| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | 0.181547 |
| FN1 | fibronectin 1 | 0.127683 |
| HLA-B | major histocompatibility complex, class I, B | 0.104063 |
| COL1A2 | collagen, type I, alpha 2 | 0.102196 |
| AHNAK | AHNAK nucleoprotein | 0.0805099 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0759057 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0719537 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0703826 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0696407 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0661166 |
| NAV1 | neuron navigator 1 | 0.0571625 |
| RRBP1 | ribosome binding protein 1 | 0.0556863 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0502999 |
| COL5A3 | collagen, type V, alpha 3 | 0.0487026 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0484045 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0479827 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0461907 |
| SMAD3 | SMAD family member 3 | 0.0448611 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0400206 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0390958 |
| COL4A2 | collagen, type IV, alpha 2 | 0.039093 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0387818 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0381489 |
| SP100 | SP100 nuclear antigen | 0.0379271 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0378706 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0378379 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0378046 |
| TPM4 | tropomyosin 4 | 0.0377509 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0376274 |
| SQSTM1 | sequestosome 1 | 0.0371085 |
| LYST | lysosomal trafficking regulator | 0.0369111 |
| FAT1 | FAT atypical cadherin 1 | 0.0362771 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0357005 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0350957 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0349658 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0342746 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0339922 |
| FRMD4A | FERM domain containing 4A | 0.0336429 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0335042 |
| CALU | calumenin | 0.0330407 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0327846 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0318658 |
| SMYD3 | SET and MYND domain containing 3 | 0.0314448 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0311975 |
| MLPH | melanophilin | 0.0310352 |
| HDLBP | high density lipoprotein binding protein | 0.0306028 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0304346 |
| TGFB1 | transforming growth factor, beta 1 | 0.0303566 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0301078 |
| ACTG1 | actin gamma 1 | 0.0297586 |
| INHBA | inhibin, beta A | 0.0297571 |
| RIGI | RNA sensor RIG-I | 0.0294982 |
| ACTN1 | actinin, alpha 1 | 0.029367 |
| HPCAL1 | hippocalcin-like 1 | 0.0291076 |
| UTRN | utrophin | 0.028897 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0288311 |
| MED13L | mediator complex subunit 13-like | 0.0287391 |
| HLA-C | major histocompatibility complex, class I, C | 0.0284993 |
| COL5A1 | collagen, type V, alpha 1 | 0.0278476 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0277908 |
| FUS | FUS RNA binding protein | 0.0277201 |
| KIAA1217 | KIAA1217 | 0.0273789 |
| THBS1 | thrombospondin 1 | 0.0273323 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0267322 |
| KYNU | kynureninase | 0.0265732 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.026482 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0263869 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0260751 |
| PCBP3 | poly(rC) binding protein 3 | 0.0257671 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0254684 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0253503 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0250433 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0250082 |
| MYO9B | myosin IXB | 0.0246887 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0246684 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0243162 |
| AOPEP | aminopeptidase O (putative) | 0.0242307 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0241497 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.024135 |
| PLEC | plectin | 0.0240033 |
| ZNF217 | zinc finger protein 217 | 0.023906 |
| PTMA | prothymosin, alpha | 0.0237601 |
| SVIL | supervillin | 0.0237251 |
| CPNE1 | copine I | 0.0231773 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.0228493 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0226199 |
| SKI | SKI proto-oncogene | 0.0226175 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0226054 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0225758 |
| PRKCE | protein kinase C, epsilon | 0.0225227 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0224769 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0224681 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0223666 |
| TNNC1 | troponin C type 1 (slow) | 0.0221764 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0221706 |
| SMOX | spermine oxidase | 0.0220808 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0220465 |
| MOCOS | molybdenum cofactor sulfurase | 0.0219818 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0219638 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.021912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.130262 |
| STC1 | stanniocalcin 1 | -0.129913 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.125118 |
| MT2A | metallothionein 2A | -0.107224 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0873934 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0702875 |
| LDHA | lactate dehydrogenase A | -0.0647082 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0646517 |
| ANGPTL4 | angiopoietin-like 4 | -0.0631676 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0607363 |
| VEGFA | vascular endothelial growth factor A | -0.0598516 |
| VIM | vimentin | -0.0585797 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0577366 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0550823 |
| B2M | beta-2-microglobulin | -0.0539703 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0538389 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0501813 |
| FTL | ferritin, light polypeptide | -0.04828 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.047053 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0467871 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0449406 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0436101 |
| ZNF292 | zinc finger protein 292 | -0.0425809 |
| CDCP1 | CUB domain containing protein 1 | -0.0398781 |
| RPS19 | ribosomal protein S19 | -0.0379643 |
| TMSB10 | thymosin beta 10 | -0.0364836 |
| PKM | pyruvate kinase, muscle | -0.0358566 |
| RPS6 | ribosomal protein S6 | -0.0351335 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0349196 |
| CENPF | centromere protein F, 350/400kDa | -0.0335095 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0315429 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0310654 |
| RPS3 | ribosomal protein S3 | -0.030848 |
| RNF24 | ring finger protein 24 | -0.0307726 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0281904 |
| FAM162A | family with sequence similarity 162, member A | -0.027703 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0270932 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.026885 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0266711 |
| TGM2 | transglutaminase 2 | -0.02664 |
| MTSS1 | metastasis suppressor 1 | -0.026557 |
| RPS12 | ribosomal protein S12 | -0.0265017 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0264687 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0262713 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0262639 |
| MMP12 | matrix metallopeptidase 12 | -0.0260039 |
| IFI44L | interferon-induced protein 44-like | -0.0252526 |
| SEC24A | SEC24 family member A | -0.0251473 |
| GOLGA4 | golgin A4 | -0.0250423 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0250065 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0243058 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0242001 |
| TNS3 | tensin 3 | -0.0240912 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0235811 |
| RPS17 | ribosomal protein S17 | -0.0235427 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0233439 |
| BBX | bobby sox homolog (Drosophila) | -0.0233322 |
| RPL23 | ribosomal protein L23 | -0.0232398 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0231404 |
| INSIG2 | insulin induced gene 2 | -0.0230536 |
| SRP54 | signal recognition particle 54kDa | -0.0229592 |
| C1R | complement component 1, r subcomponent | -0.0227975 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0223239 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0222522 |
| RACK1 | receptor for activated C kinase 1 | -0.022177 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.022123 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0215514 |
| CDH13 | cadherin 13 | -0.0212933 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0212328 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212225 |
| PGK1 | phosphoglycerate kinase 1 | -0.0210459 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0209512 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0208627 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0208088 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0206861 |
| FNBP4 | formin binding protein 4 | -0.0206451 |
| DTNA | dystrobrevin, alpha | -0.0206189 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0204238 |
| FAM13A | family with sequence similarity 13, member A | -0.0204142 |
| RPL37A | ribosomal protein L37a | -0.0202766 |
| CADM1 | cell adhesion molecule 1 | -0.0202632 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0202188 |
| RAD51B | RAD51 paralog B | -0.0201609 |
| DENND1A | DENN/MADD domain containing 1A | -0.0199469 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0199281 |
| CCNL1 | cyclin L1 | -0.0198831 |
| FBXO42 | F-box protein 42 | -0.0198268 |
| DEPP1 | DEPP autophagy regulator 1 | -0.019759 |
| SETD5 | SET domain containing 5 | -0.0194787 |
| RPL36 | ribosomal protein L36 | -0.0194046 |
| PDGFC | platelet derived growth factor C | -0.0193556 |
| ZNF148 | zinc finger protein 148 | -0.0189846 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0187515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0187426 |
| PHF21A | PHD finger protein 21A | -0.0186337 |
| YBX1 | Y box binding protein 1 | -0.0185866 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0184245 |
| GOLGB1 | golgin B1 | -0.018328 |
| HLA-A | major histocompatibility complex, class I, A | -0.0183133 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0179983 |
