| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0754976 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0467869 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0427297 |
| TEX11 | testis expressed 11 | 0.0396038 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0382709 |
| CKAP5 | cytoskeleton associated protein 5 | 0.037362 |
| CENPF | centromere protein F, 350/400kDa | 0.034738 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0338536 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0312198 |
| R3HDM1 | R3H domain containing 1 | 0.0310117 |
| CFL2 | cofilin 2 (muscle) | 0.030344 |
| ECT2 | epithelial cell transforming 2 | 0.0302741 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0300412 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0291567 |
| PCDH7 | protocadherin 7 | 0.0287103 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0282507 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0272081 |
| KIF4A | kinesin family member 4A | 0.0269279 |
| TXNRD1 | thioredoxin reductase 1 | 0.0265544 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0259837 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0257785 |
| CEP192 | centrosomal protein 192kDa | 0.0255607 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0254591 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0249088 |
| TPX2 | TPX2, microtubule-associated | 0.0248148 |
| CENPE | centromere protein E, 312kDa | 0.0245606 |
| ENAH | enabled homolog (Drosophila) | 0.0244178 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0244021 |
| USP34 | ubiquitin specific peptidase 34 | 0.0241325 |
| KIF23 | kinesin family member 23 | 0.0241189 |
| FER | fer (fps/fes related) tyrosine kinase | 0.023914 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0237252 |
| FN1 | fibronectin 1 | 0.0236225 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0235404 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0235286 |
| CORO1C | coronin, actin binding protein, 1C | 0.0233123 |
| BBX | bobby sox homolog (Drosophila) | 0.0232572 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0232555 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0232392 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.022905 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0228135 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0217575 |
| UTRN | utrophin | 0.0217294 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0213529 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0213511 |
| NCKAP1 | NCK-associated protein 1 | 0.0209804 |
| EPHA3 | EPH receptor A3 | 0.0205721 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0205551 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0205503 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0203983 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0203816 |
| ABI2 | abl-interactor 2 | 0.020224 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0201722 |
| TMPO | thymopoietin | 0.0200687 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0200582 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0200148 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0200007 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0198856 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0198513 |
| SGO2 | shugoshin 2 | 0.0198483 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0197455 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0196694 |
| TGFB2 | transforming growth factor, beta 2 | 0.0194734 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0194725 |
| AK1 | adenylate kinase 1 | 0.0194391 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0194234 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0193902 |
| FAT1 | FAT atypical cadherin 1 | 0.0193677 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0193616 |
| PARD3 | par-3 family cell polarity regulator | 0.0192675 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0191091 |
| RAB30 | RAB30, member RAS oncogene family | 0.0189558 |
| DIAPH3 | diaphanous-related formin 3 | 0.0188378 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187185 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0186638 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0185479 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0183894 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0182516 |
| CCNL1 | cyclin L1 | 0.0181217 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0180937 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0180486 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0178958 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.017565 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0175626 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0172733 |
| MELK | maternal embryonic leucine zipper kinase | 0.0172192 |
| TMSB4X | thymosin beta 4, X-linked | 0.0171733 |
| RNF13 | ring finger protein 13 | 0.0171717 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.0170988 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0169818 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0168664 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0168295 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0168105 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0167657 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.016761 |
| EXOC4 | exocyst complex component 4 | 0.0166824 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.016599 |
| ANXA5 | annexin A5 | 0.0165845 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0165635 |
| CAPN7 | calpain 7 | 0.0165006 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.12256 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118598 |
| PTMA | prothymosin, alpha | -0.102073 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0950527 |
| TMSB10 | thymosin beta 10 | -0.0918739 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0732255 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0724021 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0640584 |
| RPS16 | ribosomal protein S16 | -0.0634417 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0611529 |
| PLPP1 | phospholipid phosphatase 1 | -0.05891 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0574071 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0571588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0536087 |
| RPS8 | ribosomal protein S8 | -0.0522695 |
| SPAG9 | sperm associated antigen 9 | -0.0507757 |
| RPL11 | ribosomal protein L11 | -0.050309 |
| RPLP1 | ribosomal protein, large, P1 | -0.0474858 |
| RPL19 | ribosomal protein L19 | -0.0471823 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0447501 |
| RPS12 | ribosomal protein S12 | -0.0445134 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0445045 |
| RPS6 | ribosomal protein S6 | -0.0440804 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0435987 |
| GNAS | GNAS complex locus | -0.0434831 |
| SRP72 | signal recognition particle 72kDa | -0.0430983 |
| RPL37A | ribosomal protein L37a | -0.0429988 |
| NOP58 | NOP58 ribonucleoprotein | -0.0423954 |
| RPS3 | ribosomal protein S3 | -0.0417584 |
| PHIP | pleckstrin homology domain interacting protein | -0.0416797 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0416671 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0406183 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0401374 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398955 |
| RPL37 | ribosomal protein L37 | -0.039799 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0397742 |
| COL1A2 | collagen, type I, alpha 2 | -0.0385289 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0382048 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.037919 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0377619 |
| ACTG1 | actin gamma 1 | -0.0370396 |
| RPLP2 | ribosomal protein, large, P2 | -0.0366692 |
| RPS21 | ribosomal protein S21 | -0.0356839 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0355462 |
| RPS23 | ribosomal protein S23 | -0.0354798 |
| RPS19 | ribosomal protein S19 | -0.034913 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0348998 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0347945 |
| RPL26 | ribosomal protein L26 | -0.0340128 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.033806 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0332884 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0332772 |
| CADM2 | cell adhesion molecule 2 | -0.0331581 |
| RPL30 | ribosomal protein L30 | -0.0331226 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0329934 |
| RPL12 | ribosomal protein L12 | -0.0329521 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0328179 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0322325 |
| RPL13A | ribosomal protein L13a | -0.032074 |
| PCDH9 | protocadherin 9 | -0.0317976 |
| HDAC9 | histone deacetylase 9 | -0.0311907 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0307046 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0300576 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0300065 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.029527 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0288091 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0287135 |
| RPS4X | ribosomal protein S4, X-linked | -0.0286565 |
| RPL35A | ribosomal protein L35a | -0.0285299 |
| WDR43 | WD repeat domain 43 | -0.0283391 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0281204 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.027848 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0277425 |
| ZNF292 | zinc finger protein 292 | -0.0274916 |
| RPS24 | ribosomal protein S24 | -0.027384 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0271887 |
| USP53 | ubiquitin specific peptidase 53 | -0.0271129 |
| MYO10 | myosin X | -0.0268859 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0267122 |
| QKI | QKI, KH domain containing, RNA binding | -0.0266469 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0266205 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0265621 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0264456 |
| RAB1A | RAB1A, member RAS oncogene family | -0.026409 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.026406 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0263114 |
| MTREX | Mtr4 exosome RNA helicase | -0.0260967 |
| CCN2 | cellular communication network factor 2 | -0.026094 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0260835 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0259558 |
| RPL32 | ribosomal protein L32 | -0.0257757 |
| NFIA | nuclear factor I/A | -0.0256761 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0253978 |
| PHF21A | PHD finger protein 21A | -0.0253658 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252605 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0252596 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0251469 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0250213 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0246819 |
| EVI5 | ecotropic viral integration site 5 | -0.0245575 |
