SARS-CoV Infections Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9679506
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Genes

418 proteins participating in the SARS-CoV Infections pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACE2 angiotensin I converting enzyme 2
AGRN agrin
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANO1 anoctamin 1, calcium activated chloride channel
ANO10 anoctamin 10
ANO2 anoctamin 2, calcium activated chloride channel
ANO3 anoctamin 3
ANO4 anoctamin 4
ANO5 anoctamin 5
ANO6 anoctamin 6
ANO7 anoctamin 7
ANO8 anoctamin 8
ANO9 anoctamin 9
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
ARID4B AT rich interactive domain 4B (RBP1-like)
ATG14 autophagy related 14
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
B2M beta-2-microglobulin
BCL2L1 BCL2-like 1
BECN1 beclin 1, autophagy related
BLNK B-cell linker
BRD4 bromodomain containing 4
BRMS1 breast cancer metastasis suppressor 1
BST2 bone marrow stromal cell antigen 2
BTK Bruton agammaglobulinemia tyrosine kinase
CANX calnexin
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CHD3 chromodomain helicase DNA binding protein 3
CHD4 chromodomain helicase DNA binding protein 4
CHMP2A charged multivesicular body protein 2A
CHMP2B charged multivesicular body protein 2B
CHMP3 charged multivesicular body protein 3
CHMP4A charged multivesicular body protein 4A
CHMP4B charged multivesicular body protein 4B
CHMP4C charged multivesicular body protein 4C
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CHUK conserved helix-loop-helix ubiquitous kinase
CNBP CCHC-type zinc finger, nucleic acid binding protein
COMT catechol-O-methyltransferase
CRB3 crumbs family member 3
CRBN cereblon
CREBBP CREB binding protein
CSNK1A1 casein kinase 1, alpha 1
CTSL cathepsin L
CUL3 cullin 3
CYSLTR1 cysteinyl leukotriene receptor 1
DAD1 defender against cell death 1
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EP300 E1A binding protein p300
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
FKBP1A FK506 binding protein 1A, 12kDa
FKBP4 FK506 binding protein 4, 59kDa
FNTA farnesyltransferase, CAAX box, alpha
FNTB farnesyltransferase, CAAX box, beta
FURIN furin (paired basic amino acid cleaving enzyme)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FXYD1 FXYD domain containing ion transport regulator 1
FXYD2 FXYD domain containing ion transport regulator 2
FXYD3 FXYD domain containing ion transport regulator 3
FXYD4 FXYD domain containing ion transport regulator 4
FXYD6 FXYD domain containing ion transport regulator 6
FXYD7 FXYD domain containing ion transport regulator 7
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GANAB glucosidase, alpha; neutral AB
GATAD2A GATA zinc finger domain containing 2A
GATAD2B GATA zinc finger domain containing 2B
GEMIN2 gem (nuclear organelle) associated protein 2
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN5 gem (nuclear organelle) associated protein 5
GEMIN6 gem (nuclear organelle) associated protein 6
GEMIN7 gem (nuclear organelle) associated protein 7
GEMIN8 gem (nuclear organelle) associated protein 8
GJA1 gap junction protein, alpha 1, 43kDa
GOLGA7 golgin A7
GPC1 glypican 1
GPC2 glypican 2
GPC3 glypican 3
GPC4 glypican 4
GPC5 glypican 5
GPC6 glypican 6
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HAVCR1 hepatitis A virus cellular receptor 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMG20B high mobility group 20B
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPG2 heparan sulfate proteoglycan 2
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGLL5 immunoglobulin lambda-like polypeptide 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IL1R1 interleukin 1 receptor, type I
IL6R interleukin 6 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ISCU iron-sulfur cluster assembly enzyme
ISG15 ISG15 ubiquitin-like modifier
ITCH itchy E3 ubiquitin protein ligase
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDM1A lysine (K)-specific demethylase 1A
KEAP1 kelch-like ECH-associated protein 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNB1 karyopherin (importin) beta 1
LARP1 La ribonucleoprotein domain family, member 1
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
MAGT1 magnesium transporter 1
MAN1B1 mannosidase, alpha, class 1B, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MBD3 methyl-CpG binding domain protein 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGAT4C MGAT4 family, member C
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MOGS mannosyl-oligosaccharide glucosidase
MTA1 metastasis associated 1
MTA2 metastasis associated 1 family, member 2
MTA3 metastasis associated 1 family, member 3
NCK1 NCK adaptor protein 1
NDC1 NDC1 transmembrane nucleoporin
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRP1 neuropilin 1
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP160 nucleoporin 160kDa
NUP188 nucleoporin 188kDa
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP214 nucleoporin 214kDa
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
NUP42 nucleoporin 42
NUP43 nucleoporin 43kDa
NUP50 nucleoporin 50kDa
NUP54 nucleoporin 54kDa
NUP58 nucleoporin 58
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NUP98 nucleoporin 98kDa
PALS1 protein associated with LIN7 1, MAGUK p55 family member
PARP10 poly (ADP-ribose) polymerase family, member 10
PARP14 poly (ADP-ribose) polymerase family, member 14
PARP16 poly (ADP-ribose) polymerase family, member 16
PARP4 poly (ADP-ribose) polymerase family, member 4
PARP6 poly (ADP-ribose) polymerase family, member 6
PARP8 poly (ADP-ribose) polymerase family, member 8
PARP9 poly (ADP-ribose) polymerase family, member 9
PATJ PATJ crumbs cell polarity complex component
PCBP2 poly(rC) binding protein 2
PDCD1 programmed cell death 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PHF21A PHD finger protein 21A
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKLR pyruvate kinase, liver and RBC
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPIG peptidylprolyl isomerase G (cyclophilin G)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PRKCSH protein kinase C substrate 80K-H
PRMT1 protein arginine methyltransferase 1
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PYCARD PYD and CARD domain containing
RAE1 ribonucleic acid export 1
RANBP2 RAN binding protein 2
RB1 retinoblastoma 1
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCAN3 RCAN family member 3
RCOR1 REST corepressor 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RIGI RNA sensor RIG-I
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF135 ring finger protein 135
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPN1 ribophorin I
RPN2 ribophorin II
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15 ribosomal protein S15
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS21 ribosomal protein S21
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27 ribosomal protein S27
RPS27A ribosomal protein S27a
RPS27L ribosomal protein S27-like
RPS28 ribosomal protein S28
RPS29 ribosomal protein S29
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RPSA ribosomal protein SA
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SAP18 Sin3A-associated protein, 18kDa
SAP30 Sin3A-associated protein, 30kDa
SAP30L SAP30-like
SAR1B secretion associated, Ras related GTPase 1B
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEH1L SEH1-like (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFTPD surfactant protein D
SH3KBP1 SH3-domain kinase binding protein 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SIKE1 suppressor of IKBKE 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMN1 survival of motor neuron 1, telomeric
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPF small nuclear ribonucleoprotein polypeptide F
SNRPG small nuclear ribonucleoprotein polypeptide G
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SRPK1 SRSF protein kinase 1
SRPK2 SRSF protein kinase 2
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STING1 stimulator of interferon response cGAMP interactor 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SYK spleen tyrosine kinase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBK1 TANK-binding kinase 1
TJP1 tight junction protein 1
TKFC triokinase/FMN cyclase
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMPRSS2 transmembrane protease, serine 2
TOMM70 translocase of outer mitochondrial membrane 70
TPR translocated promoter region, nuclear basket protein
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TRIM4 tripartite motif containing 4
TUBB tubulin, beta class I
TUFM Tu translation elongation factor, mitochondrial
TUSC3 tumor suppressor candidate 3
TYK2 tyrosine kinase 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UVRAG UV radiation resistance associated
VAV1 vav 1 guanine nucleotide exchange factor
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBP1 Z-DNA binding protein 1
ZCRB1 zinc finger CCHC-type and RNA binding motif 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC2 zinc finger, DHHC-type containing 2
ZDHHC20 zinc finger, DHHC-type containing 20
ZDHHC3 zinc finger, DHHC-type containing 3
ZDHHC5 zinc finger, DHHC-type containing 5
ZDHHC8 zinc finger, DHHC-type containing 8
ZDHHC9 zinc finger, DHHC-type containing 9