| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.163526 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.125775 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.117423 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.112395 |
| NAV2 | neuron navigator 2 | 0.104035 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0878082 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0838087 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0813095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0808398 |
| CADM1 | cell adhesion molecule 1 | 0.0747152 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0733377 |
| VEGFA | vascular endothelial growth factor A | 0.0683438 |
| CDH13 | cadherin 13 | 0.0623026 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0589552 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.058942 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0587628 |
| FNIP1 | folliculin interacting protein 1 | 0.0560791 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0560383 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0547677 |
| PDE10A | phosphodiesterase 10A | 0.053899 |
| MYOF | myoferlin | 0.0522407 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0517361 |
| SQSTM1 | sequestosome 1 | 0.050592 |
| FLNA | filamin A, alpha | 0.0475375 |
| HDAC9 | histone deacetylase 9 | 0.0475021 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0465332 |
| COL5A1 | collagen, type V, alpha 1 | 0.0451426 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0450979 |
| RND3 | Rho family GTPase 3 | 0.0449202 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0443762 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0441937 |
| PRELID2 | PRELI domain containing 2 | 0.0438857 |
| TNS3 | tensin 3 | 0.042813 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0426804 |
| EGFR | epidermal growth factor receptor | 0.041775 |
| ATXN1 | ataxin 1 | 0.0384874 |
| FMNL2 | formin-like 2 | 0.0380472 |
| MLPH | melanophilin | 0.0378682 |
| DUSP10 | dual specificity phosphatase 10 | 0.0377701 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0374478 |
| GOLGA4 | golgin A4 | 0.0365397 |
| CALR | calreticulin | 0.0356226 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0349197 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344406 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0341769 |
| UBC | ubiquitin C | 0.0341514 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0340299 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0326083 |
| FOXO3 | forkhead box O3 | 0.0324249 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0322107 |
| ADM | adrenomedullin | 0.0320066 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319682 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0317424 |
| INTS6 | integrator complex subunit 6 | 0.031056 |
| SEPTIN9 | septin 9 | 0.0309218 |
| TMEM132D | transmembrane protein 132D | 0.0308508 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0304531 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0299548 |
| FRMD4A | FERM domain containing 4A | 0.0297958 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0297932 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0295843 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0295342 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0294664 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0293057 |
| COL1A1 | collagen, type I, alpha 1 | 0.0291517 |
| PRKCA | protein kinase C, alpha | 0.0288342 |
| MMP12 | matrix metallopeptidase 12 | 0.0288017 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0287932 |
| CANX | calnexin | 0.0283498 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0275257 |
| MSN | moesin | 0.0273866 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0268919 |
| NAV1 | neuron navigator 1 | 0.0266143 |
| FLNB | filamin B, beta | 0.0265273 |
| DST | dystonin | 0.0264959 |
| SLC35F3 | solute carrier family 35, member F3 | 0.026429 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0263745 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0256434 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0253514 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0251757 |
| ARFGEF3 | ARFGEF family member 3 | 0.0251191 |
| PCBP3 | poly(rC) binding protein 3 | 0.0250346 |
| HELZ | helicase with zinc finger | 0.0248661 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0246937 |
| PTEN | phosphatase and tensin homolog | 0.0246409 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0246385 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0244148 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239749 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0239155 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0237657 |
| FBXO32 | F-box protein 32 | 0.023678 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0233995 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0232627 |
| CTBP2 | C-terminal binding protein 2 | 0.0229246 |
| COPA | coatomer protein complex, subunit alpha | 0.0228351 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0227469 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0227085 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.022611 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0225548 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0225286 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.130396 |
| FTL | ferritin, light polypeptide | -0.110301 |
| BICC1 | BicC family RNA binding protein 1 | -0.101921 |
| MT2A | metallothionein 2A | -0.0925345 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.091205 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0894106 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0879638 |
| GLIS3 | GLIS family zinc finger 3 | -0.084341 |
| VCL | vinculin | -0.0754862 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0740919 |
| PGK1 | phosphoglycerate kinase 1 | -0.0628062 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0611153 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0582955 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0556863 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0547691 |
| TMSB10 | thymosin beta 10 | -0.0532423 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0519014 |
| RPS12 | ribosomal protein S12 | -0.04434 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0426568 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.041633 |
| RACK1 | receptor for activated C kinase 1 | -0.0412541 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0409381 |
| RPL12 | ribosomal protein L12 | -0.0404793 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0385644 |
| MKI67 | marker of proliferation Ki-67 | -0.0384869 |
| B2M | beta-2-microglobulin | -0.0376651 |
| KYNU | kynureninase | -0.0370541 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0361313 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0360142 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0357245 |
| OSMR | oncostatin M receptor | -0.035481 |
| KLF6 | Kruppel-like factor 6 | -0.0345046 |
| HLA-A | major histocompatibility complex, class I, A | -0.0343766 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0341028 |
| RPS6 | ribosomal protein S6 | -0.0340212 |
| RPS3 | ribosomal protein S3 | -0.0331677 |
| RPL19 | ribosomal protein L19 | -0.0329251 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0327361 |
| ANXA2 | annexin A2 | -0.0326211 |
| CDCP1 | CUB domain containing protein 1 | -0.0322732 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322343 |
| RPL37A | ribosomal protein L37a | -0.0320528 |
| HLA-B | major histocompatibility complex, class I, B | -0.0317275 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0314887 |
| GNAS | GNAS complex locus | -0.0312198 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0310084 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.030692 |
| EHBP1 | EH domain binding protein 1 | -0.0304486 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0299645 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0295319 |
| RPL36 | ribosomal protein L36 | -0.0290207 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0289233 |
| RTN4 | reticulon 4 | -0.0287394 |
| FN1 | fibronectin 1 | -0.0287079 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285364 |
| RPL32 | ribosomal protein L32 | -0.0283903 |
| CDK17 | cyclin-dependent kinase 17 | -0.0282217 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0279204 |
| RPL26 | ribosomal protein L26 | -0.0273947 |
| RPS19 | ribosomal protein S19 | -0.0272496 |
| VCAN | versican | -0.0268379 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0267333 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0266108 |
| RIGI | RNA sensor RIG-I | -0.0264221 |
| LDHA | lactate dehydrogenase A | -0.0262537 |
| RPL31 | ribosomal protein L31 | -0.0258432 |
| EGR1 | early growth response 1 | -0.025141 |
| RPL23 | ribosomal protein L23 | -0.0250628 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0249647 |
| CAVIN1 | caveolae associated protein 1 | -0.0249158 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0246092 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0244007 |
| TXNRD1 | thioredoxin reductase 1 | -0.0240964 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0238546 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0237125 |
| ANLN | anillin, actin binding protein | -0.0233164 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0229915 |
| PTMA | prothymosin, alpha | -0.0224017 |
| TUBB | tubulin, beta class I | -0.0223551 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0221438 |
| RPS24 | ribosomal protein S24 | -0.022055 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0217055 |
| TMEM41B | transmembrane protein 41B | -0.0216699 |
| STK17A | serine/threonine kinase 17a | -0.0214363 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0214283 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0210991 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.020747 |
| RPS14 | ribosomal protein S14 | -0.0206591 |
| FAM162A | family with sequence similarity 162, member A | -0.0205597 |
| RPL36A | ribosomal protein L36a | -0.0203551 |
| RPL11 | ribosomal protein L11 | -0.0203412 |
| RPL35 | ribosomal protein L35 | -0.0201466 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0200875 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0197351 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.019723 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0196057 |
| HLA-E | major histocompatibility complex, class I, E | -0.0194205 |
| THBS2 | thrombospondin 2 | -0.0192385 |
| CENPF | centromere protein F, 350/400kDa | -0.0191887 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0191495 |
