SART1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description squamous cell carcinoma antigen recognized by T cells|This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9092)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_SART1
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Genes

63 co-expressed genes for SART1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACP1 acid phosphatase 1, soluble
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
BCL7B B-cell CLL/lymphoma 7B
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CLIC1 chloride intracellular channel 1
COX4I1 cytochrome c oxidase subunit IV isoform 1
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DRG1 developmentally regulated GTP binding protein 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF2 eukaryotic translation elongation factor 2
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
FAM168B family with sequence similarity 168, member B
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
GDI2 GDP dissociation inhibitor 2
H3F3A H3 histone, family 3A
HDGF hepatoma-derived growth factor
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MRPL23 mitochondrial ribosomal protein L23
MRPL9 mitochondrial ribosomal protein L9
NACA nascent polypeptide-associated complex alpha subunit
NCL nucleolin
PCBP2 poly(rC) binding protein 2
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PUF60 poly-U binding splicing factor 60KDa
RALY RALY heterogeneous nuclear ribonucleoprotein
RNPS1 RNA binding protein S1, serine-rich domain
RPL10A ribosomal protein L10a
RPL18 ribosomal protein L18
RPL21 ribosomal protein L21
RPL24 ribosomal protein L24
RPL30 ribosomal protein L30
RPL6 ribosomal protein L6
RPLP2 ribosomal protein, large, P2
RPS12 ribosomal protein S12
RPS27A ribosomal protein S27a
RPS6 ribosomal protein S6
SART1 squamous cell carcinoma antigen recognized by T cells
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
STRAP serine/threonine kinase receptor associated protein
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
USP22 ubiquitin specific peptidase 22
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H15 zinc finger CCCH-type containing 15