SAP30 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description Sin3A-associated protein, 30kDa|Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8819)
External Link https://ncbi.nlm.nih.gov/gene/8819
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Genes

500 genes differentially expressed following the SAP30 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAT2 acetyl-CoA acetyltransferase 2 0.0113007
S100A8 S100 calcium binding protein A8 0.0109898
PLN phospholamban 0.0106692
C3ORF14 chromosome 3 open reading frame 14 0.0106538
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.0106324
COMMD8 COMM domain containing 8 0.0100936
ENOPH1 enolase-phosphatase 1 0.00995219
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00990893
S100A9 S100 calcium binding protein A9 0.00986908
TFF3 trefoil factor 3 (intestinal) 0.0097104
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00965896
OLFM4 olfactomedin 4 0.00940831
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00934946
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00931742
NEBL nebulette 0.00894966
TXNDC9 thioredoxin domain containing 9 0.00879036
LGALS13 lectin, galactoside-binding, soluble, 13 0.00849117
PCP4 Purkinje cell protein 4 0.00842569
TLR4 toll-like receptor 4 0.00838959
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00835871
LYZ lysozyme 0.00834646
DACH1 dachshund family transcription factor 1 0.00816562
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0080686
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.0080317
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00799585
SEC23A Sec23 homolog A (S. cerevisiae) 0.00782428
EPHB2 EPH receptor B2 0.00781804
RTN1 reticulon 1 0.00776892
EVI2A ecotropic viral integration site 2A 0.0077215
MARCKSL1 MARCKS-like 1 0.00771737
MAP7 microtubule-associated protein 7 0.00760256
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00753451
SRGN serglycin 0.00741458
GCA grancalcin, EF-hand calcium binding protein 0.00740336
THBS1 thrombospondin 1 0.00739242
RNASE6 ribonuclease, RNase A family, k6 0.00735844
CSTA cystatin A (stefin A) 0.00730867
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.0072944
GCHFR GTP cyclohydrolase I feedback regulator 0.0072699
TMEM14A transmembrane protein 14A 0.00723574
DPYSL2 dihydropyrimidinase-like 2 0.00721722
TOX3 TOX high mobility group box family member 3 0.00718826
DCK deoxycytidine kinase 0.00708948
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00708545
COPS4 COP9 signalosome subunit 4 0.00706824
CCR2 chemokine (C-C motif) receptor 2 0.00698176
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00697813
RAB32 RAB32, member RAS oncogene family 0.00694974
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00692436
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00678908
KIF20A kinesin family member 20A 0.00678018
TMSB15A thymosin beta 15a 0.00677524
WSB2 WD repeat and SOCS box containing 2 0.00672754
UBE2N ubiquitin-conjugating enzyme E2N 0.00669272
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00662313
MMP12 matrix metallopeptidase 12 0.00659967
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00658108
CST3 cystatin C 0.0065624
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00647692
S100A2 S100 calcium binding protein A2 0.00641375
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00640419
RANBP1 RAN binding protein 1 0.00638506
LST1 leukocyte specific transcript 1 0.00636926
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.00636663
PCLO piccolo presynaptic cytomatrix protein 0.0063298
CEMIP cell migration inducing protein, hyaluronan binding 0.00627574
NUAK1 NUAK family, SNF1-like kinase, 1 0.00626735
RNF43 ring finger protein 43 0.00624299
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00618057
FERMT1 fermitin family member 1 0.00617736
MCM6 minichromosome maintenance complex component 6 0.00617006
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00614773
AMH anti-Mullerian hormone 0.00614161
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 0.00613962
ACKR3 atypical chemokine receptor 3 0.00611845
NSL1 NSL1, MIS12 kinetochore complex component 0.00611692
TMX1 thioredoxin-related transmembrane protein 1 0.00610158
SPTSSA serine palmitoyltransferase, small subunit A 0.00609481
PHTF2 putative homeodomain transcription factor 2 0.00609141
H2AZ1 H2A.Z variant histone 1 0.00608965
ACTL6A actin-like 6A 0.00605468
CENPU centromere protein U 0.00603735
MNDA myeloid cell nuclear differentiation antigen 0.00603672
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00602648
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00599001
KRT19 keratin 19, type I 0.00598144
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00597943
CD200 CD200 molecule 0.00595541
SAP30 Sin3A-associated protein, 30kDa 0.00594992
EFHD2 EF-hand domain family, member D2 0.00592393
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00590182
CIAO3 cytosolic iron-sulfur assembly component 3 0.00589919
GPX2 glutathione peroxidase 2 0.00589457
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00589443
FGL2 fibrinogen-like 2 0.00586757
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00586186
NTAQ1 N-terminal glutamine amidase 1 0.00585357
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00584183
FABP6 fatty acid binding protein 6, ileal 0.00580299
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00579176
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00578428
NREP neuronal regeneration related protein 0.00573888
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00570027
PAK1IP1 PAK1 interacting protein 1 0.00569566
REG1B regenerating islet-derived 1 beta 0.00569181
AKR1C3 aldo-keto reductase family 1, member C3 0.00567842
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00565635
HPCAL1 hippocalcin-like 1 0.00565567
SNX10 sorting nexin 10 0.0056549
CLEC10A C-type lectin domain family 10, member A 0.00564019
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00563874
MSMO1 methylsterol monooxygenase 1 0.00561676
ASPN asporin 0.00560339
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00559194
TCEAL1 transcription elongation factor A (SII)-like 1 0.00558241
TP53TG1 TP53 target 1 (non-protein coding) 0.00557456
CCNB1 cyclin B1 0.00554838
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00554203
HMGB2 high mobility group box 2 0.00554073
CCNE2 cyclin E2 0.00553609
TCEAL2 transcription elongation factor A (SII)-like 2 0.0055323
LMNB1 lamin B1 0.00553166
ABHD10 abhydrolase domain containing 10 0.00549769
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00549354
TFF1 trefoil factor 1 0.00548514
HAUS4 HAUS augmin-like complex, subunit 4 0.00547525
FGF13 fibroblast growth factor 13 0.00545346
HBB hemoglobin, beta 0.00544858
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00544449
MRPL48 mitochondrial ribosomal protein L48 0.00543723
PLAT plasminogen activator, tissue 0.00541605
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.00541232
WASHC3 WASH complex subunit 3 0.00540433
REG1A regenerating islet-derived 1 alpha 0.00538892
MRPL13 mitochondrial ribosomal protein L13 0.00538187
PDLIM3 PDZ and LIM domain 3 0.0053644
GZMK granzyme K (granzyme 3; tryptase II) 0.00536009
ZNF652 zinc finger protein 652 0.00535884
FASN fatty acid synthase 0.00535633
HEPH hephaestin 0.00535358
S100P S100 calcium binding protein P 0.00534918
KRT20 keratin 20, type I 0.00533727
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00533396
PTPRD protein tyrosine phosphatase, receptor type, D 0.00532708
NPM3 nucleophosmin/nucleoplasmin 3 0.00532693
CLCA1 chloride channel accessory 1 0.00531453
CDC7 cell division cycle 7 0.00530761
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00530091
CCNA2 cyclin A2 0.00529896
RHOB ras homolog family member B 0.00528717
NUP85 nucleoporin 85kDa 0.00526307
DCXR dicarbonyl/L-xylulose reductase 0.00525399
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00524885
CRYL1 crystallin, lambda 1 0.00524188
VCAN versican 0.00524027
NFE2L3 nuclear factor, erythroid 2-like 3 0.00523947
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00523164
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00521462
AGR2 anterior gradient 2 0.00519485
TLR2 toll-like receptor 2 0.00519268
CENPX centromere protein X 0.00519144
MLF1 myeloid leukemia factor 1 0.00517053
NSF N-ethylmaleimide-sensitive factor 0.00516223
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00515923
TMEM14B transmembrane protein 14B 0.005158
CPE carboxypeptidase E 0.00515769
OIP5 Opa interacting protein 5 0.00513481
SEC24D SEC24 family member D 0.00512272
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00510796
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00508857
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00508808
C1QTNF3 C1q and tumor necrosis factor related protein 3 0.00507589
TSPAN1 tetraspanin 1 0.00507357
IL7 interleukin 7 0.00506479
MARCHF1 membrane associated ring-CH-type finger 1 0.00506021
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.00505902
CNTNAP2 contactin associated protein-like 2 0.00504551
RPA3 replication protein A3, 14kDa 0.00501647
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00500598
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00499414
ECT2 epithelial cell transforming 2 0.00498952
HHEX hematopoietically expressed homeobox 0.00498313
CD48 CD48 molecule 0.00498228
EXOSC4 exosome component 4 0.00497492
EAF2 ELL associated factor 2 0.0049689
PCLAF PCNA clamp associated factor 0.00496127
ATXN1 ataxin 1 0.00493796
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00492768
TMPO thymopoietin 0.0049235
C12ORF29 chromosome 12 open reading frame 29 0.00492141
VBP1 von Hippel-Lindau binding protein 1 0.00491292
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00489149
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00488714
BIRC5 baculoviral IAP repeat containing 5 0.00488559
DSCC1 DNA replication and sister chromatid cohesion 1 0.00488502
HMGB3 high mobility group box 3 0.00487968
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00487647
REG3A regenerating islet-derived 3 alpha 0.00487363
ANKRD49 ankyrin repeat domain 49 0.0048723
RRM2 ribonucleotide reductase M2 0.0048717
LGALS1 lectin, galactoside-binding, soluble, 1 0.00486646
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00486553
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00485888
CD300A CD300a molecule 0.00484579
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00484348
PPA2 pyrophosphatase (inorganic) 2 0.00483715
SYNGR3 synaptogyrin 3 0.00483694
SNX7 sorting nexin 7 0.00483449
SNAI2 snail family zinc finger 2 0.00483347
DEFA6 defensin, alpha 6, Paneth cell-specific 0.00482605
WDR61 WD repeat domain 61 0.00482525
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.004823
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00481847
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00481779
CLEC7A C-type lectin domain family 7, member A 0.00481593
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00481275
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.00480367
SRP9 signal recognition particle 9kDa 0.00480277
TMED7 transmembrane emp24 protein transport domain containing 7 0.00479542
CDC45 cell division cycle 45 0.00479509
IPO13 importin 13 0.00479339
ELOVL6 ELOVL fatty acid elongase 6 0.00479023
HNMT histamine N-methyltransferase 0.00478535
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00476902
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.0047651
CLEC4A C-type lectin domain family 4, member A 0.00473888
MB myoglobin 0.00473733
ZFAND1 zinc finger, AN1-type domain 1 0.0047363
LEFTY1 left-right determination factor 1 0.00472807
ANOS1 anosmin 1 0.00472509
ENO2 enolase 2 (gamma, neuronal) 0.00471772
AIF1 allograft inflammatory factor 1 0.00471135
ALPL alkaline phosphatase, liver/bone/kidney 0.0047087
LY86 lymphocyte antigen 86 0.00470793
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.00470648
CD2 CD2 molecule 0.00470397
TPK1 thiamin pyrophosphokinase 1 0.00469856
FOXA2 forkhead box A2 0.00469334
IRF6 interferon regulatory factor 6 0.00469205
SDC1 syndecan 1 0.00468893
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00468759
PLEK2 pleckstrin 2 0.00468699
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.00467961
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00467462
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00467435
SULF1 sulfatase 1 0.00466842
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00466648
BASP1 brain abundant, membrane attached signal protein 1 0.00466212
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00463215
RPS5 ribosomal protein S5 0.0046316

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0144976
SLPI secretory leukocyte peptidase inhibitor -0.0139666
IFI27 interferon, alpha-inducible protein 27 -0.0129206
SIRT3 sirtuin 3 -0.0118783
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0110029
HSPA1A heat shock 70kDa protein 1A -0.0106029
MGLL monoglyceride lipase -0.0106015
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0104486
BST2 bone marrow stromal cell antigen 2 -0.010286
MBD1 methyl-CpG binding domain protein 1 -0.0100978
DUSP5 dual specificity phosphatase 5 -0.0100254
C3 complement component 3 -0.00989549
TFPI2 tissue factor pathway inhibitor 2 -0.00945114
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00920938
KRT14 keratin 14, type I -0.00918796
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00915648
SFRP1 secreted frizzled-related protein 1 -0.00912431
MT1E metallothionein 1E -0.00903599
AQP1 aquaporin 1 (Colton blood group) -0.00895152
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00888515
OXTR oxytocin receptor -0.00875073
CPM carboxypeptidase M -0.0086983
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00862128
FGF9 fibroblast growth factor 9 -0.00858611
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00844078
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0083755
GSTP1 glutathione S-transferase pi 1 -0.00831343
ATF3 activating transcription factor 3 -0.00827909
TM9SF3 transmembrane 9 superfamily member 3 -0.0082598
TENT5A terminal nucleotidyltransferase 5A -0.00815878
STC2 stanniocalcin 2 -0.00814325
CRYAB crystallin, alpha B -0.0079477
SEC62 SEC62 homolog (S. cerevisiae) -0.00788763
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00787469
IRS2 insulin receptor substrate 2 -0.0078615
CLU clusterin -0.00784742
PPL periplakin -0.00779319
ASS1 argininosuccinate synthase 1 -0.0077148
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00769858
GPM6B glycoprotein M6B -0.00767772
EFNB2 ephrin-B2 -0.00747111
KRT23 keratin 23, type I -0.00744908
KLK5 kallikrein-related peptidase 5 -0.00741016
MX1 MX dynamin-like GTPase 1 -0.0073686
SCGB2A1 secretoglobin, family 2A, member 1 -0.00732041
KLK10 kallikrein-related peptidase 10 -0.00720231
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00713498
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00713127
ADAM10 ADAM metallopeptidase domain 10 -0.00711232
EIF5B eukaryotic translation initiation factor 5B -0.0070758
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00704757
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00703447
MET MET proto-oncogene, receptor tyrosine kinase -0.00701145
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00700308
USP47 ubiquitin specific peptidase 47 -0.00694572
IER5 immediate early response 5 -0.0069435
MT1M metallothionein 1M -0.00690833
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.0068791
RBPMS RNA binding protein with multiple splicing -0.00685577
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced -0.00685006
ADGRG2 adhesion G protein-coupled receptor G2 -0.00680737
KLK11 kallikrein-related peptidase 11 -0.00679065
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00678577
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00673074
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00671458
PALMD palmdelphin -0.00669175
CTSA cathepsin A -0.00668997
CRCT1 cysteine-rich C-terminal 1 -0.00666661
MT1H metallothionein 1H -0.0066405
INHBB inhibin, beta B -0.0066325
TACSTD2 tumor-associated calcium signal transducer 2 -0.00660988
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00655524
LAMP1 lysosomal-associated membrane protein 1 -0.00655395
AMOTL2 angiomotin like 2 -0.00655201
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00653312
EGR1 early growth response 1 -0.00652828
IFITM1 interferon induced transmembrane protein 1 -0.00651009
MT1X metallothionein 1X -0.00649653
HEATR1 HEAT repeat containing 1 -0.00645552
PRKD2 protein kinase D2 -0.00644808
RABAC1 Rab acceptor 1 (prenylated) -0.00643405
MT1HL1 metallothionein 1H-like 1 -0.00642679
HMOX1 heme oxygenase 1 -0.00641923
AQP3 aquaporin 3 (Gill blood group) -0.0064106
DEFB1 defensin, beta 1 -0.00640452
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00635801
KDM5A lysine (K)-specific demethylase 5A -0.00634343
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00630908
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00630816
KIF13B kinesin family member 13B -0.00625933
FUS FUS RNA binding protein -0.00620212
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00618414
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00612786
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00611801
ZNF281 zinc finger protein 281 -0.00608963
MMP7 matrix metallopeptidase 7 -0.00608498
GOLGB1 golgin B1 -0.00605834
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00604589
SCGB2A2 secretoglobin, family 2A, member 2 -0.00604305
PILRB paired immunoglobin-like type 2 receptor beta -0.00604303
KLF6 Kruppel-like factor 6 -0.00603113
MAOB monoamine oxidase B -0.00597937
SIK1 salt-inducible kinase 1 -0.00597628
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00596114
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -0.00594469
RETREG3 reticulophagy regulator family member 3 -0.00594165
KRT5 keratin 5, type II -0.00592995
MT1G metallothionein 1G -0.00591164
RASA4 RAS p21 protein activator 4 -0.00589356
MTUS1 microtubule associated tumor suppressor 1 -0.00588762
ANXA1 annexin A1 -0.00588336
PRDX1 peroxiredoxin 1 -0.00587411
PDZD2 PDZ domain containing 2 -0.00586219
GPNMB glycoprotein (transmembrane) nmb -0.00584665
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00583874
BRD4 bromodomain containing 4 -0.00581944
MT1F metallothionein 1F -0.00581853
ACADVL acyl-CoA dehydrogenase, very long chain -0.00580406
FNBP4 formin binding protein 4 -0.00579551
DSP desmoplakin -0.0057878
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00577853
FOXO1 forkhead box O1 -0.0057677
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00575859
SCGB1D2 secretoglobin, family 1D, member 2 -0.00573794
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00571362
ATF4 activating transcription factor 4 -0.00570015
NBPF10 neuroblastoma breakpoint family, member 10 -0.00569374
FGFR1 fibroblast growth factor receptor 1 -0.005689
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00563782
FGB fibrinogen beta chain -0.00563639
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00563391
FBLN5 fibulin 5 -0.00561591
CHMP2A charged multivesicular body protein 2A -0.00561345
RREB1 ras responsive element binding protein 1 -0.00560982
SOX4 SRY (sex determining region Y)-box 4 -0.00560714
IGFBP6 insulin-like growth factor binding protein 6 -0.00559414
WNK1 WNK lysine deficient protein kinase 1 -0.00559159
IFI44L interferon-induced protein 44-like -0.00558872
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00556604
ESR1 estrogen receptor 1 -0.0055656
EMP1 epithelial membrane protein 1 -0.00551295
MVP major vault protein -0.00550269
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00546714
GNAS GNAS complex locus -0.00545069
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00544691
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -0.00541467
MT2A metallothionein 2A -0.00541164
RND3 Rho family GTPase 3 -0.00539624
SEPHS2 selenophosphate synthetase 2 -0.00539529
CAV1 caveolin 1, caveolae protein, 22kDa -0.00539342
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.00536809
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.00533787
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00533467
PCDH9 protocadherin 9 -0.00533179
JAK1 Janus kinase 1 -0.00532143
GAS1 growth arrest-specific 1 -0.00531534
EIF6 eukaryotic translation initiation factor 6 -0.00531448
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.0053141
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00530773
THOC2 THO complex 2 -0.00530293
SRSF5 serine/arginine-rich splicing factor 5 -0.00526402
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00525247
MSL1 male-specific lethal 1 homolog (Drosophila) -0.00525162
RRBP1 ribosome binding protein 1 -0.0052465
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.00524401
GOLGA8A golgin A8 family, member A -0.00524187
KLK7 kallikrein-related peptidase 7 -0.00522884
APOL2 apolipoprotein L, 2 -0.0052082
KLF5 Kruppel-like factor 5 (intestinal) -0.00520354
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00520308
CHEK2 checkpoint kinase 2 -0.00520139
RHOF ras homolog family member F (in filopodia) -0.00519319
E2F2 E2F transcription factor 2 -0.00516841
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.00513408
MSX1 msh homeobox 1 -0.00512628
IGF2R insulin-like growth factor 2 receptor -0.00510731
KRT16 keratin 16, type I -0.0051033
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00509537
USP6NL USP6 N-terminal like -0.00509159
MRC2 mannose receptor, C type 2 -0.0050863
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00507884
USP9X ubiquitin specific peptidase 9, X-linked -0.00507244
NOTCH2 notch 2 -0.00507207
IGHMBP2 immunoglobulin mu binding protein 2 -0.00505765
C1S complement component 1, s subcomponent -0.00504886
DOCK9 dedicator of cytokinesis 9 -0.0050473
EGFR epidermal growth factor receptor -0.00503926
WBP4 WW domain binding protein 4 -0.00503413
PLAUR plasminogen activator, urokinase receptor -0.00503169
ZNF395 zinc finger protein 395 -0.00502571
NXF1 nuclear RNA export factor 1 -0.00501799
PIP prolactin-induced protein -0.00501408
APOL1 apolipoprotein L, 1 -0.0050033
AHNAK AHNAK nucleoprotein -0.00498839
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00498105
PINK1 PTEN induced putative kinase 1 -0.00495615
EDN3 endothelin 3 -0.00495604
KRT17 keratin 17, type I -0.0049544
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00494694
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00493283
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00491154
COL6A1 collagen, type VI, alpha 1 -0.00490877
EGR2 early growth response 2 -0.00490151
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00489845
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.00488451
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00487797
ABLIM1 actin binding LIM protein 1 -0.00487345
GLA galactosidase, alpha -0.00487129
KRT15 keratin 15, type I -0.00485638
WAPL WAPL cohesin release factor -0.00485301
SGK1 serum/glucocorticoid regulated kinase 1 -0.00484971
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.004847
CFB complement factor B -0.00484477
ADM adrenomedullin -0.00483395
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0048256
TNS1 tensin 1 -0.00482135
MYBPC1 myosin binding protein C, slow type -0.00481919
LAMB1 laminin, beta 1 -0.00481097
BRD2 bromodomain containing 2 -0.00480423
OLFML2A olfactomedin-like 2A -0.00480355
BTG1 B-cell translocation gene 1, anti-proliferative -0.00479991
MXRA5 matrix-remodelling associated 5 -0.00478973
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00478765
UBE2H ubiquitin-conjugating enzyme E2H -0.00478343
CD151 CD151 molecule (Raph blood group) -0.00477402
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00477223
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00476476
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00476456
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00473507
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.00473327
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.00473186
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00471015
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -0.0047019
MATN2 matrilin 2 -0.00469251
RBM26 RNA binding motif protein 26 -0.00468515
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.00468191
MARF1 meiosis regulator and mRNA stability factor 1 -0.00467245
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.0046721
FGA fibrinogen alpha chain -0.00466951
TOP1 topoisomerase (DNA) I -0.00466797
ECPAS Ecm29 proteasome adaptor and scaffold -0.00466745
NPY1R neuropeptide Y receptor Y1 -0.00466428
STX4 syntaxin 4 -0.00465642
EHD2 EH-domain containing 2 -0.00463713
BCL3 B-cell CLL/lymphoma 3 -0.0046314
S100A11 S100 calcium binding protein A11 -0.00461528
GYS1 glycogen synthase 1 (muscle) -0.0046131
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.00461017
KCTD9 potassium channel tetramerization domain containing 9 -0.00461009
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.00460953