| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | 0.0412345 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0383898 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0349035 |
| RPL37A | ribosomal protein L37a | 0.0279135 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0268575 |
| RPS27A | ribosomal protein S27a | 0.0268177 |
| RPS29 | ribosomal protein S29 | 0.0247123 |
| RPL31 | ribosomal protein L31 | 0.0234017 |
| RPS8 | ribosomal protein S8 | 0.0231601 |
| INTS6 | integrator complex subunit 6 | 0.0219535 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0219452 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0217858 |
| ACTG1 | actin gamma 1 | 0.0216445 |
| RPL38 | ribosomal protein L38 | 0.0211146 |
| WDR45B | WD repeat domain 45B | 0.0210153 |
| RPS16 | ribosomal protein S16 | 0.0207346 |
| TEX14 | testis expressed 14 | 0.0205683 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0204993 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0189945 |
| RPLP2 | ribosomal protein, large, P2 | 0.0182809 |
| NUP58 | nucleoporin 58 | 0.0178606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0173789 |
| SQSTM1 | sequestosome 1 | 0.0173116 |
| RPS10 | ribosomal protein S10 | 0.0172707 |
| PTMA | prothymosin, alpha | 0.0170094 |
| HLA-B | major histocompatibility complex, class I, B | 0.0168775 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0166926 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0159835 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0157701 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0156354 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0154908 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0153828 |
| RPS23 | ribosomal protein S23 | 0.0152549 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0151024 |
| RPS25 | ribosomal protein S25 | 0.0149081 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0148474 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.014792 |
| RPL9 | ribosomal protein L9 | 0.014788 |
| PLEC | plectin | 0.0147871 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0147704 |
| RPLP1 | ribosomal protein, large, P1 | 0.014572 |
| USP36 | ubiquitin specific peptidase 36 | 0.0142243 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0140714 |
| HLA-A | major histocompatibility complex, class I, A | 0.0140554 |
| SPAG9 | sperm associated antigen 9 | 0.013996 |
| PUM1 | pumilio RNA-binding family member 1 | 0.01387 |
| LAMB3 | laminin, beta 3 | 0.013758 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0136213 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0135434 |
| B2M | beta-2-microglobulin | 0.0135244 |
| TFRC | transferrin receptor | 0.0134723 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0132807 |
| LRRC23 | leucine rich repeat containing 23 | 0.0131548 |
| RPS19 | ribosomal protein S19 | 0.0130951 |
| RCC1 | regulator of chromosome condensation 1 | 0.0127987 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0124077 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0123445 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0121729 |
| RPS11 | ribosomal protein S11 | 0.011699 |
| OGA | O-GlcNAcase | 0.0115885 |
| NABP1 | nucleic acid binding protein 1 | 0.0115762 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.011548 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0115177 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0114513 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.011417 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0113476 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0112453 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0112203 |
| IRS2 | insulin receptor substrate 2 | 0.0111243 |
| IER3 | immediate early response 3 | 0.011122 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0111051 |
| RPL34 | ribosomal protein L34 | 0.011084 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0110671 |
| S100A10 | S100 calcium binding protein A10 | 0.0109181 |
| RPS21 | ribosomal protein S21 | 0.0109101 |
| FLNA | filamin A, alpha | 0.0109044 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0107485 |
| GCNA | germ cell nuclear acidic peptidase | 0.010696 |
| ADM | adrenomedullin | 0.0106629 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0106153 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0105913 |
| PDE10A | phosphodiesterase 10A | 0.0105264 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0104958 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0104119 |
| FUS | FUS RNA binding protein | 0.0102871 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0102585 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0102386 |
| RPS13 | ribosomal protein S13 | 0.0101956 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0101234 |
| IRF1 | interferon regulatory factor 1 | 0.0100592 |
| SEC61G | Sec61 gamma subunit | 0.0097866 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00977998 |
| NAV2 | neuron navigator 2 | 0.00975355 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00973923 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.00964638 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.00961086 |
| MT2A | metallothionein 2A | 0.0095725 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00956245 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0095524 |
| IGF2 | insulin-like growth factor 2 | 0.00952847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.243547 |
| VIM | vimentin | -0.187199 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.185794 |
| EFNA5 | ephrin-A5 | -0.176929 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.156574 |
| MMP12 | matrix metallopeptidase 12 | -0.141014 |
| DTNA | dystrobrevin, alpha | -0.140657 |
| EXT1 | exostosin glycosyltransferase 1 | -0.132599 |
| GPC6 | glypican 6 | -0.132566 |
| ASPH | aspartate beta-hydroxylase | -0.12821 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.123898 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.111693 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.106589 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.104673 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.102489 |
| LSAMP | limbic system-associated membrane protein | -0.0982566 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0945801 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0895763 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0871653 |
| CDH13 | cadherin 13 | -0.0790268 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0777908 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0764206 |
| KIAA1217 | KIAA1217 | -0.0746145 |
| KIAA1549L | KIAA1549-like | -0.0721177 |
| CDK6 | cyclin-dependent kinase 6 | -0.0692501 |
| LDHA | lactate dehydrogenase A | -0.0652033 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0647522 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.064533 |
| RUNX1 | runt-related transcription factor 1 | -0.0635298 |
| NTM | neurotrimin | -0.0625413 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0623164 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0608332 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0607256 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0588564 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0571365 |
| ZNF804A | zinc finger protein 804A | -0.0565391 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0556273 |
| CALD1 | caldesmon 1 | -0.0544931 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.054152 |
| HMGA2 | high mobility group AT-hook 2 | -0.053823 |
| CDK14 | cyclin-dependent kinase 14 | -0.052549 |
| NAV1 | neuron navigator 1 | -0.0520803 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0510253 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0505851 |
| PKM | pyruvate kinase, muscle | -0.0490247 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0485504 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0478959 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0476193 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0471573 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0467027 |
| PTK2 | protein tyrosine kinase 2 | -0.0461959 |
| DST | dystonin | -0.0458559 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0445988 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0439486 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.043913 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0434305 |
| SBF2 | SET binding factor 2 | -0.0432399 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0430116 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0424207 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0409939 |
| LIMA1 | LIM domain and actin binding 1 | -0.0404063 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0403728 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0403252 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0398846 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0394916 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0381956 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0380723 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0375892 |
| MSR1 | macrophage scavenger receptor 1 | -0.0375174 |
| AHNAK | AHNAK nucleoprotein | -0.0374651 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0369379 |
| MSN | moesin | -0.0369186 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0368317 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0366284 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0360779 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.035744 |
| JMJD1C | jumonji domain containing 1C | -0.035378 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0352375 |
| CD109 | CD109 molecule | -0.0347665 |
| MAP1B | microtubule-associated protein 1B | -0.0345807 |
| MYO10 | myosin X | -0.034487 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.034308 |
| NRP2 | neuropilin 2 | -0.0341856 |
| ANO6 | anoctamin 6 | -0.0340227 |
| ITGA6 | integrin, alpha 6 | -0.034022 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0338559 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.033541 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0335239 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0332443 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0331678 |
| MAP4 | microtubule-associated protein 4 | -0.0331444 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0331003 |
| PRKCE | protein kinase C, epsilon | -0.0329808 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0329099 |
| RAI14 | retinoic acid induced 14 | -0.032868 |
| TXNRD1 | thioredoxin reductase 1 | -0.032786 |
| VCL | vinculin | -0.0326921 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0326648 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0324693 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0321592 |
