| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.163854 |
| NRXN3 | neurexin 3 | 0.0700445 |
| COL5A1 | collagen, type V, alpha 1 | 0.0667867 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0597734 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537686 |
| SMAD3 | SMAD family member 3 | 0.046403 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0456799 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0446435 |
| AHNAK | AHNAK nucleoprotein | 0.0414926 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0409777 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0376298 |
| GSE1 | Gse1 coiled-coil protein | 0.036552 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0364203 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0342076 |
| FAM20C | family with sequence similarity 20, member C | 0.0335332 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0335082 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0329228 |
| GLIS3 | GLIS family zinc finger 3 | 0.0326251 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0320781 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0320124 |
| KYNU | kynureninase | 0.031872 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.031378 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0306207 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0304041 |
| ANO6 | anoctamin 6 | 0.0297915 |
| HDLBP | high density lipoprotein binding protein | 0.0291709 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0270864 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0267525 |
| FN1 | fibronectin 1 | 0.0263795 |
| EXOC4 | exocyst complex component 4 | 0.0260281 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0252854 |
| NABP1 | nucleic acid binding protein 1 | 0.0249271 |
| ZNF292 | zinc finger protein 292 | 0.0245795 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024151 |
| STC1 | stanniocalcin 1 | 0.0240577 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236167 |
| LOXL2 | lysyl oxidase-like 2 | 0.0232689 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0231597 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0228215 |
| RNF213 | ring finger protein 213 | 0.0227925 |
| ARRDC3 | arrestin domain containing 3 | 0.0224603 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0220177 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0219501 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0218124 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0214099 |
| JAG1 | jagged 1 | 0.0211707 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0211264 |
| PRKCA | protein kinase C, alpha | 0.0208115 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0207427 |
| MAP4 | microtubule-associated protein 4 | 0.0205237 |
| PRELID2 | PRELI domain containing 2 | 0.0204418 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0203294 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.02014 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0200315 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0199468 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0197872 |
| TLN1 | talin 1 | 0.0197124 |
| ATP13A3 | ATPase type 13A3 | 0.0195731 |
| DST | dystonin | 0.0195449 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0193378 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0192977 |
| FRMD6 | FERM domain containing 6 | 0.0188109 |
| AHR | aryl hydrocarbon receptor | 0.0187467 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0186781 |
| AUTS2 | autism susceptibility candidate 2 | 0.0185995 |
| RIGI | RNA sensor RIG-I | 0.018454 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.018442 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0183936 |
| AOPEP | aminopeptidase O (putative) | 0.0183472 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0183181 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182623 |
| NAV2 | neuron navigator 2 | 0.0180793 |
| IL6ST | interleukin 6 signal transducer | 0.0180218 |
| TNS3 | tensin 3 | 0.0177832 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0177052 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0176649 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.017649 |
| PLEC | plectin | 0.0175534 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0172463 |
| KIAA0319L | KIAA0319-like | 0.0171231 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0170735 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.017069 |
| GOLGB1 | golgin B1 | 0.0170298 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0170172 |
| FAT1 | FAT atypical cadherin 1 | 0.0169349 |
| FAM219A | family with sequence similarity 219, member A | 0.0168732 |
| SUCO | SUN domain containing ossification factor | 0.0167138 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0166502 |
| SMOX | spermine oxidase | 0.0166159 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0165383 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0164154 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0162741 |
| STK17A | serine/threonine kinase 17a | 0.0162365 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0162325 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.016205 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | 0.0162013 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0161341 |
| RUNX1 | runt-related transcription factor 1 | 0.0159962 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.015975 |
| RASA3 | RAS p21 protein activator 3 | 0.0159458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.229886 |
| MT2A | metallothionein 2A | -0.214403 |
| VIM | vimentin | -0.214271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135016 |
| FTL | ferritin, light polypeptide | -0.130982 |
| HLA-B | major histocompatibility complex, class I, B | -0.119506 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0886011 |
| B2M | beta-2-microglobulin | -0.0818455 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0786168 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0730701 |
| PTMA | prothymosin, alpha | -0.0725728 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0710144 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0686076 |
| RPS6 | ribosomal protein S6 | -0.0680869 |
| PKM | pyruvate kinase, muscle | -0.0672631 |
| NDRG1 | N-myc downstream regulated 1 | -0.0656286 |
| RPL35A | ribosomal protein L35a | -0.0605537 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0603929 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0598625 |
| ACTG1 | actin gamma 1 | -0.0580706 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0555318 |
| POTEF | POTE ankyrin domain family, member F | -0.0549188 |
| RPS8 | ribosomal protein S8 | -0.0544178 |
| RPL34 | ribosomal protein L34 | -0.0517929 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0511833 |
| RPS3 | ribosomal protein S3 | -0.0493179 |
| RPL23 | ribosomal protein L23 | -0.0484887 |
| ENO1 | enolase 1, (alpha) | -0.0478271 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0462084 |
| PGK1 | phosphoglycerate kinase 1 | -0.0452117 |
| RPL11 | ribosomal protein L11 | -0.0451937 |
| TPM4 | tropomyosin 4 | -0.0446383 |
| HLA-A | major histocompatibility complex, class I, A | -0.0413361 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0399507 |
| RTN4 | reticulon 4 | -0.0396873 |
| RPL31 | ribosomal protein L31 | -0.0382716 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380981 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0380863 |
| RPS19 | ribosomal protein S19 | -0.0380288 |
| RPS27A | ribosomal protein S27a | -0.0360606 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0359069 |
| DSTN | destrin (actin depolymerizing factor) | -0.0357296 |
| RPS12 | ribosomal protein S12 | -0.0353989 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0353581 |
| RPL9 | ribosomal protein L9 | -0.035222 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0350636 |
| RPL37A | ribosomal protein L37a | -0.034913 |
| S100A9 | S100 calcium binding protein A9 | -0.0348818 |
| S100A10 | S100 calcium binding protein A10 | -0.0344784 |
| S100A6 | S100 calcium binding protein A6 | -0.0342155 |
| RPS14 | ribosomal protein S14 | -0.0339023 |
| SEPTIN7 | septin 7 | -0.0337972 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0327256 |
| GLG1 | golgi glycoprotein 1 | -0.032148 |
| EGFR | epidermal growth factor receptor | -0.0310948 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.030794 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0306234 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0302645 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0296724 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0295152 |
| CALR | calreticulin | -0.029454 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0293152 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0290521 |
| TPM2 | tropomyosin 2 (beta) | -0.0289997 |
| RPS23 | ribosomal protein S23 | -0.0289921 |
| TBCA | tubulin folding cofactor A | -0.0287853 |
| MTDH | metadherin | -0.02874 |
| RPS13 | ribosomal protein S13 | -0.0285827 |
| RPS17 | ribosomal protein S17 | -0.0285395 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0283667 |
| ATF4 | activating transcription factor 4 | -0.0283554 |
| RPL37 | ribosomal protein L37 | -0.0278282 |
| GNAS | GNAS complex locus | -0.0277804 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0277143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0271553 |
| RPS25 | ribosomal protein S25 | -0.0267737 |
| SEC24D | SEC24 family member D | -0.0267567 |
| ADM | adrenomedullin | -0.0264395 |
| RPS27 | ribosomal protein S27 | -0.0263305 |
| IL6 | interleukin 6 | -0.0262136 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.026093 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0259638 |
| LMNA | lamin A/C | -0.0257842 |
| CANX | calnexin | -0.025567 |
| CCDC88A | coiled-coil domain containing 88A | -0.0254413 |
| RPS16 | ribosomal protein S16 | -0.0244948 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0244207 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0241417 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0240982 |
| RPL12 | ribosomal protein L12 | -0.0239681 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0238288 |
| RPS11 | ribosomal protein S11 | -0.0236909 |
| RNF145 | ring finger protein 145 | -0.0236657 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0235066 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0229077 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0228492 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0225393 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0224965 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0222746 |
| STC2 | stanniocalcin 2 | -0.0216569 |