S100A11 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description S100 calcium binding protein A11|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6282)
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Genes

277 genes differentially expressed following the S100A11 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHGA11 protocadherin gamma subfamily A, 11 2.70758
TTC16 tetratricopeptide repeat domain 16 2.70758
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.70758
OR51M1 olfactory receptor, family 51, subfamily M, member 1 2.70758
ZEB2 zinc finger E-box binding homeobox 2 2.70758
TAL2 T-cell acute lymphocytic leukemia 2 2.70758
BEST3 bestrophin 3 2.70758
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 2.70758
TLR9 toll-like receptor 9 2.70758
HACD1 3-hydroxyacyl-CoA dehydratase 1 2.70758
C17ORF58 chromosome 17 open reading frame 58 2.70758
BPIFC BPI fold containing family C 2.70758
TIGD3 tigger transposable element derived 3 2.70758
TRADD TNFRSF1A-associated via death domain 2.70758
DAND5 DAN domain family member 5, BMP antagonist 2.70758
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.70758
FNDC1 fibronectin type III domain containing 1 2.70758
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 2.70758
RNF227 ring finger protein 227 2.70758
DNAH8 dynein, axonemal, heavy chain 8 2.70758
DMP1 dentin matrix acidic phosphoprotein 1 2.70758
MORC1 MORC family CW-type zinc finger 1 2.70758
OTOP2 otopetrin 2 2.70758
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.70758
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.70758
SPDEF SAM pointed domain containing ETS transcription factor 2.70758
ECRG4 ECRG4 augurin precursor 2.55364
GJA3 gap junction protein, alpha 3, 46kDa 2.51074
AGTR1 angiotensin II receptor, type 1 2.51074
CLEC12A C-type lectin domain family 12, member A 2.51074
LRRD1 leucine-rich repeats and death domain containing 1 2.51074
GFRA4 GDNF family receptor alpha 4 2.51074
ALB albumin 2.51074
SACK1E scaffolding CK1 anchoring protein E 2.51074
PCDHGB3 protocadherin gamma subfamily B, 3 2.51074
SIRPB2 signal-regulatory protein beta 2 2.51074
C1GALT1C1L C1GALT1-specific chaperone 1 like 2.51074
S100A2 S100 calcium binding protein A2 2.51074
LGI1 leucine-rich, glioma inactivated 1 2.51074
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.51074
ZNF556 zinc finger protein 556 2.51074
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.51074
BSX brain-specific homeobox 2.51074
NRROS negative regulator of reactive oxygen species 2.51074
RFPL3 ret finger protein-like 3 2.51074
TNIP3 TNFAIP3 interacting protein 3 2.51074
GIMAP4 GTPase, IMAP family member 4 2.51074
MYOM2 myomesin 2 2.51074
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.51074
SIGLEC7 sialic acid binding Ig-like lectin 7 2.51074
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 2.51074
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.51074
HBM hemoglobin, mu 2.51074
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.51074
SYCP2 synaptonemal complex protein 2 2.51074
WNT9B wingless-type MMTV integration site family, member 9B 2.51074
OR7D2 olfactory receptor, family 7, subfamily D, member 2 2.51074
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.51074
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.51074
MUSTN1 musculoskeletal, embryonic nuclear protein 1 2.51074
SPRR2A small proline-rich protein 2A 2.51074
STX11 syntaxin 11 2.51074
RD3 retinal degeneration 3 2.51074
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.51074
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.51074
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 2.51074
VSIR V-set immunoregulatory receptor 2.51074
CLXN calaxin 2.51074
CFAP119 cilia and flagella associated protein 119 2.51074
CGB3 chorionic gonadotropin subunit beta 3 2.51074
H2BW1 H2B.W histone 1 2.51074
TMEM270 transmembrane protein 270 2.51074
ZAR1L zygote arrest 1-like 2.51074
LRRC72 leucine rich repeat containing 72 2.51074
KLHL38 kelch-like family member 38 2.51074
PTPRH protein tyrosine phosphatase, receptor type, H 2.51074
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 2.51074
VGLL2 vestigial-like family member 2 2.51074
CLDN9 claudin 9 2.51074
TRIM60 tripartite motif containing 60 2.51074
CLEC3A C-type lectin domain family 3, member A 2.51074
OLAH oleoyl-ACP hydrolase 2.51074
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.51074
DMBX1 diencephalon/mesencephalon homeobox 1 2.51074
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.51074
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.51074
SPDYC speedy/RINGO cell cycle regulator family member C 2.51074
GSC goosecoid homeobox 2.51074
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.51074
UTS2 urotensin 2 2.51074
FGFBP2 fibroblast growth factor binding protein 2 2.51074
SPATA31F1 SPATA31 subfamily F member 1 2.51074
TTC9B tetratricopeptide repeat domain 9B 2.51074
TIGIT T cell immunoreceptor with Ig and ITIM domains 2.51074
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.51074
EGR2 early growth response 2 2.51074
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 2.51074
PDCD1 programmed cell death 1 2.51074
AGR3 anterior gradient 3 2.51074
MC5R melanocortin 5 receptor 2.51074
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.51074
ASTL astacin-like metallo-endopeptidase (M12 family) 2.51074
CARD6 caspase recruitment domain family, member 6 2.51074
EPO erythropoietin 2.51074
AMER2 APC membrane recruitment protein 2 2.51074
FSHR follicle stimulating hormone receptor 2.51074
HHIPL2 HHIP-like 2 2.51074
A3GALT2 alpha 1,3-galactosyltransferase 2 2.51074
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 2.51074
COMP cartilage oligomeric matrix protein 2.51074
CDH10 cadherin 10, type 2 (T2-cadherin) 2.51074
CPA3 carboxypeptidase A3 (mast cell) 2.51074
BPIFB1 BPI fold containing family B, member 1 2.51074
FAM163A family with sequence similarity 163, member A 2.51074
HSPA1L heat shock 70kDa protein 1-like 2.51074
CTAGE9 CTAGE family, member 9 2.51074
SPATA31E1 SPATA31 subfamily E, member 1 2.51074
CRYBB2 crystallin, beta B2 2.51074
ETNPPL ethanolamine-phosphate phospho-lyase 2.51074
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 2.51074
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 2.51074
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 2.51074
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 2.51074
APOL6 apolipoprotein L, 6 2.51074
ITGA10 integrin, alpha 10 2.51074
NLRP9 NLR family, pyrin domain containing 9 2.51074
IBSP integrin-binding sialoprotein 2.51074
MAGEC3 melanoma antigen family C3 2.51074
CTRB1 chymotrypsinogen B1 2.51074
HMGB4 high mobility group box 4 2.51074
CLEC18B C-type lectin domain family 18, member B 2.51074
TMEM255A transmembrane protein 255A 2.51074
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.51074
BOLA2 bolA family member 2 2.51074
NMUR2 neuromedin U receptor 2 2.51074
NCR2 natural cytotoxicity triggering receptor 2 2.51074
GJC2 gap junction protein, gamma 2, 47kDa 2.51074
LRRC26 leucine rich repeat containing 26 2.51074
CLEC14A C-type lectin domain family 14, member A 2.51074
LRRC38 leucine rich repeat containing 38 2.51074
KIF12 kinesin family member 12 2.51074
TMEM45B transmembrane protein 45B 2.51074
SCNN1A sodium channel, non voltage gated 1 alpha subunit 2.51074
TMPRSS13 transmembrane protease, serine 13 2.51074
TMPRSS15 transmembrane protease, serine 15 2.51074
GRAPL GRB2-related adaptor protein-like 2.51074
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.51074
VAV1 vav 1 guanine nucleotide exchange factor 2.51074
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.51074
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.51074
MMP12 matrix metallopeptidase 12 2.51074
SLC38A5 solute carrier family 38, member 5 2.51074
FOXG1 forkhead box G1 2.51074
ZNF226 zinc finger protein 226 2.51011
VWC2L von Willebrand factor C domain containing protein 2-like 2.50565
LIX1L Lix1 homolog (chicken) like 2.50565
CD52 CD52 molecule 2.48729
ACTA1 actin, alpha 1, skeletal muscle 2.48729
NLRC3 NLR family, CARD domain containing 3 2.48729
CRYM crystallin, mu 2.45715
VRK2 vaccinia related kinase 2 2.41364
SLC26A6 solute carrier family 26 (anion exchanger), member 6 2.39419
LAMA1 laminin, alpha 1 2.39419
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.35221
CORO6 coronin 6 2.3282
ANKRD42-DT ANKRD42 divergent transcript 2.3282
VEGFD vascular endothelial growth factor D 2.30344
ZFP92 ZFP92 zinc finger protein 2.30344
COL4A5 collagen, type IV, alpha 5 2.30007
KDM4B lysine (K)-specific demethylase 4B 2.28187
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.25798
AASS aminoadipate-semialdehyde synthase 2.25222
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.24985
NCKIPSD NCK interacting protein with SH3 domain 2.19587
RABL2A RAB, member of RAS oncogene family-like 2A 2.19244
SCN4B sodium channel, voltage gated, type IV beta subunit 2.18329
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 2.17196
ZNF8 zinc finger protein 8 2.15473
TSBP1 testis expressed basic protein 1 2.15473
PRUNE1 prune exopolyphosphatase 1 2.15396
GARNL3 GTPase activating Rap/RanGAP domain-like 3 2.15396
CA10 carbonic anhydrase X 2.14964
FBXW8 F-box and WD repeat domain containing 8 2.14256
CCDC3 coiled-coil domain containing 3 2.11146
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.10028
ZNF713 zinc finger protein 713 2.0975
PTK2B protein tyrosine kinase 2 beta 2.08313
IRF2BP2 interferon regulatory factor 2 binding protein 2 2.06833
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 2.06833
CHMP1A charged multivesicular body protein 1A 2.04667
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.04667
RGN regucalcin 2.04621
EHBP1L1 EH domain binding protein 1-like 1 2.01462
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 2.01447
ZC3H12B zinc finger CCCH-type containing 12B 2.0066
DPY19L3 dpy-19-like 3 (C. elegans) 2.00129

decreased expression

Symbol Name Standardized Value
PYCR3 pyrroline-5-carboxylate reductase 3 -2.70758
SHOX short stature homeobox -2.70758
ZBTB35 zinc finger and BTB domain containing 35 -2.70758
S100A11 S100 calcium binding protein A11 -2.70758
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -2.65976
DNAI2 dynein, axonemal, intermediate chain 2 -2.65976
IRF4 interferon regulatory factor 4 -2.65976
CNGA4 cyclic nucleotide gated channel alpha 4 -2.65976
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -2.57056
THUMPD2 THUMP domain containing 2 -2.51074
TMEM121 transmembrane protein 121 -2.51074
MRO maestro -2.51074
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.51074
ASGR2 asialoglycoprotein receptor 2 -2.51074
SMIM41 small integral membrane protein 41 -2.51074
ZNF804B zinc finger protein 804B -2.51074
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 -2.51074
A1CF APOBEC1 complementation factor -2.51074
CCDC38 coiled-coil domain containing 38 -2.51074
FRK fyn-related Src family tyrosine kinase -2.51074
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -2.51074
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -2.51074
SIX4 SIX homeobox 4 -2.51074
TRAP1 TNF receptor-associated protein 1 -2.51074
TRIM15 tripartite motif containing 15 -2.51074
CCL5 chemokine (C-C motif) ligand 5 -2.51074
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -2.51074
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -2.51074
TMEM235 transmembrane protein 235 -2.51074
S100G S100 calcium binding protein G -2.51074
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.51074
IP6K3 inositol hexakisphosphate kinase 3 -2.51074
ALAS2 5'-aminolevulinate synthase 2 -2.51074
TCAP titin-cap -2.51074
PRAM1 PML-RARA regulated adaptor molecule 1 -2.51074
SCUBE1 signal peptide, CUB domain, EGF-like 1 -2.51074
STAT5A signal transducer and activator of transcription 5A -2.51074
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -2.51074
CRHR1 corticotropin releasing hormone receptor 1 -2.51074
CFP complement factor properdin -2.51074
BAHCC1 BAH domain and coiled-coil containing 1 -2.51074
ZNF695 zinc finger protein 695 -2.51011
CD38 CD38 molecule -2.50565
SLC44A4 solute carrier family 44, member 4 -2.50565
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -2.50451
C10ORF95 chromosome 10 open reading frame 95 -2.46434
PRKD2 protein kinase D2 -2.45715
C4ORF51 chromosome 4 open reading frame 51 -2.39923
TST thiosulfate sulfurtransferase (rhodanese) -2.36179
APOM apolipoprotein M -2.36036
INSL3 insulin-like 3 (Leydig cell) -2.35221
FOXO3B forkhead box O3B pseudogene -2.34075
ASRGL1 asparaginase like 1 -2.30671
TMEM161B transmembrane protein 161B -2.30007
MPI mannose phosphate isomerase -2.30007
ZNF341 zinc finger protein 341 -2.28187
ATF7 activating transcription factor 7 -2.27784
TMPO thymopoietin -2.27784
USP28 ubiquitin specific peptidase 28 -2.26155
CELF2 CUGBP, Elav-like family member 2 -2.25505
AKAP11 A kinase (PRKA) anchor protein 11 -2.1994
PHGDH phosphoglycerate dehydrogenase -2.19938
SETD9 SET domain containing 9 -2.19587
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -2.17196
EXT2 exostosin glycosyltransferase 2 -2.16436
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.15695
FEN1 flap structure-specific endonuclease 1 -2.15396
UNC119 unc-119 homolog (C. elegans) -2.14964
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -2.10028
TUBA8 tubulin, alpha 8 -2.09988
NRBP2 nuclear receptor binding protein 2 -2.09984
MPC2 mitochondrial pyruvate carrier 2 -2.09948
ZNF143 zinc finger protein 143 -2.07505
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.07279
MGARP mitochondria-localized glutamic acid-rich protein -2.06833
VMAC vimentin-type intermediate filament associated coiled-coil protein -2.03048
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.03048
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -2.02946
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -2.01462
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.00129
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 -2.00129