| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD6 | FERM domain containing 6 | 0.133556 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.100196 |
| ZNF438 | zinc finger protein 438 | 0.0963281 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0933505 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0817583 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0753745 |
| NABP1 | nucleic acid binding protein 1 | 0.0649398 |
| HMGA2 | high mobility group AT-hook 2 | 0.0618913 |
| NAV2 | neuron navigator 2 | 0.059352 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0567835 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0513222 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0447639 |
| MCL1 | myeloid cell leukemia 1 | 0.042171 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0415013 |
| INTS6 | integrator complex subunit 6 | 0.0411904 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0406011 |
| SGMS2 | sphingomyelin synthase 2 | 0.0401601 |
| RAD51B | RAD51 paralog B | 0.0400414 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0399342 |
| FHIT | fragile histidine triad | 0.0397232 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0380979 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.035065 |
| DGKI | diacylglycerol kinase, iota | 0.0332842 |
| ASPH | aspartate beta-hydroxylase | 0.0322346 |
| SP100 | SP100 nuclear antigen | 0.0320466 |
| EXOC4 | exocyst complex component 4 | 0.0312636 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0301183 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282036 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0280501 |
| MSH4 | mutS homolog 4 | 0.0271808 |
| MTAP | methylthioadenosine phosphorylase | 0.0260747 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0256965 |
| MYRFL | myelin regulatory factor-like | 0.0255669 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0253546 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0253399 |
| AEBP2 | AE binding protein 2 | 0.0246857 |
| RCOR1 | REST corepressor 1 | 0.0246175 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0244746 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0242345 |
| ANK2 | ankyrin 2, neuronal | 0.02406 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0237875 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0235471 |
| BNC2 | basonuclin 2 | 0.0234057 |
| NAV3 | neuron navigator 3 | 0.0224326 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0223991 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.022255 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0220593 |
| SFPQ | splicing factor proline/glutamine-rich | 0.021563 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0198564 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0193479 |
| SMYD3 | SET and MYND domain containing 3 | 0.0192131 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0191311 |
| AHNAK | AHNAK nucleoprotein | 0.0188865 |
| EFNB2 | ephrin-B2 | 0.018817 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0186397 |
| CAST | calpastatin | 0.0181301 |
| HDAC4 | histone deacetylase 4 | 0.0180658 |
| SKI | SKI proto-oncogene | 0.0180582 |
| FRMD4A | FERM domain containing 4A | 0.0179068 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0177018 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0176305 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0175246 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0175229 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0174537 |
| TRIM44 | tripartite motif containing 44 | 0.0173664 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0173215 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0171931 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0169163 |
| RIGI | RNA sensor RIG-I | 0.0167018 |
| FLNB | filamin B, beta | 0.01629 |
| PUM3 | pumilio RNA binding family member 3 | 0.0162391 |
| WWOX | WW domain containing oxidoreductase | 0.0161431 |
| GPATCH2L | G patch domain containing 2-like | 0.0161298 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0159657 |
| RASAL2 | RAS protein activator like 2 | 0.0158934 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0157429 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0156391 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0155228 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | 0.0155057 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.015373 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0152636 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0151351 |
| NEK10 | NIMA-related kinase 10 | 0.015069 |
| PHF14 | PHD finger protein 14 | 0.0144675 |
| DENND1A | DENN/MADD domain containing 1A | 0.0144314 |
| NLK | nemo-like kinase | 0.0144294 |
| CCDC91 | coiled-coil domain containing 91 | 0.0143906 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 | 0.0143811 |
| PRELID2 | PRELI domain containing 2 | 0.0142739 |
| FLNA | filamin A, alpha | 0.0142456 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0142387 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0142203 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0142152 |
| WDR27 | WD repeat domain 27 | 0.014111 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0140712 |
| CAPRIN2 | caprin family member 2 | 0.0138508 |
| PRKCE | protein kinase C, epsilon | 0.0137518 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0137157 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0136287 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.013426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.195599 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14455 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.120945 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118474 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.115589 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0877815 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0864223 |
| MTDH | metadherin | -0.0752832 |
| RPS6 | ribosomal protein S6 | -0.0747993 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.074116 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0727261 |
| LAMB3 | laminin, beta 3 | -0.071603 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0711936 |
| ACTG1 | actin gamma 1 | -0.0700541 |
| GOLGA4 | golgin A4 | -0.067877 |
| RPL8 | ribosomal protein L8 | -0.066081 |
| TPM4 | tropomyosin 4 | -0.0647415 |
| MT2A | metallothionein 2A | -0.059978 |
| STC1 | stanniocalcin 1 | -0.0599193 |
| NUP58 | nucleoporin 58 | -0.0584588 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0581426 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0541226 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0533057 |
| TXNRD1 | thioredoxin reductase 1 | -0.051695 |
| CANX | calnexin | -0.0514546 |
| RPL7A | ribosomal protein L7a | -0.0495798 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0493277 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0489772 |
| USP3 | ubiquitin specific peptidase 3 | -0.0489427 |
| TPD52 | tumor protein D52 | -0.0475322 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0468473 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0468315 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0467874 |
| NF1 | neurofibromin 1 | -0.0462972 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0461807 |
| RLF | rearranged L-myc fusion | -0.0458119 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0454981 |
| FTL | ferritin, light polypeptide | -0.0449526 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0447768 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.044644 |
| RPL35A | ribosomal protein L35a | -0.0446018 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0439241 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0436351 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.043205 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0426345 |
| ZNF292 | zinc finger protein 292 | -0.0426015 |
| CALD1 | caldesmon 1 | -0.0420492 |
| PTK2 | protein tyrosine kinase 2 | -0.0417453 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0410597 |
| PGK1 | phosphoglycerate kinase 1 | -0.0403728 |
| RPLP1 | ribosomal protein, large, P1 | -0.0401199 |
| PTMA | prothymosin, alpha | -0.0401169 |
| TTR | transthyretin | -0.0400544 |
| JMJD1C | jumonji domain containing 1C | -0.0393415 |
| RTN4 | reticulon 4 | -0.039302 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0392703 |
| HMGA1 | high mobility group AT-hook 1 | -0.0391207 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0390579 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0390426 |
| RPL12 | ribosomal protein L12 | -0.0385762 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0384476 |
| CALR | calreticulin | -0.0381491 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0371338 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0368836 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0367334 |
| ENO1 | enolase 1, (alpha) | -0.0364647 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0359651 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0356914 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0352258 |
| RPS8 | ribosomal protein S8 | -0.0349737 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0348203 |
| KIF5B | kinesin family member 5B | -0.0346798 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0345596 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0342041 |
| RPL19 | ribosomal protein L19 | -0.0340026 |
| CALU | calumenin | -0.0339205 |
| SETD5 | SET domain containing 5 | -0.0334418 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0328496 |
| PHIP | pleckstrin homology domain interacting protein | -0.0328364 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0328181 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0323796 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0323311 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0322165 |
| ARFGEF3 | ARFGEF family member 3 | -0.0321423 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0319212 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0316119 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0315814 |
| SBF2 | SET binding factor 2 | -0.0314912 |
| MATR3 | matrin 3 | -0.0314514 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0312201 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.031058 |
| GNAS | GNAS complex locus | -0.0310493 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0310409 |
| RPL7 | ribosomal protein L7 | -0.030984 |
| LDHA | lactate dehydrogenase A | -0.0309559 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.030866 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0307282 |
| SRPK2 | SRSF protein kinase 2 | -0.0305561 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0301343 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0299132 |
