| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | serum amyloid A1|This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012] (NCBI Entrez Gene Database, 6288) |
| External Link | https://ncbi.nlm.nih.gov/gene/6288 |
| Similar Terms | |
| Downloads & Tools |
474 genes differentially expressed following the SAA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100P | S100 calcium binding protein P | 0.0198769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0193347 |
| KRT14 | keratin 14, type I | 0.0188597 |
| MX1 | MX dynamin-like GTPase 1 | 0.0182441 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0180155 |
| KRT7 | keratin 7, type II | 0.0167116 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0165771 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0163652 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0154776 |
| CCN2 | cellular communication network factor 2 | 0.0154659 |
| RGCC | regulator of cell cycle | 0.0154404 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0150748 |
| PERP | PERP, TP53 apoptosis effector | 0.0150086 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0149092 |
| KRT17 | keratin 17, type I | 0.0148595 |
| GNAS | GNAS complex locus | 0.0139565 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0138019 |
| G0S2 | G0/G1 switch 2 | 0.0137782 |
| ANXA1 | annexin A1 | 0.013675 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0135602 |
| IFI44L | interferon-induced protein 44-like | 0.0134652 |
| TRIM29 | tripartite motif containing 29 | 0.013267 |
| XIC | X chromosome inactivation center | 0.0131912 |
| NEBL | nebulette | 0.0131488 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.0131023 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.0130053 |
| IPO13 | importin 13 | 0.0127878 |
| IFI44 | interferon-induced protein 44 | 0.0123365 |
| FN1 | fibronectin 1 | 0.0117811 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.011761 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0116863 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0116142 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0114943 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0114931 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0113004 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.011041 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0110177 |
| ANXA3 | annexin A3 | 0.0109166 |
| LCN2 | lipocalin 2 | 0.0107901 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.0107473 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.0107148 |
| INHBA | inhibin, beta A | 0.0106156 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0106146 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0104954 |
| CCNA2 | cyclin A2 | 0.0104145 |
| ECM1 | extracellular matrix protein 1 | 0.0102815 |
| KRT23 | keratin 23, type I | 0.0102759 |
| S100A11 | S100 calcium binding protein A11 | 0.0102038 |
| INHBB | inhibin, beta B | 0.0101717 |
| MT1F | metallothionein 1F | 0.01011 |
| CRYAB | crystallin, alpha B | 0.010008 |
| KLK10 | kallikrein-related peptidase 10 | 0.00995862 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00991955 |
| MT1E | metallothionein 1E | 0.00985745 |
| LAMC2 | laminin, gamma 2 | 0.00984827 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00984686 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00984508 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00979986 |
| APOD | apolipoprotein D | 0.00979611 |
| GLOD4 | glyoxalase domain containing 4 | 0.00973977 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00967808 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00967526 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00962175 |
| IL1RN | interleukin 1 receptor antagonist | 0.00961857 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00956466 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00950153 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0094561 |
| MT1G | metallothionein 1G | 0.00941813 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00940448 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00939141 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.0093687 |
| MT1H | metallothionein 1H | 0.00936347 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00932625 |
| LTF | lactotransferrin | 0.00932363 |
| KRT5 | keratin 5, type II | 0.00928465 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00922573 |
| INAVA | innate immunity activator | 0.00920355 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00919903 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00919848 |
| IRS1 | insulin receptor substrate 1 | 0.00919318 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00918652 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00917579 |
| RRAGD | Ras-related GTP binding D | 0.00917578 |
| MAP7 | microtubule-associated protein 7 | 0.00910332 |
| AMOTL2 | angiomotin like 2 | 0.00897974 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00894861 |
| KRT16 | keratin 16, type I | 0.00894806 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00888902 |
| PXDC1 | PX domain containing 1 | 0.00880522 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00880174 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00875892 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00875524 |
| MIR22HG | MIR22 host gene | 0.00871639 |
| CYTL1 | cytokine-like 1 | 0.00860047 |
| JAG1 | jagged 1 | 0.00858449 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00854215 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00852237 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00851448 |
| EFNA1 | ephrin-A1 | 0.00850519 |
| MT1X | metallothionein 1X | 0.00845927 |
| SPRR1B | small proline-rich protein 1B | 0.0083985 |
| VEGFA | vascular endothelial growth factor A | 0.00834361 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00832548 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00832492 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00832206 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00831449 |
| ABAT | 4-aminobutyrate aminotransferase | 0.0082976 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00829198 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00826081 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.0082462 |
| SPRR3 | small proline-rich protein 3 | 0.00821195 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00817837 |
| S100A8 | S100 calcium binding protein A8 | 0.0081711 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00815111 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00815074 |
| IRF7 | interferon regulatory factor 7 | 0.00813788 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00811418 |
| PLK2 | polo-like kinase 2 | 0.00809419 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00805073 |
| EPS8L2 | EPS8-like 2 | 0.00799569 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00796544 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00796399 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00795943 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00793666 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00791805 |
| LAMB3 | laminin, beta 3 | 0.00790664 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00790025 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00785843 |
| PEG10 | paternally expressed 10 | 0.00785112 |
| KRT6A | keratin 6A, type II | 0.0078506 |
| MMP7 | matrix metallopeptidase 7 | 0.00785039 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00782519 |
| ADIRF | adipogenesis regulatory factor | 0.00780055 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00779807 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0077908 |
| CDA | cytidine deaminase | 0.00778444 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00777625 |
| KRT6B | keratin 6B, type II | 0.00777596 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0077572 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00773717 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00772339 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0076765 |
| OPHN1 | oligophrenin 1 | 0.00767451 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00766796 |
| S100A9 | S100 calcium binding protein A9 | 0.00764193 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00762309 |
| CSTA | cystatin A (stefin A) | 0.00757196 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00756648 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00756618 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00755189 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0075459 |
| HMOX1 | heme oxygenase 1 | 0.00754329 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00754274 |
| DSG3 | desmoglein 3 | 0.00753835 |
| RND3 | Rho family GTPase 3 | 0.00753301 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.00751632 |
| MAP7D1 | MAP7 domain containing 1 | 0.00746247 |
| MSLN | mesothelin | 0.00746147 |
| CST1 | cystatin SN | 0.00745477 |
| LIPG | lipase, endothelial | 0.00745231 |
| ESR1 | estrogen receptor 1 | 0.00744658 |
| SSR4 | signal sequence receptor, delta | 0.00742758 |
| GRN | granulin | 0.00740779 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00739959 |
| ABLIM1 | actin binding LIM protein 1 | 0.00738014 |
| PLLP | plasmolipin | 0.00736567 |
| EMP1 | epithelial membrane protein 1 | 0.00733849 |
| TMEM100 | transmembrane protein 100 | 0.00726753 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00726575 |
| ADAM8 | ADAM metallopeptidase domain 8 | 0.0072363 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00722032 |
| TUFT1 | tuftelin 1 | 0.00721142 |
| MSX1 | msh homeobox 1 | 0.0072093 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00720597 |
| AREG | amphiregulin | 0.00717058 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00716548 |
| TSPO | translocator protein (18kDa) | 0.00715489 |
| KRT15 | keratin 15, type I | 0.00715113 |
| CUEDC1 | CUE domain containing 1 | 0.00715053 |
| FAM107A | family with sequence similarity 107, member A | 0.00713053 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00710739 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00709045 |
| WWC1 | WW and C2 domain containing 1 | 0.00707613 |
| DYSF | dysferlin | 0.00706045 |
| KRT81 | keratin 81, type II | 0.00704174 |
| THBS4 | thrombospondin 4 | 0.00702993 |
| STK26 | serine/threonine protein kinase 26 | 0.00700556 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00699226 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00698465 |
| COL5A2 | collagen, type V, alpha 2 | 0.00696451 |
| TGFA | transforming growth factor, alpha | 0.00696312 |
| MT1M | metallothionein 1M | 0.00696279 |
| HIP1R | huntingtin interacting protein 1 related | 0.00694577 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00694546 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.0069318 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00690632 |
| MXRA7 | matrix-remodelling associated 7 | 0.00689774 |
| SIRPA | signal-regulatory protein alpha | 0.00688404 |
| EPCAM | epithelial cell adhesion molecule | 0.0068696 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00686689 |
| STC2 | stanniocalcin 2 | 0.00685421 |
| MYOF | myoferlin | 0.00682407 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00682351 |
| CES1 | carboxylesterase 1 | 0.0067602 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00673192 |
| SP100 | SP100 nuclear antigen | 0.00672865 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00672354 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00669398 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00668849 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0066729 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.00663436 |
| CAV2 | caveolin 2 | 0.00661552 |
| MT2A | metallothionein 2A | 0.00657889 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00656412 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00654288 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00653613 |
| TAGLN | transgelin | 0.00652624 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00651886 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00651142 |
| SPRR1A | small proline-rich protein 1A | 0.00650335 |
| IRS2 | insulin receptor substrate 2 | 0.00649975 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0064852 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00648232 |
| S100A12 | S100 calcium binding protein A12 | 0.00647038 |
| EDN3 | endothelin 3 | 0.00646619 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00646496 |
| COBL | cordon-bleu WH2 repeat protein | 0.00646333 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00644874 |
| S100A2 | S100 calcium binding protein A2 | 0.00643747 |
| S100A10 | S100 calcium binding protein A10 | 0.00642053 |
| BGN | biglycan | 0.00638156 |
| IER5 | immediate early response 5 | 0.00636221 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00634919 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.0063165 |
| CPM | carboxypeptidase M | 0.00629443 |
| MYO1B | myosin IB | 0.00629416 |
| RNASET2 | ribonuclease T2 | 0.00627091 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0062594 |
| A2M | alpha-2-macroglobulin | 0.00622519 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00622452 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00622318 |
| RRAGC | Ras-related GTP binding C | 0.00620656 |
| BAG3 | BCL2-associated athanogene 3 | 0.00620147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHEK2 | checkpoint kinase 2 | -0.0180135 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0163204 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0137695 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.0134479 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0131959 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.0121266 |
| PTK2 | protein tyrosine kinase 2 | -0.0119998 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0118568 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.0111759 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0111066 |
| LAMA4 | laminin, alpha 4 | -0.0110988 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0110253 |
| CLCA1 | chloride channel accessory 1 | -0.0108422 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0101986 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0100985 |
| KIF20A | kinesin family member 20A | -0.00983031 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00971802 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.0096589 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00960038 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00936929 |
| FABP1 | fatty acid binding protein 1, liver | -0.0091469 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00897537 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00891505 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00871048 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00862146 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00859774 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00856618 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00854879 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00844403 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00843667 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00841233 |
| BCHE | butyrylcholinesterase | -0.0083356 |
| CNN3 | calponin 3, acidic | -0.00831617 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00829689 |
| PLS3 | plastin 3 | -0.00829673 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00828581 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00826076 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00822861 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00813931 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00799959 |
| MEIS2 | Meis homeobox 2 | -0.00795354 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00794352 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00791728 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00789986 |
| SELENBP1 | selenium binding protein 1 | -0.00776325 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00773438 |
| LOX | lysyl oxidase | -0.00771199 |
| THBS1 | thrombospondin 1 | -0.00769453 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -0.0076862 |
| CFH | complement factor H | -0.00768508 |
| PRDX2 | peroxiredoxin 2 | -0.00766359 |
| LMNB1 | lamin B1 | -0.00765731 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00762789 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.007619 |
| MRPS2 | mitochondrial ribosomal protein S2 | -0.0075163 |
| GANAB | glucosidase, alpha; neutral AB | -0.00744371 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00743456 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00743396 |
| ANO10 | anoctamin 10 | -0.00741761 |
| HOXB6 | homeobox B6 | -0.00740204 |
| XK | X-linked Kx blood group | -0.00740017 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00736982 |
| FCGBP | Fc fragment of IgG binding protein | -0.0073477 |
| BNC2 | basonuclin 2 | -0.0073136 |
| ZG16 | zymogen granule protein 16 | -0.00729291 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00728528 |
| RANBP1 | RAN binding protein 1 | -0.00727943 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00726233 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.00725406 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00724393 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0072359 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -0.00723205 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00723035 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00719118 |
| ASPH | aspartate beta-hydroxylase | -0.00718988 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00714974 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00714415 |
| CHP2 | calcineurin-like EF-hand protein 2 | -0.00713379 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00712095 |
| REG3A | regenerating islet-derived 3 alpha | -0.00709987 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00703323 |
| NID1 | nidogen 1 | -0.00702945 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0069936 |
| SST | somatostatin | -0.0069746 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00691917 |
| PIR | pirin (iron-binding nuclear protein) | -0.0069111 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00689473 |
| OIP5 | Opa interacting protein 5 | -0.00686317 |
| PLTP | phospholipid transfer protein | -0.00685415 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00685313 |
| RCAN1 | regulator of calcineurin 1 | -0.00684882 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00684274 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00683278 |
| PLXNC1 | plexin C1 | -0.00683184 |
| FOXF1 | forkhead box F1 | -0.00682498 |
| INSIG1 | insulin induced gene 1 | -0.00681633 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.006802 |
| TRMT5 | tRNA methyltransferase 5 | -0.00677719 |
| TMEM14B | transmembrane protein 14B | -0.00675606 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.00672895 |
| STMN2 | stathmin 2 | -0.00671806 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00670377 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00670315 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00670103 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00669664 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00669538 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.00667792 |
| TOX3 | TOX high mobility group box family member 3 | -0.0066571 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00664316 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0066404 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00660223 |
| ERLIN2 | ER lipid raft associated 2 | -0.00659487 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00659085 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00657232 |
| C1R | complement component 1, r subcomponent | -0.00656522 |
| FBXO5 | F-box protein 5 | -0.00656371 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00655504 |
| OLFM1 | olfactomedin 1 | -0.00654992 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00654452 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00651128 |
| NTS | neurotensin | -0.00649356 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00649106 |
| DIPK1A | divergent protein kinase domain 1A | -0.0064804 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.0064737 |
| IL7 | interleukin 7 | -0.00645667 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00645275 |
| NRN1 | neuritin 1 | -0.00641774 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00641486 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.006407 |
| SNX11 | sorting nexin 11 | -0.00640614 |
| CCNB2 | cyclin B2 | -0.00639786 |
| GRAMD4 | GRAM domain containing 4 | -0.00638251 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00637212 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00636165 |
| TYRP1 | tyrosinase-related protein 1 | -0.00635496 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00634686 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | -0.00634047 |
| RAI14 | retinoic acid induced 14 | -0.00633373 |
| RPA3 | replication protein A3, 14kDa | -0.00631924 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00631686 |
| TOX | thymocyte selection-associated high mobility group box | -0.00631481 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0063097 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.00630536 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00630461 |
| PMP22 | peripheral myelin protein 22 | -0.00629901 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.0062904 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00628907 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00628054 |
| TMEM106C | transmembrane protein 106C | -0.00625578 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | -0.00624737 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00624105 |
| TMOD1 | tropomodulin 1 | -0.00622543 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00622022 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00620614 |
| MMP12 | matrix metallopeptidase 12 | -0.00620308 |
| GPM6B | glycoprotein M6B | -0.00618975 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00618806 |
| RHOA | ras homolog family member A | -0.00617118 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00616055 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00611775 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00610586 |
| HDAC1 | histone deacetylase 1 | -0.00610487 |
| REG1A | regenerating islet-derived 1 alpha | -0.00610109 |
| PGC | progastricsin (pepsinogen C) | -0.00609515 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00605587 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00604791 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -0.00603943 |
| PRKCB | protein kinase C, beta | -0.00603531 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00602428 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00602168 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00601371 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00600853 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00599463 |
| MOCOS | molybdenum cofactor sulfurase | -0.00598111 |
| ANO3 | anoctamin 3 | -0.00597656 |
| EREG | epiregulin | -0.00595268 |
| DENND1A | DENN/MADD domain containing 1A | -0.00594367 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00593985 |
| RPS5 | ribosomal protein S5 | -0.00593319 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00593174 |
| TMX1 | thioredoxin-related transmembrane protein 1 | -0.00591418 |
| AK4 | adenylate kinase 4 | -0.00591188 |
| MMP9 | matrix metallopeptidase 9 | -0.00589961 |
| PARPBP | PARP1 binding protein | -0.00589616 |
| TXNIP | thioredoxin interacting protein | -0.00589287 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.00588967 |
| RTN1 | reticulon 1 | -0.00587959 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00587786 |
| WT1 | Wilms tumor 1 | -0.00585438 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00583748 |
| FAM3C | family with sequence similarity 3, member C | -0.00583733 |
| RCAN2 | regulator of calcineurin 2 | -0.00582923 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00581804 |
| CENPM | centromere protein M | -0.00581719 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0058168 |
| KIAA0930 | KIAA0930 | -0.00580432 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00576716 |
| DST | dystonin | -0.00576438 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00575989 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00573808 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00573752 |
| EXTL2 | exostosin-like glycosyltransferase 2 | -0.00573203 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00573086 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.00573041 |
| APOC2 | apolipoprotein C-II | -0.00572968 |
| NES | nestin | -0.00572737 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00572174 |
| FGL2 | fibrinogen-like 2 | -0.00571964 |
| HOXA5 | homeobox A5 | -0.00569987 |
| HTRA1 | HtrA serine peptidase 1 | -0.00568878 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00568026 |
| ISL1 | ISL LIM homeobox 1 | -0.00566631 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.00565993 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00565533 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00564698 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00563504 |
| SRGN | serglycin | -0.00562941 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0056196 |
| ENO1 | enolase 1, (alpha) | -0.00561894 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.00561432 |
| RNF130 | ring finger protein 130 | -0.00560936 |
| NVL | nuclear VCP-like | -0.00560066 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.0055965 |
| GCG | glucagon | -0.00559389 |
| ADM | adrenomedullin | -0.00559361 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00558951 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00558476 |
| ADORA2B | adenosine A2b receptor | -0.00557742 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00557695 |
| B3GNT1 | -0.00557649 | |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00557637 |