| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.070263 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481626 |
| NTN4 | netrin 4 | 0.0444772 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0410345 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0400297 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0385377 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375619 |
| FLNA | filamin A, alpha | 0.0370349 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0368373 |
| TOP1 | topoisomerase (DNA) I | 0.0344568 |
| SEPTIN9 | septin 9 | 0.033866 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0321057 |
| CORO1C | coronin, actin binding protein, 1C | 0.0314063 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0303451 |
| PELO | pelota homolog (Drosophila) | 0.0293676 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0282671 |
| SMAD3 | SMAD family member 3 | 0.0282327 |
| WDR1 | WD repeat domain 1 | 0.02809 |
| PLEC | plectin | 0.0261242 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.025921 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0255192 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0251889 |
| TUFT1 | tuftelin 1 | 0.0248396 |
| PALLD | palladin, cytoskeletal associated protein | 0.0246453 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0227382 |
| RIGI | RNA sensor RIG-I | 0.0224301 |
| ACTN4 | actinin, alpha 4 | 0.0213918 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0209654 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0209562 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0203402 |
| RUNX1 | runt-related transcription factor 1 | 0.0202024 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0200693 |
| USP12 | ubiquitin specific peptidase 12 | 0.0196154 |
| FHL2 | four and a half LIM domains 2 | 0.0190519 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0190283 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.018939 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0186464 |
| INTS6 | integrator complex subunit 6 | 0.0183876 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0183524 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0182546 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0181117 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0178916 |
| ATXN1 | ataxin 1 | 0.0176292 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0175086 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0174697 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0171591 |
| DUSP16 | dual specificity phosphatase 16 | 0.0170976 |
| RNF213 | ring finger protein 213 | 0.0170161 |
| KIAA1217 | KIAA1217 | 0.0168464 |
| IL6ST | interleukin 6 signal transducer | 0.0167671 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0167333 |
| ACTN1 | actinin, alpha 1 | 0.0166478 |
| NXN | nucleoredoxin | 0.0166457 |
| TJP1 | tight junction protein 1 | 0.0165595 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0164756 |
| FAT1 | FAT atypical cadherin 1 | 0.0163425 |
| MLPH | melanophilin | 0.0160272 |
| WDR26 | WD repeat domain 26 | 0.0157262 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0156833 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0155811 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0154933 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0154418 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0153359 |
| MYO10 | myosin X | 0.0153152 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0153114 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0151901 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0151224 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0149687 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0149362 |
| AHNAK | AHNAK nucleoprotein | 0.0146163 |
| YAP1 | Yes-associated protein 1 | 0.0145694 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0144558 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0143559 |
| TUSC3 | tumor suppressor candidate 3 | 0.0143141 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0138922 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0137907 |
| ANLN | anillin, actin binding protein | 0.013773 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0137067 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0136816 |
| NPTN | neuroplastin | 0.0136763 |
| STK24 | serine/threonine kinase 24 | 0.0132662 |
| MSN | moesin | 0.0131909 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0131539 |
| ABI1 | abl-interactor 1 | 0.0131455 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0130876 |
| OGA | O-GlcNAcase | 0.0130785 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0130639 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0130627 |
| IFI44 | interferon-induced protein 44 | 0.0130472 |
| SDC2 | syndecan 2 | 0.0129804 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0128698 |
| SEPTIN7 | septin 7 | 0.0128036 |
| XPO1 | exportin 1 | 0.0126492 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0125764 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0125728 |
| JAG1 | jagged 1 | 0.0125477 |
| NCKAP1 | NCK-associated protein 1 | 0.0123917 |
| YBX3 | Y box binding protein 3 | 0.0123813 |
| CCNYL1 | cyclin Y-like 1 | 0.0123224 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.012322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.266774 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.230731 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.187278 |
| NRG1 | neuregulin 1 | -0.174181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.138167 |
| PTMA | prothymosin, alpha | -0.124265 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.122651 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.113115 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0992515 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0899315 |
| HMGA2 | high mobility group AT-hook 2 | -0.0878332 |
| NDRG1 | N-myc downstream regulated 1 | -0.0813982 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0811232 |
| RAI14 | retinoic acid induced 14 | -0.0805639 |
| STC2 | stanniocalcin 2 | -0.0791802 |
| TXNIP | thioredoxin interacting protein | -0.0759843 |
| CANX | calnexin | -0.0751991 |
| TMSB4X | thymosin beta 4, X-linked | -0.0751126 |
| TMSB10 | thymosin beta 10 | -0.0749955 |
| PLIN2 | perilipin 2 | -0.0747446 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0693244 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0685348 |
| SQSTM1 | sequestosome 1 | -0.0668074 |
| HLA-B | major histocompatibility complex, class I, B | -0.0651534 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0638229 |
| GLIS3 | GLIS family zinc finger 3 | -0.0633858 |
| ITGA1 | integrin, alpha 1 | -0.0629974 |
| S100A6 | S100 calcium binding protein A6 | -0.0600834 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0591001 |
| VIM | vimentin | -0.0588907 |
| FTL | ferritin, light polypeptide | -0.0588617 |
| TMEM165 | transmembrane protein 165 | -0.0570082 |
| EFNA5 | ephrin-A5 | -0.0566593 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0563861 |
| CALR | calreticulin | -0.0562032 |
| ENO1 | enolase 1, (alpha) | -0.0560884 |
| VEGFA | vascular endothelial growth factor A | -0.0538163 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.052336 |
| PKM | pyruvate kinase, muscle | -0.0522301 |
| SFTPA2 | surfactant protein A2 | -0.0520258 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0518804 |
| TPR | translocated promoter region, nuclear basket protein | -0.0494791 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0494272 |
| B2M | beta-2-microglobulin | -0.048334 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0482278 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0473515 |
| LMNA | lamin A/C | -0.0469713 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0464775 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0450615 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0446179 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0444194 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.043233 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.043209 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0428775 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0428764 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0417046 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0409373 |
| CD109 | CD109 molecule | -0.0405077 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0394374 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0350513 |
| AHR | aryl hydrocarbon receptor | -0.0349245 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034756 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0344445 |
| SYT1 | synaptotagmin I | -0.0343476 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.034055 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0339778 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0337692 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0337429 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0332983 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327143 |
| TNS3 | tensin 3 | -0.0324757 |
| GLUL | glutamate-ammonia ligase | -0.032032 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0317181 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0316588 |
| USP34 | ubiquitin specific peptidase 34 | -0.0314364 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0312587 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0305509 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0303166 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0300009 |
| RPS27 | ribosomal protein S27 | -0.0298326 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0297729 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294621 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0289844 |
| HMGA1 | high mobility group AT-hook 1 | -0.028827 |
| HLA-A | major histocompatibility complex, class I, A | -0.028773 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0287637 |
| RND3 | Rho family GTPase 3 | -0.0287226 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0283069 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281757 |
| SUCO | SUN domain containing ossification factor | -0.0280737 |
| MYADM | myeloid-associated differentiation marker | -0.027862 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0276056 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0272904 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0271466 |
| RUNX2 | runt-related transcription factor 2 | -0.027028 |
| HDGF | hepatoma-derived growth factor | -0.0269948 |
| TPI1 | triosephosphate isomerase 1 | -0.0269837 |
| GOLGA4 | golgin A4 | -0.026623 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.026493 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0264556 |
