| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.250646 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.230829 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.111243 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0882094 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0768935 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0705607 |
| CDH13 | cadherin 13 | 0.0704803 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0662975 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0631104 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0615178 |
| FMNL2 | formin-like 2 | 0.0597012 |
| PDE10A | phosphodiesterase 10A | 0.0578722 |
| SMAD2 | SMAD family member 2 | 0.0512152 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0510872 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0448831 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0439819 |
| DST | dystonin | 0.0436896 |
| VCL | vinculin | 0.041454 |
| INTS6 | integrator complex subunit 6 | 0.0407313 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0405753 |
| SQSTM1 | sequestosome 1 | 0.0398568 |
| CTBP2 | C-terminal binding protein 2 | 0.0398363 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0394477 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.039051 |
| AUTS2 | autism susceptibility candidate 2 | 0.0387319 |
| CUX1 | cut-like homeobox 1 | 0.0386594 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0369245 |
| DENND1A | DENN/MADD domain containing 1A | 0.0363518 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0361415 |
| HDAC4 | histone deacetylase 4 | 0.0359582 |
| PRELID2 | PRELI domain containing 2 | 0.0359304 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0358826 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0358749 |
| PCBP3 | poly(rC) binding protein 3 | 0.035719 |
| MAP7 | microtubule-associated protein 7 | 0.0340281 |
| CANX | calnexin | 0.0331191 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0323592 |
| XYLT1 | xylosyltransferase I | 0.032355 |
| DNER | delta/notch-like EGF repeat containing | 0.0309762 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0305564 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0300342 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0299211 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.02964 |
| FAM107B | family with sequence similarity 107, member B | 0.0296268 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0294645 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0293145 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0290417 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0280236 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0276969 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0276668 |
| GOLGA3 | golgin A3 | 0.0269091 |
| FNIP1 | folliculin interacting protein 1 | 0.026588 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0259372 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.025858 |
| RAB31 | RAB31, member RAS oncogene family | 0.025813 |
| AEBP2 | AE binding protein 2 | 0.0254383 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.025173 |
| LSAMP | limbic system-associated membrane protein | 0.0251565 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0250314 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0250017 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0247515 |
| SVIL | supervillin | 0.0245199 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0239839 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234935 |
| COPA | coatomer protein complex, subunit alpha | 0.0233745 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232651 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0231084 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0227105 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0225038 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.022392 |
| TENM2 | teneurin transmembrane protein 2 | 0.0223244 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0220466 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0219641 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0218553 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0216023 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0215583 |
| NTN4 | netrin 4 | 0.0214781 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0210241 |
| RAD51B | RAD51 paralog B | 0.0209437 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0209188 |
| FOXK1 | forkhead box K1 | 0.0206204 |
| SEPTIN9 | septin 9 | 0.0205824 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0203117 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0202998 |
| CALU | calumenin | 0.0202718 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0201872 |
| OXSR1 | oxidative stress responsive 1 | 0.0201597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0198462 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0197273 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0196093 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0196018 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0194418 |
| EPHA4 | EPH receptor A4 | 0.0193704 |
| ZNF644 | zinc finger protein 644 | 0.0189319 |
| EXOC4 | exocyst complex component 4 | 0.0187667 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0186854 |
| CADM2 | cell adhesion molecule 2 | 0.0185995 |
| PMM2 | phosphomannomutase 2 | 0.0185253 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0183291 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0183197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204611 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.184673 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.144971 |
| TXNRD1 | thioredoxin reductase 1 | -0.118797 |
| EFNA5 | ephrin-A5 | -0.116879 |
| ASPH | aspartate beta-hydroxylase | -0.116353 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.094004 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0816375 |
| NRCAM | neuronal cell adhesion molecule | -0.0759285 |
| NEK7 | NIMA-related kinase 7 | -0.0734467 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0696571 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0667951 |
| RTN4 | reticulon 4 | -0.0649923 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0624916 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0613462 |
| VIM | vimentin | -0.0613342 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0602617 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.055782 |
| CENPF | centromere protein F, 350/400kDa | -0.0513169 |
| FTL | ferritin, light polypeptide | -0.0502007 |
| TMSB10 | thymosin beta 10 | -0.0496023 |
| GDA | guanine deaminase | -0.0489265 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0485419 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0465058 |
| MFF | mitochondrial fission factor | -0.0464587 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0459901 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0449822 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0443522 |
| RPS6 | ribosomal protein S6 | -0.0421709 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0417658 |
| FN1 | fibronectin 1 | -0.0390651 |
| GRAMD1B | GRAM domain containing 1B | -0.0381749 |
| MKI67 | marker of proliferation Ki-67 | -0.0377028 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.036567 |
| PTGR1 | prostaglandin reductase 1 | -0.0362224 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0357294 |
| CTSC | cathepsin C | -0.0340778 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0340155 |
| ZNF292 | zinc finger protein 292 | -0.0335692 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0335114 |
| RPL23 | ribosomal protein L23 | -0.0332072 |
| LDHA | lactate dehydrogenase A | -0.0327754 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0319632 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0319138 |
| TNPO1 | transportin 1 | -0.0315498 |
| PGK1 | phosphoglycerate kinase 1 | -0.0315162 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0313047 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0312469 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0310485 |
| PCBP2 | poly(rC) binding protein 2 | -0.0305153 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0304046 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0294959 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0294298 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0293147 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0289663 |
| CARD16 | caspase recruitment domain family, member 16 | -0.028826 |
| POTEF | POTE ankyrin domain family, member F | -0.0287287 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.028581 |
| PYGL | phosphorylase, glycogen, liver | -0.0282889 |
| ENO1 | enolase 1, (alpha) | -0.0281725 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280712 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0277422 |
| SRGN | serglycin | -0.0276235 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274056 |
| PTMA | prothymosin, alpha | -0.0270885 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0270449 |
| RPL12 | ribosomal protein L12 | -0.0267857 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0267247 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0264632 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0261097 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0261024 |
| MATR3 | matrin 3 | -0.0258132 |
| YBX1 | Y box binding protein 1 | -0.0257719 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0254334 |
| RACK1 | receptor for activated C kinase 1 | -0.0249977 |
| ENAH | enabled homolog (Drosophila) | -0.0246556 |
| DIAPH3 | diaphanous-related formin 3 | -0.0245297 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0244939 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0242797 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0239067 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0236731 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236555 |
| PFN1 | profilin 1 | -0.0236243 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0235029 |
| FAM13A | family with sequence similarity 13, member A | -0.0234905 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0234594 |
| ATP13A3 | ATPase type 13A3 | -0.0234207 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0233072 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0231992 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0231685 |
| PKM | pyruvate kinase, muscle | -0.0231299 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0230551 |
| LDHB | lactate dehydrogenase B | -0.0230116 |
| MAP1B | microtubule-associated protein 1B | -0.0230025 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.022842 |
| USP3 | ubiquitin specific peptidase 3 | -0.0228273 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0224036 |
| OSMR | oncostatin M receptor | -0.0223767 |
| CDK6 | cyclin-dependent kinase 6 | -0.0223333 |
| RPS19 | ribosomal protein S19 | -0.0221445 |
