S-propranolol-2961 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the S-propranolol-2961 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANKRD26 ankyrin repeat domain 26
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
AQP1 aquaporin 1 (Colton blood group)
AURKA aurora kinase A
BCR breakpoint cluster region
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CCL4 chemokine (C-C motif) ligand 4
CCSER2 coiled-coil serine-rich protein 2
CDR2L cerebellar degeneration-related protein 2-like
CECR1 cat eye syndrome chromosome region, candidate 1
CGREF1 cell growth regulator with EF-hand domain 1
CHD9 chromodomain helicase DNA binding protein 9
CREM cAMP responsive element modulator
CSNK1E casein kinase 1, epsilon
CXCR3 chemokine (C-X-C motif) receptor 3
DENND5B DENN/MADD domain containing 5B
DFNB31 deafness, autosomal recessive 31
EML3 echinoderm microtubule associated protein like 3
ENG endoglin
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM3A family with sequence similarity 3, member A
FGL1 fibrinogen-like 1
FHL3 four and a half LIM domains 3
FOXG1 forkhead box G1
FRS3 fibroblast growth factor receptor substrate 3
GCFC2 GC-rich sequence DNA-binding factor 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GHRHR growth hormone releasing hormone receptor
GMPR guanosine monophosphate reductase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR21 G protein-coupled receptor 21
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAMP hepcidin antimicrobial peptide
HDLBP high density lipoprotein binding protein
HOXA5 homeobox A5
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL6ST interleukin 6 signal transducer
INO80B INO80 complex subunit B
IZUMO4 IZUMO family member 4
LPAR1 lysophosphatidic acid receptor 1
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAGED2 melanoma antigen family D2
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7CL MAP3K7 C-terminal like
MID1 midline 1
MIR22HG MIR22 host gene
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYRF myelin regulatory factor
NCAPH2 non-SMC condensin II complex, subunit H2
NLRP1 NLR family, pyrin domain containing 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NR6A1 nuclear receptor subfamily 6, group A, member 1
PCGF2 polycomb group ring finger 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM7 PDZ and LIM domain 7 (enigma)
PEG10 paternally expressed 10
PEX10 peroxisomal biogenesis factor 10
PEX3 peroxisomal biogenesis factor 3
PHF3 PHD finger protein 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEC plectin
PLXNA1 plexin A1
PNPLA4 patatin-like phospholipase domain containing 4
PRPF18 pre-mRNA processing factor 18
PRPH2 peripherin 2 (retinal degeneration, slow)
PTCRA pre T-cell antigen receptor alpha
PYGB phosphorylase, glycogen; brain
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS10 regulator of G-protein signaling 10
RGS12 regulator of G-protein signaling 12
RGS5 regulator of G-protein signaling 5
RPL13P5 ribosomal protein L13 pseudogene 5
RXRB retinoid X receptor, beta
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFN stratifin
SIRPB1 signal-regulatory protein beta 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPN sialophorin
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TRADD TNFRSF1A-associated via death domain
XAB2 XPA binding protein 2
ZBTB20 zinc finger and BTB domain containing 20
ZNF276 zinc finger protein 276
ZNF337 zinc finger protein 337
ZNF428 zinc finger protein 428
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADAM23 ADAM metallopeptidase domain 23
AHDC1 AT hook, DNA binding motif, containing 1
ALS2CL ALS2 C-terminal like
ANO10 anoctamin 10
AOAH acyloxyacyl hydrolase (neutrophil)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARL15 ADP-ribosylation factor-like 15
ARMC7 armadillo repeat containing 7
AVEN apoptosis, caspase activation inhibitor
C14ORF93 chromosome 14 open reading frame 93
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
CD300C CD300c molecule
CD38 CD38 molecule
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLTCL1 clathrin, heavy chain-like 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CTSG cathepsin G
CXORF56 chromosome X open reading frame 56
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDN dendrin
ECSIT ECSIT signalling integrator
F8 coagulation factor VIII, procoagulant component
FAM204A family with sequence similarity 204, member A
FAM50B family with sequence similarity 50, member B
FGGY FGGY carbohydrate kinase domain containing
FKBPL FK506 binding protein like
FZD2 frizzled class receptor 2
GEM GTP binding protein overexpressed in skeletal muscle
GID4 GID complex subunit 4
GIMAP6 GTPase, IMAP family member 6
GLCE glucuronic acid epimerase
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRAMD1B GRAM domain containing 1B
GTF2IRD1 GTF2I repeat domain containing 1
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BO histone cluster 1, H2bo
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF7 interferon regulatory factor 7
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP3 low density lipoprotein receptor-related protein 3
LY6E lymphocyte antigen 6 complex, locus E
MAGED1 melanoma antigen family D1
MCOLN1 mucolipin 1
MICA MHC class I polypeptide-related sequence A
MX1 MX dynamin-like GTPase 1
NBEAL2 neurobeachin-like 2
NFE2L3 nuclear factor, erythroid 2-like 3
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOL6 nucleolar protein 6 (RNA-associated)
PARG poly (ADP-ribose) glycohydrolase
PECR peroxisomal trans-2-enoyl-CoA reductase
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
POMZP3 POM121 and ZP3 fusion
POR P450 (cytochrome) oxidoreductase
PRR14L proline rich 14-like
PTGES2 prostaglandin E synthase 2
RHOH ras homolog family member H
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RUSC2 RUN and SH3 domain containing 2
S100A12 S100 calcium binding protein A12
SARS2 seryl-tRNA synthetase 2, mitochondrial
SHARPIN SHANK-associated RH domain interactor
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPAG7 sperm associated antigen 7
STEAP3 STEAP family member 3, metalloreductase
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAOK1 TAO kinase 1
THEM6 thioesterase superfamily member 6
TMEM134 transmembrane protein 134
TMEM159 transmembrane protein 159
TMEM184C transmembrane protein 184C
TMEM57 transmembrane protein 57
TRAPPC2L trafficking protein particle complex 2-like
TTC27 tetratricopeptide repeat domain 27
TXNL4B thioredoxin-like 4B
UBIAD1 UbiA prenyltransferase domain containing 1
UPP1 uridine phosphorylase 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP36 ubiquitin specific peptidase 36
WDR46 WD repeat domain 46
ZBED1 zinc finger, BED-type containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF250 zinc finger protein 250
ZNF574 zinc finger protein 574
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862