| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.0858027 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.076131 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0617232 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0488277 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0422981 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0417244 |
| VCL | vinculin | 0.0414901 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0412991 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384472 |
| LAMB3 | laminin, beta 3 | 0.037128 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0348894 |
| ACTG1 | actin gamma 1 | 0.034427 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0335732 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0297286 |
| FLOT1 | flotillin 1 | 0.0296449 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0293243 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0290975 |
| RPS27A | ribosomal protein S27a | 0.0290203 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0273791 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0260254 |
| LAMC2 | laminin, gamma 2 | 0.0254756 |
| CDK13 | cyclin-dependent kinase 13 | 0.0249976 |
| KLC1 | kinesin light chain 1 | 0.0240499 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0237749 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0231903 |
| FERMT1 | fermitin family member 1 | 0.0229027 |
| ABR | active BCR-related | 0.0228221 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0223552 |
| RPL13A | ribosomal protein L13a | 0.0222805 |
| FRMD8 | FERM domain containing 8 | 0.0220004 |
| MYO1D | myosin ID | 0.0218708 |
| SEPTIN9 | septin 9 | 0.0218277 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0212329 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0212134 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0209491 |
| RPS29 | ribosomal protein S29 | 0.0206302 |
| MYO5B | myosin VB | 0.0205514 |
| RPS25 | ribosomal protein S25 | 0.0203833 |
| RPS23 | ribosomal protein S23 | 0.0203415 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0202049 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0201257 |
| PLEC | plectin | 0.0199833 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0199244 |
| HDAC4 | histone deacetylase 4 | 0.0197651 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0196417 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0195546 |
| COMMD10 | COMM domain containing 10 | 0.0195442 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0194991 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0194509 |
| ATL2 | atlastin GTPase 2 | 0.0192971 |
| STK4 | serine/threonine kinase 4 | 0.0191331 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0190716 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0188238 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0187824 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.0185373 |
| RPL7A | ribosomal protein L7a | 0.018443 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0183151 |
| LYST | lysosomal trafficking regulator | 0.01823 |
| CUX1 | cut-like homeobox 1 | 0.0182209 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0181703 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0181192 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0179907 |
| GOLGB1 | golgin B1 | 0.0179686 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.017722 |
| EXOC6B | exocyst complex component 6B | 0.0177096 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0176128 |
| EFNB2 | ephrin-B2 | 0.0174843 |
| RPL38 | ribosomal protein L38 | 0.0173625 |
| PMM2 | phosphomannomutase 2 | 0.0173204 |
| SNED1 | sushi, nidogen and EGF-like domains 1 | 0.0173194 |
| INTS6 | integrator complex subunit 6 | 0.0171572 |
| CDHR3 | cadherin-related family member 3 | 0.0169369 |
| GPATCH8 | G patch domain containing 8 | 0.0168967 |
| EXOC4 | exocyst complex component 4 | 0.0168665 |
| FBXO34 | F-box protein 34 | 0.0167366 |
| AHNAK | AHNAK nucleoprotein | 0.0164984 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | 0.015989 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0159145 |
| CCNH | cyclin H | 0.0158328 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0158101 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.01574 |
| WTAP | Wilms tumor 1 associated protein | 0.0157242 |
| ATG7 | autophagy related 7 | 0.015721 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0157038 |
| S100A2 | S100 calcium binding protein A2 | 0.0156367 |
| XPO7 | exportin 7 | 0.015591 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0155452 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0155057 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0155049 |
| AATF | apoptosis antagonizing transcription factor | 0.0153417 |
| KLK6 | kallikrein-related peptidase 6 | 0.0152385 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0151424 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0150496 |
| CFAP161 | cilia and flagella associated protein 161 | 0.0149951 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0147402 |
| SAFB | scaffold attachment factor B | 0.0146472 |
| RPS24 | ribosomal protein S24 | 0.0145527 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0143875 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0143682 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.014281 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | -0.204697 |
| AREG | amphiregulin | -0.149073 |
| PTMA | prothymosin, alpha | -0.13599 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.128215 |
| EGR1 | early growth response 1 | -0.113879 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.110657 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.101439 |
| RPS6 | ribosomal protein S6 | -0.0931305 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0919166 |
| TMSB10 | thymosin beta 10 | -0.089366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0891062 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0875398 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0847696 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0829556 |
| EZR | ezrin | -0.076058 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0758964 |
| ANXA1 | annexin A1 | -0.075789 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0745509 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0711605 |
| NDRG1 | N-myc downstream regulated 1 | -0.0708574 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.06692 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.066462 |
| OXR1 | oxidation resistance 1 | -0.0663613 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0637555 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0619043 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0587286 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0582017 |
| FOSL1 | FOS-like antigen 1 | -0.0559406 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0558031 |
| TXNIP | thioredoxin interacting protein | -0.0555185 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.052629 |
| GOLGA4 | golgin A4 | -0.0524433 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0522891 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0514256 |
| COG5 | component of oligomeric golgi complex 5 | -0.0507688 |
| ANXA2 | annexin A2 | -0.0506457 |
| RUNX2 | runt-related transcription factor 2 | -0.0503462 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0502034 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0499353 |
| CLTC | clathrin, heavy chain (Hc) | -0.0498936 |
| RREB1 | ras responsive element binding protein 1 | -0.0495173 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0493413 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0493264 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0492257 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0480095 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0473458 |
| PCBP2 | poly(rC) binding protein 2 | -0.0454808 |
| FAM3C | family with sequence similarity 3, member C | -0.0452555 |
| TXNRD1 | thioredoxin reductase 1 | -0.0452441 |
| HMGA1 | high mobility group AT-hook 1 | -0.0452287 |
| IGF2 | insulin-like growth factor 2 | -0.0448587 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0441667 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0434545 |
| CD9 | CD9 molecule | -0.0433596 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0426225 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0424341 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0422827 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0421362 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0420208 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0414768 |
| ZNF292 | zinc finger protein 292 | -0.0414291 |
| NUP58 | nucleoporin 58 | -0.0413307 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0412831 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.04105 |
| CENPF | centromere protein F, 350/400kDa | -0.0410012 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.040942 |
| MED13L | mediator complex subunit 13-like | -0.0406059 |
| RBM25 | RNA binding motif protein 25 | -0.0405479 |
| SLMAP | sarcolemma associated protein | -0.0398206 |
| FMNL2 | formin-like 2 | -0.0397967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0389772 |
| LDHA | lactate dehydrogenase A | -0.0379607 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0376979 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0373702 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0373562 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372275 |
| CBX3 | chromobox homolog 3 | -0.0358076 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0353286 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0349126 |
| EMP1 | epithelial membrane protein 1 | -0.0343395 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0340924 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0339314 |
| PERP | PERP, TP53 apoptosis effector | -0.0337593 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0335468 |
| VMP1 | vacuole membrane protein 1 | -0.0335104 |
| ZFP36 | ZFP36 ring finger protein | -0.0333505 |
| USP3 | ubiquitin specific peptidase 3 | -0.0332403 |
| SBF2 | SET binding factor 2 | -0.0331429 |
| RAB6A | RAB6A, member RAS oncogene family | -0.03311 |
| TOP1 | topoisomerase (DNA) I | -0.0325236 |
| RPS2 | ribosomal protein S2 | -0.0325152 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0322139 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0320242 |
| KIAA0040 | KIAA0040 | -0.0314671 |
| RNF145 | ring finger protein 145 | -0.0313341 |
| KLK10 | kallikrein-related peptidase 10 | -0.0313157 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0311915 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0309632 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0306979 |
| FAM120A | family with sequence similarity 120A | -0.0306784 |