S100Z Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description S100 calcium binding protein Z|Members of the S100 protein family contain 2 calcium-binding EF-hands and exhibit cell-type specific expression patterns. For additional background information on S100 proteins, see MIM 114085.[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 170591)
External Link https://ncbi.nlm.nih.gov/gene/170591
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Genes

497 genes differentially expressed following the S100Z gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 0.0186897
CD36 CD36 molecule (thrombospondin receptor) 0.0113293
PLN phospholamban 0.0108733
ASPN asporin 0.0106654
FASN fatty acid synthase 0.00984549
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00937575
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00903736
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00897541
MBD1 methyl-CpG binding domain protein 1 0.00893517
RAPSN receptor-associated protein of the synapse 0.008879
ENO2 enolase 2 (gamma, neuronal) 0.00872103
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00861703
SORD sorbitol dehydrogenase 0.00854574
GNAS GNAS complex locus 0.00853101
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00826614
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00815425
COL10A1 collagen, type X, alpha 1 0.00810087
DACH1 dachshund family transcription factor 1 0.00804044
PDLIM3 PDZ and LIM domain 3 0.0080229
NELL2 NEL-like 2 (chicken) 0.00793557
RNASEH2A ribonuclease H2, subunit A 0.00787627
COMP cartilage oligomeric matrix protein 0.00774966
LAMP5 lysosomal-associated membrane protein family, member 5 0.0077428
CPVL carboxypeptidase, vitellogenic-like 0.00772134
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00767464
CXCL14 chemokine (C-X-C motif) ligand 14 0.0076385
INSM1 insulinoma-associated 1 0.00760862
GGCT gamma-glutamylcyclotransferase 0.00754291
SRSF1 serine/arginine-rich splicing factor 1 0.00745052
BCHE butyrylcholinesterase 0.00743471
SORBS1 sorbin and SH3 domain containing 1 0.0074237
ASF1B anti-silencing function 1B histone chaperone 0.00738598
CNN1 calponin 1, basic, smooth muscle 0.00731396
CALD1 caldesmon 1 0.00721157
BGN biglycan 0.007178
CD200 CD200 molecule 0.00716451
STK10 serine/threonine kinase 10 0.00716087
COQ8A coenzyme Q8A 0.00710846
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.00709842
GSTT1 glutathione S-transferase theta 1 0.00709483
ACAT2 acetyl-CoA acetyltransferase 2 0.00708169
C7 complement component 7 0.00700347
INSIG1 insulin induced gene 1 0.00699912
LYZ lysozyme 0.00697026
H2AZ1 H2A.Z variant histone 1 0.00691363
PGAM1 phosphoglycerate mutase 1 (brain) 0.00690943
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00689965
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00689267
PHF10 PHD finger protein 10 0.00688618
FOXM1 forkhead box M1 0.00687895
KDM5D lysine (K)-specific demethylase 5D 0.006868
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.00682909
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00681538
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00677342
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0067546
SLC2A4RG SLC2A4 regulator 0.00668736
DHCR7 7-dehydrocholesterol reductase 0.00667241
GSTO1 glutathione S-transferase omega 1 0.00667077
BIRC5 baculoviral IAP repeat containing 5 0.00666392
DHFR dihydrofolate reductase 0.00665799
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00664709
STON1 stonin 1 0.00662779
MTARC1 mitochondrial amidoxime reducing component 1 0.00661046
PODXL podocalyxin-like 0.00659949
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00659568
NSL1 NSL1, MIS12 kinetochore complex component 0.00657089
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00656424
GATA6 GATA binding protein 6 0.00654107
TMSB15A thymosin beta 15a 0.00653391
AURKB aurora kinase B 0.00645814
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00644559
FXYD6 FXYD domain containing ion transport regulator 6 0.00641454
HAMP hepcidin antimicrobial peptide 0.00641055
ALDOC aldolase C, fructose-bisphosphate 0.00640428
SHCBP1 SHC SH2-domain binding protein 1 0.00639037
KLHL23 kelch-like family member 23 0.00635815
MTUS1 microtubule associated tumor suppressor 1 0.0063376
SH3BP4 SH3-domain binding protein 4 0.00629929
PLK1 polo-like kinase 1 0.00626519
ERG28 ergosterol biosynthesis 28 homolog 0.00624678
MYH11 myosin, heavy chain 11, smooth muscle 0.00623872
LUM lumican 0.00623833
PTH2R parathyroid hormone 2 receptor 0.00622734
HMGN5 high mobility group nucleosome binding domain 5 0.00622126
AEBP1 AE binding protein 1 0.00615889
IQGAP2 IQ motif containing GTPase activating protein 2 0.00615062
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00613341
NUSAP1 nucleolar and spindle associated protein 1 0.00606708
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00602788
DDHD2 DDHD domain containing 2 0.00601851
TFF1 trefoil factor 1 0.00599885
CERK ceramide kinase 0.00598758
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0059755
DEK DEK proto-oncogene 0.0059617
GCH1 GTP cyclohydrolase 1 0.00595166
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00591054
DSP desmoplakin 0.00590702
TARDBP TAR DNA binding protein 0.00590534
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00590071
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00587292
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00586525
ZBTB18 zinc finger and BTB domain containing 18 0.00584815
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00584371
VANGL1 VANGL planar cell polarity protein 1 0.00584156
TPI1 triosephosphate isomerase 1 0.00584076
LIG1 ligase I, DNA, ATP-dependent 0.00582902
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00582281
MLPH melanophilin 0.00581758
CDCA4 cell division cycle associated 4 0.00580429
SPC25 SPC25, NDC80 kinetochore complex component 0.00579531
RHOB ras homolog family member B 0.00578794
ACP6 acid phosphatase 6, lysophosphatidic 0.00577851
POGLUT2 protein O-glucosyltransferase 2 0.00575994
TACC3 transforming, acidic coiled-coil containing protein 3 0.00575024
TCEAL2 transcription elongation factor A (SII)-like 2 0.00574925
CENPF centromere protein F, 350/400kDa 0.00574479
KIF14 kinesin family member 14 0.00570909
CCNF cyclin F 0.00569671
WT1 Wilms tumor 1 0.00569214
ACD adrenocortical dysplasia homolog (mouse) 0.00568874
PCP4 Purkinje cell protein 4 0.00568744
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00568275
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00567786
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00567481
GOLGA8A golgin A8 family, member A 0.00565103
GREB1 growth regulation by estrogen in breast cancer 1 0.00564982
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00563712
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00562621
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00562613
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00561905
A2M alpha-2-macroglobulin 0.00561052
SULF1 sulfatase 1 0.00558625
NELFCD negative elongation factor complex member C/D 0.0055675
PRKD1 protein kinase D1 0.00555724
LRRC15 leucine rich repeat containing 15 0.00554982
YEATS4 YEATS domain containing 4 0.00554276
PSRC1 proline/serine-rich coiled-coil 1 0.00553708
ACOX2 acyl-CoA oxidase 2, branched chain 0.00552457
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00552352
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00551783
ITPKB inositol-trisphosphate 3-kinase B 0.0054932
HMG20B high mobility group 20B 0.00548729
ECI2 enoyl-CoA delta isomerase 2 0.00547484
HYOU1 hypoxia up-regulated 1 0.00547211
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00546907
HPCAL1 hippocalcin-like 1 0.0054679
N4BP2L2 NEDD4 binding protein 2-like 2 0.00543582
CRIP2 cysteine-rich protein 2 0.00541744
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.0054146
PMEL premelanosome protein 0.00540816
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00540484
MPHOSPH9 M-phase phosphoprotein 9 0.00540381
CADPS2 Ca++-dependent secretion activator 2 0.00539891
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00538431
KCTD3 potassium channel tetramerization domain containing 3 0.00537458
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.00536777
ESD esterase D 0.00535243
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0053493
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.005347
LONP2 lon peptidase 2, peroxisomal 0.0053442
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.00533888
MARCKSL1 MARCKS-like 1 0.00533692
CBR3 carbonyl reductase 3 0.00533552
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00532568
NSD2 nuclear receptor binding SET domain protein 2 0.0053239
CHD1L chromodomain helicase DNA binding protein 1-like 0.00532389
CCNA2 cyclin A2 0.00531871
GLB1 galactosidase, beta 1 0.00531257
OIP5 Opa interacting protein 5 0.00529806
ADGRF5 adhesion G protein-coupled receptor F5 0.00529668
VDAC3 voltage-dependent anion channel 3 0.00529553
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00528449
NVL nuclear VCP-like 0.00527673
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.00527048
TUBB2A tubulin, beta 2A class IIa 0.00526167
HMGB3 high mobility group box 3 0.00525292
FNBP1 formin binding protein 1 0.00525066
KRT18 keratin 18, type I 0.00522938
PLAT plasminogen activator, tissue 0.00522841
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.00522592
AOC3 amine oxidase, copper containing 3 0.0052223
GPC3 glypican 3 0.00521406
LAGE3 L antigen family, member 3 0.00521169
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00520927
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00520875
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.0051934
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00518552
F5 coagulation factor V (proaccelerin, labile factor) 0.00517792
CD99 CD99 molecule 0.00517301
PKN1 protein kinase N1 0.00516918
WFS1 Wolfram syndrome 1 (wolframin) 0.00516174
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.00515524
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00514121
SRSF6 serine/arginine-rich splicing factor 6 0.00512918
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00512252
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00511625
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.00511247
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.00510576
FANCL Fanconi anemia, complementation group L 0.00509432
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.00507436
PDZRN3 PDZ domain containing ring finger 3 0.0050694
PRUNE1 prune exopolyphosphatase 1 0.00504871
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.00504438
HPF1 histone PARylation factor 1 0.00502897
DCXR dicarbonyl/L-xylulose reductase 0.00502477
SEPTIN7 septin 7 0.00502001
PIMREG PICALM interacting mitotic regulator 0.00501308
PDGFRL platelet-derived growth factor receptor-like 0.00501067
PTBP1 polypyrimidine tract binding protein 1 0.00500393
MYH10 myosin, heavy chain 10, non-muscle 0.00500135
PRDX3 peroxiredoxin 3 0.00499391
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00499068
TRMT5 tRNA methyltransferase 5 0.00497559
HMGB1 high mobility group box 1 0.0049745
CD2 CD2 molecule 0.00496658
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 0.00494378
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.00494048
RNF130 ring finger protein 130 0.00493137
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00492352
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 0.00492339
NTS neurotensin 0.00491064
TNS1 tensin 1 0.00489793
MFAP2 microfibrillar-associated protein 2 0.00489584
AMDHD2 amidohydrolase domain containing 2 0.00489502
L1TD1 LINE-1 type transposase domain containing 1 0.00488153
PAH phenylalanine hydroxylase 0.00487641
PLAAT3 phospholipase A and acyltransferase 3 0.00486901
EPCAM epithelial cell adhesion molecule 0.00486847
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00486803
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.00485584
IL1RAP interleukin 1 receptor accessory protein 0.00485232
NAE1 NEDD8 activating enzyme E1 subunit 1 0.00485009
RAD51 RAD51 recombinase 0.00484278
SRSF7 serine/arginine-rich splicing factor 7 0.00482833
HOOK2 hook microtubule-tethering protein 2 0.00482811
NCKIPSD NCK interacting protein with SH3 domain 0.00482377
ACTN1 actinin, alpha 1 0.00482127
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.00482051
F8 coagulation factor VIII, procoagulant component 0.00481201
CBFB core-binding factor, beta subunit 0.00481113
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.00480904
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00480857
FBXO5 F-box protein 5 0.00479976
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.00479914
GLO1 glyoxalase I 0.00479805
NONO non-POU domain containing, octamer-binding 0.00479538
MAOB monoamine oxidase B 0.0047941
SFTPA2 surfactant protein A2 0.00479145
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00478652
ADGRE2 adhesion G protein-coupled receptor E2 0.00478132

decreased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 -0.0185579
CSTA cystatin A (stefin A) -0.0181786
S100A9 S100 calcium binding protein A9 -0.0163282
CA2 carbonic anhydrase II -0.015514
DEFB1 defensin, beta 1 -0.0152905
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0148606
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0144074
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0141765
SYNGR3 synaptogyrin 3 -0.01326
RND3 Rho family GTPase 3 -0.0129943
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0128725
ANXA1 annexin A1 -0.0128651
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0127924
KRT15 keratin 15, type I -0.0127059
STC2 stanniocalcin 2 -0.0124912
H1-2 H1.2 linker histone, cluster member -0.0120577
SLPI secretory leukocyte peptidase inhibitor -0.0117287
KRT5 keratin 5, type II -0.0117181
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0114123
KRT6A keratin 6A, type II -0.0113846
GJA1 gap junction protein, alpha 1, 43kDa -0.0113648
PERP PERP, TP53 apoptosis effector -0.0113204
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0112615
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0110759
CLCA4 chloride channel accessory 4 -0.0109797
RGCC regulator of cell cycle -0.010965
IPO13 importin 13 -0.0109517
PLBD1 phospholipase B domain containing 1 -0.0107616
AKR1C2 aldo-keto reductase family 1, member C2 -0.0106343
AKR1C1 aldo-keto reductase family 1, member C1 -0.0105166
KRT14 keratin 14, type I -0.0104365
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0102604
BTG1 B-cell translocation gene 1, anti-proliferative -0.010093
SGK1 serum/glucocorticoid regulated kinase 1 -0.0100713
NAMPT nicotinamide phosphoribosyltransferase -0.0100225
S100A8 S100 calcium binding protein A8 -0.00989667
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00985407
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00984307
HBD hemoglobin, delta -0.00984302
KRT6B keratin 6B, type II -0.00982927
HIST1H2AC histone cluster 1, H2ac -0.00978465
BASP1 brain abundant, membrane attached signal protein 1 -0.00978353
MT1X metallothionein 1X -0.00966741
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.0095966
TGFA transforming growth factor, alpha -0.00958451
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00953681
HIST1H2BD histone cluster 1, H2bd -0.00953213
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00945246
TACSTD2 tumor-associated calcium signal transducer 2 -0.00941675
NLRP2 NLR family, pyrin domain containing 2 -0.00940092
SPRR1B small proline-rich protein 1B -0.00934823
HMOX1 heme oxygenase 1 -0.00930642
CRYAB crystallin, alpha B -0.00930546
SCPEP1 serine carboxypeptidase 1 -0.00918639
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0091197
LTF lactotransferrin -0.00910869
NT5E 5'-nucleotidase, ecto (CD73) -0.00896533
FN1 fibronectin 1 -0.00894499
TFPI2 tissue factor pathway inhibitor 2 -0.00893257
MT1E metallothionein 1E -0.0089081
PDZK1IP1 PDZK1 interacting protein 1 -0.00887352
LITAF lipopolysaccharide-induced TNF factor -0.00885793
CNTN1 contactin 1 -0.00884716
TPD52L1 tumor protein D52-like 1 -0.00883649
TRIM29 tripartite motif containing 29 -0.00882455
PPL periplakin -0.00880861
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00875408
APOD apolipoprotein D -0.00870816
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00869079
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00864112
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00849908
HSPB8 heat shock 22kDa protein 8 -0.00849713
KLK11 kallikrein-related peptidase 11 -0.00843922
EMP1 epithelial membrane protein 1 -0.00841982
KRT13 keratin 13, type I -0.00838345
LY75 lymphocyte antigen 75 -0.00837988
RAB9A RAB9A, member RAS oncogene family -0.00823044
TP63 tumor protein p63 -0.008217
SCGB2A1 secretoglobin, family 2A, member 1 -0.00820411
HIST1H2BH histone cluster 1, H2bh -0.00818614
SIK1 salt-inducible kinase 1 -0.00814976
PTPRK protein tyrosine phosphatase, receptor type, K -0.00813281
ANXA2P2 annexin A2 pseudogene 2 -0.00812715
CRISP3 cysteine-rich secretory protein 3 -0.00812084
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00809791
AREG amphiregulin -0.00806616
GALC galactosylceramidase -0.00802685
G0S2 G0/G1 switch 2 -0.00799348
SCD5 stearoyl-CoA desaturase 5 -0.00796816
BLNK B-cell linker -0.00790405
NIBAN1 niban apoptosis regulator 1 -0.00787831
IFI27 interferon, alpha-inducible protein 27 -0.00784089
KRT17 keratin 17, type I -0.00782184
STOM stomatin -0.0078095
KRT23 keratin 23, type I -0.0077678
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00774543
DSG3 desmoglein 3 -0.00773954
ATF3 activating transcription factor 3 -0.00773608
IL1R1 interleukin 1 receptor, type I -0.00772499
MGLL monoglyceride lipase -0.00770814
IFRD1 interferon-related developmental regulator 1 -0.00769454
CA12 carbonic anhydrase XII -0.00767215
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00766615
CAV2 caveolin 2 -0.00754176
AKR1C3 aldo-keto reductase family 1, member C3 -0.00748337
GRB7 growth factor receptor-bound protein 7 -0.00744726
PLAU plasminogen activator, urokinase -0.00744669
DEPTOR DEP domain containing MTOR-interacting protein -0.00741204
MT1F metallothionein 1F -0.00736351
OPHN1 oligophrenin 1 -0.00734201
MAMLD1 mastermind-like domain containing 1 -0.00733773
NRIP3 nuclear receptor interacting protein 3 -0.00733174
BLVRB biliverdin reductase B -0.00731693
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00731429
TSPO translocator protein (18kDa) -0.00729533
FTH1 ferritin, heavy polypeptide 1 -0.00728461
STK17A serine/threonine kinase 17a -0.00724801
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00723675
MIR22HG MIR22 host gene -0.00723572
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00722566
CLDN1 claudin 1 -0.00721854
CLTB clathrin, light chain B -0.00720798
STC1 stanniocalcin 1 -0.00714558
IFNGR1 interferon gamma receptor 1 -0.00710604
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00710114
HSPA1A heat shock 70kDa protein 1A -0.00708494
TUBA4A tubulin, alpha 4a -0.00707727
FAM171A1 family with sequence similarity 171, member A1 -0.00707176
ELANE elastase, neutrophil expressed -0.00706114
KLK10 kallikrein-related peptidase 10 -0.00704663
ARMCX3 armadillo repeat containing, X-linked 3 -0.00704114
PI3 peptidase inhibitor 3, skin-derived -0.00701313
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -0.00698724
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00696322
KYNU kynureninase -0.00695833
CLU clusterin -0.00693624
BICC1 BicC family RNA binding protein 1 -0.00692875
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00692591
GOLT1B golgi transport 1B -0.00691246
SPRR1A small proline-rich protein 1A -0.00690798
FADS3 fatty acid desaturase 3 -0.00689491
OLFM4 olfactomedin 4 -0.00688975
CTSD cathepsin D -0.00686979
DDIT3 DNA-damage-inducible transcript 3 -0.00683471
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00679571
IL18 interleukin 18 -0.00679406
PIGR polymeric immunoglobulin receptor -0.00676892
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00676562
CD58 CD58 molecule -0.00676448
KLF5 Kruppel-like factor 5 (intestinal) -0.00676358
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00676205
OLFML2A olfactomedin-like 2A -0.00675984
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00674552
PTK2B protein tyrosine kinase 2 beta -0.00672567
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00671591
MCL1 myeloid cell leukemia 1 -0.00669037
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00667422
MT1M metallothionein 1M -0.00666803
IFT57 intraflagellar transport 57 -0.00664496
EIF5 eukaryotic translation initiation factor 5 -0.00664174
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00664161
CTSG cathepsin G -0.00663562
KLF4 Kruppel-like factor 4 (gut) -0.00661906
ANXA2 annexin A2 -0.00661655
HIST1H2BK histone cluster 1, H2bk -0.00660404
ZC3H12A zinc finger CCCH-type containing 12A -0.00659105
AOC1 amine oxidase, copper containing 1 -0.00659031
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00658912
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00658082
MALL mal, T-cell differentiation protein-like -0.00656244
MMP9 matrix metallopeptidase 9 -0.00656046
CCNG2 cyclin G2 -0.006556
JUP junction plakoglobin -0.00655554
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00655393
ADM adrenomedullin -0.00654169
CDC42 cell division cycle 42 -0.00651333
IER5 immediate early response 5 -0.00650903
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00650892
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00650008
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -0.00647665
SFRP1 secreted frizzled-related protein 1 -0.00646085
DEFA4 defensin, alpha 4, corticostatin -0.00645589
CYBA cytochrome b-245, alpha polypeptide -0.00645248
KRT16 keratin 16, type I -0.00642595
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00642458
AHNAK AHNAK nucleoprotein -0.00641148
CD38 CD38 molecule -0.00640708
CLCA2 chloride channel accessory 2 -0.00639251
MYOF myoferlin -0.00635019
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00632814
LPAR1 lysophosphatidic acid receptor 1 -0.00632644
NEU1 sialidase 1 (lysosomal sialidase) -0.00631238
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00631205
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00630478
ANXA4 annexin A4 -0.00629494
C1S complement component 1, s subcomponent -0.00628598
TRIP6 thyroid hormone receptor interactor 6 -0.00628482
INAVA innate immunity activator -0.00627005
FGFBP1 fibroblast growth factor binding protein 1 -0.00624352
BIRC3 baculoviral IAP repeat containing 3 -0.00617901
TPBG trophoblast glycoprotein -0.00615255
ADAM10 ADAM metallopeptidase domain 10 -0.00613991
VAMP8 vesicle-associated membrane protein 8 -0.00613831
SOD2 superoxide dismutase 2, mitochondrial -0.00613612
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00609439
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -0.00609266
MSMB microseminoprotein, beta- -0.00609039
BPGM 2,3-bisphosphoglycerate mutase -0.00607705
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00607401
HTRA1 HtrA serine peptidase 1 -0.00607223
PTHLH parathyroid hormone-like hormone -0.00606907
LARP6 La ribonucleoprotein domain family, member 6 -0.00606383
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00606188
TMEM59 transmembrane protein 59 -0.00605872
S100A7 S100 calcium binding protein A7 -0.00605367
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00605333
CTSC cathepsin C -0.00604509
OGFRL1 opioid growth factor receptor-like 1 -0.00604174
WEE1 WEE1 G2 checkpoint kinase -0.00604076
SOCS1 suppressor of cytokine signaling 1 -0.00603997
PDZD8 PDZ domain containing 8 -0.0060342
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.00602197
AIM2 absent in melanoma 2 -0.00600444
BPI bactericidal/permeability-increasing protein -0.00599799
BCL3 B-cell CLL/lymphoma 3 -0.0059969
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00599601
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00598777
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00598106
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00597871
PITX3 paired-like homeodomain 3 -0.00596031
CD19 CD19 molecule -0.00594565
GSDMB gasdermin B -0.00594228
FCGBP Fc fragment of IgG binding protein -0.00593308
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00589755
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00588965
C3 complement component 3 -0.00588756
TSPAN1 tetraspanin 1 -0.00588212
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00587929
YPEL5 yippee-like 5 (Drosophila) -0.00587544
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00587184
MICB MHC class I polypeptide-related sequence B -0.00587069
IRF1 interferon regulatory factor 1 -0.00586054
GEM GTP binding protein overexpressed in skeletal muscle -0.00585024
EDN3 endothelin 3 -0.00584179
DUSP5 dual specificity phosphatase 5 -0.00582642
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00581879
PPIF peptidylprolyl isomerase F -0.00581089