosomal protein L37a | -0.04256 |
| RPS19 | ribosomal protein S19 | -0.0414122 |
| RPS8 | ribosomal protein S8 | -0.040922 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0406947 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0380097 |
| RPLP1 | ribosomal protein, large, P1 | -0.0379519 |
| RPS3 | ribosomal protein S3 | -0.0371554 |
| TRIM26 | tripartite motif containing 26 | -0.0358396 |
| RPL12 | ribosomal protein L12 | -0.0342949 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336331 |
| CPE | carboxypeptidase E | -0.033302 |
| RPL31 | ribosomal protein L31 | -0.0329778 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0325223 |
| DSPP | dentin sialophosphoprotein | -0.032212 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.031781 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0316149 |
| RPLP0 | ribosomal protein, large, P0 | -0.0311184 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0310649 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0302693 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0300645 |
| RPL35A | ribosomal protein L35a | -0.0299519 |
| TMSB10 | thymosin beta 10 | -0.0297077 |
| APOE | apolipoprotein E | -0.0291887 |
| CFB | complement factor B | -0.029062 |
| RPL26 | ribosomal protein L26 | -0.0286981 |
| RACK1 | receptor for activated C kinase 1 | -0.0284678 |
| RPS24 | ribosomal protein S24 | -0.0278198 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0276575 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0274956 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0274039 |
| EGR1 | early growth response 1 | -0.0272264 |
| ARHGAP9 | Rho GTPase activating protein 9 | -0.0271793 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266101 |
| RPL34 | ribosomal protein L34 | -0.0264807 |
| RPS27A | ribosomal protein S27a | -0.0262378 |
| RPL23 | ribosomal protein L23 | -0.0258978 |
| RPS14 | ribosomal protein S14 | -0.0254933 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0254675 |
| APOA1 | apolipoprotein A-I | -0.0253972 |
| A2M | alpha-2-macroglobulin | -0.0249893 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.024828 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246983 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0245821 |
| LYZ | lysozyme | -0.0245373 |
| RPS23 | ribosomal protein S23 | -0.0241824 |
| B2M | beta-2-microglobulin | -0.0239886 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0237419 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.023362 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0233311 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0228363 |
| AHSG | alpha-2-HS-glycoprotein | -0.0227494 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0226884 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.022495 |
| APOA2 | apolipoprotein A-II | -0.0223565 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0223396 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.022213 |
| RPS17 | ribosomal protein S17 | -0.0219925 |
| GDF15 | growth differentiation factor 15 | -0.0217343 |
| RPL5 | ribosomal protein L5 | -0.0213668 |
| RPS13 | ribosomal protein S13 | -0.021051 |
| PERP | PERP, TP53 apoptosis effector | -0.0209258 |
| RPL37 | ribosomal protein L37 | -0.0209017 |
| RPS5 | ribosomal protein S5 | -0.0207078 |
| ITGAV | integrin, alpha V | -0.0206985 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0206873 |
| PTCHD4 | patched domain containing 4 | -0.0206161 |
| KIF5B | kinesin family member 5B | -0.0205973 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.020533 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0204336 |
| RTN4 | reticulon 4 | -0.0203727 |
| MALT1 | MALT1 paracaspase | -0.0203344 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0203188 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0202902 |
| RPL9 | ribosomal protein L9 | -0.0201929 |
| RPL32 | ribosomal protein L32 | -0.0201287 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0199919 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0197988 |
| RBM25 | RNA binding motif protein 25 | -0.0195649 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.019338 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0191875 |
| PCBP2 | poly(rC) binding protein 2 | -0.0191492 |
