| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | SBI-0640756 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the SBI-0640756_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0892427 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0526265 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0502366 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0389411 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0332942 |
| PTMA | prothymosin, alpha | 0.0314391 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0314045 |
| BRD2 | bromodomain containing 2 | 0.0295484 |
| RPL4 | ribosomal protein L4 | 0.0283503 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.028005 |
| SQSTM1 | sequestosome 1 | 0.027893 |
| BCOR | BCL6 corepressor | 0.0277979 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.025843 |
| HMGB2 | high mobility group box 2 | 0.0255326 |
| NGLY1 | N-glycanase 1 | 0.023469 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0234445 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.02338 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0230699 |
| CLDN4 | claudin 4 | 0.0228809 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0226032 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0225598 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.0224763 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0223071 |
| UBC | ubiquitin C | 0.022241 |
| RAI1 | retinoic acid induced 1 | 0.0220424 |
| ARF1 | ADP-ribosylation factor 1 | 0.021364 |
| ATXN1 | ataxin 1 | 0.0210924 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0207017 |
| H3-3B | H3.3 histone B | 0.0198202 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0195495 |
| ABHD3 | abhydrolase domain containing 3 | 0.0193944 |
| PKM | pyruvate kinase, muscle | 0.0193936 |
| FAM168A | family with sequence similarity 168, member A | 0.0191462 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0189912 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0184903 |
| PHF3 | PHD finger protein 3 | 0.0184503 |
| FLNB | filamin B, beta | 0.0183954 |
| ZNF292 | zinc finger protein 292 | 0.018335 |
| USP53 | ubiquitin specific peptidase 53 | 0.0181162 |
| MKI67 | marker of proliferation Ki-67 | 0.0180697 |
| MED13 | mediator complex subunit 13 | 0.0177723 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0175617 |
| CENPC | centromere protein C | 0.0173813 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.017162 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0171458 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0170103 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0169003 |
| RPL37 | ribosomal protein L37 | 0.0167544 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.0166574 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0166476 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.016634 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0164814 |
| SSBP4 | single stranded DNA binding protein 4 | 0.0164255 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0163182 |
| ZC3H6 | zinc finger CCCH-type containing 6 | 0.0159428 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.0159428 |
| TPM3 | tropomyosin 3 | 0.0158138 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0156932 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0156582 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0155741 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0152386 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 0.0147674 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0146255 |
| USP24 | ubiquitin specific peptidase 24 | 0.0145794 |
| FUS | FUS RNA binding protein | 0.0145379 |
| AHI1 | Abelson helper integration site 1 | 0.0145023 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0144535 |
| FILIP1L | filamin A interacting protein 1-like | 0.0144342 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0144108 |
| TEX10 | testis expressed 10 | 0.0144013 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.01438 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0143434 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0142944 |
| XRRA1 | X-ray radiation resistance associated 1 | 0.0142157 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0141715 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0141518 |
| PLPPR4 | phospholipid phosphatase related 4 | 0.0141311 |
| SMIM12 | small integral membrane protein 12 | 0.0141156 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0140588 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0140551 |
| PYCR2 | pyrroline-5-carboxylate reductase family, member 2 | 0.0140208 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0140194 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0138321 |
| SAP30 | Sin3A-associated protein, 30kDa | 0.0138096 |
| SOD1 | superoxide dismutase 1, soluble | 0.013749 |
| HLA-B | major histocompatibility complex, class I, B | 0.0137011 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0136874 |
| ZNF318 | zinc finger protein 318 | 0.0136369 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.013626 |
| FLNA | filamin A, alpha | 0.0135889 |
| RAD9A | RAD9 homolog A (S. pombe) | 0.0135139 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0135049 |
| LRRC69 | leucine rich repeat containing 69 | 0.0134899 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0134565 |
| OSBP2 | oxysterol binding protein 2 | 0.0134519 |
| RPS12 | ribosomal protein S12 | 0.0134512 |
| GOLGB1 | golgin B1 | 0.013443 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0133284 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0133008 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0132909 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.308841 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.14385 |
| CADM2 | cell adhesion molecule 2 | -0.107639 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0962435 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0896815 |
| VIM | vimentin | -0.0884333 |
| PEG10 | paternally expressed 10 | -0.0879939 |
| MGP | matrix Gla protein | -0.0681255 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0647819 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0548948 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0528653 |
| COL1A2 | collagen, type I, alpha 2 | -0.0490065 |
| MEOX2 | mesenchyme homeobox 2 | -0.0419224 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0409878 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0402269 |
| SMYD3 | SET and MYND domain containing 3 | -0.0361344 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.035234 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0340014 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0329482 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.032709 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0318128 |
| SEPTIN11 | septin 11 | -0.0316435 |
| RPS23 | ribosomal protein S23 | -0.0312053 |
| FER | fer (fps/fes related) tyrosine kinase | -0.030367 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0288124 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0281824 |
| TMSB10 | thymosin beta 10 | -0.0281263 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0272349 |
| NFIA | nuclear factor I/A | -0.0268432 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0261606 |
| RBM25 | RNA binding motif protein 25 | -0.0261603 |
| NFIB | nuclear factor I/B | -0.0260511 |
| PCBP2 | poly(rC) binding protein 2 | -0.0256622 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0254458 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0252289 |
| RAD51B | RAD51 paralog B | -0.0251534 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0250606 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0250433 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0249437 |
| DIAPH3 | diaphanous-related formin 3 | -0.0246798 |
| TCF12 | transcription factor 12 | -0.0245822 |
| SFTPA2 | surfactant protein A2 | -0.0244453 |
| HMGA2 | high mobility group AT-hook 2 | -0.0234901 |
| SRPK2 | SRSF protein kinase 2 | -0.0234244 |
| AK1 | adenylate kinase 1 | -0.0230962 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0229596 |
| ACTG1 | actin gamma 1 | -0.0220759 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0219582 |
| EXOC4 | exocyst complex component 4 | -0.0214978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0212494 |
| TUT4 | terminal uridylyl transferase 4 | -0.0209751 |
| COL5A2 | collagen, type V, alpha 2 | -0.0209372 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0209217 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0208595 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0208584 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0208196 |
| RPL34 | ribosomal protein L34 | -0.0208085 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0207003 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0206871 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0206642 |
| RPS24 | ribosomal protein S24 | -0.0205842 |
| WASF2 | WAS protein family, member 2 | -0.0205119 |
| RPL11 | ribosomal protein L11 | -0.0202775 |
| CANX | calnexin | -0.0202715 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0201573 |
| PRELID2 | PRELI domain containing 2 | -0.0201245 |
| TXNRD1 | thioredoxin reductase 1 | -0.0199299 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0196268 |
| HDAC8 | histone deacetylase 8 | -0.0195356 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0195198 |
| ITGAV | integrin, alpha V | -0.0194825 |
| RPL32 | ribosomal protein L32 | -0.0193042 |
| RPLP0 | ribosomal protein, large, P0 | -0.0192136 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0191753 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0191571 |
| USP34 | ubiquitin specific peptidase 34 | -0.0190643 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0188903 |
| TPM4 | tropomyosin 4 | -0.0187949 |
| HOXA3 | homeobox A3 | -0.0187536 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0186581 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0186508 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0186264 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0185598 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.018499 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0184579 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0183372 |
| RPL8 | ribosomal protein L8 | -0.0181715 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.018111 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0179125 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0177207 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0176701 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0176672 |
| RPS6 | ribosomal protein S6 | -0.0174476 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0173381 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.017273 |
| RHEB | Ras homolog enriched in brain | -0.0172197 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0172074 |
| GPM6B | glycoprotein M6B | -0.0171323 |
| RPS4X | ribosomal protein S4, X-linked | -0.0170877 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0170748 |
