| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | S-Adenosyl-L-methionine (disulfate tosylate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the S-Adenosyl-L-methionine (disulfate tosylate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.393645 |
| COL6A3 | collagen, type VI, alpha 3 | 0.157169 |
| COL1A1 | collagen, type I, alpha 1 | 0.155704 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.091671 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0854592 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0804694 |
| HMGA2 | high mobility group AT-hook 2 | 0.0735845 |
| COL1A2 | collagen, type I, alpha 2 | 0.0687486 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0661082 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.064994 |
| FBN1 | fibrillin 1 | 0.0570052 |
| NAV2 | neuron navigator 2 | 0.0545293 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.051016 |
| AHNAK | AHNAK nucleoprotein | 0.0488027 |
| ASPH | aspartate beta-hydroxylase | 0.0486685 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0457047 |
| DST | dystonin | 0.0435238 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0413055 |
| SEPTIN9 | septin 9 | 0.0407023 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0406165 |
| PLEC | plectin | 0.0394677 |
| MYO10 | myosin X | 0.0389533 |
| NAV1 | neuron navigator 1 | 0.0389406 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383581 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0382513 |
| LOX | lysyl oxidase | 0.0380121 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0374859 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0366493 |
| RUNX1 | runt-related transcription factor 1 | 0.0363658 |
| COL3A1 | collagen, type III, alpha 1 | 0.0350831 |
| GLIS3 | GLIS family zinc finger 3 | 0.0348295 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0346016 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0343016 |
| VEGFA | vascular endothelial growth factor A | 0.0341458 |
| SMAD3 | SMAD family member 3 | 0.0341407 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0339262 |
| HDLBP | high density lipoprotein binding protein | 0.0337829 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0335135 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0334737 |
| CALU | calumenin | 0.0327604 |
| COL5A1 | collagen, type V, alpha 1 | 0.0320257 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0311868 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0291118 |
| FLNA | filamin A, alpha | 0.0288795 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0288699 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0287412 |
| COL5A2 | collagen, type V, alpha 2 | 0.0287096 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0285941 |
| ACTG1 | actin gamma 1 | 0.028289 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0281252 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0279034 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0273325 |
| FMNL2 | formin-like 2 | 0.0273154 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0269845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0269168 |
| FUS | FUS RNA binding protein | 0.0266055 |
| INTS6 | integrator complex subunit 6 | 0.0265988 |
| LOXL2 | lysyl oxidase-like 2 | 0.0264421 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0263426 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0256301 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0250803 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0242165 |
| CANX | calnexin | 0.024213 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0238024 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0236212 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.02345 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.023392 |
| MED13L | mediator complex subunit 13-like | 0.0229891 |
| EMP1 | epithelial membrane protein 1 | 0.0228202 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0222165 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0221842 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0215724 |
| DSPP | dentin sialophosphoprotein | 0.0215204 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0213442 |
| SEPTIN11 | septin 11 | 0.0212747 |
| APP | amyloid beta (A4) precursor protein | 0.0212328 |
| CUX1 | cut-like homeobox 1 | 0.0208708 |
| FAT1 | FAT atypical cadherin 1 | 0.020621 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0204897 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0201435 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0196775 |
| MAP4 | microtubule-associated protein 4 | 0.0196308 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0194027 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.019179 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0190418 |
| GOLGA3 | golgin A3 | 0.0188583 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0188443 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0187651 |
| TLN1 | talin 1 | 0.0185822 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0185273 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0184568 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0183448 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0181865 |
| VCAN | versican | 0.018091 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0180889 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0180358 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0179571 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0177905 |
| FRMD6 | FERM domain containing 6 | 0.0177861 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0177785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INHBA | inhibin, beta A | -0.154886 |
| TMSB10 | thymosin beta 10 | -0.100949 |
| VIM | vimentin | -0.0741837 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0728068 |
| MT2A | metallothionein 2A | -0.0623262 |
| B2M | beta-2-microglobulin | -0.0574065 |
| STC1 | stanniocalcin 1 | -0.0558368 |
| HLA-B | major histocompatibility complex, class I, B | -0.0476817 |
| FTL | ferritin, light polypeptide | -0.0473776 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0385754 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0378584 |
| RPS12 | ribosomal protein S12 | -0.0367251 |
| RPS3 | ribosomal protein S3 | -0.0362851 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0360351 |
| EGR1 | early growth response 1 | -0.0357497 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0355875 |
| RPL9 | ribosomal protein L9 | -0.0349597 |
| HLA-A | major histocompatibility complex, class I, A | -0.0317555 |
| RPL23 | ribosomal protein L23 | -0.0311608 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0306558 |
| RPS19 | ribosomal protein S19 | -0.0280754 |
| RPL37A | ribosomal protein L37a | -0.0277977 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0275251 |
| RPS6 | ribosomal protein S6 | -0.0265471 |
| TMEM165 | transmembrane protein 165 | -0.0259341 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0231763 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227025 |
| RACK1 | receptor for activated C kinase 1 | -0.0221611 |
| RPL34 | ribosomal protein L34 | -0.0221327 |
| RPL36 | ribosomal protein L36 | -0.0216025 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0215341 |
| RPL11 | ribosomal protein L11 | -0.0214479 |
| PRSS23 | protease, serine, 23 | -0.0213852 |
| PFN1 | profilin 1 | -0.020898 |
| POMP | proteasome maturation protein | -0.0204707 |
| NDRG1 | N-myc downstream regulated 1 | -0.0190339 |
| PDE8A | phosphodiesterase 8A | -0.018906 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0187913 |
| RPL30 | ribosomal protein L30 | -0.0186446 |
| RPS14 | ribosomal protein S14 | -0.0185536 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0185438 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.018345 |
| S100A6 | S100 calcium binding protein A6 | -0.0182108 |
| RPL37 | ribosomal protein L37 | -0.0181388 |
| RPL19 | ribosomal protein L19 | -0.0180418 |
| RPLP0 | ribosomal protein, large, P0 | -0.0180307 |
| RPL26 | ribosomal protein L26 | -0.017947 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0174277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0172017 |
| PTMA | prothymosin, alpha | -0.0171658 |
| TBX2 | T-box 2 | -0.0168785 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0167846 |
| S100A9 | S100 calcium binding protein A9 | -0.0166845 |
| LOC112694756 | uncharaterized LOC112694756 | -0.016591 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0165004 |
| KLF6 | Kruppel-like factor 6 | -0.0164053 |
| RPL7 | ribosomal protein L7 | -0.0158153 |
| RPS8 | ribosomal protein S8 | -0.0155828 |
| RPL5 | ribosomal protein L5 | -0.015386 |
| TOP1 | topoisomerase (DNA) I | -0.0153171 |
| OXR1 | oxidation resistance 1 | -0.0153145 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.015237 |
| RPL12 | ribosomal protein L12 | -0.0152336 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0152123 |
| RPS4X | ribosomal protein S4, X-linked | -0.015129 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0151121 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0149223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0146237 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0145755 |
| RPS17 | ribosomal protein S17 | -0.0145297 |
| TMEM263 | transmembrane protein 263 | -0.0144175 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.014306 |
| RPL31 | ribosomal protein L31 | -0.0142206 |
| RAB13 | RAB13, member RAS oncogene family | -0.0142179 |
| MAP1B | microtubule-associated protein 1B | -0.0140647 |
| H3-3B | H3.3 histone B | -0.0138081 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0137658 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0136799 |
| RNF24 | ring finger protein 24 | -0.0133784 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0133414 |
| TMEM87A | transmembrane protein 87A | -0.0131531 |
| SET | SET nuclear proto-oncogene | -0.0131529 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0130571 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0129941 |
| MMP1 | matrix metallopeptidase 1 | -0.0128603 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0128181 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0126111 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0125223 |
| TPI1 | triosephosphate isomerase 1 | -0.012521 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.012239 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0122012 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0121489 |
| SERF2 | small EDRK-rich factor 2 | -0.0121085 |
| TAGLN2 | transgelin 2 | -0.0117043 |
| RPL35A | ribosomal protein L35a | -0.0116572 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0116504 |
| RPLP2 | ribosomal protein, large, P2 | -0.0116462 |
| RPL35 | ribosomal protein L35 | -0.0116224 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0115615 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0115097 |
