| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0758896 |
| SMYD3 | SET and MYND domain containing 3 | 0.0612124 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0561384 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0558122 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0544553 |
| DST | dystonin | 0.0531323 |
| SMAD3 | SMAD family member 3 | 0.0528294 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0506221 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0506109 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0482162 |
| CPNE1 | copine I | 0.0448885 |
| ATM | ATM serine/threonine kinase | 0.0445191 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0438133 |
| BRD2 | bromodomain containing 2 | 0.0415452 |
| INTS6 | integrator complex subunit 6 | 0.0395617 |
| TPX2 | TPX2, microtubule-associated | 0.0390204 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0383259 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0380964 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0376253 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0374045 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0366224 |
| CALU | calumenin | 0.0364576 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0362671 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0352382 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351605 |
| SQSTM1 | sequestosome 1 | 0.0350932 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0344474 |
| FLNA | filamin A, alpha | 0.0339819 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0338184 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0334897 |
| OGA | O-GlcNAcase | 0.0324548 |
| CENPF | centromere protein F, 350/400kDa | 0.0318886 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0309772 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0309165 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0305265 |
| PLEC | plectin | 0.0301302 |
| KIF5B | kinesin family member 5B | 0.0300675 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0298758 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0296244 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0293462 |
| TLE4 | transducin-like enhancer of split 4 | 0.028932 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0289251 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0288533 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0286827 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0283667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0278649 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0278577 |
| YAP1 | Yes-associated protein 1 | 0.0276803 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0276725 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0273934 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0273699 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0271344 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0268638 |
| DIAPH1 | diaphanous-related formin 1 | 0.0268235 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.026622 |
| NAV2 | neuron navigator 2 | 0.0266096 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0264545 |
| RBM39 | RNA binding motif protein 39 | 0.0262205 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0262134 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0261396 |
| SEPTIN9 | septin 9 | 0.0259455 |
| NKTR | natural killer cell triggering receptor | 0.0259088 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253634 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0253415 |
| TXNRD1 | thioredoxin reductase 1 | 0.0251692 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0251561 |
| PMM2 | phosphomannomutase 2 | 0.0251388 |
| IL6ST | interleukin 6 signal transducer | 0.0251 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0249594 |
| ANLN | anillin, actin binding protein | 0.0248685 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0245914 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.02423 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0239456 |
| RRBP1 | ribosome binding protein 1 | 0.0239162 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0238774 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0238678 |
| NCKAP1 | NCK-associated protein 1 | 0.0238359 |
| MED13L | mediator complex subunit 13-like | 0.0237951 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0237493 |
| CKAP5 | cytoskeleton associated protein 5 | 0.023646 |
| RUNX1 | runt-related transcription factor 1 | 0.0234691 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.023428 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0234024 |
| TRIM44 | tripartite motif containing 44 | 0.0232968 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0232079 |
| CEP250 | centrosomal protein 250kDa | 0.0229949 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229919 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0225331 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0222874 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.022138 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0220492 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0220335 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0219564 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.021894 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0218915 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0217748 |
| SDC4 | syndecan 4 | 0.0217125 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0216618 |
| MEMO1 | mediator of cell motility 1 | 0.0215288 |
| GAN | gigaxonin | 0.021441 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.306178 |
| VIM | vimentin | -0.1908 |
| TMSB10 | thymosin beta 10 | -0.171906 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.118751 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0923764 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0922716 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0884174 |
| PTMA | prothymosin, alpha | -0.0823658 |
| LDHA | lactate dehydrogenase A | -0.0820537 |
| MT2A | metallothionein 2A | -0.0730669 |
| RPLP1 | ribosomal protein, large, P1 | -0.0693098 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0685729 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0646574 |
| NDRG1 | N-myc downstream regulated 1 | -0.0610316 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0604574 |
| RPL35A | ribosomal protein L35a | -0.0564432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0536791 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0526816 |
| IER3 | immediate early response 3 | -0.0462526 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0456093 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0436699 |
| B2M | beta-2-microglobulin | -0.043607 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0431414 |
| HLA-B | major histocompatibility complex, class I, B | -0.0419251 |
| ANGPTL4 | angiopoietin-like 4 | -0.0415508 |
| S100A9 | S100 calcium binding protein A9 | -0.0404454 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0399596 |
| FTL | ferritin, light polypeptide | -0.0394704 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0380114 |
| RPL23 | ribosomal protein L23 | -0.0379982 |
| PFN1 | profilin 1 | -0.0364922 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0362084 |
| ANXA2 | annexin A2 | -0.0359985 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.035734 |
| HLA-C | major histocompatibility complex, class I, C | -0.0337649 |
| RPS12 | ribosomal protein S12 | -0.0333289 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0332168 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0332083 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.033011 |
| RPS6 | ribosomal protein S6 | -0.032861 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0322392 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0319476 |
| H3-3B | H3.3 histone B | -0.0319189 |
| RACK1 | receptor for activated C kinase 1 | -0.0315839 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0315455 |
| BPTF | bromodomain PHD finger transcription factor | -0.0307538 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0306863 |
| RPS27A | ribosomal protein S27a | -0.0306042 |
| S100A10 | S100 calcium binding protein A10 | -0.0303397 |
| OSMR | oncostatin M receptor | -0.0300164 |
| MAP1B | microtubule-associated protein 1B | -0.0295536 |
| RPL32 | ribosomal protein L32 | -0.0294138 |
| EGR1 | early growth response 1 | -0.0293197 |
| S100A6 | S100 calcium binding protein A6 | -0.0286507 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.028556 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0285026 |
| RPS8 | ribosomal protein S8 | -0.0283244 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0283122 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0283011 |
| PKM | pyruvate kinase, muscle | -0.0282963 |
| RPL34 | ribosomal protein L34 | -0.0282209 |
| RPL37A | ribosomal protein L37a | -0.0272819 |
| RPS14 | ribosomal protein S14 | -0.0267452 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0261065 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0260698 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0259729 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0258288 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0256894 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0255571 |
| MTDH | metadherin | -0.0251799 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0245967 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0245842 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0245162 |
| FMN1 | formin 1 | -0.0245133 |
| RPL26 | ribosomal protein L26 | -0.0245112 |
| TPI1 | triosephosphate isomerase 1 | -0.0244339 |
| TPM4 | tropomyosin 4 | -0.0242713 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0239712 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0239114 |
| HLA-A | major histocompatibility complex, class I, A | -0.0238366 |
| DNER | delta/notch-like EGF repeat containing | -0.0238151 |
| RPS13 | ribosomal protein S13 | -0.0234492 |
| RPL30 | ribosomal protein L30 | -0.0233258 |
| PARD3 | par-3 family cell polarity regulator | -0.0231804 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0230585 |
| FAM193A | family with sequence similarity 193, member A | -0.0229341 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0229229 |
| RAI14 | retinoic acid induced 14 | -0.0228998 |
| BSG | basigin (Ok blood group) | -0.0228986 |
| RPL12 | ribosomal protein L12 | -0.0227391 |
| KLHL5 | kelch-like family member 5 | -0.0227379 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0226924 |
| FAM13A | family with sequence similarity 13, member A | -0.022664 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.022465 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0223623 |
| CBX3 | chromobox homolog 3 | -0.0221914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0221737 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0219409 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.021889 |
| ZNF148 | zinc finger protein 148 | -0.0218739 |
