| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.116527 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0575918 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0483443 |
| TXNRD1 | thioredoxin reductase 1 | 0.0384324 |
| NAV2 | neuron navigator 2 | 0.0375632 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0356798 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305851 |
| CD44 | CD44 molecule (Indian blood group) | 0.0286387 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0283568 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270682 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0267389 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0244945 |
| FLNA | filamin A, alpha | 0.0242369 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0229864 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0228513 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0227706 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.022316 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022303 |
| MSN | moesin | 0.0213953 |
| ATP13A3 | ATPase type 13A3 | 0.0209984 |
| AFDN | afadin, adherens junction formation factor | 0.0209139 |
| EMP1 | epithelial membrane protein 1 | 0.0208088 |
| TPM3 | tropomyosin 3 | 0.0204343 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0202611 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0201105 |
| PLEC | plectin | 0.0197917 |
| AHNAK | AHNAK nucleoprotein | 0.0195241 |
| RASAL2 | RAS protein activator like 2 | 0.0195149 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0194727 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0189391 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0188331 |
| FAM219A | family with sequence similarity 219, member A | 0.0182918 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0181663 |
| CEP128 | centrosomal protein 128kDa | 0.0177652 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0173998 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0171748 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0169904 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.01695 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0168933 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.016598 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.016503 |
| PCBP3 | poly(rC) binding protein 3 | 0.0164411 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0160073 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0159397 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0159381 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0158042 |
| CORO1C | coronin, actin binding protein, 1C | 0.0156815 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.015575 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0152868 |
| MCL1 | myeloid cell leukemia 1 | 0.0150163 |
| TLN1 | talin 1 | 0.0147285 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0147007 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | 0.0146591 |
| ATXN1 | ataxin 1 | 0.0145877 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0143649 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0142924 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0141853 |
| CENPF | centromere protein F, 350/400kDa | 0.0139926 |
| ATF6 | activating transcription factor 6 | 0.0138594 |
| DIAPH1 | diaphanous-related formin 1 | 0.0138061 |
| RPL3 | ribosomal protein L3 | 0.0136626 |
| ANLN | anillin, actin binding protein | 0.0134875 |
| INTS6 | integrator complex subunit 6 | 0.0134816 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0134471 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0130578 |
| STK4 | serine/threonine kinase 4 | 0.0129769 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0129574 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0126028 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.012509 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0124473 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0123671 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0122651 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0122397 |
| SETX | senataxin | 0.0122122 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0121806 |
| KIF1B | kinesin family member 1B | 0.0121755 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0121267 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0120873 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0120376 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0120331 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0119621 |
| ZNF800 | zinc finger protein 800 | 0.0118287 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0118123 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.011589 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0115138 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0114391 |
| AMOTL1 | angiomotin like 1 | 0.0113278 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0111787 |
| RCC1 | regulator of chromosome condensation 1 | 0.0111621 |
| RASA2 | RAS p21 protein activator 2 | 0.0111254 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0110958 |
| FRYL | FRY-like | 0.0110259 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0110185 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0109801 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0109591 |
| NAV1 | neuron navigator 1 | 0.0109173 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0108307 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0107806 |
| CTNNBL1 | catenin, beta like 1 | 0.0107414 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0107259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.244209 |
| FN1 | fibronectin 1 | -0.216816 |
| LSAMP | limbic system-associated membrane protein | -0.206845 |
| NRG3 | neuregulin 3 | -0.185177 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.15535 |
| FNDC3B | fibronectin type III domain containing 3B | -0.125954 |
| NLGN1 | neuroligin 1 | -0.122375 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103822 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0789398 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0692769 |
| FRMD4A | FERM domain containing 4A | -0.0689127 |
| FHIT | fragile histidine triad | -0.0679676 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0647129 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0647124 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0618899 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0596776 |
| MSI2 | musashi RNA-binding protein 2 | -0.0593729 |
| RPL35A | ribosomal protein L35a | -0.0554856 |
| FTL | ferritin, light polypeptide | -0.054237 |
| TMSB10 | thymosin beta 10 | -0.053922 |
| CADM1 | cell adhesion molecule 1 | -0.0530683 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0524257 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0509594 |
| PTMA | prothymosin, alpha | -0.0502492 |
| GOLGA4 | golgin A4 | -0.0477678 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.046073 |
| FMNL2 | formin-like 2 | -0.0445884 |
| PMEL | premelanosome protein | -0.0436073 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.043313 |
| TNNC1 | troponin C type 1 (slow) | -0.0415587 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0407851 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0406336 |
| INPP5F | inositol polyphosphate-5-phosphatase F | -0.0400593 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0392227 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0384388 |
| MT2A | metallothionein 2A | -0.0383682 |
| LDHA | lactate dehydrogenase A | -0.0378798 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0377827 |
| RPS6 | ribosomal protein S6 | -0.0367906 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0356067 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0349891 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0341679 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0339335 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0338533 |
| SBF2 | SET binding factor 2 | -0.0338533 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0332656 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332495 |
| SETD5 | SET domain containing 5 | -0.0330771 |
| HMGA1 | high mobility group AT-hook 1 | -0.0328359 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0326616 |
| CNKSR3 | CNKSR family member 3 | -0.0316619 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0315755 |
| RPS3 | ribosomal protein S3 | -0.0310741 |
| JMJD1C | jumonji domain containing 1C | -0.0309694 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0306075 |
| APOD | apolipoprotein D | -0.0305884 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0305604 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0303477 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0302046 |
| PRAME | preferentially expressed antigen in melanoma | -0.0299992 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0287856 |
| NF1 | neurofibromin 1 | -0.0287178 |
| MT1X | metallothionein 1X | -0.0286921 |
| EHBP1 | EH domain binding protein 1 | -0.0284908 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282743 |
| WDR45B | WD repeat domain 45B | -0.028259 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0281657 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0277053 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0267806 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0267135 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0264637 |
| SQSTM1 | sequestosome 1 | -0.0264352 |
| CBX3 | chromobox homolog 3 | -0.0260244 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0257581 |
| IGF1R | insulin-like growth factor 1 receptor | -0.025716 |
| FRMD5 | FERM domain containing 5 | -0.0257157 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0255792 |
| RAD51B | RAD51 paralog B | -0.025555 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0252227 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0251973 |
| RPL34 | ribosomal protein L34 | -0.0250025 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0248422 |
| TPI1 | triosephosphate isomerase 1 | -0.024702 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0246655 |
| RNF145 | ring finger protein 145 | -0.0245209 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0240132 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0238703 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | -0.0237596 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0235704 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.023482 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.023477 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0233522 |
| S100A6 | S100 calcium binding protein A6 | -0.0232968 |
| ACTG1 | actin gamma 1 | -0.0231401 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0229868 |
| MEF2A | myocyte enhancer factor 2A | -0.0229364 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0229267 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0229023 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0228532 |
| CDK6 | cyclin-dependent kinase 6 | -0.0227719 |
