S100A8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description S100 calcium binding protein A8|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6279)
External Link https://ncbi.nlm.nih.gov/gene/6279
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Genes

499 genes differentially expressed following the S100A8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 0.0140009
MAP7 microtubule-associated protein 7 0.0129945
S100A8 S100 calcium binding protein A8 0.0118961
HOPX HOP homeobox 0.0110935
RAD23B RAD23 homolog B (S. cerevisiae) 0.0103777
CKS2 CDC28 protein kinase regulatory subunit 2 0.0103696
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0102023
SLC38A1 solute carrier family 38, member 1 0.00977303
TFRC transferrin receptor 0.00966779
H1-0 H1.0 linker histone 0.00964153
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00947152
CA2 carbonic anhydrase II 0.0094162
MBD1 methyl-CpG binding domain protein 1 0.00928046
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00913165
CXCL13 chemokine (C-X-C motif) ligand 13 0.00901891
IL1RN interleukin 1 receptor antagonist 0.00871863
PSD3 pleckstrin and Sec7 domain containing 3 0.00857744
WSB1 WD repeat and SOCS box containing 1 0.00856081
AMIGO2 adhesion molecule with Ig-like domain 2 0.00830362
NPR3 natriuretic peptide receptor 3 0.00830225
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00824077
MTUS1 microtubule associated tumor suppressor 1 0.00820274
NELL1 NEL-like 1 (chicken) 0.00807134
PHACTR2 phosphatase and actin regulator 2 0.00800686
CDC20 cell division cycle 20 0.00797189
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00773418
TMEM230 transmembrane protein 230 0.00772632
TPM4 tropomyosin 4 0.00765694
S100P S100 calcium binding protein P 0.00760769
PLK2 polo-like kinase 2 0.00734317
TACSTD2 tumor-associated calcium signal transducer 2 0.00733249
DLG1 discs, large homolog 1 (Drosophila) 0.00726792
PHYH phytanoyl-CoA 2-hydroxylase 0.0072605
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00725617
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00723918
ST18 suppression of tumorigenicity 18, zinc finger 0.0071271
CSTA cystatin A (stefin A) 0.00710793
SHTN1 shootin 1 0.00706036
DCK deoxycytidine kinase 0.00705897
TRAM1 translocation associated membrane protein 1 0.0070156
WASF1 WAS protein family, member 1 0.00698176
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00694657
ANXA3 annexin A3 0.00690951
CD52 CD52 molecule 0.00689388
RNF130 ring finger protein 130 0.00689226
KLF6 Kruppel-like factor 6 0.00684968
PRDX2 peroxiredoxin 2 0.00684169
LYZ lysozyme 0.0066933
DOCK4 dedicator of cytokinesis 4 0.00665896
GUSBP3 glucuronidase, beta pseudogene 3 0.00664917
PTER phosphotriesterase related 0.00664505
RAPSN receptor-associated protein of the synapse 0.00661801
ECHDC2 enoyl CoA hydratase domain containing 2 0.00661545
IFT57 intraflagellar transport 57 0.00661297
VAMP8 vesicle-associated membrane protein 8 0.00656705
DPYSL2 dihydropyrimidinase-like 2 0.00656161
MCL1 myeloid cell leukemia 1 0.00645269
PALLD palladin, cytoskeletal associated protein 0.00644653
PREPL prolyl endopeptidase-like 0.00643555
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00641746
SGPP1 sphingosine-1-phosphate phosphatase 1 0.00641403
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00641339
RAB25 RAB25, member RAS oncogene family 0.00639185
WBP5 WW domain binding protein 5 0.0063849
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00633
CTNND1 catenin (cadherin-associated protein), delta 1 0.00630718
SKAP2 src kinase associated phosphoprotein 2 0.00630285
COL4A5 collagen, type IV, alpha 5 0.00628812
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00627418
MIR22HG MIR22 host gene 0.00627077
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00625047
SH3YL1 SH3 and SYLF domain containing 1 0.00623298
FST follistatin 0.00620684
NDFIP1 Nedd4 family interacting protein 1 0.00618451
CLDN7 claudin 7 0.0061768
ATG3 autophagy related 3 0.00613134
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00612635
CXCL9 chemokine (C-X-C motif) ligand 9 0.00612245
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00610709
SCARB2 scavenger receptor class B, member 2 0.00610267
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0060919
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.0060748
SC5D sterol-C5-desaturase 0.00607291
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00604777
DAPK1 death-associated protein kinase 1 0.00602235
CD46 CD46 molecule, complement regulatory protein 0.00596412
CCNL2 cyclin L2 0.00587925
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00587348
PDGFC platelet derived growth factor C 0.00583928
EXOC5 exocyst complex component 5 0.00583688
ADAMDEC1 ADAM-like, decysin 1 0.00579351
PDCD10 programmed cell death 10 0.00579111
EVI2A ecotropic viral integration site 2A 0.00579069
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0057884
MARCHF7 membrane associated ring-CH-type finger 7 0.00578008
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00575814
SLC31A2 solute carrier family 31 (copper transporter), member 2 0.0057364
LIMCH1 LIM and calponin homology domains 1 0.00573533
ZFP36L1 ZFP36 ring finger protein-like 1 0.0057292
ELANE elastase, neutrophil expressed 0.0057202
RESF1 retroelement silencing factor 1 0.00571518
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00567921
CTBP2 C-terminal binding protein 2 0.00567485
MKKS McKusick-Kaufman syndrome 0.00566593
SPTSSA serine palmitoyltransferase, small subunit A 0.00564994
CLDND1 claudin domain containing 1 0.00563479
DSTN destrin (actin depolymerizing factor) 0.0056325
STX3 syntaxin 3 0.00556021
ABLIM1 actin binding LIM protein 1 0.00554412
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.0055403
EXPH5 exophilin 5 0.00553294
SDC4 syndecan 4 0.00553012
ARMC1 armadillo repeat containing 1 0.00552533
CDKN3 cyclin-dependent kinase inhibitor 3 0.00550384
MARCO macrophage receptor with collagenous structure 0.00547422
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00545494
MYRF myelin regulatory factor 0.00544831
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00543887
RHOB ras homolog family member B 0.00543539
PKP2 plakophilin 2 0.0054334
MN1 meningioma (disrupted in balanced translocation) 1 0.00542933
CAPRIN1 cell cycle associated protein 1 0.00542761
MTCL1 microtubule crosslinking factor 1 0.00541994
LPAR1 lysophosphatidic acid receptor 1 0.00541858
PTS 6-pyruvoyltetrahydropterin synthase 0.00540306
GLRX3 glutaredoxin 3 0.00540037
PERP PERP, TP53 apoptosis effector 0.00538728
ZSCAN18 zinc finger and SCAN domain containing 18 0.00538604
CLC Charcot-Leyden crystal galectin 0.00536473
HBD hemoglobin, delta 0.00533564
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00533481
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00533415
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00532331
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00531312
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00530439
PCNA proliferating cell nuclear antigen 0.00530118
ZNF83 zinc finger protein 83 0.00529018
P3H2 prolyl 3-hydroxylase 2 0.00528968
KRT19 keratin 19, type I 0.00527958
CTSH cathepsin H 0.00525934
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00524324
OSBPL1A oxysterol binding protein-like 1A 0.00524197
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.00523222
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00522913
MEIS1 Meis homeobox 1 0.00520323
TSC22D1 TSC22 domain family, member 1 0.00519947
PRUNE1 prune exopolyphosphatase 1 0.00519591
PON3 paraoxonase 3 0.00517573
PTPRM protein tyrosine phosphatase, receptor type, M 0.00515089
EHF ets homologous factor 0.00514569
TCF21 transcription factor 21 0.00514555
DUSP1 dual specificity phosphatase 1 0.00514004
GJA1 gap junction protein, alpha 1, 43kDa 0.00513924
SRP9 signal recognition particle 9kDa 0.00511615
GPNMB glycoprotein (transmembrane) nmb 0.00510265
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.00510237
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00509483
APMAP adipocyte plasma membrane associated protein 0.00508393
ZNF91 zinc finger protein 91 0.00507607
RDX radixin 0.00507002
DYNLL1 dynein, light chain, LC8-type 1 0.00505207
BTBD3 BTB (POZ) domain containing 3 0.00504458
NRGN neurogranin (protein kinase C substrate, RC3) 0.00501302
CGRRF1 cell growth regulator with ring finger domain 1 0.00499699
LPXN leupaxin 0.00497732
SRSF1 serine/arginine-rich splicing factor 1 0.00494681
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.00494442
SELENOT selenoprotein T 0.00493507
CREB1 cAMP responsive element binding protein 1 0.00492105
SIK1 salt-inducible kinase 1 0.00491
CNOT7 CCR4-NOT transcription complex, subunit 7 0.00490277
HTRA1 HtrA serine peptidase 1 0.00490189
CST3 cystatin C 0.00489907
IL6ST interleukin 6 signal transducer 0.00488325
SPIN1 spindlin 1 0.00486966
CCNG2 cyclin G2 0.0048673
ZNF281 zinc finger protein 281 0.00486397
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.00486379
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00485976
ESRP1 epithelial splicing regulatory protein 1 0.00485537
F13A1 coagulation factor XIII, A1 polypeptide 0.00485355
ANXA4 annexin A4 0.00484958
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00484808
RC3H2 ring finger and CCCH-type domains 2 0.00484273
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00484247
TSPAN6 tetraspanin 6 0.00482647
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00480361
MPO myeloperoxidase 0.00479361
IRF6 interferon regulatory factor 6 0.00477343
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.00477075
WT1 Wilms tumor 1 0.00477049
CD9 CD9 molecule 0.00474973
SPON2 spondin 2, extracellular matrix protein 0.00473002
HOXC6 homeobox C6 0.00472848
TMEM165 transmembrane protein 165 0.00472789
GCA grancalcin, EF-hand calcium binding protein 0.00471307
ATP5MG ATP synthase membrane subunit g 0.0046941
DNALI1 dynein, axonemal, light intermediate chain 1 0.00467922
TMEM126B transmembrane protein 126B 0.00466815
LGALS2 lectin, galactoside-binding, soluble, 2 0.00466743
LXN latexin 0.00466663
YME1L1 YME1-like 1 ATPase 0.00464936
FAM120A family with sequence similarity 120A 0.00463244
CCDC68 coiled-coil domain containing 68 0.0046319
GTPBP8 GTP-binding protein 8 (putative) 0.00463074
ARL8B ADP-ribosylation factor-like 8B 0.00462799
SDC2 syndecan 2 0.0046115
SFRP4 secreted frizzled-related protein 4 0.00460497
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00459964
ZNF331 zinc finger protein 331 0.0045917
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00457843
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00457691
SRSF10 serine/arginine-rich splicing factor 10 0.00457552
SGK1 serum/glucocorticoid regulated kinase 1 0.00457423
LY96 lymphocyte antigen 96 0.00456942
CADM1 cell adhesion molecule 1 0.00456847
GATA6 GATA binding protein 6 0.00456759
ZBED2 zinc finger, BED-type containing 2 0.00456688
GMCL1 germ cell-less, spermatogenesis associated 1 0.00455078
SCG5 secretogranin V 0.00454469
RIN2 Ras and Rab interactor 2 0.00453347
QPCT glutaminyl-peptide cyclotransferase 0.00452164
ANKRD12 ankyrin repeat domain 12 0.00451626
PEG3 paternally expressed 3 0.00450889
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00450662
TGIF1 TGFB-induced factor homeobox 1 0.00450374
MREG melanoregulin 0.00449586
CD200 CD200 molecule 0.0044925
MCM2 minichromosome maintenance complex component 2 0.004487
ATF3 activating transcription factor 3 0.00448644
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00447687
TPD52L1 tumor protein D52-like 1 0.00444821
CYB5R2 cytochrome b5 reductase 2 0.00444695
RAB23 RAB23, member RAS oncogene family 0.00442692
ANPEP alanyl (membrane) aminopeptidase 0.00442476
TMEM260 transmembrane protein 260 0.00442238
ZNF665 zinc finger protein 665 0.00441301
MNDA myeloid cell nuclear differentiation antigen 0.00440239
CDC37L1 cell division cycle 37-like 1 0.004401
RAB38 RAB38, member RAS oncogene family 0.00439405
ADM adrenomedullin 0.00438791
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00438566
TSPAN5 tetraspanin 5 0.00437919
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00437645
YAP1 Yes-associated protein 1 0.00437001
IPO13 importin 13 0.00436122
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00435619
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00434811
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00434345
CD164 CD164 molecule, sialomucin 0.00433959

decreased expression

Symbol Name Standardized Value
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0156507
SYNGR3 synaptogyrin 3 -0.0133844
PUF60 poly-U binding splicing factor 60KDa -0.0133536
APOD apolipoprotein D -0.0130945
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0128307
MAGEA3 melanoma antigen family A3 -0.0125655
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0123359
OXTR oxytocin receptor -0.0114601
CRYBG1 crystallin beta-gamma domain containing 1 -0.0112283
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0104019
NEFH neurofilament, heavy polypeptide -0.0100634
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00952629
AQP3 aquaporin 3 (Gill blood group) -0.00935228
KRT15 keratin 15, type I -0.00911733
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00883711
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00880684
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00797839
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0079715
SCGB2A2 secretoglobin, family 2A, member 2 -0.00795923
KIAA0355 KIAA0355 -0.00795732
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00785284
HEATR1 HEAT repeat containing 1 -0.00773928
PRKCA protein kinase C, alpha -0.00772726
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0076535
PI3 peptidase inhibitor 3, skin-derived -0.00752935
NELL2 NEL-like 2 (chicken) -0.00747146
KRT14 keratin 14, type I -0.00740828
TFF3 trefoil factor 3 (intestinal) -0.00739463
DLK1 delta-like 1 homolog (Drosophila) -0.00726814
MSX1 msh homeobox 1 -0.00724088
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0072322
ISG15 ISG15 ubiquitin-like modifier -0.00717466
BEX1 brain expressed, X-linked 1 -0.00709457
MT1X metallothionein 1X -0.0070758
SORBS1 sorbin and SH3 domain containing 1 -0.00707572
AQP1 aquaporin 1 (Colton blood group) -0.00706658
PTN pleiotrophin -0.00705431
OASL 2'-5'-oligoadenylate synthetase-like -0.00704967
S100A7 S100 calcium binding protein A7 -0.00703791
FXYD5 FXYD domain containing ion transport regulator 5 -0.00701233
MAGEA12 melanoma antigen family A12 -0.00700563
SYNM synemin, intermediate filament protein -0.00696618
TGFBR3 transforming growth factor, beta receptor III -0.00694807
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00693581
L1CAM L1 cell adhesion molecule -0.00689471
PRAME preferentially expressed antigen in melanoma -0.00687024
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00682722
FGB fibrinogen beta chain -0.00679387
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00675507
SCRIB scribbled planar cell polarity protein -0.00664975
RALB v-ral simian leukemia viral oncogene homolog B -0.00664016
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00663982
MAN1C1 mannosidase, alpha, class 1C, member 1 -0.00656711
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00655179
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00652085
IFI44L interferon-induced protein 44-like -0.00647616
KDM5D lysine (K)-specific demethylase 5D -0.00646211
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00644982
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00644672
OLFM1 olfactomedin 1 -0.00644388
C3 complement component 3 -0.00641925
TMEM255A transmembrane protein 255A -0.00633364
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00625509
QPRT quinolinate phosphoribosyltransferase -0.00624609
XPO7 exportin 7 -0.00620456
MAGED2 melanoma antigen family D2 -0.0061884
VWF von Willebrand factor -0.00616248
LAGE3 L antigen family, member 3 -0.00614597
A2M alpha-2-macroglobulin -0.00612771
PODXL podocalyxin-like -0.00609537
BAG3 BCL2-associated athanogene 3 -0.00607709
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00603474
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00598785
CLDN5 claudin 5 -0.00597667
PITX3 paired-like homeodomain 3 -0.0059388
MCAM melanoma cell adhesion molecule -0.0059382
SRPX sushi-repeat containing protein, X-linked -0.00588481
CFD complement factor D (adipsin) -0.00585811
ANO10 anoctamin 10 -0.00584283
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00582429
FGF13 fibroblast growth factor 13 -0.00582428
IFI27 interferon, alpha-inducible protein 27 -0.00582262
SLC38A10 solute carrier family 38, member 10 -0.00581803
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00580342
GLDC glycine dehydrogenase (decarboxylating) -0.00579765
LRP4 low density lipoprotein receptor-related protein 4 -0.00578709
MX1 MX dynamin-like GTPase 1 -0.00575251
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00575108
AGTR1 angiotensin II receptor, type 1 -0.00574214
JMJD6 jumonji domain containing 6 -0.00574099
RBM34 RNA binding motif protein 34 -0.00572932
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00570046
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00569062
RPN2 ribophorin II -0.00567476
NES nestin -0.00567013
C8ORF33 chromosome 8 open reading frame 33 -0.00566225
NID1 nidogen 1 -0.00565274
PIP prolactin-induced protein -0.00562827
CNN1 calponin 1, basic, smooth muscle -0.00560919
FTSJ3 FtsJ homolog 3 (E. coli) -0.00560116
XBP1 X-box binding protein 1 -0.00558988
KAT7 K(lysine) acetyltransferase 7 -0.00558248
RUNX3 runt-related transcription factor 3 -0.00556117
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00555616
VGF VGF nerve growth factor inducible -0.00555307
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00555176
MDK midkine (neurite growth-promoting factor 2) -0.0055416
TXNIP thioredoxin interacting protein -0.00553048
CYC1 cytochrome c-1 -0.00552366
LMOD1 leiomodin 1 (smooth muscle) -0.00551026
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00550685
FCGBP Fc fragment of IgG binding protein -0.00550076
FKBP11 FK506 binding protein 11, 19 kDa -0.00549766
STK10 serine/threonine kinase 10 -0.00546125
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.0054524
WIF1 WNT inhibitory factor 1 -0.00543544
GAL galanin/GMAP prepropeptide -0.00541949
COQ8A coenzyme Q8A -0.00540231
ENO2 enolase 2 (gamma, neuronal) -0.00535184
PDZK1IP1 PDZK1 interacting protein 1 -0.00529925
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00529798
DEFA5 defensin, alpha 5, Paneth cell-specific -0.00529282
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00528917
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00528343
FGG fibrinogen gamma chain -0.00528237
KRT5 keratin 5, type II -0.00527322
DMD dystrophin -0.00526758
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00524647
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00523408
NOTCH3 notch 3 -0.0052148
BOP1 block of proliferation 1 -0.00518494
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00518079
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00517635
IFI6 interferon, alpha-inducible protein 6 -0.00514923
COCH cochlin -0.00509934
PNOC prepronociceptin -0.00509808
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00509682
MX2 MX dynamin-like GTPase 2 -0.00509479
DPEP1 dipeptidase 1 (renal) -0.00508649
MYH11 myosin, heavy chain 11, smooth muscle -0.00508646
CCL5 chemokine (C-C motif) ligand 5 -0.00506987
AKAP12 A kinase (PRKA) anchor protein 12 -0.00506187
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00505588
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00505132
HIP1R huntingtin interacting protein 1 related -0.00503701
MYO1C myosin IC -0.00503636
DCLK1 doublecortin-like kinase 1 -0.00502168
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.00502052
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00501681
MIA melanoma inhibitory activity -0.00500795
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00497728
APOLD1 apolipoprotein L domain containing 1 -0.00496983
COPG1 coatomer protein complex, subunit gamma 1 -0.00496271
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00495684
TWIST1 twist family bHLH transcription factor 1 -0.00493101
IFI35 interferon-induced protein 35 -0.00493098
C10ORF10 chromosome 10 open reading frame 10 -0.00488584
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -0.00487985
LEPR leptin receptor -0.0048536
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -0.00485353
GNAS GNAS complex locus -0.00484954
FGFR3 fibroblast growth factor receptor 3 -0.0048388
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00481914
PFKL phosphofructokinase, liver -0.00481616
MXRA7 matrix-remodelling associated 7 -0.00480355
ILVBL ilvB (bacterial acetolactate synthase)-like -0.00478227
PTDSS1 phosphatidylserine synthase 1 -0.00477108
CRABP2 cellular retinoic acid binding protein 2 -0.00476245
RHBDF2 rhomboid 5 homolog 2 (Drosophila) -0.00476215
PSCA prostate stem cell antigen -0.00475436
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00474169
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00470941
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00470823
NDRG1 N-myc downstream regulated 1 -0.00469885
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00469762
RGS16 regulator of G-protein signaling 16 -0.00469196
IFITM1 interferon induced transmembrane protein 1 -0.00469094
IGF1R insulin-like growth factor 1 receptor -0.0046861
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00468475
TAPBP TAP binding protein (tapasin) -0.0046764
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00464128
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00463424
NOP14 NOP14 nucleolar protein -0.0046253
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00462518
SORBS2 sorbin and SH3 domain containing 2 -0.00461336
GAS2 growth arrest-specific 2 -0.00460807
MYRIP myosin VIIA and Rab interacting protein -0.00459587
CREBBP CREB binding protein -0.00459539
JAG2 jagged 2 -0.00458087
STC1 stanniocalcin 1 -0.00458042
HIC2 hypermethylated in cancer 2 -0.00457549
CH25H cholesterol 25-hydroxylase -0.00457417
NRN1 neuritin 1 -0.00457173
RGS5 regulator of G-protein signaling 5 -0.00456856
MAGEA1 melanoma antigen family A1 -0.00454945
FLNC filamin C, gamma -0.00454419
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0045396
DNMBP dynamin binding protein -0.00453659
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.0045336
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00453275
LAMA4 laminin, alpha 4 -0.00452844
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00452704
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00451707
BRD8 bromodomain containing 8 -0.00449185
ANGPT2 angiopoietin 2 -0.00449133
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -0.00448664
NANS N-acetylneuraminic acid synthase -0.00447974
BASP1 brain abundant, membrane attached signal protein 1 -0.00447578
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00446318
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00444077
S1PR1 sphingosine-1-phosphate receptor 1 -0.00443924
REEP1 receptor accessory protein 1 -0.0044392
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.00443298
GBP2 guanylate binding protein 2, interferon-inducible -0.0044305
IFI44 interferon-induced protein 44 -0.00441677
PABPC3 poly(A) binding protein, cytoplasmic 3 -0.00440744
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.00440638
DEFA6 defensin, alpha 6, Paneth cell-specific -0.00439835
ARHGAP17 Rho GTPase activating protein 17 -0.00438286
BCHE butyrylcholinesterase -0.00437882
PDE8B phosphodiesterase 8B -0.0043596
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -0.00435939
CRISP3 cysteine-rich secretory protein 3 -0.00435669
DGAT1 diacylglycerol O-acyltransferase 1 -0.00434886
TEAD4 TEA domain family member 4 -0.00434391
NCOR2 nuclear receptor corepressor 2 -0.00434282
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00432718
SP110 SP110 nuclear body protein -0.004325
FZD10 frizzled class receptor 10 -0.00432158
RTN1 reticulon 1 -0.00431541
WFS1 Wolfram syndrome 1 (wolframin) -0.00431523
LGALS9 lectin, galactoside-binding, soluble, 9 -0.00431147
CDK4 cyclin-dependent kinase 4 -0.00431008
PGF placental growth factor -0.0043001
CLU clusterin -0.00429948
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00429269
TNS1 tensin 1 -0.00428837
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00427882
FASN fatty acid synthase -0.0042761
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0042718
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00427071
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.00427061
KDM3B lysine (K)-specific demethylase 3B -0.00425509
SYT11 synaptotagmin XI -0.00425491
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00424685
CP ceruloplasmin (ferroxidase) -0.00424192
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.00423912
DES desmin -0.00423236
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0042288