S-Adenosyl-L-methionine (disulfate tosylate)_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW 1088 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.163854
NRXN3 neurexin 3 0.0700445
COL5A1 collagen, type V, alpha 1 0.0667867
NAMPT nicotinamide phosphoribosyltransferase 0.0597734
MYH9 myosin, heavy chain 9, non-muscle 0.0537686
SMAD3 SMAD family member 3 0.046403
SOD2 superoxide dismutase 2, mitochondrial 0.0456799
EXT1 exostosin glycosyltransferase 1 0.0446435
AHNAK AHNAK nucleoprotein 0.0414926
NCOR2 nuclear receptor corepressor 2 0.0409777
ERRFI1 ERBB receptor feedback inhibitor 1 0.0376298
GSE1 Gse1 coiled-coil protein 0.036552
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0364203
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0342076
FAM20C family with sequence similarity 20, member C 0.0335332
TRIO trio Rho guanine nucleotide exchange factor 0.0335082
MACF1 microtubule-actin crosslinking factor 1 0.0329228
GLIS3 GLIS family zinc finger 3 0.0326251
ELL2 elongation factor, RNA polymerase II, 2 0.0320781
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0320124
KYNU kynureninase 0.031872
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.031378
SHB Src homology 2 domain containing adaptor protein B 0.0306207
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0304041
ANO6 anoctamin 6 0.0297915
HDLBP high density lipoprotein binding protein 0.0291709
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.0270864
HOOK2 hook microtubule-tethering protein 2 0.0267525
FN1 fibronectin 1 0.0263795
EXOC4 exocyst complex component 4 0.0260281
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0252854
NABP1 nucleic acid binding protein 1 0.0249271
ZNF292 zinc finger protein 292 0.0245795
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.024151
STC1 stanniocalcin 1 0.0240577
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0236167
LOXL2 lysyl oxidase-like 2 0.0232689
UBE2H ubiquitin-conjugating enzyme E2H 0.0231597
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0228215
RNF213 ring finger protein 213 0.0227925
ARRDC3 arrestin domain containing 3 0.0224603
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0220177
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0219501
NIBAN2 niban apoptosis regulator 2 0.0218124
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0214099
JAG1 jagged 1 0.0211707
ZFAND3 zinc finger, AN1-type domain 3 0.0211264
PRKCA protein kinase C, alpha 0.0208115
EPAS1 endothelial PAS domain protein 1 0.0207427
MAP4 microtubule-associated protein 4 0.0205237
PRELID2 PRELI domain containing 2 0.0204418
FBXL7 F-box and leucine-rich repeat protein 7 0.0203294
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.02014
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.0200315
IRAK2 interleukin-1 receptor-associated kinase 2 0.0199468
PDLIM5 PDZ and LIM domain 5 0.0197872
TLN1 talin 1 0.0197124
ATP13A3 ATPase type 13A3 0.0195731
DST dystonin 0.0195449
GRB10 growth factor receptor-bound protein 10 0.0193378
ABLIM3 actin binding LIM protein family, member 3 0.0192977
FRMD6 FERM domain containing 6 0.0188109
AHR aryl hydrocarbon receptor 0.0187467
WNT5A wingless-type MMTV integration site family, member 5A 0.0186781
AUTS2 autism susceptibility candidate 2 0.0185995
RIGI RNA sensor RIG-I 0.018454
ARHGAP35 Rho GTPase activating protein 35 0.018442
COL6A2 collagen, type VI, alpha 2 0.0183936
AOPEP aminopeptidase O (putative) 0.0183472
KDM6A lysine (K)-specific demethylase 6A 0.0183181
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0182623
NAV2 neuron navigator 2 0.0180793
IL6ST interleukin 6 signal transducer 0.0180218
TNS3 tensin 3 0.0177832
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0177052
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0176649
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.017649
PLEC plectin 0.0175534
COL4A2 collagen, type IV, alpha 2 0.0172463
KIAA0319L KIAA0319-like 0.0171231
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0170735
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.017069
GOLGB1 golgin B1 0.0170298
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0170172
FAT1 FAT atypical cadherin 1 0.0169349
FAM219A family with sequence similarity 219, member A 0.0168732
SUCO SUN domain containing ossification factor 0.0167138
BACE2 beta-site APP-cleaving enzyme 2 0.0166502
SMOX spermine oxidase 0.0166159
PRKN parkin RBR E3 ubiquitin protein ligase 0.0165383
MBD5 methyl-CpG binding domain protein 5 0.0164154
ZBTB38 zinc finger and BTB domain containing 38 0.0162741
STK17A serine/threonine kinase 17a 0.0162365
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0162325
BCAR3 breast cancer anti-estrogen resistance 3 0.016205
PPP4R3B protein phosphatase 4 regulatory subunit 3B 0.0162013
ITFG1 integrin alpha FG-GAP repeat containing 1 0.0161341
RUNX1 runt-related transcription factor 1 0.0159962
BTBD9 BTB (POZ) domain containing 9 0.015975
RASA3 RAS p21 protein activator 3 0.0159458

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.229886
MT2A metallothionein 2A -0.214403
VIM vimentin -0.214271
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.135016
FTL ferritin, light polypeptide -0.130982
HLA-B major histocompatibility complex, class I, B -0.119506
TGFBI transforming growth factor, beta-induced, 68kDa -0.0886011
B2M beta-2-microglobulin -0.0818455
IGFBP3 insulin-like growth factor binding protein 3 -0.0786168
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0730701
PTMA prothymosin, alpha -0.0725728
TPT1 tumor protein, translationally-controlled 1 -0.0710144
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0686076
RPS6 ribosomal protein S6 -0.0680869
PKM pyruvate kinase, muscle -0.0672631
NDRG1 N-myc downstream regulated 1 -0.0656286
RPL35A ribosomal protein L35a -0.0605537
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0603929
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0598625
ACTG1 actin gamma 1 -0.0580706
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0555318
POTEF POTE ankyrin domain family, member F -0.0549188
RPS8 ribosomal protein S8 -0.0544178
RPL34 ribosomal protein L34 -0.0517929
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0511833
RPS3 ribosomal protein S3 -0.0493179
RPL23 ribosomal protein L23 -0.0484887
ENO1 enolase 1, (alpha) -0.0478271
EIF1 eukaryotic translation initiation factor 1 -0.0462084
PGK1 phosphoglycerate kinase 1 -0.0452117
RPL11 ribosomal protein L11 -0.0451937
TPM4 tropomyosin 4 -0.0446383
HLA-A major histocompatibility complex, class I, A -0.0413361
PDIA3 protein disulfide isomerase family A, member 3 -0.0399507
RTN4 reticulon 4 -0.0396873
RPL31 ribosomal protein L31 -0.0382716
RPLP1 ribosomal protein, large, P1 -0.0380981
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0380863
RPS19 ribosomal protein S19 -0.0380288
RPS27A ribosomal protein S27a -0.0360606
KTN1 kinectin 1 (kinesin receptor) -0.0359069
DSTN destrin (actin depolymerizing factor) -0.0357296
RPS12 ribosomal protein S12 -0.0353989
ENO2 enolase 2 (gamma, neuronal) -0.0353581
RPL9 ribosomal protein L9 -0.035222
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0350636
RPL37A ribosomal protein L37a -0.034913
S100A9 S100 calcium binding protein A9 -0.0348818
S100A10 S100 calcium binding protein A10 -0.0344784
S100A6 S100 calcium binding protein A6 -0.0342155
RPS14 ribosomal protein S14 -0.0339023
SEPTIN7 septin 7 -0.0337972
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0327256
GLG1 golgi glycoprotein 1 -0.032148
EGFR epidermal growth factor receptor -0.0310948
AKAP12 A kinase (PRKA) anchor protein 12 -0.030794
KDM5B lysine (K)-specific demethylase 5B -0.0306234
PDE4D phosphodiesterase 4D, cAMP-specific -0.0302645
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0296724
HILPDA hypoxia inducible lipid droplet-associated -0.0295152
CALR calreticulin -0.029454
COL6A1 collagen, type VI, alpha 1 -0.0293152
PDIA6 protein disulfide isomerase family A, member 6 -0.0290521
TPM2 tropomyosin 2 (beta) -0.0289997
RPS23 ribosomal protein S23 -0.0289921
TBCA tubulin folding cofactor A -0.0287853
MTDH metadherin -0.02874
RPS13 ribosomal protein S13 -0.0285827
RPS17 ribosomal protein S17 -0.0285395
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0283667
ATF4 activating transcription factor 4 -0.0283554
RPL37 ribosomal protein L37 -0.0278282
GNAS GNAS complex locus -0.0277804
PUM2 pumilio RNA-binding family member 2 -0.0277143
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0271553
RPS25 ribosomal protein S25 -0.0267737
SEC24D SEC24 family member D -0.0267567
ADM adrenomedullin -0.0264395
RPS27 ribosomal protein S27 -0.0263305
IL6 interleukin 6 -0.0262136
CXCL8 chemokine (C-X-C motif) ligand 8 -0.026093
F3 coagulation factor III (thromboplastin, tissue factor) -0.0259638
LMNA lamin A/C -0.0257842
CANX calnexin -0.025567
CCDC88A coiled-coil domain containing 88A -0.0254413
RPS16 ribosomal protein S16 -0.0244948
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0244207
VDAC1 voltage-dependent anion channel 1 -0.0241417
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0240982
RPL12 ribosomal protein L12 -0.0239681
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0238288
RPS11 ribosomal protein S11 -0.0236909
RNF145 ring finger protein 145 -0.0236657
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -0.0235066
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0229077
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0228492
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0225393
KMT2C lysine (K)-specific methyltransferase 2C -0.0224965
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0222746
STC2 stanniocalcin 2 -0.0216569