SAE1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description SUMO1 activating enzyme subunit 1|Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] (NCBI Entrez Gene Database, 10055)
External Link http://www.ncbi.nlm.nih.gov/gene/10055
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Genes

108 interacting proteins for SAE1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ADSL adenylosuccinate lyase
APP amyloid beta (A4) precursor protein
ARHGAP35 Rho GTPase activating protein 35
ARID1A AT rich interactive domain 1A (SWI-like)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF7 activating transcription factor 7
BAG3 BCL2-associated athanogene 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALU calumenin
CSMD1 CUB and Sushi multiple domains 1
CUL5 cullin 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHPS deoxyhypusine synthase
DNAH9 dynein, axonemal, heavy chain 9
DPP9 dipeptidyl-peptidase 9
DROSHA drosha, ribonuclease type III
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
EBF1 early B-cell factor 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELF1 E74-like factor 1 (ets domain transcription factor)
EPHB6 EPH receptor B6
ERCC5 excision repair cross-complementation group 5
ETV4 ets variant 4
FKBP4 FK506 binding protein 4, 59kDa
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HNF1A HNF1 homeobox A
HSF4 heat shock transcription factor 4
HSPA1B heat shock 70kDa protein 1B
HSPA2 heat shock 70kDa protein 2
IDI2 isopentenyl-diphosphate delta isomerase 2
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL3RA interleukin 3 receptor, alpha (low affinity)
KDM2A lysine (K)-specific demethylase 2A
KIF13B kinesin family member 13B
KMT2B lysine (K)-specific methyltransferase 2B
LPAR2 lysophosphatidic acid receptor 2
LPAR4 lysophosphatidic acid receptor 4
LPP LIM domain containing preferred translocation partner in lipoma
LSM1 LSM1, U6 small nuclear RNA associated
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAX MYC associated factor X
MCM3 minichromosome maintenance complex component 3
MED23 mediator complex subunit 23
MTMR6 myotubularin related protein 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR2 nuclear receptor corepressor 2
NKRF NFKB repressing factor
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OLA1 Obg-like ATPase 1
OSBPL1A oxysterol binding protein-like 1A
OSGEP O-sialoglycoprotein endopeptidase
PANK4 pantothenate kinase 4
PANX3 pannexin 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDH9 protocadherin 9
PDE12 phosphodiesterase 12
POU2F3 POU class 2 homeobox 3
PPAP2B phosphatidic acid phosphatase type 2B
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTK2 protein tyrosine kinase 2
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SENP7 SUMO1/sentrin specific peptidase 7
SIN3A SIN3 transcription regulator family member A
SMO smoothened, frizzled class receptor
SP100 SP100 nuclear antigen
SPEN spen family transcriptional repressor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TP53RK TP53 regulating kinase
TPD52L2 tumor protein D52-like 2
TRAF3IP3 TRAF3 interacting protein 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB3 tribbles pseudokinase 3
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
UBA2 ubiquitin-like modifier activating enzyme 2
UBC ubiquitin C
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2I ubiquitin-conjugating enzyme E2I
UNC79 unc-79 homolog (C. elegans)
USP39 ubiquitin specific peptidase 39
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WDR35 WD repeat domain 35
WDR4 WD repeat domain 4
WNK4 WNK lysine deficient protein kinase 4
WNT16 wingless-type MMTV integration site family, member 16
YY1 YY1 transcription factor
ZMYND8 zinc finger, MYND-type containing 8
ZNF443 zinc finger protein 443