| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.180722 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.11231 |
| RPS16 | ribosomal protein S16 | 0.0530256 |
| CANX | calnexin | 0.051461 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0506922 |
| FBL | fibrillarin | 0.0383769 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0369839 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0357176 |
| GOLGA4 | golgin A4 | 0.0299543 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0294298 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0285373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0268579 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0255054 |
| SQSTM1 | sequestosome 1 | 0.0254462 |
| BRD2 | bromodomain containing 2 | 0.0242538 |
| HM13 | histocompatibility (minor) 13 | 0.0233686 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0229237 |
| UPP1 | uridine phosphorylase 1 | 0.0229232 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0223824 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0220719 |
| HYOU1 | hypoxia up-regulated 1 | 0.0208975 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0206048 |
| WDR45B | WD repeat domain 45B | 0.0204943 |
| SUCO | SUN domain containing ossification factor | 0.0204432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0200621 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0198045 |
| HDLBP | high density lipoprotein binding protein | 0.0197515 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0193576 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0193494 |
| SRP54 | signal recognition particle 54kDa | 0.0182863 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0180328 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0179861 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0179745 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0179291 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0177505 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0177308 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0174829 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0174223 |
| GOLGA3 | golgin A3 | 0.0170317 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0169812 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0166088 |
| INTS6 | integrator complex subunit 6 | 0.0164584 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0160996 |
| MED29 | mediator complex subunit 29 | 0.015864 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.015792 |
| VEGFA | vascular endothelial growth factor A | 0.0157729 |
| RPS25 | ribosomal protein S25 | 0.0155695 |
| GOLGB1 | golgin B1 | 0.0152998 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0152874 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.015242 |
| MORF4L2 | mortality factor 4 like 2 | 0.0152057 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0151097 |
| USP36 | ubiquitin specific peptidase 36 | 0.0146302 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0144669 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0140133 |
| SFTPA2 | surfactant protein A2 | 0.013544 |
| PGM3 | phosphoglucomutase 3 | 0.0135131 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0132367 |
| ARF4 | ADP-ribosylation factor 4 | 0.013218 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0131817 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0130586 |
| OGA | O-GlcNAcase | 0.0129928 |
| ATF6 | activating transcription factor 6 | 0.0129722 |
| ATF3 | activating transcription factor 3 | 0.0128352 |
| NUP58 | nucleoporin 58 | 0.0127567 |
| TMEM123 | transmembrane protein 123 | 0.0126438 |
| RIOK3 | RIO kinase 3 | 0.0125402 |
| NDRG1 | N-myc downstream regulated 1 | 0.0122523 |
| CALR | calreticulin | 0.0121537 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0119891 |
| ZNF146 | zinc finger protein 146 | 0.0119793 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0116902 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0115895 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0115383 |
| STX5 | syntaxin 5 | 0.0114816 |
| RBM39 | RNA binding motif protein 39 | 0.0114282 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0113733 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0112813 |
| ADM | adrenomedullin | 0.011127 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0110603 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0110128 |
| SEC24A | SEC24 family member A | 0.010896 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0108889 |
| CALU | calumenin | 0.0107593 |
| TMEM39A | transmembrane protein 39A | 0.0106527 |
| USP37 | ubiquitin specific peptidase 37 | 0.0106312 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0105996 |
| TMEM165 | transmembrane protein 165 | 0.0104289 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0103298 |
| SEC24D | SEC24 family member D | 0.0102818 |
| SAFB2 | scaffold attachment factor B2 | 0.0102514 |
| TMEM263 | transmembrane protein 263 | 0.0102147 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0101745 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0101072 |
| COPA | coatomer protein complex, subunit alpha | 0.0100636 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0100294 |
| TRAM1 | translocation associated membrane protein 1 | 0.00996168 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | 0.00993283 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00990101 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00987019 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.154854 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.11781 |
| MT2A | metallothionein 2A | -0.116704 |
| CD44 | CD44 molecule (Indian blood group) | -0.113092 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.106572 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.106308 |
| DST | dystonin | -0.0978016 |
| VCL | vinculin | -0.0976918 |
| VIM | vimentin | -0.0945346 |
| ACTN4 | actinin, alpha 4 | -0.091913 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0761251 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0753898 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0738817 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0667391 |
| SMAD3 | SMAD family member 3 | -0.0665562 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.066087 |
| RPS3 | ribosomal protein S3 | -0.0643061 |
| AHNAK | AHNAK nucleoprotein | -0.0637531 |
| RPS12 | ribosomal protein S12 | -0.0635852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0625081 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0620826 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0617727 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0613012 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0612356 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0596974 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0569479 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0567294 |
| ASPH | aspartate beta-hydroxylase | -0.0561054 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0552828 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0552653 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0542679 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0540834 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.05371 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0516677 |
| PTK2 | protein tyrosine kinase 2 | -0.0513136 |
| PTMA | prothymosin, alpha | -0.0482765 |
| MYOF | myoferlin | -0.0462785 |
| RTN4 | reticulon 4 | -0.0454935 |
| RPLP2 | ribosomal protein, large, P2 | -0.0452426 |
| PDE10A | phosphodiesterase 10A | -0.0450051 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.042314 |
| ZNF780B | zinc finger protein 780B | -0.0422494 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0408675 |
| RPL11 | ribosomal protein L11 | -0.0407932 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0405845 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0405308 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0399899 |
| RPL23 | ribosomal protein L23 | -0.0399841 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.039358 |
| SMYD3 | SET and MYND domain containing 3 | -0.0392803 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0383965 |
| SBF2 | SET binding factor 2 | -0.037891 |
| HMGA2 | high mobility group AT-hook 2 | -0.0376587 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.037073 |
| EGFR | epidermal growth factor receptor | -0.0369691 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0364937 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0364776 |
| AFAP1 | actin filament associated protein 1 | -0.036414 |
| MYO10 | myosin X | -0.0361222 |
| EFNA5 | ephrin-A5 | -0.0357292 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.035543 |
| DIAPH2 | diaphanous-related formin 2 | -0.035303 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0352484 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0349474 |
| RPLP1 | ribosomal protein, large, P1 | -0.0346607 |
| PHF14 | PHD finger protein 14 | -0.0345669 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.03451 |
| ATG7 | autophagy related 7 | -0.0339974 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0338452 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.03381 |
| THOC2 | THO complex 2 | -0.0337811 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0335252 |
| NF1 | neurofibromin 1 | -0.0334505 |
| MED13L | mediator complex subunit 13-like | -0.0332832 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0332322 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0331528 |
| CENPF | centromere protein F, 350/400kDa | -0.033145 |
| JMJD1C | jumonji domain containing 1C | -0.0327618 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.032484 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0324446 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0323027 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0322925 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0322896 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0319041 |
| RPS17 | ribosomal protein S17 | -0.0317203 |
| CDK6 | cyclin-dependent kinase 6 | -0.0315897 |
| RASAL2 | RAS protein activator like 2 | -0.0312283 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0311174 |
| RPLP0 | ribosomal protein, large, P0 | -0.0310361 |
| ACTG1 | actin gamma 1 | -0.0309155 |
| LDHA | lactate dehydrogenase A | -0.0307473 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0305891 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0305433 |
| RNF220 | ring finger protein 220 | -0.0302622 |
| PRSS23 | protease, serine, 23 | -0.0298849 |
| EXOC4 | exocyst complex component 4 | -0.0298235 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295612 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0290194 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0287783 |
| B2M | beta-2-microglobulin | -0.028708 |
