| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119244 |
| MCL1 | myeloid cell leukemia 1 | 0.0852634 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0587194 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0511659 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0474168 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0444801 |
| HOMER1 | homer scaffolding protein 1 | 0.0437622 |
| NDRG1 | N-myc downstream regulated 1 | 0.0406822 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0356162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0327218 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0316189 |
| CHGB | chromogranin B | 0.0312268 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0307694 |
| VEGFA | vascular endothelial growth factor A | 0.0293662 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0293591 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.029042 |
| SVIL | supervillin | 0.0290211 |
| ASPH | aspartate beta-hydroxylase | 0.0284917 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0272688 |
| LRATD1 | LRAT domain containing 1 | 0.0271564 |
| EP400 | E1A binding protein p400 | 0.0270849 |
| NANOS1 | nanos homolog 1 (Drosophila) | 0.0270599 |
| LRFN2 | leucine rich repeat and fibronectin type III domain containing 2 | 0.0256528 |
| KLHL29 | kelch-like family member 29 | 0.025222 |
| KIF26B | kinesin family member 26B | 0.0250788 |
| NAV2 | neuron navigator 2 | 0.0249351 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0247416 |
| RNF213 | ring finger protein 213 | 0.0244137 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0241882 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0238944 |
| HYOU1 | hypoxia up-regulated 1 | 0.0235211 |
| SMAD3 | SMAD family member 3 | 0.02211 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0219237 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0216304 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0216084 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0210802 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.0209138 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0205957 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0202681 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0202264 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0201155 |
| TOP1 | topoisomerase (DNA) I | 0.0200562 |
| TJP1 | tight junction protein 1 | 0.0197974 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0197851 |
| SETX | senataxin | 0.0197448 |
| WLS | wntless Wnt ligand secretion mediator | 0.019571 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0194608 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.019425 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0191796 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0191039 |
| MSN | moesin | 0.0190141 |
| FLNB | filamin B, beta | 0.0189231 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0188687 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0187807 |
| POTEF | POTE ankyrin domain family, member F | 0.0185935 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0185725 |
| DENND1A | DENN/MADD domain containing 1A | 0.0185625 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0184289 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.018252 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | 0.0181561 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0180412 |
| ANO6 | anoctamin 6 | 0.0180372 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0180247 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0180074 |
| DUSP10 | dual specificity phosphatase 10 | 0.0179167 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0178543 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0178178 |
| RIGI | RNA sensor RIG-I | 0.0175888 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0174952 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0174122 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0173141 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0168757 |
| FLNA | filamin A, alpha | 0.0167515 |
| NUP58 | nucleoporin 58 | 0.0165542 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0164708 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.016459 |
| CCNY | cyclin Y | 0.0164004 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0163577 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0162071 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0161689 |
| LPIN1 | lipin 1 | 0.0161086 |
| EGFR | epidermal growth factor receptor | 0.0160425 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0159241 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0158037 |
| GRB10 | growth factor receptor-bound protein 10 | 0.015777 |
| EPHA4 | EPH receptor A4 | 0.015751 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0155278 |
| TUSC3 | tumor suppressor candidate 3 | 0.0154935 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0153755 |
| SCG2 | secretogranin II | 0.0152251 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0150845 |
| NUP98 | nucleoporin 98kDa | 0.0150409 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0149673 |
| VCL | vinculin | 0.0149586 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0149362 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0148683 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0148606 |
| FAM120A | family with sequence similarity 120A | 0.014828 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0146892 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0145273 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.200287 |
| PTMA | prothymosin, alpha | -0.146292 |
| PEG10 | paternally expressed 10 | -0.118951 |
| ENO1 | enolase 1, (alpha) | -0.102763 |
| MT2A | metallothionein 2A | -0.0877475 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0775553 |
| RPS3 | ribosomal protein S3 | -0.0740942 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0721143 |
| PDE10A | phosphodiesterase 10A | -0.0699028 |
| SYT1 | synaptotagmin I | -0.064903 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0624479 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0603545 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0572989 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0567495 |
| RPL26 | ribosomal protein L26 | -0.0537261 |
| SNTG1 | syntrophin, gamma 1 | -0.0533414 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0516275 |
| RIT2 | Ras-like without CAAX 2 | -0.051032 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500386 |
| RPL37 | ribosomal protein L37 | -0.049714 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0493404 |
| FTL | ferritin, light polypeptide | -0.0479964 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0475076 |
| CENPF | centromere protein F, 350/400kDa | -0.0470268 |
| PGK1 | phosphoglycerate kinase 1 | -0.0464616 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0464317 |
| FOXC1 | forkhead box C1 | -0.046089 |
| MKI67 | marker of proliferation Ki-67 | -0.0460323 |
| SET | SET nuclear proto-oncogene | -0.0457352 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0445704 |
| STC1 | stanniocalcin 1 | -0.0442748 |
| GPC6 | glypican 6 | -0.0440554 |
| TMSB4X | thymosin beta 4, X-linked | -0.0433851 |
| RPL37A | ribosomal protein L37a | -0.0431433 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0430703 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.042588 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0417951 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0415104 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.041217 |
| NFIA | nuclear factor I/A | -0.040516 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0402617 |
| MAP1B | microtubule-associated protein 1B | -0.0402587 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0391991 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0386586 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0386098 |
| RPL4 | ribosomal protein L4 | -0.0382377 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0379111 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0372639 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0366466 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0364836 |
| FGF14 | fibroblast growth factor 14 | -0.03595 |
| RBM25 | RNA binding motif protein 25 | -0.0350761 |
| DTNA | dystrobrevin, alpha | -0.0348471 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0341481 |
| LDHA | lactate dehydrogenase A | -0.0340341 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0339869 |
| PCDH9 | protocadherin 9 | -0.0338488 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0335086 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0332582 |
| STXBP5L | syntaxin binding protein 5-like | -0.0331341 |
| TENM1 | teneurin transmembrane protein 1 | -0.032518 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0322895 |
| RPS12 | ribosomal protein S12 | -0.0317971 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.031601 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0313537 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0307237 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0306748 |
| SCG3 | secretogranin III | -0.0306114 |
| RACK1 | receptor for activated C kinase 1 | -0.0305791 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0302734 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0300254 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0300046 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0297699 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0292723 |
| TPR | translocated promoter region, nuclear basket protein | -0.0292394 |
| CNKSR3 | CNKSR family member 3 | -0.0290393 |
| RPL19 | ribosomal protein L19 | -0.0290269 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0289443 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0288911 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0288563 |
| AGBL4 | ATP/GTP binding protein-like 4 | -0.0285395 |
| RPL11 | ribosomal protein L11 | -0.0283207 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0281327 |
| RPL23 | ribosomal protein L23 | -0.0280748 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0278863 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0277774 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0275959 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0275454 |
| KIAA0825 | KIAA0825 | -0.0275372 |
| H1-0 | H1.0 linker histone | -0.0274081 |
| SGO2 | shugoshin 2 | -0.0271151 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0270806 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0270641 |
| ZFR | zinc finger RNA binding protein | -0.0270342 |
| ESRRG | estrogen-related receptor gamma | -0.0269878 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0269472 |
| HMGB2 | high mobility group box 2 | -0.0269285 |
| JAZF1 | JAZF zinc finger 1 | -0.0268827 |
| AOPEP | aminopeptidase O (putative) | -0.0267789 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0264806 |
