S100A10 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description S100 calcium binding protein A10|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6281)
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Genes

317 genes differentially expressed following the S100A10 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OR5H6 olfactory receptor, family 5, subfamily H, member 6 (gene/pseudogene) 3.37387
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 3.37387
NPPC natriuretic peptide C 3.37387
EPAS1 endothelial PAS domain protein 1 3.37387
EGFL6 EGF-like-domain, multiple 6 3.37387
SPINK4 serine peptidase inhibitor, Kazal type 4 3.37387
SPINK6 serine peptidase inhibitor, Kazal type 6 3.37387
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.37387
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.37387
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 3.37387
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 3.37387
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 3.37387
FAM153A family with sequence similarity 153, member A 3.37387
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 3.37387
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 3.37387
TAS2R3 taste receptor, type 2, member 3 3.37387
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.37387
SIX3 SIX homeobox 3 3.37387
RNF17 ring finger protein 17 3.37387
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 3.37387
MILR1 mast cell immunoglobulin-like receptor 1 3.37387
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.37387
SIRPB2 signal-regulatory protein beta 2 3.37387
EDDM3A epididymal protein 3A 3.37387
ZNF324B zinc finger protein 324B 3.37387
SOWAHB sosondowah ankyrin repeat domain family member B 3.37387
S100A2 S100 calcium binding protein A2 3.37387
GNRHR gonadotropin-releasing hormone receptor 3.37387
OR51T1 olfactory receptor, family 51, subfamily T, member 1 3.37387
MPL MPL proto-oncogene, thrombopoietin receptor 3.37387
SLC39A12 solute carrier family 39 (zinc transporter), member 12 3.37387
BIRC3 baculoviral IAP repeat containing 3 3.37387
TAL2 T-cell acute lymphocytic leukemia 2 3.37387
MFAP5 microfibrillar associated protein 5 3.37387
SH2D7 SH2 domain containing 7 3.37387
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 3.37387
PLCH2 phospholipase C, eta 2 3.37387
ASB12 ankyrin repeat and SOCS box containing 12 3.37387
NFAM1 NFAT activating protein with ITAM motif 1 3.37387
SSTR5 somatostatin receptor 5 3.37387
SFXN3 sideroflexin 3 3.37387
GYPB glycophorin B (MNS blood group) 3.37387
ACY3 aminoacylase 3 3.37387
PRB4 proline-rich protein BstNI subfamily 4 3.37387
STRIT1 small transmembrane regulator of ion transport 1 3.37387
RAG2 recombination activating gene 2 3.37387
YIPF7 Yip1 domain family, member 7 3.37387
TAS2R60 taste receptor, type 2, member 60 3.37387
STX11 syntaxin 11 3.37387
PKD2L1 polycystic kidney disease 2-like 1 3.37387
PDF peptide deformylase (mitochondrial) 3.37387
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 3.37387
TMPRSS6 transmembrane protease, serine 6 3.37387
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.37387
PHF24 PHD finger protein 24 3.37387
CFAP65 cilia and flagella associated protein 65 3.37387
FAM240A family with sequence similarity 240 member A 3.37387
CPNE8-AS1 CPNE8 antisense RNA 1 3.37387
LOC124902436 talanin 3.37387
GSG1L2 GSG1 like 2 3.37387
TEX46 testis expressed 46 3.37387
SPEM2 SPEM family member 2 3.37387
DUSP29 dual specificity phosphatase 29 3.37387
OPRPN opiorphin prepropeptide 3.37387
IMPG2 interphotoreceptor matrix proteoglycan 2 3.37387
SMTNL1 smoothelin-like 1 3.37387
MAGIX MAGI family member, X-linked 3.37387
CXCL16 chemokine (C-X-C motif) ligand 16 3.37387
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.37387
LOC124903317 uncharacterized LOC124903317 3.37387
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 3.37387
HPR haptoglobin-related protein 3.37387
NXPE1 neurexophilin and PC-esterase domain family, member 1 3.37387
ITK IL2-inducible T-cell kinase 3.37387
TRIM60 tripartite motif containing 60 3.37387
ZIC4 Zic family member 4 3.37387
OVOL3 ovo-like zinc finger 3 3.37387
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.37387
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 3.37387
F5 coagulation factor V (proaccelerin, labile factor) 3.37387
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.37387
LRRN4CL LRRN4 C-terminal like 3.37387
LTF lactotransferrin 3.37387
FAM131C family with sequence similarity 131, member C 3.37387
C6 complement component 6 3.37387
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.37387
PTGDR2 prostaglandin D2 receptor 2 3.37387
GPR12 G protein-coupled receptor 12 3.37387
TCF21 transcription factor 21 3.37387
IL19 interleukin 19 3.37387
IL12A interleukin 12A 3.37387
ECM1 extracellular matrix protein 1 3.37387
DHH desert hedgehog 3.37387
RGCC regulator of cell cycle 3.37387
CSF3R colony stimulating factor 3 receptor (granulocyte) 3.37387
PRR15L proline rich 15-like 3.37387
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.37387
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 3.37387
GH1 growth hormone 1 3.37387
COL6A5 collagen, type VI, alpha 5 3.37387
FGF16 fibroblast growth factor 16 3.37387
WFDC10A WAP four-disulfide core domain 10A 3.37387
ANKRD62 ankyrin repeat domain 62 3.37387
TAT tyrosine aminotransferase 3.37387
EDN2 endothelin 2 3.37387
RESP18 regulated endocrine-specific protein 18 3.37387
FNDC8 fibronectin type III domain containing 8 3.37387
GCOM1 GRINL1A complex locus 1 3.37387
SMIM23 small integral membrane protein 23 3.37387
DGCR6 DiGeorge syndrome critical region gene 6 3.37387
FAM163A family with sequence similarity 163, member A 3.37387
HGFAC HGF activator 3.37387
PLA2G4D phospholipase A2, group IVD (cytosolic) 3.37387
WFDC5 WAP four-disulfide core domain 5 3.37387
RORC RAR-related orphan receptor C 3.37387
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.37387
PCDHGA4 protocadherin gamma subfamily A, 4 3.37387
FCN1 ficolin (collagen/fibrinogen domain containing) 1 3.37387
SAMD5 sterile alpha motif domain containing 5 3.37387
TPPP3 tubulin polymerization-promoting protein family member 3 3.37387
IRX5 iroquois homeobox 5 3.37387
ZNF503 zinc finger protein 503 3.37387
ADAP1 ArfGAP with dual PH domains 1 3.37387
ADCY10 adenylate cyclase 10 (soluble) 3.37387
WFDC11 WAP four-disulfide core domain 11 3.37387
GRM6 glutamate receptor, metabotropic 6 3.37387
ESPNL espin-like 3.37387
SMCO3 single-pass membrane protein with coiled-coil domains 3 3.37387
GOLGA8R golgin A8 family, member R 3.37387
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 3.37387
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 3.37387
OR52N5 olfactory receptor, family 52, subfamily N, member 5 3.37387
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 3.37387
CFB complement factor B 3.37387
NMBR neuromedin B receptor 3.37387
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.37387
ACSM2B acyl-CoA synthetase medium-chain family member 2B 3.37387
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.37387
PRH2 proline-rich protein HaeIII subfamily 2 3.37387
TTC36 tetratricopeptide repeat domain 36 3.37387
FRMPD1 FERM and PDZ domain containing 1 3.37387
TGM2 transglutaminase 2 3.37387
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.37387
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 3.37387
CLEC1A C-type lectin domain family 1, member A 3.37387
DCT dopachrome tautomerase 3.37387
NT5C1B 5'-nucleotidase, cytosolic IB 3.37387
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.37387
POU3F4 POU class 3 homeobox 4 3.30161
GOLGA6L7 golgin A6 family like 7 3.30161
ETV7 ets variant 7 3.30161
IGFL4 IGF-like family member 4 3.30161
CBR4 carbonyl reductase 4 3.16349
PNN pinin, desmosome associated protein 3.14698
PCED1B PC-esterase domain containing 1B 3.02595
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 3.02311
IRF2-DT IRF2 divergent transcript 2.94767
C3ORF52 chromosome 3 open reading frame 52 2.93004
RGN regucalcin 2.81267
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 2.81267
VASN vasorin 2.7319
ERAP1 endoplasmic reticulum aminopeptidase 1 2.68119
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2.6435
NPIPA5 nuclear pore complex interacting protein family, member A5 2.55257
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.51719
CLCNKB chloride channel, voltage-sensitive Kb 2.51719
PHF21A PHD finger protein 21A 2.49384
ZNF433 zinc finger protein 433 2.48796
ZNF780B zinc finger protein 780B 2.46706
ASPN asporin 2.46706
GMFG glia maturation factor, gamma 2.44987
SLC22A23 solute carrier family 22, member 23 2.42349
TBC1D12 TBC1 domain family, member 12 2.41392
RNF130 ring finger protein 130 2.40746
MARCHF2 membrane associated ring-CH-type finger 2 2.40581
TARBP1 TAR (HIV-1) RNA binding protein 1 2.40581
KLF4 Kruppel-like factor 4 (gut) 2.40581
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 2.39153
KLHL32 kelch-like family member 32 2.35183
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 2.34179
TPPP2 tubulin polymerization-promoting protein family member 2 2.34179
SP140 SP140 nuclear body protein 2.34179
CRIP2 cysteine-rich protein 2 2.34179
MPPED1 metallophosphoesterase domain containing 1 2.34179
PRDM7 PR domain containing 7 2.34179
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 2.34179
EXTL1 exostosin-like glycosyltransferase 1 2.34179
MYO7A myosin VIIA 2.34179
TTC16 tetratricopeptide repeat domain 16 2.32383
SLC45A4 solute carrier family 45, member 4 2.32383
RHOBTB1 Rho-related BTB domain containing 1 2.30888
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 2.28648
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.22995
TMEM35B transmembrane protein 35B 2.22995
REC8 REC8 meiotic recombination protein 2.22229
L3MBTL2 l(3)mbt-like 2 (Drosophila) 2.22157
MCU mitochondrial calcium uniporter 2.21515
DVL2 dishevelled segment polarity protein 2 2.21169
SETD2 SET domain containing 2 2.20874
DISP3 dispatched RND transporter family member 3 2.11148
MPND MPN domain containing 2.06767
CCDC90B coiled-coil domain containing 90B 2.06767
SLC66A2 solute carrier family 66 member 2 2.05093
ZNF142 zinc finger protein 142 2.04816
PABIR2 PABIR family member 2 2.02381
UIMC1 ubiquitin interaction motif containing 1 2.02381
AMMECR1L AMMECR1-like 2.02087
CHD1 chromodomain helicase DNA binding protein 1 2.01756
ZNF442 zinc finger protein 442 2.01658
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.00789

decreased expression

Symbol Name Standardized Value
C20ORF204 chromosome 20 open reading frame 204 -3.37387
TTLL2 tubulin tyrosine ligase-like family member 2 -3.37387
IDUA iduronidase, alpha-L- -3.37387
CRYGB crystallin, gamma B -3.37387
FAM181B family with sequence similarity 181, member B -3.37387
TSPAN8 tetraspanin 8 -3.37387
DSPP dentin sialophosphoprotein -3.37387
SPDYE2B speedy/RINGO cell cycle regulator family member E2B -3.37387
BIN2 bridging integrator 2 -3.37387
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae) -3.37387
CLIC5 chloride intracellular channel 5 -3.37387
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -3.37387
MUSK muscle, skeletal, receptor tyrosine kinase -3.37387
SGPP2 sphingosine-1-phosphate phosphatase 2 -3.37387
MYOCOS myocilin opposite strand -3.37387
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough -3.37387
CSAG3 CSAG family, member 3 -3.37387
MROH5 maestro heat-like repeat family member 5 -3.37387
SYCP2 synaptonemal complex protein 2 -3.37387
KLHL34 kelch-like family member 34 -3.37387
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -3.37387
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 -3.37387
C11ORF52 chromosome 11 open reading frame 52 -3.37387
PEAR1 platelet endothelial aggregation receptor 1 -3.37387
ANKRD63 ankyrin repeat domain 63 -3.37387
KLF9 Kruppel-like factor 9 -3.37387
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -3.37387
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) -3.37387
CCDC73 coiled-coil domain containing 73 -3.37387
EPHA10 EPH receptor A10 -3.37387
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -3.37387
IP6K3 inositol hexakisphosphate kinase 3 -3.37387
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -3.37387
CLEC4G C-type lectin domain family 4, member G -3.37387
CCDC177 coiled-coil domain containing 177 -3.37387
SPINK9 serine peptidase inhibitor, Kazal type 9 -3.37387
NLRP14 NLR family, pyrin domain containing 14 -3.37387
SIDT1 SID1 transmembrane family, member 1 -3.37387
ZNF747 zinc finger protein 747 -3.35952
AFAP1L2 actin filament associated protein 1-like 2 -3.30401
ADGRA2 adhesion G protein-coupled receptor A2 -3.2606
ASIC2 acid sensing (proton gated) ion channel 2 -3.23982
PLA2R1 phospholipase A2 receptor 1, 180kDa -3.23865
EMC8 ER membrane protein complex subunit 8 -3.14698
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -3.14698
TRMT61A tRNA methyltransferase 61A -3.13102
DUSP28 dual specificity phosphatase 28 -3.11664
SNX22 sorting nexin 22 -3.11154
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -3.07877
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.96801
S100A10 S100 calcium binding protein A10 -2.81093
MEDAG mesenteric estrogen-dependent adipogenesis -2.75015
GVQW3 GVQW motif containing 3 -2.64778
ANO8 anoctamin 8 -2.54256
HEATR5B HEAT repeat containing 5B -2.51719
ARMC9 armadillo repeat containing 9 -2.49384
HTRA1 HtrA serine peptidase 1 -2.47943
RECK reversion-inducing-cysteine-rich protein with kazal motifs -2.46706
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 -2.45212
CNR1 cannabinoid receptor 1 (brain) -2.45212
CLEC16A C-type lectin domain family 16, member A -2.44987
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -2.43819
RNF214 ring finger protein 214 -2.42671
LRMDA leucine rich melanocyte differentiation associated -2.41228
NCR1 natural cytotoxicity triggering receptor 1 -2.40581
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) -2.40225
PALLD palladin, cytoskeletal associated protein -2.3959
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -2.38882
CENPO centromere protein O -2.3829
PALB2 partner and localizer of BRCA2 -2.36606
DIAPH1 diaphanous-related formin 1 -2.35183
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit -2.34179
TMEM213 transmembrane protein 213 -2.34179
PEX12 peroxisomal biogenesis factor 12 -2.34179
UBXN2B UBX domain protein 2B -2.33493
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -2.32383
NFX1 nuclear transcription factor, X-box binding 1 -2.28913
C17ORF114 chromosome 17 open reading frame 114 -2.28908
SGSH N-sulfoglucosamine sulfohydrolase -2.28908
CRHR2 corticotropin releasing hormone receptor 2 -2.28908
RNLS renalase, FAD-dependent amine oxidase -2.28648
IL17C interleukin 17C -2.28023
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.28023
KYNU kynureninase -2.28023
CPM carboxypeptidase M -2.28023
ARG1 arginase 1 -2.2407
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -2.23276
WIPI2 WD repeat domain, phosphoinositide interacting 2 -2.22995
THBS4 thrombospondin 4 -2.22995
ANK1 ankyrin 1, erythrocytic -2.20874
RTL8A retrotransposon Gag like 8A -2.20663
KPTN kaptin (actin binding protein) -2.19208
BCL2L14 BCL2-like 14 (apoptosis facilitator) -2.16304
ZNF586 zinc finger protein 586 -2.15958
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.15958
DHCR7 7-dehydrocholesterol reductase -2.15958
GCN1 GCN1 activator of EIF2AK4 -2.15026
DCX doublecortin -2.1461
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -2.10312
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -2.09529
HDAC3 histone deacetylase 3 -2.0892
USP22 ubiquitin specific peptidase 22 -2.0779
GRM4 glutamate receptor, metabotropic 4 -2.04919
RSRC2 arginine/serine-rich coiled-coil 2 -2.04919
GDI1 GDP dissociation inhibitor 1 -2.02264
RNGTT RNA guanylyltransferase and 5'-phosphatase -2.00773
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 -2.00073