| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/24763624 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in S107 relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C15ORF61 | chromosome 15 open reading frame 61 | 0.56 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.54 |
| CCN3 | cellular communication network factor 3 | 0.52 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.48 |
| GGT7 | gamma-glutamyltransferase 7 | 0.46 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.45 |
| ANGPTL4 | angiopoietin-like 4 | 0.41 |
| ANKRD20A4 | ankyrin repeat domain 20 family, member A4 | 0.4 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.38 |
| NAV2 | neuron navigator 2 | 0.38 |
| PLA2G12A | phospholipase A2, group XIIA | 0.38 |
| TRAPPC5 | trafficking protein particle complex 5 | 0.37 |
| MSLN | mesothelin | 0.37 |
| ST5 | suppression of tumorigenicity 5 | 0.37 |
| BORCS5 | BLOC-1 related complex subunit 5 | 0.36 |
| MRAS | muscle RAS oncogene homolog | 0.36 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.34 |
| TMEM175 | transmembrane protein 175 | 0.34 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.33 |
| MIER3 | mesoderm induction early response 1, family member 3 | 0.33 |
| RELT | RELT tumor necrosis factor receptor | 0.32 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.32 |
| DENND4B | DENN/MADD domain containing 4B | 0.32 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | 0.32 |
| CNTROB | centrobin, centrosomal BRCA2 interacting protein | 0.31 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.31 |
| VRK1 | vaccinia related kinase 1 | 0.31 |
| FBXW5 | F-box and WD repeat domain containing 5 | 0.31 |
| PITX1 | paired-like homeodomain 1 | 0.3 |
| COQ4 | coenzyme Q4 | 0.3 |
| GIN1 | gypsy retrotransposon integrase 1 | 0.3 |
| SET | SET nuclear proto-oncogene | 0.29 |
| PARPBP | PARP1 binding protein | 0.29 |
| MED10 | mediator complex subunit 10 | 0.29 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.29 |
| CHSY3 | chondroitin sulfate synthase 3 | 0.29 |
| VMP1 | vacuole membrane protein 1 | 0.28 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 0.28 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.28 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 | 0.27 |
| ZFPM1 | zinc finger protein, FOG family member 1 | 0.27 |
| AUNIP | aurora kinase A and ninein interacting protein | 0.27 |
| ATG4A | autophagy related 4A, cysteine peptidase | 0.27 |
| SMAD1 | SMAD family member 1 | 0.27 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.27 |
| ZNF658 | zinc finger protein 658 | 0.27 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.27 |
| FAM110C | family with sequence similarity 110, member C | 0.26 |
| ZBTB3 | zinc finger and BTB domain containing 3 | 0.26 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.26 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.26 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.25 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.25 |
| NHEJ1 | nonhomologous end-joining factor 1 | 0.25 |
| BRCA2 | breast cancer 2, early onset | 0.25 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.25 |
| SYNE4 | spectrin repeat containing, nuclear envelope family member 4 | 0.25 |
| NKD2 | naked cuticle homolog 2 (Drosophila) | 0.25 |
| RNF187 | ring finger protein 187 | 0.25 |
| KLHL21 | kelch-like family member 21 | 0.25 |
| TEDC2 | tubulin epsilon and delta complex 2 | 0.24 |
| GJB3 | gap junction protein, beta 3, 31kDa | 0.24 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.24 |
| ZNF799 | zinc finger protein 799 | 0.24 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.24 |
| RPUSD1 | RNA pseudouridylate synthase domain containing 1 | 0.23 |
| CCPG1 | cell cycle progression 1 | 0.23 |
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 | 0.23 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.23 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | 0.23 |
| PRKCH | protein kinase C, eta | 0.23 |
| ZNF451 | zinc finger protein 451 | 0.23 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.22 |
| HPS1 | Hermansky-Pudlak syndrome 1 | 0.22 |
| THBS2 | thrombospondin 2 | 0.22 |
| ZNF175 | zinc finger protein 175 | 0.22 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 0.22 |
| FNIP1 | folliculin interacting protein 1 | 0.22 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.22 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.22 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | 0.22 |
| PRSS23 | protease, serine, 23 | 0.22 |
| SPIN2B | spindlin family, member 2B | 0.22 |
| CFD | complement factor D (adipsin) | 0.21 |
| ZNF707 | zinc finger protein 707 | 0.21 |
| KDF1 | keratinocyte differentiation factor 1 | 0.21 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.21 |
| COMMD9 | COMM domain containing 9 | 0.21 |
| RAB30 | RAB30, member RAS oncogene family | 0.21 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.21 |
| MRPL50 | mitochondrial ribosomal protein L50 | 0.21 |
| CDX2 | caudal type homeobox 2 | 0.21 |
| DCLRE1A | DNA cross-link repair 1A | 0.21 |
| SNX15 | sorting nexin 15 | 0.21 |
| LRR1 | leucine rich repeat protein 1 | 0.21 |
| PKHD1 | polycystic kidney and hepatic disease 1 (autosomal recessive) | 0.21 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.2 |
| DUSP5 | dual specificity phosphatase 5 | 0.2 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.2 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 | -1.04 |
| POF1B | premature ovarian failure, 1B | -0.83 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.83 |
| RNF145 | ring finger protein 145 | -0.73 |
| CCDC90B | coiled-coil domain containing 90B | -0.66 |
| ZG16B | zymogen granule protein 16B | -0.66 |
| TIGD2 | tigger transposable element derived 2 | -0.6 |
| ATE1 | arginyltransferase 1 | -0.55 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | -0.55 |
| PKNOX1 | PBX/knotted 1 homeobox 1 | -0.52 |
| SYT7 | synaptotagmin VII | -0.5 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -0.49 |
| TMEM64 | transmembrane protein 64 | -0.49 |
| ZNF516 | zinc finger protein 516 | -0.48 |
| ANKRD10 | ankyrin repeat domain 10 | -0.47 |
| PLXNB1 | plexin B1 | -0.46 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.45 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.45 |
| GMCL2 | germ cell-less 2, spermatogenesis associated | -0.45 |
| GLRX | glutaredoxin (thioltransferase) | -0.43 |
| PRDM16 | PR domain containing 16 | -0.42 |
| ZNF623 | zinc finger protein 623 | -0.42 |
| PARD6A | par-6 family cell polarity regulator alpha | -0.42 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.41 |
| RPGR | retinitis pigmentosa GTPase regulator | -0.41 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.4 |
| SYNPO | synaptopodin | -0.4 |
| KLHL17 | kelch-like family member 17 | -0.39 |
| MYBPC1 | myosin binding protein C, slow type | -0.39 |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 | -0.39 |
| RPE | ribulose-5-phosphate-3-epimerase | -0.39 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.38 |
| NEU3 | sialidase 3 (membrane sialidase) | -0.38 |
| NHLRC3 | NHL repeat containing 3 | -0.37 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.36 |
| ONECUT3 | one cut homeobox 3 | -0.35 |
| GATA6 | GATA binding protein 6 | -0.35 |
| CASZ1 | castor zinc finger 1 | -0.35 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 | -0.35 |
| MFSD6 | major facilitator superfamily domain containing 6 | -0.35 |
| CCDC102A | coiled-coil domain containing 102A | -0.34 |
| CILP2 | cartilage intermediate layer protein 2 | -0.34 |
| SNAP91 | synaptosomal-associated protein, 91kDa | -0.34 |
| ZDHHC2 | zinc finger, DHHC-type containing 2 | -0.33 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit | -0.33 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.33 |
| PIP | prolactin-induced protein | -0.32 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.32 |
| TMEM179B | transmembrane protein 179B | -0.31 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | -0.31 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.31 |
| C7ORF25 | chromosome 7 open reading frame 25 | -0.3 |
| SNX29 | sorting nexin 29 | -0.3 |
| GATA2 | GATA binding protein 2 | -0.3 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.3 |
| OSBPL7 | oxysterol binding protein-like 7 | -0.3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | -0.3 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.3 |
| ARG2 | arginase 2 | -0.3 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | -0.3 |
| FAM102A | family with sequence similarity 102, member A | -0.29 |
| IQCE | IQ motif containing E | -0.29 |
| DNAH6 | dynein, axonemal, heavy chain 6 | -0.29 |
| CENPT | centromere protein T | -0.28 |
| MIDN | midnolin | -0.28 |
| KSR2 | kinase suppressor of ras 2 | -0.28 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | -0.28 |
| TTC9 | tetratricopeptide repeat domain 9 | -0.28 |
| DNAH1 | dynein, axonemal, heavy chain 1 | -0.27 |
| CCNY | cyclin Y | -0.27 |
| OBSL1 | obscurin-like 1 | -0.27 |
| ZNF444 | zinc finger protein 444 | -0.27 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.27 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.27 |
| TAPT1 | transmembrane anterior posterior transformation 1 | -0.26 |
| NAXD | NAD(P)HX dehydratase | -0.26 |
| IFT22 | intraflagellar transport 22 | -0.26 |
| FZD7 | frizzled class receptor 7 | -0.26 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.25 |
| LAMA3 | laminin, alpha 3 | -0.25 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.25 |
| CRAT | carnitine O-acetyltransferase | -0.25 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.25 |
| PUDP | pseudouridine 5'-phosphatase | -0.25 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.25 |
| CCNQ | cyclin Q | -0.25 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.25 |
| MDP1 | magnesium-dependent phosphatase 1 | -0.25 |
| NDFIP2 | Nedd4 family interacting protein 2 | -0.25 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.25 |
| PRKD3 | protein kinase D3 | -0.25 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.25 |
| BRK1 | BRICK1, SCAR/WAVE actin-nucleating complex subunit | -0.24 |
| NCKAP5L | NCK-associated protein 5-like | -0.24 |
| ING4 | inhibitor of growth family, member 4 | -0.24 |
| MMGT1 | membrane magnesium transporter 1 | -0.24 |
| LRRC8B | leucine rich repeat containing 8 family, member B | -0.24 |
| ATXN7L3B | ataxin 7-like 3B | -0.24 |
| GUK1 | guanylate kinase 1 | -0.24 |
| FMNL1 | formin-like 1 | -0.24 |
