| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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132 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.373304 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.14667 |
| NAV2 | neuron navigator 2 | 0.125154 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.10682 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0976224 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0975589 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0975493 |
| CDH13 | cadherin 13 | 0.0974565 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.093672 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0874142 |
| WASF2 | WAS protein family, member 2 | 0.0873586 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0853222 |
| EZR | ezrin | 0.0831965 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0796198 |
| PRKCA | protein kinase C, alpha | 0.0764584 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0726921 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.071436 |
| STC1 | stanniocalcin 1 | 0.0705987 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0705847 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0693331 |
| PDE10A | phosphodiesterase 10A | 0.0678684 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0574861 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0573714 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0557833 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0548375 |
| ITGA6 | integrin, alpha 6 | 0.0546847 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0520648 |
| MYOF | myoferlin | 0.0519302 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0502386 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.047094 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0457561 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0453174 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0446732 |
| INHBA | inhibin, beta A | 0.0437756 |
| RBM25 | RNA binding motif protein 25 | 0.043597 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0413615 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0407701 |
| MYO5B | myosin VB | 0.0368307 |
| MED13L | mediator complex subunit 13-like | 0.0358349 |
| KIF5B | kinesin family member 5B | 0.0330203 |
| STAG2 | stromal antigen 2 | 0.0311559 |
| AHNAK | AHNAK nucleoprotein | 0.0281557 |
| FLNB | filamin B, beta | 0.0278184 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0273983 |
| RPS16 | ribosomal protein S16 | 0.027325 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0268794 |
| RPLP1 | ribosomal protein, large, P1 | 0.0261783 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0247103 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0242537 |
| LMO7 | LIM domain 7 | 0.0238038 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0235103 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0192372 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0187086 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0182459 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0179003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0166975 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0162249 |
| SNX9 | sorting nexin 9 | 0.0160569 |
| POTEF | POTE ankyrin domain family, member F | 0.0145141 |
| JMJD1C | jumonji domain containing 1C | 0.0139404 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.012744 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0107713 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0103968 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0089809 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.00870751 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00702246 |
| RPLP2 | ribosomal protein, large, P2 | 0.00536704 |
| ASPH | aspartate beta-hydroxylase | 0.00312365 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.00301135 |
| OGA | O-GlcNAcase | 0.00182851 |
| DST | dystonin | 0.00182368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.262007 |
| FN1 | fibronectin 1 | -0.197488 |
| NDRG1 | N-myc downstream regulated 1 | -0.143869 |
| VIM | vimentin | -0.137172 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.125524 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.121347 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.118804 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.117091 |
| RPS6 | ribosomal protein S6 | -0.116691 |
| GPC6 | glypican 6 | -0.115433 |
| LDHA | lactate dehydrogenase A | -0.111312 |
| TMSB10 | thymosin beta 10 | -0.101487 |
| EFNA5 | ephrin-A5 | -0.0973318 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0969577 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0951113 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0854267 |
| PTMA | prothymosin, alpha | -0.0818536 |
| CANX | calnexin | -0.0778074 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0767916 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0740685 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0728535 |
| PKM | pyruvate kinase, muscle | -0.0665883 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0631684 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0600527 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.059486 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0565819 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0542055 |
| SBF2 | SET binding factor 2 | -0.0526336 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0513907 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.049199 |
| MT2A | metallothionein 2A | -0.0421561 |
| ANXA2 | annexin A2 | -0.0417973 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388301 |
| SPAG9 | sperm associated antigen 9 | -0.0377392 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0357961 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0336414 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0336094 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.032456 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0301273 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.029908 |
| CD44 | CD44 molecule (Indian blood group) | -0.0291542 |
| RPL23 | ribosomal protein L23 | -0.0255122 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0236686 |
| PGK1 | phosphoglycerate kinase 1 | -0.0224647 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0217825 |
| PARD3 | par-3 family cell polarity regulator | -0.0179215 |
| LAMB3 | laminin, beta 3 | -0.0165471 |
| RPL26 | ribosomal protein L26 | -0.0163662 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0153743 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0148382 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0138411 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0137492 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0133715 |
| GOLGB1 | golgin B1 | -0.0128083 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.00914708 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.00801804 |
| RPS8 | ribosomal protein S8 | -0.0073539 |
| MYO1E | myosin IE | -0.00719262 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00682211 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00658669 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00603056 |
