| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | S100 calcium binding protein A1|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6271) |
| External Link | https://ncbi.nlm.nih.gov/gene/6271 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the S100A1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0287503 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0158107 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0139002 |
| CDC20 | cell division cycle 20 | 0.0136178 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0134347 |
| SORD | sorbitol dehydrogenase | 0.0127299 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0124141 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0114908 |
| WDR61 | WD repeat domain 61 | 0.0108462 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0108016 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.0104164 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00996314 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00989985 |
| TFF1 | trefoil factor 1 | 0.00945737 |
| OLFM4 | olfactomedin 4 | 0.00928922 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00922578 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00910135 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00900923 |
| ZNF589 | zinc finger protein 589 | 0.00899465 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00896144 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00892142 |
| NPTX2 | neuronal pentraxin II | 0.00888043 |
| NTS | neurotensin | 0.0086865 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00867199 |
| AOC1 | amine oxidase, copper containing 1 | 0.00863621 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00861773 |
| TSPAN8 | tetraspanin 8 | 0.00861323 |
| KLK11 | kallikrein-related peptidase 11 | 0.00856269 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00854257 |
| C7 | complement component 7 | 0.00817608 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00812882 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00811871 |
| ENOPH1 | enolase-phosphatase 1 | 0.00804698 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00800548 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00791776 |
| SST | somatostatin | 0.00791425 |
| CRYL1 | crystallin, lambda 1 | 0.00766626 |
| RPA2 | replication protein A2, 32kDa | 0.00764324 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00753551 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00753248 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.00737774 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00737099 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00736414 |
| NUP85 | nucleoporin 85kDa | 0.00729768 |
| NMU | neuromedin U | 0.00726701 |
| ANO10 | anoctamin 10 | 0.00726112 |
| HMGB2 | high mobility group box 2 | 0.00725862 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00725436 |
| PLK1 | polo-like kinase 1 | 0.00723925 |
| CHN2 | chimerin 2 | 0.00714186 |
| ADD3 | adducin 3 (gamma) | 0.0071109 |
| NEK2 | NIMA-related kinase 2 | 0.00703187 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00700986 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00700471 |
| ABHD10 | abhydrolase domain containing 10 | 0.00698375 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00695246 |
| H1-10 | H1.10 linker histone | 0.00693513 |
| DCK | deoxycytidine kinase | 0.00692049 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00691098 |
| FLOT2 | flotillin 2 | 0.00688992 |
| COLEC11 | collectin sub-family member 11 | 0.00686683 |
| FTO | fat mass and obesity associated | 0.00686666 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00684883 |
| ARG2 | arginase 2 | 0.00684861 |
| LYZ | lysozyme | 0.00683743 |
| TUBA1A | tubulin, alpha 1a | 0.00683124 |
| ACP3 | acid phosphatase 3 | 0.00677184 |
| COMMD8 | COMM domain containing 8 | 0.00677169 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00676508 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00675073 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00674504 |
| PIMREG | PICALM interacting mitotic regulator | 0.00671933 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00671767 |
| CALML4 | calmodulin-like 4 | 0.0067146 |
| KIF20A | kinesin family member 20A | 0.00669926 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00669901 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.0066919 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00665051 |
| TSPAN7 | tetraspanin 7 | 0.0066341 |
| MARCKSL1 | MARCKS-like 1 | 0.00663351 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00663292 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00660505 |
| EMC9 | ER membrane protein complex subunit 9 | 0.00658712 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0065802 |
| CD320 | CD320 molecule | 0.00657959 |
| EAF2 | ELL associated factor 2 | 0.00653237 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00652958 |
| SLC2A4RG | SLC2A4 regulator | 0.00652367 |
| ARG1 | arginase 1 | 0.00652123 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00651309 |
| TMPO | thymopoietin | 0.00648208 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00648197 |
| GUCY2C | guanylate cyclase 2C | 0.00646787 |
| APIP | APAF1 interacting protein | 0.0064659 |
| KIAA0100 | KIAA0100 | 0.00646582 |
| HOXB6 | homeobox B6 | 0.00641742 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.00637559 |
| H2AFV | H2A histone family, member V | 0.00637183 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00635594 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00635479 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00634667 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00634409 |
| KLK12 | kallikrein-related peptidase 12 | 0.00634185 |
| CCDC85B | coiled-coil domain containing 85B | 0.00631701 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00630295 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00627539 |
| SNCAIP | synuclein, alpha interacting protein | 0.00625235 |
| PTK2 | protein tyrosine kinase 2 | 0.00624989 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00624334 |
| THYN1 | thymocyte nuclear protein 1 | 0.00624104 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00621337 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00620764 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00620294 |
| CCNA2 | cyclin A2 | 0.00619645 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00618524 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00618479 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00618009 |
| PAH | phenylalanine hydroxylase | 0.00616527 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0061595 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00615874 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00615174 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00614289 |
| CDC42 | cell division cycle 42 | 0.00613485 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00613265 |
| ESD | esterase D | 0.00612411 |
| TMEM106C | transmembrane protein 106C | 0.00611382 |
| CTSG | cathepsin G | 0.00610888 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00606837 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00606419 |
| OIP5 | Opa interacting protein 5 | 0.00606031 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00605542 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00605424 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00605152 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00603957 |
| TMEM14A | transmembrane protein 14A | 0.00603742 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00602862 |
| HAL | histidine ammonia-lyase | 0.00602524 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.0060199 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.0060055 |
| GRAMD1C | GRAM domain containing 1C | 0.00599353 |
| TMEM38B | transmembrane protein 38B | 0.00598906 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00597544 |
| CHKB | choline kinase beta | 0.00596497 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00595961 |
| UBE2N | ubiquitin-conjugating enzyme E2N | 0.00593305 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00593042 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00592671 |
| NUP37 | nucleoporin 37kDa | 0.0059255 |
| RPS5 | ribosomal protein S5 | 0.0059032 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.0058971 |
| EIF4E | eukaryotic translation initiation factor 4E | 0.0058815 |
| AGR2 | anterior gradient 2 | 0.00587932 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0058713 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00586146 |
| RANBP1 | RAN binding protein 1 | 0.00581426 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.0057971 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 0.00579409 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00579407 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00578597 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00573968 |
| CCNB2 | cyclin B2 | 0.00573694 |
| AURKA | aurora kinase A | 0.00572269 |
| PRSS3 | protease, serine, 3 | 0.00572252 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00571199 |
| CA14 | carbonic anhydrase XIV | 0.00570849 |
| PLN | phospholamban | 0.00569291 |
| HEPH | hephaestin | 0.00568521 |
| POLB | polymerase (DNA directed), beta | 0.00567715 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00566697 |
| ESR1 | estrogen receptor 1 | 0.00566559 |
| PLP1 | proteolipid protein 1 | 0.00565448 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00564702 |
| RPA3 | replication protein A3, 14kDa | 0.00564633 |
| FASN | fatty acid synthase | 0.0056425 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00564086 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00561386 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00560472 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.00560257 |
| ERLIN2 | ER lipid raft associated 2 | 0.00559765 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00559046 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00558885 |
| NPY | neuropeptide Y | 0.00558036 |
| MANSC1 | MANSC domain containing 1 | 0.00557454 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00557273 |
| LMNB1 | lamin B1 | 0.0055719 |
| CYB561 | cytochrome b561 | 0.00554434 |
| GGCT | gamma-glutamylcyclotransferase | 0.00553465 |
| MT1G | metallothionein 1G | 0.00553258 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00552746 |
| KLHL23 | kelch-like family member 23 | 0.00551577 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00551492 |
| TRMT5 | tRNA methyltransferase 5 | 0.00550149 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00547714 |
| ASRGL1 | asparaginase like 1 | 0.00547331 |
| PDZD8 | PDZ domain containing 8 | 0.00547142 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00546172 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00546095 |
| MAL | mal, T-cell differentiation protein | 0.00545882 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00544852 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00543262 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0054295 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00541768 |
| TCF21 | transcription factor 21 | 0.00541187 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00540878 |
| MICU2 | mitochondrial calcium uptake 2 | 0.00540775 |
| GLRX5 | glutaredoxin 5 | 0.00539778 |
| ZMYM3 | zinc finger, MYM-type 3 | 0.00539372 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00538953 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.00537019 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00536328 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00536153 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00535435 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00535082 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00534702 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | 0.00534128 |
| FAM111A | family with sequence similarity 111, member A | 0.00533509 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00533139 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 0.00532978 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00532851 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00532343 |
| HMGB3 | high mobility group box 3 | 0.00530861 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00530753 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00529385 |
| CHGA | chromogranin A | 0.00528494 |
| KRT1 | keratin 1, type II | 0.00528271 |
| CA12 | carbonic anhydrase XII | 0.00527551 |
| CHPT1 | choline phosphotransferase 1 | 0.00527184 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0052675 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00526436 |
| HAT1 | histone acetyltransferase 1 | 0.00525754 |
| FABP1 | fatty acid binding protein 1, liver | 0.0052566 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00525609 |
| TXNIP | thioredoxin interacting protein | 0.00524138 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.00523832 |
| FST | follistatin | 0.00523638 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00523352 |
| MATN2 | matrilin 2 | 0.00522664 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00522192 |
| ACTL6A | actin-like 6A | 0.00520881 |
| ANXA6 | annexin A6 | 0.00520751 |
| DDHD2 | DDHD domain containing 2 | 0.00519804 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00519729 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00519334 |
| RAB25 | RAB25, member RAS oncogene family | 0.00518197 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00517131 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00516598 |
| CDCA4 | cell division cycle associated 4 | 0.00516405 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00515661 |
| PLVAP | plasmalemma vesicle associated protein | 0.00515657 |
| CANT1 | calcium activated nucleotidase 1 | 0.00515209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0242728 |
| KRT7 | keratin 7, type II | -0.02062 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0193427 |
| SIK1 | salt-inducible kinase 1 | -0.0126009 |
| KRT17 | keratin 17, type I | -0.0124432 |
| KRT14 | keratin 14, type I | -0.0123042 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0122105 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0121127 |
| CADM1 | cell adhesion molecule 1 | -0.0119939 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0116167 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0113537 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0110447 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0110338 |
| OXTR | oxytocin receptor | -0.0108782 |
| DSP | desmoplakin | -0.0106786 |
| KRT15 | keratin 15, type I | -0.0104436 |
| CRYAB | crystallin, alpha B | -0.0104188 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0103276 |
| PIP | prolactin-induced protein | -0.0102868 |
| C3 | complement component 3 | -0.0102307 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00998994 |
| FOLR1 | folate receptor 1 (adult) | -0.00982977 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00972039 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00963875 |
| GOLGA8A | golgin A8 family, member A | -0.00959691 |
| POSTN | periostin, osteoblast specific factor | -0.00943441 |
| TRIB3 | tribbles pseudokinase 3 | -0.00936915 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00920888 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00903027 |
| SNAI2 | snail family zinc finger 2 | -0.0090204 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00897561 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00895557 |
| RBM34 | RNA binding motif protein 34 | -0.00890144 |
| LAMB3 | laminin, beta 3 | -0.0088956 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00872975 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00866819 |
| TCTA | T-cell leukemia translocation altered | -0.00861863 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00860155 |
| AREG | amphiregulin | -0.00859088 |
| HMOX1 | heme oxygenase 1 | -0.00857734 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00856634 |
| CFB | complement factor B | -0.00845004 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00840788 |
| INHBA | inhibin, beta A | -0.00837519 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00830051 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00821139 |
| EMP1 | epithelial membrane protein 1 | -0.00817494 |
| SIRPA | signal-regulatory protein alpha | -0.0081731 |
| GNAS | GNAS complex locus | -0.00817301 |
| LAMC2 | laminin, gamma 2 | -0.00811851 |
| VGLL4 | vestigial-like family member 4 | -0.00804823 |
| PTHLH | parathyroid hormone-like hormone | -0.00803063 |
| PXDC1 | PX domain containing 1 | -0.00800539 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00792397 |
| S100A10 | S100 calcium binding protein A10 | -0.0078939 |
| DIPK1A | divergent protein kinase domain 1A | -0.00787573 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00787051 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00784313 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00783916 |
| IER5 | immediate early response 5 | -0.00782499 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00779808 |
| CHI3L2 | chitinase 3-like 2 | -0.00774998 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00771581 |
| PDE4DIP | phosphodiesterase 4D interacting protein | -0.00766949 |
| ASS1 | argininosuccinate synthase 1 | -0.00766716 |
| MVP | major vault protein | -0.00764539 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00759734 |
| KRT23 | keratin 23, type I | -0.00754557 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00754472 |
| CD14 | CD14 molecule | -0.00754424 |
| MCL1 | myeloid cell leukemia 1 | -0.00750674 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0074154 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00740749 |
| OSMR | oncostatin M receptor | -0.00739848 |
| IL6R | interleukin 6 receptor | -0.00737055 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00736855 |
| EGR1 | early growth response 1 | -0.00736465 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0073486 |
| ADM | adrenomedullin | -0.00730697 |
| DUSP5 | dual specificity phosphatase 5 | -0.00724406 |
| SYNM | synemin, intermediate filament protein | -0.00721742 |
| RHOB | ras homolog family member B | -0.00721076 |
| RGS16 | regulator of G-protein signaling 16 | -0.0072095 |
| PTGES | prostaglandin E synthase | -0.00718248 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00716163 |
| MX1 | MX dynamin-like GTPase 1 | -0.00714107 |
| DDRGK1 | DDRGK domain containing 1 | -0.00713293 |
| RUNX1 | runt-related transcription factor 1 | -0.00712884 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00706504 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00706277 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00703851 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00703092 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00695888 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00695656 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00694485 |
| CP | ceruloplasmin (ferroxidase) | -0.00694317 |
| SMAD7 | SMAD family member 7 | -0.00694169 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00693589 |
| VEGFA | vascular endothelial growth factor A | -0.00691614 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.0068936 |
| DUSP2 | dual specificity phosphatase 2 | -0.006884 |
| TRIM29 | tripartite motif containing 29 | -0.00686562 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00683192 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00679454 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00671691 |
| GPR137B | G protein-coupled receptor 137B | -0.00671508 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00670849 |
| USP47 | ubiquitin specific peptidase 47 | -0.00669516 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00667853 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00664518 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00664454 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00660926 |
| MMP7 | matrix metallopeptidase 7 | -0.00656718 |
| ENAH | enabled homolog (Drosophila) | -0.00653212 |
| ATF3 | activating transcription factor 3 | -0.00653151 |
| RRAGD | Ras-related GTP binding D | -0.00651505 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00650181 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0064813 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00646966 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0064662 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00644186 |
| GSDME | gasdermin E | -0.0064353 |
| KLHL24 | kelch-like family member 24 | -0.00641504 |
| EGR2 | early growth response 2 | -0.00640959 |
| LRRC15 | leucine rich repeat containing 15 | -0.0064041 |
| CD163 | CD163 molecule | -0.00640258 |
| ZNF281 | zinc finger protein 281 | -0.00639603 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00637937 |
| STC2 | stanniocalcin 2 | -0.00636085 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00636032 |
| CEL | carboxyl ester lipase | -0.00636005 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00635796 |
| PDZD2 | PDZ domain containing 2 | -0.00634766 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00634284 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00633698 |
| CALML5 | calmodulin-like 5 | -0.00633495 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.00631791 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00631637 |
| IL32 | interleukin 32 | -0.00631587 |
| HOXC10 | homeobox C10 | -0.00630338 |
| THBS2 | thrombospondin 2 | -0.00629747 |
| MFAP5 | microfibrillar associated protein 5 | -0.00628729 |
| MEF2C | myocyte enhancer factor 2C | -0.00627644 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00626895 |
| ZNF160 | zinc finger protein 160 | -0.00626257 |
| UPK1B | uroplakin 1B | -0.00626234 |
| IRS2 | insulin receptor substrate 2 | -0.00626113 |
| NNMT | nicotinamide N-methyltransferase | -0.00623869 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00623291 |
| BTG3 | BTG family, member 3 | -0.00622436 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0062229 |
| KIAA0040 | KIAA0040 | -0.00621231 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00620187 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00619437 |
| C4BPA | complement component 4 binding protein, alpha | -0.00619211 |
| KRT5 | keratin 5, type II | -0.00616863 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.00616749 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00616721 |
| RPS27L | ribosomal protein S27-like | -0.00615657 |
| DUSP3 | dual specificity phosphatase 3 | -0.00612498 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00612218 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00609004 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00607644 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00606833 |
| KLF9 | Kruppel-like factor 9 | -0.00605425 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00603886 |
| NCOA3 | nuclear receptor coactivator 3 | -0.00603803 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00603181 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00603036 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.00602592 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00602481 |
| TLR2 | toll-like receptor 2 | -0.00599382 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00597592 |
| CLU | clusterin | -0.00596772 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00592613 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00591313 |
| ANOS1 | anosmin 1 | -0.0059114 |
| NOTCH2NL | notch 2 N-terminal like | -0.00591061 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00590995 |
| STX4 | syntaxin 4 | -0.0059059 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00590367 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00589711 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00588186 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00587872 |
| RNFT1 | ring finger protein, transmembrane 1 | -0.00587354 |
| ZFP36 | ZFP36 ring finger protein | -0.00586611 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0058563 |
| CTSA | cathepsin A | -0.00584941 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00584317 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00583962 |
| RBPMS | RNA binding protein with multiple splicing | -0.00583938 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00583014 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.0058282 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00582763 |
| ZIC1 | Zic family member 1 | -0.00582629 |
| CSTB | cystatin B (stefin B) | -0.00579388 |
| KLF6 | Kruppel-like factor 6 | -0.00579357 |
| AIM2 | absent in melanoma 2 | -0.00579248 |
| FADS3 | fatty acid desaturase 3 | -0.00579062 |
| FAM107A | family with sequence similarity 107, member A | -0.00578869 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00577343 |
| FAT1 | FAT atypical cadherin 1 | -0.00576743 |
| EZR | ezrin | -0.00576244 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00575551 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00574961 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00573956 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00573904 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00573674 |
| RDX | radixin | -0.00573057 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00573008 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00569171 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00568934 |
| KRT18 | keratin 18, type I | -0.00567601 |
| MGLL | monoglyceride lipase | -0.00567176 |
| RND3 | Rho family GTPase 3 | -0.00566044 |
| WWC1 | WW and C2 domain containing 1 | -0.00565851 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.0056467 |
| PON3 | paraoxonase 3 | -0.00563649 |
| PLK3 | polo-like kinase 3 | -0.00562002 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00561641 |
| EDNRB | endothelin receptor type B | -0.00561015 |
| JMJD1C | jumonji domain containing 1C | -0.00559384 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.00557418 |
| GRN | granulin | -0.0055685 |
| HOMER1 | homer scaffolding protein 1 | -0.00556177 |
| BMP2 | bone morphogenetic protein 2 | -0.00555885 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00554838 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00554171 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00553856 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00550907 |
| ZNF721 | zinc finger protein 721 | -0.00550359 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00549997 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00549899 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00549184 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.0054757 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00546118 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00546107 |
| GRAMD2B | GRAM domain containing 2B | -0.00545671 |
| TPP1 | tripeptidyl peptidase I | -0.00545347 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00545314 |
| HDAC9 | histone deacetylase 9 | -0.00544675 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00543065 |
| PDE8B | phosphodiesterase 8B | -0.00541444 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.00541336 |
| CUX1 | cut-like homeobox 1 | -0.00539934 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00539834 |
| MMP19 | matrix metallopeptidase 19 | -0.00538596 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0053842 |
| KLF2 | Kruppel-like factor 2 | -0.0053815 |
| RNF114 | ring finger protein 114 | -0.00538021 |
