| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.146955 |
| TXNRD1 | thioredoxin reductase 1 | 0.136249 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0645539 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0629773 |
| OGA | O-GlcNAcase | 0.0545776 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0482742 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0421702 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0420019 |
| RTN4 | reticulon 4 | 0.0405627 |
| PHIP | pleckstrin homology domain interacting protein | 0.0392676 |
| XPO1 | exportin 1 | 0.0368443 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.035325 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328761 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0317926 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0317324 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0308298 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0300836 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0300409 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0288404 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275285 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0273509 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0271278 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0262368 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0259212 |
| PCBP2 | poly(rC) binding protein 2 | 0.0257275 |
| ERBIN | erbb2 interacting protein | 0.0249255 |
| IPO7 | importin 7 | 0.0248529 |
| SPAG9 | sperm associated antigen 9 | 0.024402 |
| FUS | FUS RNA binding protein | 0.024335 |
| NUP153 | nucleoporin 153kDa | 0.0243205 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240043 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0235473 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0230079 |
| CLTC | clathrin, heavy chain (Hc) | 0.0229609 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.022882 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0227851 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0224439 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0224207 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0221783 |
| CTTN | cortactin | 0.0216185 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0215771 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0215356 |
| STK4 | serine/threonine kinase 4 | 0.020735 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0205958 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0205195 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0203958 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0202426 |
| NCKAP1 | NCK-associated protein 1 | 0.0202326 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0201842 |
| RRM2 | ribonucleotide reductase M2 | 0.0201457 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0200574 |
| TJP1 | tight junction protein 1 | 0.0197641 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0196111 |
| MATR3 | matrin 3 | 0.0195909 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0192371 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0191931 |
| PCNX1 | pecanex 1 | 0.019114 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0190472 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0189264 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0188424 |
| PGK1 | phosphoglycerate kinase 1 | 0.0188182 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0187315 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0186728 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0186331 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0182385 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0182167 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0181594 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0180969 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0180953 |
| GPHN | gephyrin | 0.0180816 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0180625 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0179291 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0178614 |
| PLCB4 | phospholipase C, beta 4 | 0.0178005 |
| SRPK2 | SRSF protein kinase 2 | 0.0177312 |
| TFG | TRK-fused gene | 0.0176213 |
| MKI67 | marker of proliferation Ki-67 | 0.0175609 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0175458 |
| UBC | ubiquitin C | 0.017378 |
| SEPTIN2 | septin 2 | 0.0173032 |
| RNF145 | ring finger protein 145 | 0.0170735 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0169909 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.016867 |
| CCNT1 | cyclin T1 | 0.016784 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.016686 |
| PER1 | period circadian clock 1 | 0.0166703 |
| PLEC | plectin | 0.0164907 |
| ADAR | adenosine deaminase, RNA-specific | 0.0164109 |
| TMPO | thymopoietin | 0.0163712 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0162811 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0161588 |
| ETV3 | ets variant 3 | 0.016152 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0161469 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0161017 |
| NEK7 | NIMA-related kinase 7 | 0.0160637 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.016048 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0159371 |
| RLF | rearranged L-myc fusion | 0.0159247 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0158883 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0158708 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.403035 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.19225 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.102339 |
| YBX3 | Y box binding protein 3 | -0.0996219 |
| TMSB10 | thymosin beta 10 | -0.0952839 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.093715 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0914298 |
| RAD51B | RAD51 paralog B | -0.0859135 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0857982 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0763151 |
| HMGA2 | high mobility group AT-hook 2 | -0.0746562 |
| ATXN1 | ataxin 1 | -0.0738915 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0681328 |
| OSMR | oncostatin M receptor | -0.0665331 |
| PDE10A | phosphodiesterase 10A | -0.0653626 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0631704 |
| RPS3 | ribosomal protein S3 | -0.0631149 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0628632 |
| HLA-B | major histocompatibility complex, class I, B | -0.0623509 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0617903 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0617085 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0606675 |
| MT2A | metallothionein 2A | -0.0593945 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0584041 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0575794 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.055386 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0530386 |
| PTMA | prothymosin, alpha | -0.0510359 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0497565 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0489987 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0483701 |
| POTEF | POTE ankyrin domain family, member F | -0.0482657 |
| EGFR | epidermal growth factor receptor | -0.0479222 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0477291 |
| RPL37A | ribosomal protein L37a | -0.0475103 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0469012 |
| RYR3 | ryanodine receptor 3 | -0.0465797 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0457609 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0448881 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0445088 |
| EXOC4 | exocyst complex component 4 | -0.0443847 |
| MCL1 | myeloid cell leukemia 1 | -0.0442501 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0412725 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0404698 |
| RNF213 | ring finger protein 213 | -0.0400506 |
| RPL37 | ribosomal protein L37 | -0.0394138 |
| ACTG1 | actin gamma 1 | -0.0384429 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0375739 |
| AEBP2 | AE binding protein 2 | -0.0371847 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0358967 |
| PYGL | phosphorylase, glycogen, liver | -0.0355633 |
| FMNL2 | formin-like 2 | -0.0354983 |
| NF1 | neurofibromin 1 | -0.034911 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0343312 |
| GRAMD1B | GRAM domain containing 1B | -0.0340878 |
| EHBP1 | EH domain binding protein 1 | -0.0340326 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0337827 |
| CUX1 | cut-like homeobox 1 | -0.0336143 |
| RPS19 | ribosomal protein S19 | -0.0336053 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0333874 |
| WWOX | WW domain containing oxidoreductase | -0.0329769 |
| DENND5B | DENN/MADD domain containing 5B | -0.0328398 |
| RPS12 | ribosomal protein S12 | -0.0325847 |
| ATG7 | autophagy related 7 | -0.0325722 |
| TPM2 | tropomyosin 2 (beta) | -0.0324829 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0319664 |
| VCL | vinculin | -0.0317565 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.03151 |
| NLGN1 | neuroligin 1 | -0.0314623 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0314071 |
| DIAPH2 | diaphanous-related formin 2 | -0.0313684 |
| LOXL2 | lysyl oxidase-like 2 | -0.0313075 |
| CCDC91 | coiled-coil domain containing 91 | -0.0311526 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0307854 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0304742 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0303757 |
| PTK2 | protein tyrosine kinase 2 | -0.0298407 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0292004 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0291059 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0291003 |
| VIM | vimentin | -0.0290809 |
| USP34 | ubiquitin specific peptidase 34 | -0.0288192 |
| SVIL | supervillin | -0.0285372 |
| PRELID2 | PRELI domain containing 2 | -0.0281606 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0281318 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0278854 |
| RSF1 | remodeling and spacing factor 1 | -0.0275028 |
| EGR1 | early growth response 1 | -0.0272747 |
| RPL26 | ribosomal protein L26 | -0.0272053 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0269422 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0267857 |
| RPL36 | ribosomal protein L36 | -0.0267425 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0265943 |
| TRIM9 | tripartite motif containing 9 | -0.0265157 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0264495 |
| IGF2 | insulin-like growth factor 2 | -0.0264185 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0262652 |
| RPL31 | ribosomal protein L31 | -0.0261491 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0258027 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0256941 |
