| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0968016 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0869425 |
| POTEF | POTE ankyrin domain family, member F | 0.0727671 |
| CAPRIN2 | caprin family member 2 | 0.0716177 |
| INTS6 | integrator complex subunit 6 | 0.0591093 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0539548 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0516988 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515309 |
| CMIP | c-Maf inducing protein | 0.0485563 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0483682 |
| HOMER1 | homer scaffolding protein 1 | 0.0478925 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0454862 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0451209 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0440361 |
| RUNX1 | runt-related transcription factor 1 | 0.0413801 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0403106 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0398366 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0382169 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0380835 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0380258 |
| RCOR1 | REST corepressor 1 | 0.0380226 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0377842 |
| UBC | ubiquitin C | 0.037295 |
| TGM2 | transglutaminase 2 | 0.0365886 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0357143 |
| PCBP2 | poly(rC) binding protein 2 | 0.0355939 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0355611 |
| MCL1 | myeloid cell leukemia 1 | 0.0354674 |
| NEK10 | NIMA-related kinase 10 | 0.0343141 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0339309 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0337366 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0334967 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0334457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333778 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0333274 |
| USP12 | ubiquitin specific peptidase 12 | 0.0331489 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0317762 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0316559 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.031242 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0311539 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0308345 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0306499 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0305965 |
| DNER | delta/notch-like EGF repeat containing | 0.0299883 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0297907 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0291508 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0289868 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0286443 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0285275 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0283664 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0282901 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0281145 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.028104 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.027985 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.02794 |
| WDR27 | WD repeat domain 27 | 0.027891 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0275519 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274862 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0267143 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.0266249 |
| MB21D2 | Mab-21 domain containing 2 | 0.0256611 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.025582 |
| HMGA1 | high mobility group AT-hook 1 | 0.0252827 |
| CORO1C | coronin, actin binding protein, 1C | 0.0250646 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0248992 |
| ZNF638 | zinc finger protein 638 | 0.0248021 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0247505 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0246824 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0244229 |
| RPL23 | ribosomal protein L23 | 0.0243693 |
| CTBP2 | C-terminal binding protein 2 | 0.0241086 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.024011 |
| SMAD3 | SMAD family member 3 | 0.0239954 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.02383 |
| ACTN1 | actinin, alpha 1 | 0.0236293 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0235107 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0234519 |
| SKI | SKI proto-oncogene | 0.0233382 |
| AEBP2 | AE binding protein 2 | 0.0232415 |
| NAV2 | neuron navigator 2 | 0.0227672 |
| RPS12 | ribosomal protein S12 | 0.022205 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0220404 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0219999 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.021814 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0217719 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0216127 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0211006 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.021071 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0208233 |
| SP100 | SP100 nuclear antigen | 0.0201887 |
| VEGFC | vascular endothelial growth factor C | 0.0198955 |
| ABR | active BCR-related | 0.0195948 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0195439 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0195422 |
| ACTN4 | actinin, alpha 4 | 0.0190508 |
| HDAC4 | histone deacetylase 4 | 0.0188214 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0188049 |
| ZNF644 | zinc finger protein 644 | 0.0184426 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0184023 |
| TBCD | tubulin folding cofactor D | 0.0183179 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177124 |
| PTMA | prothymosin, alpha | -0.155222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.1363 |
| MT2A | metallothionein 2A | -0.106447 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.105588 |
| TMSB4X | thymosin beta 4, X-linked | -0.0905654 |
| TP63 | tumor protein p63 | -0.0814228 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0788 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0704465 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0692181 |
| PGK1 | phosphoglycerate kinase 1 | -0.0663477 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0654792 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0611586 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.060859 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.059578 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0583726 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0570571 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0549985 |
| RIGI | RNA sensor RIG-I | -0.0524613 |
| CANX | calnexin | -0.0503232 |
| SDC4 | syndecan 4 | -0.0496981 |
| H1-0 | H1.0 linker histone | -0.0481691 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0465271 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0460338 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0457121 |
| EHBP1 | EH domain binding protein 1 | -0.0436432 |
| RAI1 | retinoic acid induced 1 | -0.0429264 |
| RLF | rearranged L-myc fusion | -0.042699 |
| FTL | ferritin, light polypeptide | -0.0394059 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0391192 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0388186 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0380334 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0375009 |
| SPAG9 | sperm associated antigen 9 | -0.0373875 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.037225 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0367991 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0367195 |
| EREG | epiregulin | -0.0364379 |
| DOCK11 | dedicator of cytokinesis 11 | -0.0363321 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0360539 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0351578 |
| ANXA1 | annexin A1 | -0.0350484 |
| APP | amyloid beta (A4) precursor protein | -0.0346414 |
| MATR3 | matrin 3 | -0.0339159 |
| MT1E | metallothionein 1E | -0.0339027 |
| SMYD3 | SET and MYND domain containing 3 | -0.0337534 |
| ZNF292 | zinc finger protein 292 | -0.0334491 |
| NEMF | nuclear export mediator factor | -0.0334024 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0330604 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0328327 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.032753 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0324335 |
| HLA-B | major histocompatibility complex, class I, B | -0.0322444 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0321393 |
| OGA | O-GlcNAcase | -0.0320119 |
| TUBB | tubulin, beta class I | -0.0319709 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0319499 |
| CALR | calreticulin | -0.0315157 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0310526 |
| ZFR | zinc finger RNA binding protein | -0.0309684 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0309052 |
| WDR45B | WD repeat domain 45B | -0.0307967 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0306732 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0306418 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0305056 |
| CD44 | CD44 molecule (Indian blood group) | -0.0304896 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0304371 |
| LDHA | lactate dehydrogenase A | -0.0303611 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0301608 |
| EZR | ezrin | -0.0300767 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0299886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0298909 |
| RPL35A | ribosomal protein L35a | -0.0298676 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0297789 |
| TRIM56 | tripartite motif containing 56 | -0.029693 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0290415 |
| GOLGA4 | golgin A4 | -0.0288043 |
| RAD50 | RAD50 homolog (S. cerevisiae) | -0.0284011 |
| RBM25 | RNA binding motif protein 25 | -0.0282908 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0280283 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0279543 |
| ACTG1 | actin gamma 1 | -0.0277537 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0276413 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.027427 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0273338 |
| THOC2 | THO complex 2 | -0.0269458 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0268892 |
| ZNF217 | zinc finger protein 217 | -0.0267788 |
| RPS24 | ribosomal protein S24 | -0.0267377 |
| SBF2 | SET binding factor 2 | -0.0264954 |
| RAD21 | RAD21 homolog (S. pombe) | -0.026457 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.026426 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0260555 |
| MKI67 | marker of proliferation Ki-67 | -0.0260266 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0255518 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0253439 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0253389 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0253217 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0253073 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0252648 |
