| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0639505 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0629449 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0585193 |
| OGA | O-GlcNAcase | 0.0492006 |
| PLEC | plectin | 0.0483154 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0469715 |
| EZR | ezrin | 0.0451513 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0429563 |
| MORF4L2 | mortality factor 4 like 2 | 0.0409006 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0404305 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0404238 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0402143 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0401965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0368837 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0360005 |
| GOLGA4 | golgin A4 | 0.035211 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0348571 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0340622 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0332138 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0318491 |
| CALU | calumenin | 0.0312484 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.031222 |
| ABHD2 | abhydrolase domain containing 2 | 0.0310778 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0307385 |
| HELZ | helicase with zinc finger | 0.0303148 |
| RBM39 | RNA binding motif protein 39 | 0.0294732 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0294677 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0293391 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0288079 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0285964 |
| SETD5 | SET domain containing 5 | 0.0284054 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0281783 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0279798 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0276792 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0274148 |
| PGK1 | phosphoglycerate kinase 1 | 0.0267951 |
| COPA | coatomer protein complex, subunit alpha | 0.026702 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0266061 |
| ZNF292 | zinc finger protein 292 | 0.0265985 |
| PCM1 | pericentriolar material 1 | 0.0259035 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0257032 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0256075 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0252992 |
| NUP58 | nucleoporin 58 | 0.0251591 |
| EFNB2 | ephrin-B2 | 0.0251551 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0249878 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0249477 |
| TMF1 | TATA element modulatory factor 1 | 0.0249008 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.024676 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.024517 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0244723 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0243696 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0242423 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0241106 |
| SMAD3 | SMAD family member 3 | 0.0241061 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.023893 |
| DSCAM | Down syndrome cell adhesion molecule | 0.023891 |
| HDLBP | high density lipoprotein binding protein | 0.0236292 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0234738 |
| LMO7 | LIM domain 7 | 0.0232361 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.023191 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0230945 |
| SVIL | supervillin | 0.0230399 |
| DIAPH3 | diaphanous-related formin 3 | 0.0229035 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0224803 |
| JMJD1C | jumonji domain containing 1C | 0.0223676 |
| XPO1 | exportin 1 | 0.0221632 |
| RLF | rearranged L-myc fusion | 0.0220672 |
| ETNK1 | ethanolamine kinase 1 | 0.0220169 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0218505 |
| ANLN | anillin, actin binding protein | 0.021713 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0217066 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0215629 |
| RIOK3 | RIO kinase 3 | 0.0215032 |
| SUCO | SUN domain containing ossification factor | 0.0212529 |
| RBM33 | RNA binding motif protein 33 | 0.0211777 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0211691 |
| PDE8A | phosphodiesterase 8A | 0.02086 |
| AFDN | afadin, adherens junction formation factor | 0.0205515 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0204621 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0203445 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0202549 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.019924 |
| ARF4 | ADP-ribosylation factor 4 | 0.0199175 |
| SRP54 | signal recognition particle 54kDa | 0.0197819 |
| COG5 | component of oligomeric golgi complex 5 | 0.0197666 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0195855 |
| RNF43 | ring finger protein 43 | 0.0195062 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0194519 |
| WDR45B | WD repeat domain 45B | 0.0193974 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0193851 |
| NDRG1 | N-myc downstream regulated 1 | 0.0191624 |
| USP3 | ubiquitin specific peptidase 3 | 0.0191389 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0191339 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0190245 |
| WDR26 | WD repeat domain 26 | 0.0190176 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0189905 |
| SEC24A | SEC24 family member A | 0.0188797 |
| TXNIP | thioredoxin interacting protein | 0.0186411 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0186324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.285914 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.150364 |
| PTMA | prothymosin, alpha | -0.140861 |
| CDH13 | cadherin 13 | -0.105136 |
| NAV2 | neuron navigator 2 | -0.102504 |
| CCND1 | cyclin D1 | -0.100143 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0987744 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0922486 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0838807 |
| TMSB10 | thymosin beta 10 | -0.0834999 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0834158 |
| VCL | vinculin | -0.0772687 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0761177 |
| RPL35A | ribosomal protein L35a | -0.075384 |
| CDK6 | cyclin-dependent kinase 6 | -0.0700404 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0694746 |
| RPS6 | ribosomal protein S6 | -0.068455 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0674037 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0653149 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.064696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0636842 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0632938 |
| RAD51B | RAD51 paralog B | -0.06134 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0607461 |
| RPS12 | ribosomal protein S12 | -0.0578377 |
| RPL26 | ribosomal protein L26 | -0.0553815 |
| RPL37A | ribosomal protein L37a | -0.0524105 |
| RPS3 | ribosomal protein S3 | -0.0474134 |
| RPS19 | ribosomal protein S19 | -0.0472399 |
| HMGA1 | high mobility group AT-hook 1 | -0.0460703 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0459514 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0452593 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0448927 |
| EXOC4 | exocyst complex component 4 | -0.0448531 |
| RPL9 | ribosomal protein L9 | -0.0448478 |
| WWOX | WW domain containing oxidoreductase | -0.0411308 |
| ASPH | aspartate beta-hydroxylase | -0.0397515 |
| RPS8 | ribosomal protein S8 | -0.0396848 |
| RPL31 | ribosomal protein L31 | -0.0396553 |
| RPL37 | ribosomal protein L37 | -0.0395268 |
| ITGB4 | integrin, beta 4 | -0.0394358 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0384458 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0373882 |
| RPL23 | ribosomal protein L23 | -0.0370581 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0366239 |
| KRT18 | keratin 18, type I | -0.0364012 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0361554 |
| INTS6 | integrator complex subunit 6 | -0.0360865 |
| RPS13 | ribosomal protein S13 | -0.036081 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0358268 |
| FHIT | fragile histidine triad | -0.0347119 |
| FLNB | filamin B, beta | -0.034446 |
| RBP1 | retinol binding protein 1, cellular | -0.0343122 |
| ACTG1 | actin gamma 1 | -0.0342301 |
| SYT1 | synaptotagmin I | -0.0342287 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.034075 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0339552 |
| RPS17 | ribosomal protein S17 | -0.0337275 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0334349 |
| FRMD5 | FERM domain containing 5 | -0.0333398 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0330569 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330321 |
| RPS27A | ribosomal protein S27a | -0.0328844 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.03263 |
| MT2A | metallothionein 2A | -0.0325418 |
| FTL | ferritin, light polypeptide | -0.0324584 |
| SET | SET nuclear proto-oncogene | -0.0319878 |
| POTEF | POTE ankyrin domain family, member F | -0.0315115 |
| PCDH9 | protocadherin 9 | -0.0312313 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0311631 |
| LDHA | lactate dehydrogenase A | -0.0309705 |
| BCL2L1 | BCL2-like 1 | -0.0299217 |
| ANXA3 | annexin A3 | -0.0298464 |
| RPLP2 | ribosomal protein, large, P2 | -0.0296418 |
| RPS24 | ribosomal protein S24 | -0.0296031 |
| CBX3 | chromobox homolog 3 | -0.0295017 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0294381 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0292974 |
| VIM | vimentin | -0.0289968 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0289748 |
| TUBB4B | tubulin, beta 4B class IVb | -0.028935 |
| CBX5 | chromobox homolog 5 | -0.0288705 |
| UBAP2 | ubiquitin associated protein 2 | -0.02879 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0285126 |
| PHF14 | PHD finger protein 14 | -0.0281783 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0280023 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0279904 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0278968 |
| PFN1 | profilin 1 | -0.0273109 |
| IGF2 | insulin-like growth factor 2 | -0.0272821 |
| RPS14 | ribosomal protein S14 | -0.0272574 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0272032 |
| ENO1 | enolase 1, (alpha) | -0.0270604 |
| MYOF | myoferlin | -0.0268313 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0265817 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0262891 |
| HMGB1 | high mobility group box 1 | -0.0261876 |
| AIG1 | androgen-induced 1 | -0.0259487 |
| CUX1 | cut-like homeobox 1 | -0.0258638 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0257776 |