| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.0859343 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0848249 |
| PTMA | prothymosin, alpha | 0.0638594 |
| ONECUT3 | one cut homeobox 3 | 0.0628438 |
| LMO7 | LIM domain 7 | 0.0604294 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0525303 |
| AHNAK | AHNAK nucleoprotein | 0.0506345 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0489086 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0483566 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0483534 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0472001 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0449507 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0405572 |
| CTBP2 | C-terminal binding protein 2 | 0.0401847 |
| KRT18 | keratin 18, type I | 0.0396266 |
| RRBP1 | ribosome binding protein 1 | 0.039158 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0388409 |
| PRSS3 | protease, serine, 3 | 0.0382558 |
| SMYD3 | SET and MYND domain containing 3 | 0.0378007 |
| FOXO1 | forkhead box O1 | 0.0377546 |
| PLEC | plectin | 0.035309 |
| FERMT1 | fermitin family member 1 | 0.0351307 |
| AFDN | afadin, adherens junction formation factor | 0.0340868 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0334366 |
| OGA | O-GlcNAcase | 0.0326112 |
| RNF43 | ring finger protein 43 | 0.0324827 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0322433 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0315907 |
| ABHD17C | abhydrolase domain containing 17C | 0.0315553 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0315156 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0311497 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0307146 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0306508 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0306285 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0304426 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0298863 |
| HDAC2 | histone deacetylase 2 | 0.0294669 |
| IER3 | immediate early response 3 | 0.0287778 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0282768 |
| CD44 | CD44 molecule (Indian blood group) | 0.0270658 |
| S100A6 | S100 calcium binding protein A6 | 0.0268787 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0267732 |
| RBM25 | RNA binding motif protein 25 | 0.0262 |
| XPO1 | exportin 1 | 0.0260989 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0260101 |
| GAK | cyclin G associated kinase | 0.0255034 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.0254012 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0253205 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0252573 |
| LAMB3 | laminin, beta 3 | 0.0252208 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0250823 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0250755 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0249329 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0248803 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0248204 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0246723 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0244332 |
| TC2N | tandem C2 domains, nuclear | 0.0243647 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0243169 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0243148 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0241595 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0236636 |
| RNF145 | ring finger protein 145 | 0.0234964 |
| LMNA | lamin A/C | 0.0234649 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0232932 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0230282 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.0228995 |
| DUSP16 | dual specificity phosphatase 16 | 0.0227212 |
| TBC1D14 | TBC1 domain family, member 14 | 0.022714 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0227074 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0226693 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0225868 |
| SAFB2 | scaffold attachment factor B2 | 0.0225214 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0225196 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0222834 |
| RBM39 | RNA binding motif protein 39 | 0.0222475 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0221003 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0220914 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0220786 |
| H1-0 | H1.0 linker histone | 0.0220037 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0219524 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0218599 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0218401 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0217696 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0217345 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.021525 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0215108 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0214377 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0212404 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0210771 |
| RREB1 | ras responsive element binding protein 1 | 0.0210426 |
| APP | amyloid beta (A4) precursor protein | 0.021029 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0208557 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.020624 |
| H1-4 | H1.4 linker histone, cluster member | 0.0205342 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.020526 |
| AXIN2 | axin 2 | 0.0205219 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0204036 |
| EHBP1 | EH domain binding protein 1 | 0.0203352 |
| UBE3C | ubiquitin protein ligase E3C | 0.0203281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224169 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.192568 |
| VCL | vinculin | -0.146397 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.109878 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.106445 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.105686 |
| LDHA | lactate dehydrogenase A | -0.0914715 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0863755 |
| EZR | ezrin | -0.0795893 |
| VEGFA | vascular endothelial growth factor A | -0.0780041 |
| MYO1E | myosin IE | -0.0779996 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0726173 |
| RPS6 | ribosomal protein S6 | -0.0724282 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0691511 |
| PKM | pyruvate kinase, muscle | -0.0622135 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0621023 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.060212 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0593659 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0589966 |
| NDRG1 | N-myc downstream regulated 1 | -0.0555484 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0555298 |
| TRIM2 | tripartite motif containing 2 | -0.0520971 |
| PIGR | polymeric immunoglobulin receptor | -0.0492942 |
| TXNIP | thioredoxin interacting protein | -0.0492238 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.048411 |
| MUC17 | mucin 17, cell surface associated | -0.0482037 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.046399 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0461525 |
| FAT1 | FAT atypical cadherin 1 | -0.0458484 |
| POTEF | POTE ankyrin domain family, member F | -0.0448532 |
| PCBP2 | poly(rC) binding protein 2 | -0.0447862 |
| EGR1 | early growth response 1 | -0.0444549 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.044348 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0438723 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0434788 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0425161 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0417966 |
| PALLD | palladin, cytoskeletal associated protein | -0.0417479 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0407444 |
| CLDN4 | claudin 4 | -0.0400221 |
| VMP1 | vacuole membrane protein 1 | -0.0398885 |
| FOSL1 | FOS-like antigen 1 | -0.038861 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0386629 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0386442 |
| FTL | ferritin, light polypeptide | -0.0370793 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0364518 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0362075 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.036164 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0358536 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0354833 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0350703 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0350105 |
| RPL3 | ribosomal protein L3 | -0.0343764 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0343564 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0343371 |
| EMP1 | epithelial membrane protein 1 | -0.0342403 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0334873 |
| ABHD2 | abhydrolase domain containing 2 | -0.0331312 |
| ARF4 | ADP-ribosylation factor 4 | -0.032682 |
| MUC13 | mucin 13, cell surface associated | -0.0323053 |
| ANXA1 | annexin A1 | -0.0319347 |
| CALB1 | calbindin 1, 28kDa | -0.0313637 |
| INTS6 | integrator complex subunit 6 | -0.0310676 |
| RPS19 | ribosomal protein S19 | -0.0309415 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0302268 |
| AREG | amphiregulin | -0.0301669 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0297281 |
| TUFT1 | tuftelin 1 | -0.0296053 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0294028 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0293615 |
| MXD1 | MAX dimerization protein 1 | -0.0290806 |
| NDFIP2 | Nedd4 family interacting protein 2 | -0.0289326 |
| RPS8 | ribosomal protein S8 | -0.0287086 |
| DSPP | dentin sialophosphoprotein | -0.0285134 |
| RPS12 | ribosomal protein S12 | -0.0281553 |
| RPLP0 | ribosomal protein, large, P0 | -0.0279652 |
| DSTN | destrin (actin depolymerizing factor) | -0.0278178 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0278029 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0274281 |
| FHL2 | four and a half LIM domains 2 | -0.0273121 |
| FBXO11 | F-box protein 11 | -0.027199 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0264452 |
| GDF15 | growth differentiation factor 15 | -0.0264324 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0259614 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0259193 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.025757 |
| RPS23 | ribosomal protein S23 | -0.0256368 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0256298 |
| PFN1 | profilin 1 | -0.0255796 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0255496 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0254021 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | -0.0253325 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0252108 |
| ENO1 | enolase 1, (alpha) | -0.0251632 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0244745 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0242112 |
| RPL19 | ribosomal protein L19 | -0.024113 |
| RACK1 | receptor for activated C kinase 1 | -0.0240165 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0240065 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0237966 |
