SATB1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description SATB homeobox 1|This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 6304)
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Genes

322 genes differentially expressed following the SATB1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
MEP1B meprin A, beta 4.22269
VCX variable charge, X-linked 4.22269
FBXO47 F-box protein 47 4.22269
CORO6 coronin 6 4.22269
ACSL1 acyl-CoA synthetase long-chain family member 1 4.22269
ASB9 ankyrin repeat and SOCS box containing 9 4.22269
GPR83 G protein-coupled receptor 83 4.22269
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 4.22269
PIWIL3 piwi-like RNA-mediated gene silencing 3 4.22269
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 4.22269
TCEA3 transcription elongation factor A (SII), 3 4.22269
EPX eosinophil peroxidase 4.22269
UCN urocortin 4.22269
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 4.22269
H2BC1 H2B clustered histone 1 4.22269
KASH5 KASH domain containing 5 4.22269
TEX29 testis expressed 29 4.22269
TPPP tubulin polymerization promoting protein 4.22269
CTRB1 chymotrypsinogen B1 4.22269
IL23R interleukin 23 receptor 4.22269
SPATA31G1 SPATA31 subfamily G member 1 4.22269
SPATA31H1 SPATA31 subfamily H member 1 4.22269
NIBAN3 niban apoptosis regulator 3 4.22269
SEPTIN12 septin 12 4.22269
SPINK4 serine peptidase inhibitor, Kazal type 4 4.18576
FGL2 fibrinogen-like 2 4.18576
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 4.18576
HGD homogentisate 1,2-dioxygenase 4.18576
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 4.18576
WDR87 WD repeat domain 87 4.18576
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 4.18576
LEP leptin 4.18576
CARD16 caspase recruitment domain family, member 16 4.18576
FGF21 fibroblast growth factor 21 4.18576
LRRD1 leucine-rich repeats and death domain containing 1 4.18576
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 4.18576
SELPLG selectin P ligand 4.18576
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 4.18576
SH2D6 SH2 domain containing 6 4.18576
FETUB fetuin B 4.18576
ASB12 ankyrin repeat and SOCS box containing 12 4.18576
KLLN killin, p53-regulated DNA replication inhibitor 4.18576
MYO1A myosin IA 4.18576
JCHAIN joining chain of multimeric IgA and IgM 4.18576
ASB10 ankyrin repeat and SOCS box containing 10 4.18576
ATOH8 atonal homolog 8 (Drosophila) 4.18576
BFSP2 beaded filament structural protein 2, phakinin 4.18576
CRYGC crystallin, gamma C 4.18576
HBM hemoglobin, mu 4.18576
DLX4 distal-less homeobox 4 4.18576
SPAG6 sperm associated antigen 6 4.18576
NLRP10 NLR family, pyrin domain containing 10 4.18576
FAM9A family with sequence similarity 9, member A 4.18576
ADAD2 adenosine deaminase domain containing 2 4.18576
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 4.18576
SLC30A4 solute carrier family 30 (zinc transporter), member 4 4.18576
TAS2R10 taste receptor, type 2, member 10 4.18576
SP6 Sp6 transcription factor 4.18576
FOLR1 folate receptor 1 (adult) 4.18576
CIMIP2B ciliary microtubule inner protein 2B 4.18576
ACER1 alkaline ceramidase 1 4.18576
SPI1 Spi-1 proto-oncogene 4.18576
SPEM1 spermatid maturation 1 4.18576
LOC128125816 uncharacterized LOC128125816 4.18576
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 4.18576
PAPOLB poly(A) polymerase beta (testis specific) 4.18576
TMEM40 transmembrane protein 40 4.18576
COX8C cytochrome c oxidase subunit VIIIC 4.18576
VN1R2 vomeronasal 1 receptor 2 4.18576
CD300LF CD300 molecule-like family member f 4.18576
CAPN9 calpain 9 4.18576
PNMA6F PNMA family member 6F 4.18576
CFAP206 cilia and flagella associated protein 206 4.18576
GARIN1A golgi associated RAB2 interactor 1A 4.18576
DIPK1C divergent protein kinase domain 1C 4.18576
SPATA46 spermatogenesis associated 46 4.18576
FYB1 FYN binding protein 1 4.18576
SPATS1 spermatogenesis associated, serine-rich 1 4.18576
ROPN1B rhophilin associated tail protein 1B 4.18576
ABHD15 abhydrolase domain containing 15 4.18576
PTH parathyroid hormone 4.18576
SAA4 serum amyloid A4, constitutive 4.18576
CRLF2 cytokine receptor-like factor 2 4.18576
PCDHB10 protocadherin beta 10 4.18576
PCDHB11 protocadherin beta 11 4.18576
FOXD1 forkhead box D1 4.18576
FOXD4 forkhead box D4 4.18576
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 4.18576
FABP9 fatty acid binding protein 9, testis 4.18576
NCBP2L nuclear cap binding protein subunit 2-like 4.18576
EDAR ectodysplasin A receptor 4.18576
CATSPER3 cation channel, sperm associated 3 4.18576
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 4.18576
UTS2 urotensin 2 4.18576
MS4A13 membrane-spanning 4-domains, subfamily A, member 13 4.18576
OR2L5 olfactory receptor, family 2, subfamily L, member 5 4.18576
C1QTNF9 C1q and tumor necrosis factor related protein 9 4.18576
C1QL2 complement component 1, q subcomponent-like 2 4.18576
CFAP45 cilia and flagella associated protein 45 4.18576
GDF10 growth differentiation factor 10 4.18576
AWAT2 acyl-CoA wax alcohol acyltransferase 2 4.18576
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 4.18576
OPRK1 opioid receptor, kappa 1 4.18576
PRTN3 proteinase 3 4.18576
ALAS2 5'-aminolevulinate synthase 2 4.18576
ZNF366 zinc finger protein 366 4.18576
PCDHGB5 protocadherin gamma subfamily B, 5 4.18576
KCNK4 potassium channel, two pore domain subfamily K, member 4 4.18576
GAGE10 G antigen 10 4.18576
RFPL1 ret finger protein-like 1 4.18576
HAMP hepcidin antimicrobial peptide 4.18576
NOG noggin 4.18576
PHOSPHO1 phosphatase, orphan 1 4.18576
PLA2G4B phospholipase A2, group IVB (cytosolic) 4.18576
SCN3A sodium channel, voltage gated, type III alpha subunit 4.18576
NUTM2A NUT family member 2A 4.18576
ALOX5AP arachidonate 5-lipoxygenase-activating protein 4.18576
TBC1D26 TBC1 domain family, member 26 4.18576
DBX2 developing brain homeobox 2 4.18576
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 4.18576
ACSM4 acyl-CoA synthetase medium-chain family member 4 4.18576
HSPB9 heat shock protein, alpha-crystallin-related, B9 4.18576
SPRN shadow of prion protein homolog (zebrafish) 4.18576
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 4.18576
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 4.18576
BTNL3 butyrophilin-like 3 4.18576
PTPN20 protein tyrosine phosphatase, non-receptor type 20 4.18576
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 4.18576
OR4D2 olfactory receptor, family 4, subfamily D, member 2 4.18576
RGS4 regulator of G-protein signaling 4 4.18576
OR13G1 olfactory receptor, family 13, subfamily G, member 1 4.18576
TSPAN19 tetraspanin 19 4.18576
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 4.18576
GOLGA8R golgin A8 family, member R 4.18576
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 4.18576
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 4.18576
KLK11 kallikrein-related peptidase 11 4.18576
SMIM23 small integral membrane protein 23 4.18576
KLHL41 kelch-like family member 41 4.18576
SPINK9 serine peptidase inhibitor, Kazal type 9 4.18576
TMED6 transmembrane emp24 protein transport domain containing 6 4.18576
MAB21L1 mab-21-like 1 (C. elegans) 4.18576
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 4.18576
DRD4 dopamine receptor D4 4.18576
PCDHGA4 protocadherin gamma subfamily A, 4 4.18576
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 4.18576
LY6G6C lymphocyte antigen 6 complex, locus G6C 4.18576
TMEM88 transmembrane protein 88 4.18576
METTL21C methyltransferase like 21C 4.18576
STOML3 stomatin (EPB72)-like 3 4.18576
IFNK interferon, kappa 4.18576
TGM6 transglutaminase 6 4.18576
FAM81B family with sequence similarity 81, member B 4.18576
ISX intestine-specific homeobox 4.18576
CD34 CD34 molecule 4.18576
AREG amphiregulin 4.18576
NRGN neurogranin (protein kinase C substrate, RC3) 4.18576
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 4.18576
PCDHGA12 protocadherin gamma subfamily A, 12 4.18576
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 4.18576
CCDC87 coiled-coil domain containing 87 4.18576
SLCO1C1 solute carrier organic anion transporter family, member 1C1 4.18576
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 4.18576
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 4.18576
TRPM5 transient receptor potential cation channel, subfamily M, member 5 4.18576
TUBAL3 tubulin, alpha-like 3 4.18576
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 4.09512
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 4.09512
TMEM154 transmembrane protein 154 3.89306
NUP88 nucleoporin 88kDa 3.73868
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 3.56197
CFAP73 cilia and flagella associated protein 73 3.56197
RALYL RALY RNA binding protein-like 3.50363
BBLN bublin coiled coil protein 3.40472
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 3.29606
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 3.17796
POT1 protection of telomeres 1 3.17796
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 3.0439
C2ORF81 chromosome 2 open reading frame 81 2.98048
IGSF22 immunoglobulin superfamily, member 22 2.98048
ROPN1L rhophilin associated tail protein 1-like 2.98048
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.98048
CPLX4 complexin 4 2.91721
PITPNA phosphatidylinositol transfer protein, alpha 2.88463
ETAA1 Ewing tumor-associated antigen 1 2.77635
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.72063
USP51 ubiquitin specific peptidase 51 2.70899
BIN1 bridging integrator 1 2.70654
HACD4 3-hydroxyacyl-CoA dehydratase 4 2.6953
LDLRAP1 low density lipoprotein receptor adaptor protein 1 2.6902
GORASP1 golgi reassembly stacking protein 1, 65kDa 2.65853
BCAS3 breast carcinoma amplified sequence 3 2.6373
LRP6 low density lipoprotein receptor-related protein 6 2.50629
AOX1 aldehyde oxidase 1 2.49928
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils 2.49329
GREB1L growth regulation by estrogen in breast cancer-like 2.43947
TAS2R20 taste receptor, type 2, member 20 2.40662
FPGT fucose-1-phosphate guanylyltransferase 2.37276
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.36491
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.36491
PRCD progressive rod-cone degeneration 2.36491
KIAA0232 KIAA0232 2.33146
KPNB1 karyopherin (importin) beta 1 2.32058
ZFYVE27 zinc finger, FYVE domain containing 27 2.31574
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.27144
MCHR1 melanin-concentrating hormone receptor 1 2.27144
EIF2D eukaryotic translation initiation factor 2D 2.25954
IFI35 interferon-induced protein 35 2.24727
CDK14 cyclin-dependent kinase 14 2.24727
SETD5 SET domain containing 5 2.24425
CHIC1 cysteine-rich hydrophobic domain 1 2.22866
FMO2 flavin containing monooxygenase 2 (non-functional) 2.22119
CENPO centromere protein O 2.22094
AOAH acyloxyacyl hydrolase (neutrophil) 2.20608
MAP7D1 MAP7 domain containing 1 2.17614
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 2.17614
MYCT1 myc target 1 2.17614
NT5E 5'-nucleotidase, ecto (CD73) 2.17614
DPH6 diphthamine biosynthesis 6 2.15625
LEMD1 LEM domain containing 1 2.1327
NDC80 NDC80 kinetochore complex component 2.13013
FBXL20 F-box and leucine-rich repeat protein 20 2.11748
TBCEL tubulin folding cofactor E-like 2.11637
STPG1 sperm-tail PG-rich repeat containing 1 2.11007
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.10088
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.09906
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 2.07332
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 2.02573
ANKRD13C ankyrin repeat domain 13C 2.02241
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 2.01978

decreased expression

Symbol Name Standardized Value
NICN1 nicolin 1 -4.22269
ACBD4 acyl-CoA binding domain containing 4 -4.22269
AQP3 aquaporin 3 (Gill blood group) -4.22269
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -4.22269
CHL1 cell adhesion molecule L1-like -4.18576
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -4.18576
TMEM100 transmembrane protein 100 -4.18576
NANOS3 nanos homolog 3 (Drosophila) -4.18576
CATSPERT catsper channel auxiliary subunit tau -4.18576
TLE6 transducin-like enhancer of split 6 -4.18576
SLC15A5 solute carrier family 15, member 5 -4.18576
CHAD chondroadherin -4.18576
CAPS calcyphosine -4.18576
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -4.18576
DIO1 deiodinase, iodothyronine, type I -4.18576
ARRDC2 arrestin domain containing 2 -4.18576
PITX2 paired-like homeodomain 2 -4.18576
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -4.18576
MMP19 matrix metallopeptidase 19 -4.18576
GPR20 G protein-coupled receptor 20 -4.18576
TPTE transmembrane phosphatase with tensin homology -4.18576
FIMP1 fertilization-influencing membrane protein 1 -4.18576
SYNGR4 synaptogyrin 4 -4.18576
EPHA5 EPH receptor A5 -4.18576
RIPPLY2 ripply transcriptional repressor 2 -4.18576
TCAP titin-cap -4.18576
YPEL4 yippee-like 4 (Drosophila) -4.18576
SPATA16 spermatogenesis associated 16 -4.18576
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -4.18576
PEBP4 phosphatidylethanolamine-binding protein 4 -4.18576
THSD8 thrombospondin type 1 domain containing 8 -4.18576
KLHL1 kelch-like family member 1 -4.18576
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -4.18576
PLCZ1 phospholipase C, zeta 1 -4.18576
NSL1 NSL1, MIS12 kinetochore complex component -3.85979
MBTPS2 membrane-bound transcription factor peptidase, site 2 -3.31447
THAP5 THAP domain containing 5 -3.12507
PRR13 proline rich 13 -3.10075
SNX1 sorting nexin 1 -3.06716
DCLK3 doublecortin-like kinase 3 -3.0369
PACRGL PARK2 co-regulated-like -2.91721
USP1 ubiquitin specific peptidase 1 -2.88038
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -2.86507
MOGAT1 monoacylglycerol O-acyltransferase 1 -2.86498
NEK3 NIMA-related kinase 3 -2.85086
MAP6D1 MAP6 domain containing 1 -2.85086
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.85086
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.76677
ZFR2 zinc finger RNA binding protein 2 -2.75187
ZNF774 zinc finger protein 774 -2.74701
F10 coagulation factor X -2.74701
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.68284
AP1M1 adaptor-related protein complex 1, mu 1 subunit -2.66653
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -2.63826
ASXL2 additional sex combs like transcriptional regulator 2 -2.6373
LCK LCK proto-oncogene, Src family tyrosine kinase -2.58051
DACT2 dishevelled-binding antagonist of beta-catenin 2 -2.56222
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -2.46369
CCNB1 cyclin B1 -2.45406
FYCO1 FYVE and coiled-coil domain containing 1 -2.4159
PDF peptide deformylase (mitochondrial) -2.41467
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -2.38734
OTUD3 OTU deubiquitinase 3 -2.35011
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -2.35011
LHCGR luteinizing hormone/choriogonadotropin receptor -2.34866
B2M beta-2-microglobulin -2.32058
ZNF239 zinc finger protein 239 -2.27783
FBXO32 F-box protein 32 -2.27144
RGPD1 RANBP2-like and GRIP domain containing 1 -2.27144
FBH1 F-box DNA helicase 1 -2.25841
ZNF627 zinc finger protein 627 -2.25157
PCED1A PC-esterase domain containing 1A -2.22648
CFAP119 cilia and flagella associated protein 119 -2.22119
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.22119
SLFNL1 schlafen-like 1 -2.22091
TACR1 tachykinin receptor 1 -2.20012
CLUH clustered mitochondria (cluA/CLU1) homolog -2.15798
TUSC1 tumor suppressor candidate 1 -2.15625
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -2.14852
RBP7 retinol binding protein 7, cellular -2.14795
SLC25A35 solute carrier family 25, member 35 -2.14528
ABHD11 abhydrolase domain containing 11 -2.1327
SVIP small VCP/p97-interacting protein -2.1239
MRPS36 mitochondrial ribosomal protein S36 -2.12241
BIN3 bridging integrator 3 -2.12241
SAP25 Sin3A-associated protein, 25kDa -2.11748
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) -2.11748
CPEB4 cytoplasmic polyadenylation element binding protein 4 -2.11637
DAPK1 death-associated protein kinase 1 -2.10088
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -2.09639
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.07384
LEPROTL1 leptin receptor overlapping transcript-like 1 -2.01148