| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0902415 |
| INTS6 | integrator complex subunit 6 | 0.0642724 |
| NAV2 | neuron navigator 2 | 0.0585439 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0553183 |
| TLE4 | transducin-like enhancer of split 4 | 0.0543451 |
| POTEF | POTE ankyrin domain family, member F | 0.0537885 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0529889 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0525477 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0489211 |
| DEK | DEK proto-oncogene | 0.0488863 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0486447 |
| SMAD3 | SMAD family member 3 | 0.0476875 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.047451 |
| FLNA | filamin A, alpha | 0.0461997 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0458653 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0454175 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0433893 |
| NDRG1 | N-myc downstream regulated 1 | 0.0419211 |
| RPL35A | ribosomal protein L35a | 0.0418236 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0410121 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0407054 |
| VIM | vimentin | 0.0401755 |
| RNF213 | ring finger protein 213 | 0.0395075 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0381567 |
| KRT7 | keratin 7, type II | 0.0380621 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0380192 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0361626 |
| PLEC | plectin | 0.0358001 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0357541 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0354621 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0353037 |
| ACTG1 | actin gamma 1 | 0.0340724 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.033747 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0333135 |
| VCL | vinculin | 0.0332905 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330558 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0328711 |
| FUS | FUS RNA binding protein | 0.0324973 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0319328 |
| GOLGB1 | golgin B1 | 0.0314214 |
| COL5A1 | collagen, type V, alpha 1 | 0.0309344 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0307654 |
| CCDC80 | coiled-coil domain containing 80 | 0.0306426 |
| MYOF | myoferlin | 0.0304077 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0303414 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0301843 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0300535 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0297142 |
| CMIP | c-Maf inducing protein | 0.0296793 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0292529 |
| PLSCR1 | phospholipid scramblase 1 | 0.0289776 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0287958 |
| TPM1 | tropomyosin 1 (alpha) | 0.0287726 |
| UBAP2 | ubiquitin associated protein 2 | 0.0286311 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0284436 |
| FNIP1 | folliculin interacting protein 1 | 0.0280204 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0277098 |
| RND3 | Rho family GTPase 3 | 0.027627 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0274023 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273862 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0272652 |
| MAP4 | microtubule-associated protein 4 | 0.0271836 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0271598 |
| VEGFA | vascular endothelial growth factor A | 0.0267998 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0264286 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.026279 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0262595 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0250518 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0250367 |
| ATXN1 | ataxin 1 | 0.0250173 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0247788 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0246882 |
| TUFT1 | tuftelin 1 | 0.0246206 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0243484 |
| BRD4 | bromodomain containing 4 | 0.0239534 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236088 |
| BRD2 | bromodomain containing 2 | 0.0236017 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0235758 |
| DST | dystonin | 0.0235522 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0229533 |
| CREBBP | CREB binding protein | 0.0227652 |
| MYO1E | myosin IE | 0.0226617 |
| PTK2 | protein tyrosine kinase 2 | 0.0225534 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0225481 |
| ERBIN | erbb2 interacting protein | 0.0223813 |
| TENM3 | teneurin transmembrane protein 3 | 0.0223178 |
| RASAL2 | RAS protein activator like 2 | 0.0222371 |
| RPL7A | ribosomal protein L7a | 0.0221947 |
| ASPH | aspartate beta-hydroxylase | 0.0221707 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0221368 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0221325 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0220759 |
| STC2 | stanniocalcin 2 | 0.0220171 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0218095 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0216282 |
| SQSTM1 | sequestosome 1 | 0.021383 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0213433 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0212536 |
| MSN | moesin | 0.0212482 |
| SEPTIN9 | septin 9 | 0.0212431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.23844 |
| MT2A | metallothionein 2A | -0.204519 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.112451 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0810767 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0808544 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0633429 |
| LDHA | lactate dehydrogenase A | -0.0564399 |
| B2M | beta-2-microglobulin | -0.0547506 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0522755 |
| HLA-A | major histocompatibility complex, class I, A | -0.0512659 |
| RAI14 | retinoic acid induced 14 | -0.0501572 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0487466 |
| HLA-B | major histocompatibility complex, class I, B | -0.0470492 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0416221 |
| HMGB2 | high mobility group box 2 | -0.0416058 |
| ATP13A3 | ATPase type 13A3 | -0.0414043 |
| ZNF841 | zinc finger protein 841 | -0.0413745 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0390918 |
| PGK1 | phosphoglycerate kinase 1 | -0.038327 |
| SET | SET nuclear proto-oncogene | -0.0372923 |
| ENO1 | enolase 1, (alpha) | -0.0372087 |
| OSMR | oncostatin M receptor | -0.0348952 |
| CD44 | CD44 molecule (Indian blood group) | -0.0341116 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0328355 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0322135 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0310428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0308912 |
| HLA-C | major histocompatibility complex, class I, C | -0.0308189 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0304638 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0304464 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0303777 |
| RPS3 | ribosomal protein S3 | -0.0302193 |
| ANGPTL4 | angiopoietin-like 4 | -0.0298523 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0295908 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.027849 |
| FN1 | fibronectin 1 | -0.0276841 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0260978 |
| IL6ST | interleukin 6 signal transducer | -0.0258067 |
| CDK17 | cyclin-dependent kinase 17 | -0.0244551 |
| KLF6 | Kruppel-like factor 6 | -0.0244499 |
| RPL12 | ribosomal protein L12 | -0.0241632 |
| RPL26 | ribosomal protein L26 | -0.0237283 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0218095 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0212936 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0210526 |
| RACK1 | receptor for activated C kinase 1 | -0.0208138 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0207058 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0204537 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0201684 |
| NPPB | natriuretic peptide B | -0.0199715 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0197088 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0196617 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0193623 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0192492 |
| NEK7 | NIMA-related kinase 7 | -0.0191899 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0187587 |
| TMEM41B | transmembrane protein 41B | -0.0187044 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0182932 |
| RPL30 | ribosomal protein L30 | -0.0178177 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0177635 |
| GOLT1B | golgi transport 1B | -0.0175852 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0175479 |
| FAM162A | family with sequence similarity 162, member A | -0.0170483 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0166667 |
| KIF5B | kinesin family member 5B | -0.0166133 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0165993 |
| TPI1 | triosephosphate isomerase 1 | -0.0165915 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0164296 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0163078 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.01626 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0155104 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0154666 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0153461 |
| TMSB10 | thymosin beta 10 | -0.0152088 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.01481 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0147563 |
| RASA2 | RAS p21 protein activator 2 | -0.0147029 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0146622 |
| RRM1 | ribonucleotide reductase M1 | -0.0145332 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0144573 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0144373 |
| RPL11 | ribosomal protein L11 | -0.0143469 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.014197 |
| RPS12 | ribosomal protein S12 | -0.0141382 |
| GLIS3 | GLIS family zinc finger 3 | -0.0139926 |
| FOXP1 | forkhead box P1 | -0.0139118 |
| SSR1 | signal sequence receptor, alpha | -0.013726 |
| RPS17 | ribosomal protein S17 | -0.013599 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.013553 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.013442 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0134237 |
| RPL35 | ribosomal protein L35 | -0.0134204 |
| DTNA | dystrobrevin, alpha | -0.0133118 |
| CANX | calnexin | -0.0132242 |
| ABI2 | abl-interactor 2 | -0.0132062 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0131281 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0131089 |
| TPM3 | tropomyosin 3 | -0.0131051 |
| PDCD10 | programmed cell death 10 | -0.0129714 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0129515 |