S-propranolol-6343 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the S-propranolol-6343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APOC1 apolipoprotein C-I
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ARHGAP1 Rho GTPase activating protein 1
ARSB arylsulfatase B
ATF6B activating transcription factor 6 beta
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BTN3A2 butyrophilin, subfamily 3, member A2
C1ORF68 chromosome 1 open reading frame 68
CA5BP1 carbonic anhydrase VB pseudogene 1
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCPG1 cell cycle progression 1
CLTB clathrin, light chain B
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL1A1 collagen, type I, alpha 1
DCTN1 dynactin 1
DENND3 DENN/MADD domain containing 3
EFNA3 ephrin-A3
ELMO2 engulfment and cell motility 2
FGF1 fibroblast growth factor 1 (acidic)
FGL1 fibrinogen-like 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEXIM1 hexamethylene bis-acetamide inducible 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA1 homeobox A1
HOXB5 homeobox B5
HOXC10 homeobox C10
HOXC11 homeobox C11
IFT122 intraflagellar transport 122
IGFBP1 insulin-like growth factor binding protein 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL2RB interleukin 2 receptor, beta
ITGB5 integrin, beta 5
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA0509 uncharacterized LOC57242
KLK7 kallikrein-related peptidase 7
KRAS Kirsten rat sarcoma viral oncogene homolog
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIMD2 LIM domain containing 2
LIMK1 LIM domain kinase 1
LMO7 LIM domain 7
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K7 mitogen-activated protein kinase kinase 7
MB myoglobin
MCF2L MCF.2 cell line derived transforming sequence-like
MINK1 misshapen-like kinase 1
MORC1 MORC family CW-type zinc finger 1
MYOF myoferlin
NARFL nuclear prelamin A recognition factor-like
NDE1 nudE neurodevelopment protein 1
NEK11 NIMA-related kinase 11
NPAS2 neuronal PAS domain protein 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAPPA2 pappalysin 2
PASK PAS domain containing serine/threonine kinase
PCDHGA10 protocadherin gamma subfamily A, 10
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PLCH1 phospholipase C, eta 1
PLD2 phospholipase D2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB36 RAB36, member RAS oncogene family
RHOT2 ras homolog family member T2
RNF19B ring finger protein 19B
RPAIN RPA interacting protein
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B1 SH2B adaptor protein 1
SPRED2 sprouty-related, EVH1 domain containing 2
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYK spleen tyrosine kinase
TEF thyrotrophic embryonic factor
THRA thyroid hormone receptor, alpha
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRAPPC6A trafficking protein particle complex 6A
UBE3B ubiquitin protein ligase E3B
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
WDR1 WD repeat domain 1
WDR33 WD repeat domain 33
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF446 zinc finger protein 446
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD11 abhydrolase domain containing 11
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM15 ADAM metallopeptidase domain 15
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BAK1 BCL2-antagonist/killer 1
BBS7 Bardet-Biedl syndrome 7
BCCIP BRCA2 and CDKN1A interacting protein
BEND5 BEN domain containing 5
C11ORF63 chromosome 11 open reading frame 63
C16ORF62 chromosome 16 open reading frame 62
C1R complement component 1, r subcomponent
CCDC25 coiled-coil domain containing 25
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD70 CD70 molecule
CINP cyclin-dependent kinase 2 interacting protein
CLEC2B C-type lectin domain family 2, member B
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COG7 component of oligomeric golgi complex 7
CTC1 CTS telomere maintenance complex component 1
CXORF40B chromosome X open reading frame 40B
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOLK dolichol kinase
ECM1 extracellular matrix protein 1
EDC3 enhancer of mRNA decapping 3
ENO2 enolase 2 (gamma, neuronal)
FAM102A family with sequence similarity 102, member A
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUZ fuzzy planar cell polarity protein
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HDAC9 histone deacetylase 9
HERC2P3 hect domain and RLD 2 pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H3G histone cluster 1, H3g
HOXC5 homeobox C5
JUP junction plakoglobin
KIAA0753 KIAA0753
KIAA0922 KIAA0922
KIAA1549L KIAA1549-like
KPTN kaptin (actin binding protein)
LYPD1 LY6/PLAUR domain containing 1
MAGEH1 melanoma antigen family H1
MBIP MAP3K12 binding inhibitory protein 1
NCAPH non-SMC condensin I complex, subunit H
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
NT5E 5'-nucleotidase, ecto (CD73)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCID2 PCI domain containing 2
PLA2G15 phospholipase A2, group XV
PMEPA1 prostate transmembrane protein, androgen induced 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
RNF146 ring finger protein 146
RNH1 ribonuclease/angiogenin inhibitor 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
SDC3 syndecan 3
SECISBP2 SECIS binding protein 2
SH2D4A SH2 domain containing 4A
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F6 solute carrier family 35, member F6
SLC35G2 solute carrier family 35, member G2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SREBF1 sterol regulatory element binding transcription factor 1
SUGP1 SURP and G patch domain containing 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC31 tetratricopeptide repeat domain 31
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A
YIPF1 Yip1 domain family, member 1
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF528 zinc finger protein 528
ZNF862 zinc finger protein 862