| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.179014 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0627446 |
| GRAMD1B | GRAM domain containing 1B | 0.052845 |
| MT2A | metallothionein 2A | 0.0458703 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0405198 |
| NABP1 | nucleic acid binding protein 1 | 0.0361153 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0358796 |
| TBC1D22A | TBC1 domain family, member 22A | 0.031584 |
| INTS6 | integrator complex subunit 6 | 0.0312296 |
| MCL1 | myeloid cell leukemia 1 | 0.0306483 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0283754 |
| CCNL1 | cyclin L1 | 0.027334 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0253363 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.023553 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0213714 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0211631 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0202129 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0198257 |
| CUL4A | cullin 4A | 0.0195514 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0195241 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.018896 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0186739 |
| RAD51B | RAD51 paralog B | 0.018619 |
| GPATCH2L | G patch domain containing 2-like | 0.0183158 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0182306 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0174586 |
| WDR26 | WD repeat domain 26 | 0.0168952 |
| GPHN | gephyrin | 0.0166852 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0166661 |
| TUFT1 | tuftelin 1 | 0.0165858 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0165528 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0163332 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0158576 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0155747 |
| ANKRD12 | ankyrin repeat domain 12 | 0.015426 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0151932 |
| BMP6 | bone morphogenetic protein 6 | 0.0149572 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0146589 |
| HOMER1 | homer scaffolding protein 1 | 0.0145688 |
| SMYD3 | SET and MYND domain containing 3 | 0.0145097 |
| PLEC | plectin | 0.014508 |
| ZNF638 | zinc finger protein 638 | 0.0144246 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0143412 |
| RUNX1 | runt-related transcription factor 1 | 0.0143065 |
| SLTM | SAFB-like, transcription modulator | 0.0141156 |
| RTN4 | reticulon 4 | 0.0135802 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0135019 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0134983 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0134785 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0132906 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0132455 |
| HDAC4 | histone deacetylase 4 | 0.0132097 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0130762 |
| PRKCE | protein kinase C, epsilon | 0.0129321 |
| VMP1 | vacuole membrane protein 1 | 0.0128506 |
| MYOF | myoferlin | 0.0127993 |
| KIAA1328 | KIAA1328 | 0.0127627 |
| WWOX | WW domain containing oxidoreductase | 0.0127268 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0126948 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.012651 |
| SMAD3 | SMAD family member 3 | 0.0125004 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0124129 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0121934 |
| METTL15 | methyltransferase like 15 | 0.0117745 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0117278 |
| USP34 | ubiquitin specific peptidase 34 | 0.0117193 |
| FUS | FUS RNA binding protein | 0.0115131 |
| PRELID2 | PRELI domain containing 2 | 0.0113471 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.011318 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0112558 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0112306 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0110469 |
| SETX | senataxin | 0.0110468 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0106785 |
| FHL2 | four and a half LIM domains 2 | 0.010616 |
| SKIL | SKI-like proto-oncogene | 0.0105738 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0105567 |
| HDAC8 | histone deacetylase 8 | 0.0105064 |
| WDR1 | WD repeat domain 1 | 0.010417 |
| TBCA | tubulin folding cofactor A | 0.0104035 |
| CTTN | cortactin | 0.0103982 |
| ATP11A | ATPase, class VI, type 11A | 0.0103594 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.010262 |
| EVI5 | ecotropic viral integration site 5 | 0.0101335 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0101171 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0100786 |
| FNIP1 | folliculin interacting protein 1 | 0.0100457 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.00995642 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.00984132 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00982921 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00975335 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00975117 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.00971732 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00954528 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00953927 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00951608 |
| USO1 | USO1 vesicle transport factor | 0.00950031 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00935149 |
| SUMF1 | sulfatase modifying factor 1 | 0.0092976 |
| DST | dystonin | 0.00921035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.276182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.219025 |
| TMSB10 | thymosin beta 10 | -0.140783 |
| ASPH | aspartate beta-hydroxylase | -0.127888 |
| LMO7 | LIM domain 7 | -0.116947 |
| FAM13A | family with sequence similarity 13, member A | -0.0967802 |
| PTMA | prothymosin, alpha | -0.0930824 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0897202 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0846364 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0841281 |
| PKM | pyruvate kinase, muscle | -0.0762846 |
| NDRG1 | N-myc downstream regulated 1 | -0.0718444 |
| LDHA | lactate dehydrogenase A | -0.0695049 |
| H1-0 | H1.0 linker histone | -0.0692324 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.069175 |
| PGK1 | phosphoglycerate kinase 1 | -0.0682027 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0674367 |
| ACTG1 | actin gamma 1 | -0.0669513 |
| ANXA2 | annexin A2 | -0.0651683 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0610481 |
| ENO1 | enolase 1, (alpha) | -0.0605149 |
| SEC61G | Sec61 gamma subunit | -0.0598101 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0582906 |
| S100A10 | S100 calcium binding protein A10 | -0.0579927 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0573181 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0563387 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0536112 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.052895 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0527582 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0517141 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0508668 |
| PDE8A | phosphodiesterase 8A | -0.0490986 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.046672 |
| FTL | ferritin, light polypeptide | -0.045291 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0452666 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0450847 |
| LAMC2 | laminin, gamma 2 | -0.0450323 |
| TMEM165 | transmembrane protein 165 | -0.0446192 |
| STC1 | stanniocalcin 1 | -0.0440572 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0436928 |
| HDLBP | high density lipoprotein binding protein | -0.0432941 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0432783 |
| RNF145 | ring finger protein 145 | -0.0425001 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0418886 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0410919 |
| KRT18 | keratin 18, type I | -0.0410814 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0405298 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0397204 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0395812 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.03933 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0387909 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0386814 |
| UVRAG | UV radiation resistance associated | -0.038523 |
| TPD52 | tumor protein D52 | -0.0371667 |
| EGR1 | early growth response 1 | -0.0370884 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0370353 |
| LAMA4 | laminin, alpha 4 | -0.0361747 |
| SPAG9 | sperm associated antigen 9 | -0.0359078 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0346314 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0346037 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.034548 |
| TES | testin LIM domain protein | -0.0343871 |
| ARRDC3 | arrestin domain containing 3 | -0.0337198 |
| WDR45B | WD repeat domain 45B | -0.033123 |
| DSPP | dentin sialophosphoprotein | -0.0329814 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0329561 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0327863 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0314285 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0313322 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.031213 |
| UBC | ubiquitin C | -0.0309523 |
| S100A6 | S100 calcium binding protein A6 | -0.0309376 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0307601 |
| CST3 | cystatin C | -0.0304432 |
| WASF2 | WAS protein family, member 2 | -0.0304003 |
| RAB10 | RAB10, member RAS oncogene family | -0.0301721 |
| MXI1 | MAX interactor 1, dimerization protein | -0.030076 |
| TXNRD1 | thioredoxin reductase 1 | -0.0298375 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0297992 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0295814 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0295658 |
| USP3 | ubiquitin specific peptidase 3 | -0.029564 |
| CPE | carboxypeptidase E | -0.0294162 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0288903 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0288061 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0285463 |
| SLMAP | sarcolemma associated protein | -0.0282447 |
| CANX | calnexin | -0.028091 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.027152 |
| ATP13A3 | ATPase type 13A3 | -0.027135 |
| AHNAK | AHNAK nucleoprotein | -0.0268604 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0268311 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0267599 |
| OGA | O-GlcNAcase | -0.0265687 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0265469 |
| NGLY1 | N-glycanase 1 | -0.0264763 |
| LAMB3 | laminin, beta 3 | -0.0264709 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0262743 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0258729 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0255862 |
