| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.224785 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.134321 |
| CANX | calnexin | 0.0807706 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0767798 |
| AHNAK | AHNAK nucleoprotein | 0.0744466 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0718278 |
| OGA | O-GlcNAcase | 0.0676236 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0669932 |
| RUNX1 | runt-related transcription factor 1 | 0.0592827 |
| ACTG1 | actin gamma 1 | 0.0590487 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0568492 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0547365 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0546531 |
| SMAD3 | SMAD family member 3 | 0.0523646 |
| TMSB4X | thymosin beta 4, X-linked | 0.0505482 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0492379 |
| RBM39 | RNA binding motif protein 39 | 0.0489428 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0467085 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0425082 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0422179 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0405349 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0398338 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0395515 |
| SQSTM1 | sequestosome 1 | 0.0390612 |
| NAV2 | neuron navigator 2 | 0.0382192 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0378538 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0371078 |
| DSCAM | Down syndrome cell adhesion molecule | 0.036737 |
| AFDN | afadin, adherens junction formation factor | 0.0366275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0359731 |
| LAMC2 | laminin, gamma 2 | 0.0359353 |
| FUS | FUS RNA binding protein | 0.0351592 |
| H1-0 | H1.0 linker histone | 0.0347196 |
| CD2AP | CD2-associated protein | 0.0347096 |
| RPS21 | ribosomal protein S21 | 0.0344052 |
| FRMD5 | FERM domain containing 5 | 0.034275 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0342678 |
| RAD21 | RAD21 homolog (S. pombe) | 0.033198 |
| RRBP1 | ribosome binding protein 1 | 0.0330578 |
| FLNA | filamin A, alpha | 0.0325069 |
| XPO1 | exportin 1 | 0.0320127 |
| CALU | calumenin | 0.0314646 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0312566 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0307074 |
| TJP1 | tight junction protein 1 | 0.0304944 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0298865 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0294113 |
| FMNL2 | formin-like 2 | 0.02855 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0284562 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.028151 |
| KLF6 | Kruppel-like factor 6 | 0.0280366 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0279078 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0278921 |
| DSG2 | desmoglein 2 | 0.0276737 |
| CLTC | clathrin, heavy chain (Hc) | 0.0272431 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0270929 |
| EZR | ezrin | 0.0270388 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0267737 |
| CALR | calreticulin | 0.0265775 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0264729 |
| MYO5B | myosin VB | 0.026019 |
| SDC4 | syndecan 4 | 0.0259526 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.025892 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0258698 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0258102 |
| EMP1 | epithelial membrane protein 1 | 0.0256761 |
| CEP95 | centrosomal protein 95kDa | 0.0255066 |
| RBM25 | RNA binding motif protein 25 | 0.0253368 |
| ACTN4 | actinin, alpha 4 | 0.0253111 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0252616 |
| MYO6 | myosin VI | 0.0252295 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0250579 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.025022 |
| AFF4 | AF4/FMR2 family, member 4 | 0.024863 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0248444 |
| RPS24 | ribosomal protein S24 | 0.0248327 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0248289 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0247539 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0247012 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0246963 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.024548 |
| COPA | coatomer protein complex, subunit alpha | 0.0245121 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245008 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0243772 |
| MED13 | mediator complex subunit 13 | 0.0240881 |
| HDLBP | high density lipoprotein binding protein | 0.0240719 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0237862 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0237509 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0236669 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.023508 |
| SPAG9 | sperm associated antigen 9 | 0.0234274 |
| GRAMD2B | GRAM domain containing 2B | 0.0234209 |
| HELZ | helicase with zinc finger | 0.0234085 |
| CLINT1 | clathrin interactor 1 | 0.0233163 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0233148 |
| YBX3 | Y box binding protein 3 | 0.0232715 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0232661 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0231896 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0230628 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0228127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC16 | mucin 16, cell surface associated | -0.140807 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.12182 |
| RPS3 | ribosomal protein S3 | -0.0815837 |
| INTS6 | integrator complex subunit 6 | -0.0787713 |
| MUC4 | mucin 4, cell surface associated | -0.0777753 |
| POTEF | POTE ankyrin domain family, member F | -0.0756132 |
| RACK1 | receptor for activated C kinase 1 | -0.0740694 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0726136 |
| HMGA1 | high mobility group AT-hook 1 | -0.0700664 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0696897 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0691166 |
| B2M | beta-2-microglobulin | -0.0645924 |
| PLSCR1 | phospholipid scramblase 1 | -0.0617575 |
| C3 | complement component 3 | -0.0600683 |
| TAPBP | TAP binding protein (tapasin) | -0.0582601 |
| RPS12 | ribosomal protein S12 | -0.0581984 |
| EGFR | epidermal growth factor receptor | -0.0538447 |
| RPL23 | ribosomal protein L23 | -0.053783 |
| TGM2 | transglutaminase 2 | -0.053224 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.051994 |
| LDHA | lactate dehydrogenase A | -0.0506689 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0490377 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0485568 |
| RPL31 | ribosomal protein L31 | -0.0478566 |
| SYT14 | synaptotagmin XIV | -0.0472182 |
| RAD51B | RAD51 paralog B | -0.0470911 |
| RPS6 | ribosomal protein S6 | -0.0469852 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0461359 |
| VEGFA | vascular endothelial growth factor A | -0.0451687 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0451184 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0451092 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0447644 |
| RPS17 | ribosomal protein S17 | -0.0443428 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0440246 |
| HLA-A | major histocompatibility complex, class I, A | -0.0427531 |
| IFI44 | interferon-induced protein 44 | -0.0423433 |
| PKM | pyruvate kinase, muscle | -0.041439 |
| IFI44L | interferon-induced protein 44-like | -0.0413587 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0413243 |
| RPS27 | ribosomal protein S27 | -0.0405444 |
| FTL | ferritin, light polypeptide | -0.0392285 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0389111 |
| MX1 | MX dynamin-like GTPase 1 | -0.0384581 |
| DAPK1 | death-associated protein kinase 1 | -0.037381 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0373194 |
| RPL37A | ribosomal protein L37a | -0.0370367 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.03683 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0366787 |
| RPS19 | ribosomal protein S19 | -0.0355179 |
| FHIT | fragile histidine triad | -0.0348019 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0346256 |
| GOLGB1 | golgin B1 | -0.0342005 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.034154 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0340232 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0339055 |
| CLDN4 | claudin 4 | -0.032804 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0323442 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.032128 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0320069 |
| OSMR | oncostatin M receptor | -0.0319408 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0316782 |
| RPL28 | ribosomal protein L28 | -0.0314698 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0309839 |
| HDAC9 | histone deacetylase 9 | -0.0308435 |
| ANXA2 | annexin A2 | -0.0304566 |
| ITGB6 | integrin, beta 6 | -0.0304158 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0303686 |
| TPI1 | triosephosphate isomerase 1 | -0.0302054 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0301403 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0297517 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0296605 |
| RPL37 | ribosomal protein L37 | -0.029635 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0294694 |
| DPYD | dihydropyrimidine dehydrogenase | -0.029463 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0293419 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0292666 |
| EFNA5 | ephrin-A5 | -0.0290957 |
| RPL36 | ribosomal protein L36 | -0.0287806 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0287239 |
| VMP1 | vacuole membrane protein 1 | -0.0284554 |
| RPL10A | ribosomal protein L10a | -0.0282665 |
| JUP | junction plakoglobin | -0.0280707 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.027933 |
| MYO1E | myosin IE | -0.0278664 |
| RPL30 | ribosomal protein L30 | -0.0272985 |
| TMSB10 | thymosin beta 10 | -0.02726 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0271853 |
| RPL18 | ribosomal protein L18 | -0.0270203 |
| EXOC4 | exocyst complex component 4 | -0.0267995 |
| PCDH1 | protocadherin 1 | -0.0262078 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0259085 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0257275 |
| HLA-B | major histocompatibility complex, class I, B | -0.0256181 |
| SULF2 | sulfatase 2 | -0.0255788 |
| HDGF | hepatoma-derived growth factor | -0.0250181 |
| RCOR1 | REST corepressor 1 | -0.0247602 |
| MEF2A | myocyte enhancer factor 2A | -0.0246003 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.02451 |
| LMO7 | LIM domain 7 | -0.0243466 |
| KYNU | kynureninase | -0.0241506 |
