| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.0947865 |
| TXNRD1 | thioredoxin reductase 1 | 0.0821718 |
| GRAMD1B | GRAM domain containing 1B | 0.0745736 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0715056 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0676288 |
| AHNAK | AHNAK nucleoprotein | 0.0530946 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0491745 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0476738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.044222 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0429448 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419619 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0409013 |
| WWOX | WW domain containing oxidoreductase | 0.0382445 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0380331 |
| ASPH | aspartate beta-hydroxylase | 0.0375866 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0366361 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0365224 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0359518 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314286 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0285805 |
| APP | amyloid beta (A4) precursor protein | 0.0280477 |
| RPL4 | ribosomal protein L4 | 0.0273573 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0270374 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0265255 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0261249 |
| IGF1R | insulin-like growth factor 1 receptor | 0.024729 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0245553 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0232622 |
| BICC1 | BicC family RNA binding protein 1 | 0.0231699 |
| AHR | aryl hydrocarbon receptor | 0.0228078 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0217411 |
| CANX | calnexin | 0.0209005 |
| RRM2 | ribonucleotide reductase M2 | 0.0196532 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0190684 |
| KYNU | kynureninase | 0.0188926 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0187867 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0183373 |
| CAVIN1 | caveolae associated protein 1 | 0.0178884 |
| ECT2 | epithelial cell transforming 2 | 0.01765 |
| PLEC | plectin | 0.0175355 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0174584 |
| HDLBP | high density lipoprotein binding protein | 0.0173293 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0171446 |
| H1-2 | H1.2 linker histone, cluster member | 0.0170249 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0169888 |
| RHEB | Ras homolog enriched in brain | 0.0166056 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0165475 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0162451 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0161733 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0161601 |
| HMGB2 | high mobility group box 2 | 0.0160431 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0159153 |
| EFNA5 | ephrin-A5 | 0.0158409 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0154001 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0152586 |
| ANLN | anillin, actin binding protein | 0.0152418 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0152234 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0151395 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0148369 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0148164 |
| HYOU1 | hypoxia up-regulated 1 | 0.0147963 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0145994 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0145572 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0145306 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0143735 |
| MKI67 | marker of proliferation Ki-67 | 0.0141625 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0141376 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.014042 |
| RPL6 | ribosomal protein L6 | 0.0140336 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139416 |
| DST | dystonin | 0.0139277 |
| FGG | fibrinogen gamma chain | 0.013879 |
| FUS | FUS RNA binding protein | 0.0138074 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0137822 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.013579 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0135687 |
| RPL19 | ribosomal protein L19 | 0.0135236 |
| SMAD2 | SMAD family member 2 | 0.0134482 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0133371 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0133014 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0132697 |
| IPO7 | importin 7 | 0.0130622 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0130299 |
| ANXA2 | annexin A2 | 0.0129286 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0129075 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0128248 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0127436 |
| POU2F1 | POU class 2 homeobox 1 | 0.012734 |
| RBM33 | RNA binding motif protein 33 | 0.0126606 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0126556 |
| H1-0 | H1.0 linker histone | 0.012642 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0126046 |
| TMEM123 | transmembrane protein 123 | 0.0125477 |
| RPL41 | ribosomal protein L41 | 0.0124471 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0124335 |
| ILF2 | interleukin enhancer binding factor 2 | 0.0123414 |
| TFRC | transferrin receptor | 0.0123225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0122865 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0122539 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0122097 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.347925 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.193144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11546 |
| IGF2 | insulin-like growth factor 2 | -0.103308 |
| VIM | vimentin | -0.0921879 |
| TMSB10 | thymosin beta 10 | -0.0769683 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0751456 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0691269 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0625789 |
| S100A6 | S100 calcium binding protein A6 | -0.0618329 |
| FMNL2 | formin-like 2 | -0.0579234 |
| PYGL | phosphorylase, glycogen, liver | -0.0555331 |
| RBM25 | RNA binding motif protein 25 | -0.0552453 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.054125 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0513663 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0512563 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507918 |
| HLA-B | major histocompatibility complex, class I, B | -0.0494272 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0472671 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0470136 |
| FLNB | filamin B, beta | -0.0461207 |
| COPA | coatomer protein complex, subunit alpha | -0.0458436 |
| POTEF | POTE ankyrin domain family, member F | -0.0437751 |
| IL6 | interleukin 6 | -0.0432234 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0422246 |
| ZNF207 | zinc finger protein 207 | -0.0408104 |
| GOLGA4 | golgin A4 | -0.0385777 |
| HLA-A | major histocompatibility complex, class I, A | -0.0383332 |
| PFN1 | profilin 1 | -0.0365573 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0355469 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0337507 |
| ERBIN | erbb2 interacting protein | -0.0334288 |
| ACTG1 | actin gamma 1 | -0.033035 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0329947 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0323248 |
| RPL37A | ribosomal protein L37a | -0.0320135 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0319933 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0316964 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0316284 |
| NEMF | nuclear export mediator factor | -0.0303123 |
| CMIP | c-Maf inducing protein | -0.0302802 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0300755 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.029565 |
| RPL35A | ribosomal protein L35a | -0.029404 |
| NOP58 | NOP58 ribonucleoprotein | -0.0293231 |
| RPS6 | ribosomal protein S6 | -0.0292384 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0291378 |
| HMGA1 | high mobility group AT-hook 1 | -0.0291155 |
| TPM4 | tropomyosin 4 | -0.0283274 |
| HM13 | histocompatibility (minor) 13 | -0.0280249 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0280132 |
| ACTN1 | actinin, alpha 1 | -0.0275875 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0274049 |
| SNX14 | sorting nexin 14 | -0.0272495 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0269904 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0268945 |
| EGFR | epidermal growth factor receptor | -0.02676 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0265127 |
| RPL31 | ribosomal protein L31 | -0.0264202 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0262211 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0261953 |
| SRP54 | signal recognition particle 54kDa | -0.0260017 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0257358 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0255502 |
| MYADM | myeloid-associated differentiation marker | -0.0255458 |
| EGR1 | early growth response 1 | -0.0253588 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.025317 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0252178 |
| RPL9 | ribosomal protein L9 | -0.02505 |
| HDGF | hepatoma-derived growth factor | -0.0249544 |
| ITGB5 | integrin, beta 5 | -0.0245611 |
| GLG1 | golgi glycoprotein 1 | -0.0240162 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0239098 |
| PDE8A | phosphodiesterase 8A | -0.023825 |
| TMEM87A | transmembrane protein 87A | -0.0236936 |
| ARF4 | ADP-ribosylation factor 4 | -0.0236805 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0236262 |
| SBF2 | SET binding factor 2 | -0.0234527 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0234347 |
| SLMAP | sarcolemma associated protein | -0.0232429 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0231447 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0229979 |
| RPS12 | ribosomal protein S12 | -0.0229248 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0229207 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0228631 |
| LDHA | lactate dehydrogenase A | -0.0228472 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0228415 |
| IER3 | immediate early response 3 | -0.0227971 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0227916 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0226151 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0225956 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0224632 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0223533 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.022322 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0221569 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0221417 |
| CFDP1 | craniofacial development protein 1 | -0.0221048 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0220825 |
| RSF1 | remodeling and spacing factor 1 | -0.0220452 |
| CCNL1 | cyclin L1 | -0.021879 |
