SAS Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description A immortal human tongue-derived cell line cell that has the characteristics: Human cell line derived from tongue cancer. Squamous cell carcinoma. TKG0470(Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0051568)
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Genes

343 genes with high or low expression in SAS relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
FAM60A family with sequence similarity 60, member A 3.13073
CHMP2B charged multivesicular body protein 2B 2.70458
PDCD2 programmed cell death 2 2.39558
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.26981
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.23739
PROP1 PROP paired-like homeobox 1 2.22162
IL1A interleukin 1, alpha 2.21498
AADAC arylacetamide deacetylase 2.12403
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 2.113
TMEM40 transmembrane protein 40 2.09117
NMT2 N-myristoyltransferase 2 2.06521
CDK7 cyclin-dependent kinase 7 2.00866
JADE2 jade family PHD finger 2 2.00689
ADORA2B adenosine A2b receptor 1.98435
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.93652
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 1.92456
DBR1 debranching RNA lariats 1 1.92132
CLDN1 claudin 1 1.91314
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 1.88103
MYO1B myosin IB 1.87807
MT1M metallothionein 1M 1.87093
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.86948
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 1.86215
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 1.85353
PCNP PEST proteolytic signal containing nuclear protein 1.85204
AZIN1 antizyme inhibitor 1 1.84876
XDH xanthine dehydrogenase 1.83762
MT1H metallothionein 1H 1.8326
MYOG myogenin (myogenic factor 4) 1.81459
MRPL42 mitochondrial ribosomal protein L42 1.81163
VGLL3 vestigial-like family member 3 1.79982
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.76566
PCID2 PCI domain containing 2 1.75322
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.73024
MCM4 minichromosome maintenance complex component 4 1.71179
POLM polymerase (DNA directed), mu 1.70995
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 1.69644
ARFRP1 ADP-ribosylation factor related protein 1 1.69379
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 1.68964
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 1.68626
EMC2 ER membrane protein complex subunit 2 1.68624
MT1X metallothionein 1X 1.68229
FASTKD2 FAST kinase domains 2 1.6713
KLK13 kallikrein-related peptidase 13 1.65623
MT1G metallothionein 1G 1.65445
NUP107 nucleoporin 107kDa 1.64671
NUP155 nucleoporin 155kDa 1.64213
STK3 serine/threonine kinase 3 1.64084
CAB39 calcium binding protein 39 1.64042
KRAS Kirsten rat sarcoma viral oncogene homolog 1.63709
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.63609
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.63558
NUP37 nucleoporin 37kDa 1.63542
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.62557
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.62201
TRIP13 thyroid hormone receptor interactor 13 1.60676
EFHC2 EF-hand domain (C-terminal) containing 2 1.60158
PHF10 PHD finger protein 10 1.59214
FZD6 frizzled class receptor 6 1.5762
NIT2 nitrilase family, member 2 1.56738
TMEM11 transmembrane protein 11 1.56016
ATAD2 ATPase family, AAA domain containing 2 1.55758
SPAG1 sperm associated antigen 1 1.54378
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.54352
ADRB2 adrenoceptor beta 2, surface 1.54299
RPE ribulose-5-phosphate-3-epimerase 1.53833
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 1.52366
MLN motilin 1.52028
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 1.51278
DHRS7B dehydrogenase/reductase (SDR family) member 7B 1.50799
MCC mutated in colorectal cancers 1.50684
CGGBP1 CGG triplet repeat binding protein 1 1.50472
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.49946
PDCD6 programmed cell death 6 1.49875
TSEN2 TSEN2 tRNA splicing endonuclease subunit 1.49846
F3 coagulation factor III (thromboplastin, tissue factor) 1.49499
STX6 syntaxin 6 1.48839
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 1.48767
RASAL2 RAS protein activator like 2 1.48364
FASTKD3 FAST kinase domains 3 1.48275
RAD54B RAD54 homolog B (S. cerevisiae) 1.48258
CDC25A cell division cycle 25A 1.48207
IL1B interleukin 1, beta 1.47704
LAMC2 laminin, gamma 2 1.47558
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 1.47553
DSCC1 DNA replication and sister chromatid cohesion 1 1.47545
MT1F metallothionein 1F 1.47437
DUS4L dihydrouridine synthase 4-like (S. cerevisiae) 1.46219
FHL2 four and a half LIM domains 2 1.46131
ANAPC1 anaphase promoting complex subunit 1 1.46115
NEURL1 neuralized E3 ubiquitin protein ligase 1 1.4597
ADGRG6 adhesion G protein-coupled receptor G6 1.45815
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 1.4517
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 1.44998
HYI hydroxypyruvate isomerase (putative) 1.44578
SETD8 SET domain containing (lysine methyltransferase) 8 1.44437
GPR87 G protein-coupled receptor 87 1.4439
WWC1 WW and C2 domain containing 1 1.43664
IL33R interleukin 33 receptor 1.43559
IMMT inner membrane protein, mitochondrial 1.42473
RFC3 replication factor C (activator 1) 3, 38kDa 1.42373
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.42036
EED embryonic ectoderm development 1.41798
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.4172

low expression

Symbol Name Standardized Value
HCG18 HLA complex group 18 (non-protein coding) -3.53725
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -3.01713
SPHK2 sphingosine kinase 2 -2.89024
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -2.68653
FXYD2 FXYD domain containing ion transport regulator 2 -2.6746
GSTZ1 glutathione S-transferase zeta 1 -2.65858
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -2.6458
MCF2L MCF.2 cell line derived transforming sequence-like -2.62041
RAB33A RAB33A, member RAS oncogene family -2.4928
ANKMY1 ankyrin repeat and MYND domain containing 1 -2.4404
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.39277
IFT140 intraflagellar transport 140 -2.38843
SOX12 SRY (sex determining region Y)-box 12 -2.34407
CIC capicua transcriptional repressor -2.34039
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase -2.33155
UBQLN2 ubiquilin 2 -2.33067
CDK5 cyclin-dependent kinase 5 -2.30322
FRY furry homolog (Drosophila) -2.303
HIST1H2AC histone cluster 1, H2ac -2.30159
ANAPC2 anaphase promoting complex subunit 2 -2.27047
KAT2B K(lysine) acetyltransferase 2B -2.2632
CNOT3 CCR4-NOT transcription complex, subunit 3 -2.24159
COL14A1 collagen, type XIV, alpha 1 -2.23987
NSF N-ethylmaleimide-sensitive factor -2.22333
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.21754
KIAA0430 KIAA0430 -2.21685
KLHL26 kelch-like family member 26 -2.19873
BBS4 Bardet-Biedl syndrome 4 -2.19296
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.18487
RABAC1 Rab acceptor 1 (prenylated) -2.17932
TJP3 tight junction protein 3 -2.17929
RAPSN receptor-associated protein of the synapse -2.16906
THRAP3 thyroid hormone receptor associated protein 3 -2.16145
ZBTB17 zinc finger and BTB domain containing 17 -2.15366
TFF2 trefoil factor 2 -2.14608
ZNF184 zinc finger protein 184 -2.12601
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.12062
MCTP1 multiple C2 domains, transmembrane 1 -2.0848
TTC3 tetratricopeptide repeat domain 3 -2.08227
QPCTL glutaminyl-peptide cyclotransferase-like -2.07487
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -2.07369
HIST1H4E histone cluster 1, H4e -2.06058
EXOC7 exocyst complex component 7 -2.0528
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -2.03879
PARP16 poly (ADP-ribose) polymerase family, member 16 -2.03875
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.03824
FAM50A family with sequence similarity 50, member A -2.02869
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -2.02418
SFTPC surfactant protein C -2.02159
NARFL nuclear prelamin A recognition factor-like -2.0127
HIST1H2BI histone cluster 1, H2bi -2.00455
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -1.98977
SCAMP2 secretory carrier membrane protein 2 -1.97777
YY2 YY2 transcription factor -1.95417
STX4 syntaxin 4 -1.95341
C1QTNF3 C1q and tumor necrosis factor related protein 3 -1.94494
HIST1H2BK histone cluster 1, H2bk -1.92539
CYB561D2 cytochrome b561 family, member D2 -1.92132
CLIC2 chloride intracellular channel 2 -1.92013
DUSP8 dual specificity phosphatase 8 -1.91037
CCDC121 coiled-coil domain containing 121 -1.90859
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) -1.90239
PPP6R1 protein phosphatase 6, regulatory subunit 1 -1.89824
GAB2 GRB2-associated binding protein 2 -1.89757
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.89673
ARMC7 armadillo repeat containing 7 -1.89324
ATF5 activating transcription factor 5 -1.89224
PRR14 proline rich 14 -1.87349
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.87187
MUC3B mucin 3B, cell surface associated -1.86356
ATP13A1 ATPase type 13A1 -1.86168
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 -1.85495
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -1.83878
HDAC6 histone deacetylase 6 -1.83766
EPX eosinophil peroxidase -1.83149
ADGRB1 adhesion G protein-coupled receptor B1 -1.8256
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -1.82525
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -1.82459
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -1.81427
FBXO31 F-box protein 31 -1.81173
PMP2 peripheral myelin protein 2 -1.81055
SMR3A submaxillary gland androgen regulated protein 3A -1.81003
IKZF1 IKAROS family zinc finger 1 (Ikaros) -1.80836
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -1.80209
PHACTR4 phosphatase and actin regulator 4 -1.79574
GALNS galactosamine (N-acetyl)-6-sulfatase -1.79556
ZNF350 zinc finger protein 350 -1.7946
SRD5A3 steroid 5 alpha-reductase 3 -1.79432
MEGF9 multiple EGF-like-domains 9 -1.78927
MAP9 microtubule-associated protein 9 -1.78413
FOXN3 forkhead box N3 -1.77958
CLDN15 claudin 15 -1.77563
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.77051
KDM6B lysine (K)-specific demethylase 6B -1.76973
HIST1H2BF histone cluster 1, H2bf -1.76833
BTN2A1 butyrophilin, subfamily 2, member A1 -1.75629
ZNF222 zinc finger protein 222 -1.7558
LIN37 lin-37 DREAM MuvB core complex component -1.75401
DAPK1 death-associated protein kinase 1 -1.75051
MST1 macrophage stimulating 1 -1.74884
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -1.74639
SPARCL1 SPARC-like 1 (hevin) -1.72261
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.72074
CRMP1 collapsin response mediator protein 1 -1.71685
ZBTB22 zinc finger and BTB domain containing 22 -1.70599
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -1.7047
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -1.70405
MAGED2 melanoma antigen family D2 -1.70074
PLCH1 phospholipase C, eta 1 -1.69789
THUMPD1 THUMP domain containing 1 -1.69713
DCT dopachrome tautomerase -1.69201
SMTN smoothelin -1.67514
DCAF8 DDB1 and CUL4 associated factor 8 -1.67489
SCAND1 SCAN domain containing 1 -1.67463
ASRGL1 asparaginase like 1 -1.67427
GIMAP6 GTPase, IMAP family member 6 -1.67323
PPP6R2 protein phosphatase 6, regulatory subunit 2 -1.66941
ALAD aminolevulinate dehydratase -1.66351
TPP1 tripeptidyl peptidase I -1.65991
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 -1.65858
PHF21A PHD finger protein 21A -1.65788
SYNPO2L synaptopodin 2-like -1.65487
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 -1.65159
TRIM26 tripartite motif containing 26 -1.649
LMO2 LIM domain only 2 (rhombotin-like 1) -1.64781
ZNF749 zinc finger protein 749 -1.6463
ZNF276 zinc finger protein 276 -1.64621
HIST1H2BD histone cluster 1, H2bd -1.64445
TSC22D4 TSC22 domain family, member 4 -1.63976
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -1.63442
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.63434
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) -1.62658
APOOL apolipoprotein O-like -1.62218
FBRS fibrosin -1.62211
BCL2L10 BCL2-like 10 (apoptosis facilitator) -1.60788
PRPF31 pre-mRNA processing factor 31 -1.60665
HIST1H2AK histone cluster 1, H2ak -1.60287
GYG2 glycogenin 2 -1.60041
PMS2P4 postmeiotic segregation increased 2 pseudogene 4 -1.5962
ATM ATM serine/threonine kinase -1.59423
ZNF587 zinc finger protein 587 -1.59168
SCAMP3 secretory carrier membrane protein 3 -1.59059
ANKRD6 ankyrin repeat domain 6 -1.59029
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -1.58542
SLC35E2 solute carrier family 35, member E2 -1.58254
PLXND1 plexin D1 -1.5819
CLSTN3 calsyntenin 3 -1.57595
TNP2 transition protein 2 (during histone to protamine replacement) -1.57263
EDNRB endothelin receptor type B -1.57169
HYAL3 hyaluronoglucosaminidase 3 -1.56836
ZMYM3 zinc finger, MYM-type 3 -1.56735
RNF113A ring finger protein 113A -1.56699
PCDH11X protocadherin 11 X-linked -1.56499
SIRT2 sirtuin 2 -1.56072
CRTC1 CREB regulated transcription coactivator 1 -1.56007
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -1.5566
EPHA4 EPH receptor A4 -1.55406
CTIF CBP80/20-dependent translation initiation factor -1.55152
EDN3 endothelin 3 -1.54412
ZHX3 zinc fingers and homeoboxes 3 -1.54068
PTPRG protein tyrosine phosphatase, receptor type, G -1.5394
IPO13 importin 13 -1.53569
GJA8 gap junction protein, alpha 8, 50kDa -1.53229
IL1R2 interleukin 1 receptor, type II -1.5302
GCA grancalcin, EF-hand calcium binding protein -1.5291
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) -1.528
EMILIN1 elastin microfibril interfacer 1 -1.52767
TLN2 talin 2 -1.52718
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -1.52692
ZNF668 zinc finger protein 668 -1.52425
EPN1 epsin 1 -1.51839
TBC1D13 TBC1 domain family, member 13 -1.51708
GPC3 glypican 3 -1.51603
CCDC106 coiled-coil domain containing 106 -1.51063
MYEF2 myelin expression factor 2 -1.50815
DEAF1 DEAF1 transcription factor -1.50332
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -1.50284
ZC3H7B zinc finger CCCH-type containing 7B -1.50092
PAQR6 progestin and adipoQ receptor family member VI -1.49557
SARM1 sterile alpha and TIR motif containing 1 -1.49466
PRR4 proline rich 4 (lacrimal) -1.49346
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -1.49255
CAT catalase -1.49085
BBS9 Bardet-Biedl syndrome 9 -1.48987
MAP2K5 mitogen-activated protein kinase kinase 5 -1.48963
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -1.48885
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -1.48827
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -1.48678
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -1.48541
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -1.48525
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -1.48485
PPP2R5B protein phosphatase 2, regulatory subunit B', beta -1.48452
CALCOCO1 calcium binding and coiled-coil domain 1 -1.48081
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.48019
ACACB acetyl-CoA carboxylase beta -1.47998
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -1.47915
COLEC12 collectin sub-family member 12 -1.47813
MKL1 megakaryoblastic leukemia (translocation) 1 -1.47714
SEPHS2 selenophosphate synthetase 2 -1.47705
SMAD6 SMAD family member 6 -1.47665
KAT2A K(lysine) acetyltransferase 2A -1.47639
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -1.47336
RIC8A RIC8 guanine nucleotide exchange factor A -1.47045
C1QL1 complement component 1, q subcomponent-like 1 -1.46633
SCN5A sodium channel, voltage gated, type V alpha subunit -1.46519
KIAA0232 KIAA0232 -1.46403
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -1.45978
BBS1 Bardet-Biedl syndrome 1 -1.45926
RPS27L ribosomal protein S27-like -1.45914
MAN2B1 mannosidase, alpha, class 2B, member 1 -1.45887
SLC22A17 solute carrier family 22, member 17 -1.45788
NUCB1 nucleobindin 1 -1.45768
MAGEH1 melanoma antigen family H1 -1.45727
ZNF444 zinc finger protein 444 -1.45675
C2CD2L C2CD2-like -1.45333
TBC1D17 TBC1 domain family, member 17 -1.45281
FBXL7 F-box and leucine-rich repeat protein 7 -1.45146
LZTR1 leucine-zipper-like transcription regulator 1 -1.45103
SRRM2 serine/arginine repetitive matrix 2 -1.45068
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -1.44975
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -1.44826
ZNF248 zinc finger protein 248 -1.44561
ZNF576 zinc finger protein 576 -1.44429
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.4385
EGFL6 EGF-like-domain, multiple 6 -1.43482
MPI mannose phosphate isomerase -1.4318
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -1.42992
PHKG1 phosphorylase kinase, gamma 1 (muscle) -1.42946
POU3F2 POU class 3 homeobox 2 -1.42823
NADK NAD kinase -1.42604
DNM2 dynamin 2 -1.42486
STOML1 stomatin (EPB72)-like 1 -1.42435
NAGLU N-acetylglucosaminidase, alpha -1.42182
SOAT2 sterol O-acyltransferase 2 -1.42008
KAT8 K(lysine) acetyltransferase 8 -1.41986
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.41906
ADGRL3 adhesion G protein-coupled receptor L3 -1.41898
TGOLN2 trans-golgi network protein 2 -1.41834
RFPL3S RFPL3 antisense -1.41662