| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.217397 |
| LAMC2 | laminin, gamma 2 | 0.0895528 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0795811 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0777961 |
| LMO7 | LIM domain 7 | 0.076289 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0760652 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0726739 |
| ASPH | aspartate beta-hydroxylase | 0.0712191 |
| HMGB2 | high mobility group box 2 | 0.068686 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0579412 |
| AHNAK | AHNAK nucleoprotein | 0.0541382 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0533809 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0531645 |
| LAMB3 | laminin, beta 3 | 0.0527784 |
| PTMA | prothymosin, alpha | 0.0452447 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0448337 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0442116 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0425175 |
| CCND1 | cyclin D1 | 0.0405322 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0402663 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0400952 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0389322 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0341537 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0334224 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0331203 |
| ANXA2 | annexin A2 | 0.0325822 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.03228 |
| PLEC | plectin | 0.0318586 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0315849 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0299872 |
| KRT7 | keratin 7, type II | 0.0284889 |
| SDC4 | syndecan 4 | 0.028121 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0276706 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.026657 |
| KLF6 | Kruppel-like factor 6 | 0.0263204 |
| CAVIN1 | caveolae associated protein 1 | 0.0257419 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0253436 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0250909 |
| LMNA | lamin A/C | 0.024446 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0244149 |
| RPS24 | ribosomal protein S24 | 0.0235191 |
| CD2AP | CD2-associated protein | 0.0234402 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0231685 |
| APP | amyloid beta (A4) precursor protein | 0.02289 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0227715 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0227549 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0224827 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0223846 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0222452 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0222201 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0219448 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.021895 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0214664 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0211215 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0209226 |
| ANLN | anillin, actin binding protein | 0.0204807 |
| RPL6 | ribosomal protein L6 | 0.0203534 |
| SVIL | supervillin | 0.0203025 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0200816 |
| TMSB4X | thymosin beta 4, X-linked | 0.020034 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0198141 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0197831 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0193121 |
| TMEM263 | transmembrane protein 263 | 0.019102 |
| RHEB | Ras homolog enriched in brain | 0.0190587 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0190117 |
| YBX3 | Y box binding protein 3 | 0.0187077 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0186379 |
| EREG | epiregulin | 0.0184634 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0182453 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0180142 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0179282 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0178938 |
| PLAU | plasminogen activator, urokinase | 0.017707 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0175302 |
| SCEL | sciellin | 0.0175238 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0174822 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0173698 |
| SMYD3 | SET and MYND domain containing 3 | 0.0173377 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0172924 |
| SGMS2 | sphingomyelin synthase 2 | 0.0172228 |
| RPL34 | ribosomal protein L34 | 0.0171565 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0170447 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0167432 |
| EPCAM | epithelial cell adhesion molecule | 0.0167259 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0165979 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0165329 |
| CENPE | centromere protein E, 312kDa | 0.0165251 |
| RASAL2 | RAS protein activator like 2 | 0.0164989 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0164761 |
| SMAD3 | SMAD family member 3 | 0.0163189 |
| ARF1 | ADP-ribosylation factor 1 | 0.0161766 |
| IER3 | immediate early response 3 | 0.0161094 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.016103 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0160577 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0159532 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.015784 |
| TFRC | transferrin receptor | 0.0156448 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0156296 |
| CCDC47 | coiled-coil domain containing 47 | 0.0154379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.235633 |
| POTEF | POTE ankyrin domain family, member F | -0.222792 |
| NDRG1 | N-myc downstream regulated 1 | -0.221011 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.173626 |
| FTL | ferritin, light polypeptide | -0.159165 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.122084 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.120893 |
| TSC22D2 | TSC22 domain family, member 2 | -0.113423 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0879173 |
| HMGA1 | high mobility group AT-hook 1 | -0.0857902 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0804611 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.076713 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.069259 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0657543 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0645841 |
| LDHA | lactate dehydrogenase A | -0.063899 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0630726 |
| VEGFA | vascular endothelial growth factor A | -0.0625442 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0590911 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0585998 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0568699 |
| PCBP2 | poly(rC) binding protein 2 | -0.056193 |
| FAM13A | family with sequence similarity 13, member A | -0.0535872 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.053387 |
| UBC | ubiquitin C | -0.0533278 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0489761 |
| ACTG1 | actin gamma 1 | -0.046524 |
| MSN | moesin | -0.0458832 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0454042 |
| PKM | pyruvate kinase, muscle | -0.0445966 |
| FOSL1 | FOS-like antigen 1 | -0.0442135 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0441298 |
| RPS6 | ribosomal protein S6 | -0.0439655 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0405075 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0404232 |
| MXD1 | MAX dimerization protein 1 | -0.0401701 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0395288 |
| RPS23 | ribosomal protein S23 | -0.0393033 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.038234 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0371489 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0368558 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0366911 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0357879 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0357207 |
| HLA-A | major histocompatibility complex, class I, A | -0.0350421 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0347448 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0342345 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0340362 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0338965 |
| CLDN4 | claudin 4 | -0.0335367 |
| FN1 | fibronectin 1 | -0.0330248 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0313033 |
| FAM3C | family with sequence similarity 3, member C | -0.030897 |
| RNF145 | ring finger protein 145 | -0.0304167 |
| G0S2 | G0/G1 switch 2 | -0.0300989 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0300137 |
| YBX1 | Y box binding protein 1 | -0.0300113 |
| ENO1 | enolase 1, (alpha) | -0.0299985 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0299118 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.029664 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0296224 |
| DSTN | destrin (actin depolymerizing factor) | -0.0295607 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | -0.0293869 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0284594 |
| UPP1 | uridine phosphorylase 1 | -0.0283478 |
| WASF2 | WAS protein family, member 2 | -0.0279142 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0276824 |
| HLA-B | major histocompatibility complex, class I, B | -0.0276634 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0269464 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0268367 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0268015 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0265535 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0263108 |
| RPS19 | ribosomal protein S19 | -0.0258496 |
| ARRDC3 | arrestin domain containing 3 | -0.025397 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0252086 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0248954 |
| ADAR | adenosine deaminase, RNA-specific | -0.0248356 |
| TAPBP | TAP binding protein (tapasin) | -0.0243432 |
| RPLP2 | ribosomal protein, large, P2 | -0.0241705 |
| RIOK3 | RIO kinase 3 | -0.0238865 |
| CCNL1 | cyclin L1 | -0.0236128 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.023484 |
| RPS12 | ribosomal protein S12 | -0.0233156 |
| PFN1 | profilin 1 | -0.0232685 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0232512 |
| CDCP1 | CUB domain containing protein 1 | -0.023149 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0231183 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0229587 |
| S100A6 | S100 calcium binding protein A6 | -0.0228363 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0226324 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0224516 |
| CD109 | CD109 molecule | -0.0221228 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0221069 |
| RYBP | RING1 and YY1 binding protein | -0.0219066 |
| RHOA | ras homolog family member A | -0.0217377 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0213399 |
| RPL8 | ribosomal protein L8 | -0.0212286 |
| FAM162A | family with sequence similarity 162, member A | -0.0209782 |
| RPS13 | ribosomal protein S13 | -0.0205323 |
