SARS-CoV-2 activates/modulates innate and adaptive immune responses Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9705671
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Genes

126 proteins participating in the SARS-CoV-2 activates/modulates innate and adaptive immune responses pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ATG14 autophagy related 14
B2M beta-2-microglobulin
BECN1 beclin 1, autophagy related
CHUK conserved helix-loop-helix ubiquitous kinase
CNBP CCHC-type zinc finger, nucleic acid binding protein
CREBBP CREB binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
JAK1 Janus kinase 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LARP1 La ribonucleoprotein domain family, member 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
NDC1 NDC1 transmembrane nucleoporin
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP155 nucleoporin 155kDa
NUP160 nucleoporin 160kDa
NUP188 nucleoporin 188kDa
NUP205 nucleoporin 205kDa
NUP210 nucleoporin 210kDa
NUP214 nucleoporin 214kDa
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
NUP42 nucleoporin 42
NUP43 nucleoporin 43kDa
NUP50 nucleoporin 50kDa
NUP54 nucleoporin 54kDa
NUP58 nucleoporin 58
NUP62 nucleoporin 62kDa
NUP85 nucleoporin 85kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NUP98 nucleoporin 98kDa
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
POM121 POM121 transmembrane nucleoporin
POM121C POM121 transmembrane nucleoporin C
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAE1 ribonucleic acid export 1
RANBP2 RAN binding protein 2
RIGI RNA sensor RIG-I
RIPK2 receptor-interacting serine-threonine kinase 2
RNF135 ring finger protein 135
RPS27A ribosomal protein S27a
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEH1L SEH1-like (S. cerevisiae)
SFTPD surfactant protein D
SIKE1 suppressor of IKBKE 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STING1 stimulator of interferon response cGAMP interactor 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBK1 TANK-binding kinase 1
TKFC triokinase/FMN cyclase
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TOMM70 translocase of outer mitochondrial membrane 70
TPR translocated promoter region, nuclear basket protein
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
TRIM4 tripartite motif containing 4
TYK2 tyrosine kinase 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1