| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM20C | family with sequence similarity 20, member C | 0.077069 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0766295 |
| SMAD3 | SMAD family member 3 | 0.0648331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0618053 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0464069 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0462139 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0327704 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0317118 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0317004 |
| MT2A | metallothionein 2A | 0.0306024 |
| GLCCI1 | glucocorticoid induced 1 | 0.0275813 |
| KSR1 | kinase suppressor of ras 1 | 0.0275168 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0261483 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0260092 |
| INTS6 | integrator complex subunit 6 | 0.0258811 |
| NTN4 | netrin 4 | 0.021634 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0214467 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0212725 |
| RBM39 | RNA binding motif protein 39 | 0.0209938 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0203345 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0203299 |
| OGA | O-GlcNAcase | 0.0196576 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196083 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0191992 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0190007 |
| MEIS1 | Meis homeobox 1 | 0.0188423 |
| HDAC4 | histone deacetylase 4 | 0.0186187 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0185601 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0183791 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0174135 |
| HDLBP | high density lipoprotein binding protein | 0.0169026 |
| NABP1 | nucleic acid binding protein 1 | 0.0163295 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0151672 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0146378 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0144013 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0140929 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0136235 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0135078 |
| EFNA5 | ephrin-A5 | 0.0134647 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0134277 |
| FLNA | filamin A, alpha | 0.0134071 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0132186 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0131701 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0131578 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0131161 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0130457 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0129617 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0129317 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0129067 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0127943 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0127584 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0127241 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.0126769 |
| STK38L | serine/threonine kinase 38 like | 0.0126577 |
| MICALL2 | MICAL-like 2 | 0.01263 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0126299 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.0126217 |
| HEATR5A | HEAT repeat containing 5A | 0.0126065 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0125393 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0124705 |
| ZNF385D | zinc finger protein 385D | 0.0124285 |
| MYO10 | myosin X | 0.0122133 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0121841 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0118989 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0117837 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.011721 |
| SMYD3 | SET and MYND domain containing 3 | 0.0116063 |
| GOLGA3 | golgin A3 | 0.0115797 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0113851 |
| RUNX1 | runt-related transcription factor 1 | 0.0110452 |
| CPNE1 | copine I | 0.0109551 |
| CAPRIN2 | caprin family member 2 | 0.0108582 |
| RPL32 | ribosomal protein L32 | 0.0105728 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0105205 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | 0.0105045 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0103871 |
| FRMD5 | FERM domain containing 5 | 0.0103345 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0103258 |
| HTRA3 | HtrA serine peptidase 3 | 0.010276 |
| GSE1 | Gse1 coiled-coil protein | 0.0102494 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0101685 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0101118 |
| TASOR2 | transcription activation suppressor family member 2 | 0.00999144 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00995336 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00994397 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.00989167 |
| CHLSN | cholesin | 0.0098272 |
| ACTN4 | actinin, alpha 4 | 0.00976413 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.00966891 |
| AVIL | advillin | 0.0096288 |
| BLCAP | bladder cancer associated protein | 0.00961702 |
| GPHN | gephyrin | 0.00956904 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.00956632 |
| RPS21 | ribosomal protein S21 | 0.00949895 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.00946299 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00945874 |
| YBX3 | Y box binding protein 3 | 0.00943082 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00939561 |
| ANKRD36C | ankyrin repeat domain 36C | 0.00933668 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00933248 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.214696 |
| VIM | vimentin | -0.146039 |
| FN1 | fibronectin 1 | -0.137873 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.113215 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0957086 |
| LOX | lysyl oxidase | -0.0955307 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0884881 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0871187 |
| MEF2A | myocyte enhancer factor 2A | -0.0865838 |
| STC1 | stanniocalcin 1 | -0.0797224 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0771691 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.074442 |
| TMSB10 | thymosin beta 10 | -0.073716 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0726506 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0695285 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0670697 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0668126 |
| NDRG1 | N-myc downstream regulated 1 | -0.0661479 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0607862 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0599204 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0549585 |
| ENO1 | enolase 1, (alpha) | -0.0520609 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0518292 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0498006 |
| S100A6 | S100 calcium binding protein A6 | -0.0492086 |
| USP34 | ubiquitin specific peptidase 34 | -0.0491146 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0489034 |
| CA12 | carbonic anhydrase XII | -0.0487322 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0477352 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0457717 |
| FAM13A | family with sequence similarity 13, member A | -0.0456476 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456325 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0440096 |
| CDCP1 | CUB domain containing protein 1 | -0.0439485 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0437136 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437001 |
| EGR1 | early growth response 1 | -0.0432188 |
| RAI14 | retinoic acid induced 14 | -0.0429244 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0428539 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0428133 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0428005 |
| MTSS1 | metastasis suppressor 1 | -0.0424044 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0422943 |
| GOLGA4 | golgin A4 | -0.0422581 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0417009 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0414336 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0409168 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0399998 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0392868 |
| B2M | beta-2-microglobulin | -0.0391674 |
| LDHA | lactate dehydrogenase A | -0.0387854 |
| NRG1 | neuregulin 1 | -0.0379772 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0376045 |
| CDH13 | cadherin 13 | -0.0375231 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0368152 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0366131 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0349611 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0334178 |
| PKM | pyruvate kinase, muscle | -0.0334025 |
| POTEF | POTE ankyrin domain family, member F | -0.0333817 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0333419 |
| CCDC88A | coiled-coil domain containing 88A | -0.0328733 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.032763 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0324021 |
| PYGL | phosphorylase, glycogen, liver | -0.0319105 |
| PLIN2 | perilipin 2 | -0.0316162 |
| FTL | ferritin, light polypeptide | -0.0313639 |
| RIOK3 | RIO kinase 3 | -0.0303513 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302631 |
| ANGPTL4 | angiopoietin-like 4 | -0.0301383 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0295491 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0293995 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0291748 |
| HMGA2 | high mobility group AT-hook 2 | -0.0290722 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0289781 |
| HMGA1 | high mobility group AT-hook 1 | -0.0286937 |
| PCBP2 | poly(rC) binding protein 2 | -0.028639 |
| MYADM | myeloid-associated differentiation marker | -0.0285235 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0284977 |
| CLMP | CXADR-like membrane protein | -0.0281529 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0280729 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0278123 |
| DTNA | dystrobrevin, alpha | -0.0277479 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0275284 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0275151 |
| DST | dystonin | -0.0274649 |
| VEGFA | vascular endothelial growth factor A | -0.027456 |
| OXR1 | oxidation resistance 1 | -0.0273743 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0273656 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0272421 |
| OSMR | oncostatin M receptor | -0.0269636 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0264712 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0263506 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.026246 |
| JMJD1C | jumonji domain containing 1C | -0.026094 |
| TMEM165 | transmembrane protein 165 | -0.0258931 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0257654 |
| TMSB4X | thymosin beta 4, X-linked | -0.0256546 |
| MAP1B | microtubule-associated protein 1B | -0.0254018 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0252798 |