| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | Shwachman-Bodian-Diamond syndrome|This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 51119) |
| External Link | https://ncbi.nlm.nih.gov/gene/51119 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the SBDS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.0135963 |
| IPO13 | importin 13 | 0.0131723 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0127502 |
| HIST1H2BD | histone cluster 1, H2bd | 0.01238 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0118111 |
| PLK2 | polo-like kinase 2 | 0.0116234 |
| MX1 | MX dynamin-like GTPase 1 | 0.011437 |
| ATF3 | activating transcription factor 3 | 0.011369 |
| IFI44 | interferon-induced protein 44 | 0.0112202 |
| LXN | latexin | 0.0111002 |
| RND3 | Rho family GTPase 3 | 0.0110597 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0110338 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0109714 |
| TRIM29 | tripartite motif containing 29 | 0.010909 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0108863 |
| S100A9 | S100 calcium binding protein A9 | 0.0107123 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0106386 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0105889 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0105342 |
| IFI44L | interferon-induced protein 44-like | 0.0103475 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0101511 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0101503 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0100935 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00974316 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00967042 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00950796 |
| RRAGD | Ras-related GTP binding D | 0.00949284 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00945907 |
| REG1A | regenerating islet-derived 1 alpha | 0.00945902 |
| CFB | complement factor B | 0.0094092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00929448 |
| MX2 | MX dynamin-like GTPase 2 | 0.00915668 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00906705 |
| FRMD4B | FERM domain containing 4B | 0.00904004 |
| NUP50 | nucleoporin 50kDa | 0.00902852 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00897712 |
| ZNF91 | zinc finger protein 91 | 0.00892966 |
| REG1B | regenerating islet-derived 1 beta | 0.0088789 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00883865 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00881125 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00873874 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00869547 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00865531 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00861592 |
| MID1 | midline 1 | 0.00856722 |
| CD200 | CD200 molecule | 0.00856466 |
| PERP | PERP, TP53 apoptosis effector | 0.00854951 |
| XAF1 | XIAP associated factor 1 | 0.00854423 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00846147 |
| ANXA1 | annexin A1 | 0.00845878 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00839695 |
| STX3 | syntaxin 3 | 0.00838499 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00837223 |
| TFRC | transferrin receptor | 0.00825294 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00815709 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00814185 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00810139 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00801081 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00795915 |
| SNAI2 | snail family zinc finger 2 | 0.0079188 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00790464 |
| BEX4 | brain expressed, X-linked 4 | 0.00787515 |
| TRIB2 | tribbles pseudokinase 2 | 0.00784569 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0077715 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00776532 |
| GDF15 | growth differentiation factor 15 | 0.00774864 |
| INHBA | inhibin, beta A | 0.00772583 |
| AOC1 | amine oxidase, copper containing 1 | 0.00772536 |
| PDGFC | platelet derived growth factor C | 0.00771062 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00765867 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00763754 |
| HOXD1 | homeobox D1 | 0.00762108 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00761819 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00761209 |
| RPS27L | ribosomal protein S27-like | 0.00761003 |
| H1-2 | H1.2 linker histone, cluster member | 0.00760615 |
| MYO1B | myosin IB | 0.00752722 |
| KYNU | kynureninase | 0.00750091 |
| ASS1 | argininosuccinate synthase 1 | 0.00743819 |
| ZNF586 | zinc finger protein 586 | 0.00742036 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0074081 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00738816 |
| KRT23 | keratin 23, type I | 0.00737425 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00728351 |
| EVI2A | ecotropic viral integration site 2A | 0.00728347 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00722083 |
| HTRA1 | HtrA serine peptidase 1 | 0.00721879 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00720263 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.00720082 |
| SNX11 | sorting nexin 11 | 0.00719762 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0071564 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00715583 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00713596 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00712911 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00712868 |
| RHOB | ras homolog family member B | 0.00712435 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00711834 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00711832 |
| THBS1 | thrombospondin 1 | 0.00706899 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00704549 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00701095 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00700585 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00698988 |
| TGFA | transforming growth factor, alpha | 0.00697671 |
| PELO | pelota homolog (Drosophila) | 0.00697165 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00694899 |
| ZNF331 | zinc finger protein 331 | 0.00694223 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00691592 |
| LAMC2 | laminin, gamma 2 | 0.0069112 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00688471 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00684065 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00681031 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00680767 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00679859 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00678753 |
| HDAC9 | histone deacetylase 9 | 0.00678336 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00678033 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00677083 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00675845 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | 0.00674564 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00673513 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00671885 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00671325 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00671285 |
| SIRPA | signal-regulatory protein alpha | 0.00668739 |
| HMOX1 | heme oxygenase 1 | 0.00667637 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00667583 |
| GPX2 | glutathione peroxidase 2 | 0.00665901 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00661607 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00660142 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00658981 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00655258 |
| ZNF93 | zinc finger protein 93 | 0.00654364 |
| WWC1 | WW and C2 domain containing 1 | 0.00653704 |
| AHR | aryl hydrocarbon receptor | 0.00653076 |
| TMEM140 | transmembrane protein 140 | 0.0065031 |
| MGAM | maltase-glucoamylase | 0.00648629 |
| TGM2 | transglutaminase 2 | 0.00647852 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00646226 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00645619 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00643515 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.00642764 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00642668 |
| UPP1 | uridine phosphorylase 1 | 0.00642121 |
| ADIRF | adipogenesis regulatory factor | 0.00641564 |
| KLHL24 | kelch-like family member 24 | 0.00641274 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00638158 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00637728 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00636888 |
| PLIN2 | perilipin 2 | 0.00634704 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00631044 |
| S100A12 | S100 calcium binding protein A12 | 0.00629938 |
| CORO1C | coronin, actin binding protein, 1C | 0.00629785 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00629152 |
| S100A8 | S100 calcium binding protein A8 | 0.00628985 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00625898 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00624336 |
| CALB1 | calbindin 1, 28kDa | 0.00623529 |
| ZNF706 | zinc finger protein 706 | 0.00620475 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00618646 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00616981 |
| IER5 | immediate early response 5 | 0.00616685 |
| IL1R1 | interleukin 1 receptor, type I | 0.00615816 |
| YAP1 | Yes-associated protein 1 | 0.0061558 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00615261 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00614579 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00614152 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00613206 |
| MIR22HG | MIR22 host gene | 0.00611823 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00609892 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00609619 |
| KLK10 | kallikrein-related peptidase 10 | 0.00608111 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00608105 |
| GOLT1B | golgi transport 1B | 0.00607791 |
| ZNF430 | zinc finger protein 430 | 0.00606056 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00605268 |
| CLK4 | CDC-like kinase 4 | 0.0059757 |
| CHGB | chromogranin B | 0.00594442 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00593984 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 | 0.00593736 |
| PFDN4 | prefoldin subunit 4 | 0.00591983 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00591831 |
| SUSD4 | sushi domain containing 4 | 0.00591766 |
| JAG1 | jagged 1 | 0.0059174 |
| AFTPH | aftiphilin | 0.0059161 |
| DPEP1 | dipeptidase 1 (renal) | 0.00590234 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00587342 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0058672 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.00585783 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.00584527 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00584267 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00583527 |
| NOX4 | NADPH oxidase 4 | 0.00583074 |
| MMD | monocyte to macrophage differentiation-associated | 0.0058217 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00581901 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00581689 |
| MCOLN1 | mucolipin 1 | 0.00580905 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00580496 |
| SULF1 | sulfatase 1 | 0.00579241 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00578789 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.00578724 |
| IL1RN | interleukin 1 receptor antagonist | 0.00576755 |
| SP110 | SP110 nuclear body protein | 0.00575152 |
| CAST | calpastatin | 0.00574622 |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | 0.00573936 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00572428 |
| IRF9 | interferon regulatory factor 9 | 0.00571678 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00570964 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00569892 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00568498 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00564105 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00563171 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0056268 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00562621 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00562221 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00561686 |
| CTSD | cathepsin D | 0.00560815 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0056066 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | 0.0056045 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00560346 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00560341 |
| TBX3 | T-box 3 | 0.00559632 |
| BCL2A1 | BCL2-related protein A1 | 0.00557652 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00557226 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00557116 |
| ABHD5 | abhydrolase domain containing 5 | 0.00556726 |
| CD2AP | CD2-associated protein | 0.00556334 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00554777 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00554507 |
| SERINC1 | serine incorporator 1 | 0.00553603 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00552701 |
| HOXD3 | homeobox D3 | 0.00551387 |
| KLK7 | kallikrein-related peptidase 7 | 0.00551318 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00551189 |
| REXO2 | RNA exonuclease 2 | 0.00549423 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00549181 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00548739 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00547715 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00547502 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.00546969 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00546853 |
| DUSP5 | dual specificity phosphatase 5 | 0.00546203 |
| RRAGC | Ras-related GTP binding C | 0.00545775 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00545211 |
| RPL36 | ribosomal protein L36 | 0.00544808 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00544768 |
| RYBP | RING1 and YY1 binding protein | 0.00543245 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00542566 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SIRT3 | sirtuin 3 | -0.0166949 |
| SYNGR3 | synaptogyrin 3 | -0.0142998 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0129052 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0128979 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0123982 |
| HOPX | HOP homeobox | -0.0123787 |
| ANXA6 | annexin A6 | -0.0121815 |
| AGR2 | anterior gradient 2 | -0.0121548 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.0118448 |
| PTCH1 | patched 1 | -0.0118196 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0116996 |
| SRPX | sushi-repeat containing protein, X-linked | -0.011652 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0113393 |
| MYBPC1 | myosin binding protein C, slow type | -0.010457 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.0104325 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.0103205 |
| C1R | complement component 1, r subcomponent | -0.0101734 |
| CDC20 | cell division cycle 20 | -0.0101664 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.0100316 |
| TNNC1 | troponin C type 1 (slow) | -0.00997328 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00995195 |
| BCHE | butyrylcholinesterase | -0.00988326 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00981466 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00954415 |
| MSX1 | msh homeobox 1 | -0.00950479 |
| GPM6A | glycoprotein M6A | -0.00936744 |
| CLU | clusterin | -0.00912653 |
| ITM2A | integral membrane protein 2A | -0.00912349 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00911758 |
| GAS1 | growth arrest-specific 1 | -0.0090681 |
| NES | nestin | -0.00905044 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00903421 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00874757 |
| SYNM | synemin, intermediate filament protein | -0.00866079 |
| MXRA7 | matrix-remodelling associated 7 | -0.00858534 |
| FBLN5 | fibulin 5 | -0.00856839 |
| CD99 | CD99 molecule | -0.0085085 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00849829 |
| NRN1 | neuritin 1 | -0.00828737 |
| NKG7 | natural killer cell granule protein 7 | -0.00824315 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00824025 |
| FABP7 | fatty acid binding protein 7, brain | -0.00822239 |
| DMD | dystrophin | -0.00820919 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00819182 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00818992 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00818664 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00818391 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00816037 |
| TPM2 | tropomyosin 2 (beta) | -0.00815025 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00813962 |
| NKX2-2 | NK2 homeobox 2 | -0.00813903 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.0081204 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0080786 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00806567 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00796314 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0078909 |
| REEP1 | receptor accessory protein 1 | -0.00787871 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00787397 |
| TFF1 | trefoil factor 1 | -0.00785914 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00781455 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00779129 |
| TMEM255A | transmembrane protein 255A | -0.00773538 |
| CH25H | cholesterol 25-hydroxylase | -0.00764147 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00763552 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00763352 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00759788 |
| CHI3L2 | chitinase 3-like 2 | -0.00755814 |
| BEX1 | brain expressed, X-linked 1 | -0.00752194 |
| FSTL1 | follistatin-like 1 | -0.00742276 |
| PRF1 | perforin 1 (pore forming protein) | -0.00741866 |
| CFH | complement factor H | -0.00739713 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00739338 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00737883 |
| C1RL | complement component 1, r subcomponent-like | -0.00728043 |
| CD151 | CD151 molecule (Raph blood group) | -0.00722907 |
| BAD | BCL2-associated agonist of cell death | -0.00722698 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00718195 |
| PLK1 | polo-like kinase 1 | -0.00717944 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00715684 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -0.00714932 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00714883 |
| HMGB3 | high mobility group box 3 | -0.00713485 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.00710651 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00709231 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.00706538 |
| CLIC3 | chloride intracellular channel 3 | -0.00705989 |
| PGC | progastricsin (pepsinogen C) | -0.00702812 |
| RHOA | ras homolog family member A | -0.00702271 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.0069973 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00698875 |
| CALCA | calcitonin-related polypeptide alpha | -0.00698315 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00697832 |
| KIF20A | kinesin family member 20A | -0.00696713 |
| NLGN4X | neuroligin 4, X-linked | -0.0069601 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00695421 |
| TSPAN8 | tetraspanin 8 | -0.0069476 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00692042 |
| GSAP | gamma-secretase activating protein | -0.00688639 |
| PLTP | phospholipid transfer protein | -0.00688039 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00686831 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00682468 |
| OGN | osteoglycin | -0.0068041 |
| DENND2B | DENN domain containing 2B | -0.0067815 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00676035 |
| KRT1 | keratin 1, type II | -0.00674659 |
| RTN1 | reticulon 1 | -0.00673764 |
| IL2RB | interleukin 2 receptor, beta | -0.0067331 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00672599 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00670772 |
| PMP2 | peripheral myelin protein 2 | -0.00669704 |
| CD81 | CD81 molecule | -0.00666113 |
| SORD | sorbitol dehydrogenase | -0.00661537 |
| C1S | complement component 1, s subcomponent | -0.00660918 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00660857 |
| PGD | phosphogluconate dehydrogenase | -0.00660701 |
| EGR2 | early growth response 2 | -0.00660024 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00658319 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0065441 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00653318 |
| ARHGAP19 | Rho GTPase activating protein 19 | -0.00653108 |
| TBCD | tubulin folding cofactor D | -0.00650823 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00650745 |
| PLP1 | proteolipid protein 1 | -0.00649469 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00644196 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0064296 |
| GRB14 | growth factor receptor-bound protein 14 | -0.00642689 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00641163 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -0.00640056 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00639021 |
| CHKB | choline kinase beta | -0.00638676 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00638253 |
| CHEK2 | checkpoint kinase 2 | -0.0063756 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00637032 |
| TUBA1A | tubulin, alpha 1a | -0.00633951 |
| KLHL41 | kelch-like family member 41 | -0.00633692 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00632576 |
| LEPR | leptin receptor | -0.00632343 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00631208 |
| TMEM45A | transmembrane protein 45A | -0.00627789 |
| RAB20 | RAB20, member RAS oncogene family | -0.00627493 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00624017 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00623023 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.00621825 |
| SEPTIN10 | septin 10 | -0.00620285 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00617838 |
| SRR | serine racemase | -0.0061732 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00617229 |
| HOXB6 | homeobox B6 | -0.00616759 |
| MAGED1 | melanoma antigen family D1 | -0.00616655 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00614604 |
| NEFH | neurofilament, heavy polypeptide | -0.00614219 |
| GAL | galanin/GMAP prepropeptide | -0.00613542 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00612907 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | -0.00612193 |
| TIMELESS | timeless circadian clock | -0.00609064 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -0.00608937 |
| ADCY3 | adenylate cyclase 3 | -0.00607399 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00606681 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00606221 |
| OBSL1 | obscurin-like 1 | -0.00605743 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00604254 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00603992 |
| FASN | fatty acid synthase | -0.00602767 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00602624 |
| APMAP | adipocyte plasma membrane associated protein | -0.00602352 |
| COL3A1 | collagen, type III, alpha 1 | -0.00601236 |
| HYOU1 | hypoxia up-regulated 1 | -0.00600325 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00597479 |
| CA3 | carbonic anhydrase III | -0.00596005 |
| TXNIP | thioredoxin interacting protein | -0.00595142 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00595126 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.00594118 |
| LMNB2 | lamin B2 | -0.00593759 |
| MB | myoglobin | -0.00589282 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00587013 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00585613 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00583223 |
| HELLS | helicase, lymphoid-specific | -0.0058154 |
| PRKCZ | protein kinase C, zeta | -0.00579581 |
| CDCA4 | cell division cycle associated 4 | -0.00579563 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.00578926 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0057793 |
| PRDX1 | peroxiredoxin 1 | -0.00577031 |
| TMEM168 | transmembrane protein 168 | -0.00576914 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00576007 |
| HDAC1 | histone deacetylase 1 | -0.00575532 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00575052 |
| DES | desmin | -0.00574078 |
| SELENBP1 | selenium binding protein 1 | -0.00573441 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | -0.00573347 |
| DALRD3 | DALR anticodon binding domain containing 3 | -0.00573137 |
| HEATR1 | HEAT repeat containing 1 | -0.00572764 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00571921 |
| ADCY7 | adenylate cyclase 7 | -0.00571464 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00571157 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -0.00570451 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00568827 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.0056708 |
| DSG1 | desmoglein 1 | -0.00565095 |
| TWF2 | twinfilin actin binding protein 2 | -0.00564947 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00564847 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | -0.0056359 |
| MAGEA12 | melanoma antigen family A12 | -0.00562769 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00562168 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00561631 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00560686 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00560636 |
| ADA | adenosine deaminase | -0.0055986 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00559363 |
| PCGF2 | polycomb group ring finger 2 | -0.00559252 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.00558633 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00558379 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00558362 |
| SEPTIN9 | septin 9 | -0.00558267 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00558137 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00556596 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00556 |
| EPN2 | epsin 2 | -0.00555548 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00555362 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00555281 |
| GPM6B | glycoprotein M6B | -0.00554674 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00554269 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00553714 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00553508 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.00551961 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.0055196 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00550823 |
| CALR | calreticulin | -0.00550279 |
| TFF2 | trefoil factor 2 | -0.00549782 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00549113 |
| FOXG1 | forkhead box G1 | -0.00546566 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00543904 |
| TMEM254 | transmembrane protein 254 | -0.00543689 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00543578 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00543532 |
| ENO1 | enolase 1, (alpha) | -0.00542203 |
| MYOT | myotilin | -0.00541175 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00539706 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.00539654 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -0.0053916 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0053774 |
| SRI | sorcin | -0.00536569 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00535667 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00534892 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00534713 |
| APOD | apolipoprotein D | -0.00534027 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00533936 |
| NEK2 | NIMA-related kinase 2 | -0.00532737 |
| KRT2 | keratin 2, type II | -0.00531663 |
| TEAD4 | TEA domain family member 4 | -0.00531575 |
